Schizophrenia Not a Single Disease but Multiple Genetically Distinct Disorders

New research shows that schizophrenia isn’t a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness. The research at Washington University School of Medicine in St. Louis is reported online Sept. 15 in The American Journal of Psychiatry.

– Washington University in St. Louis|15-Sep-2014 12:05 AM EDT

UNC Researchers Find Final Pieces to the Circadian Clock Puzzle

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UNC researchers discovered how two genes – Period and Cryptochrome – keep the circadian clocks in cells in proper rhythm with the 24-hour day. The finding has implications for drug development for various diseases including cancer and conditions such as jetlag and season affective disorder.

– University of North Carolina School of Medicine|14-Sep-2014 5:00 PM EDT

How an Ancient Vertebrate Uses Familiar Tools to Build a Strange-Looking Head

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Investigator and Scientific Director Robb Krumlauf, Ph.D. and colleagues show that the sea lamprey Petromyzon marinus, a survivor of ancient jawless vertebrates, exhibits a pattern of gene expression that is reminiscent of its jawed cousins, who evolved much, much later.

– Stowers Institute for Medical Research|14-Sep-2014 1:00 PM EDT

Muscular Dystrophy: Repair the Muscles, Not the Genetic Defect

A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease.

– University of Michigan |14-Sep-2014 1:00 PM EDT

Mindfulness Protects Adults’ Health From the Impacts of Childhood Adversity

Adults who were abused or neglected as children are known to have poorer health, but adults who tend to focus on and accept their reactions to the present moment—or are mindful—report having better health, regardless of their childhood adversity.

– Temple University|12-Sep-2014 4:30 PM EDT

Zebrafish Model of a Learning and Memory Disorder Shows Better Way to Target Treatment

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Using a zebrafish model of a human genetic disease called neurofibromatosis, researchers have found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.

– Perelman School of Medicine at the University of Pennsylvania |12-Sep-2014 4:00 PM EDT

Study Estimates Number of U.S. Women Potentially Impacted by Breast Density Notification Legislation

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To date, the prevalence of women with high mammographic breast density -- a recognized risk factor for breast cancer -- in the U.S. has been largely unknown. Now a new study helps quantify the number of U.S. women with this condition, providing needed data for notification legislation under consideration in several states.

– University of Vermont|12-Sep-2014 4:00 PM EDT

Imaging Fuel Injectors with Neutrons

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Researchers are using neutrons to study the formation of these damage-causing bubbles in fuel injectors.

– Oak Ridge National Laboratory|12-Sep-2014 3:00 PM EDT
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