Scientists at Sanford Burnham Prebys have gained a deeper insight into the intricacies of autophagy, the process in which cells degrade and recycle cellular components.
Nearly one in three Americans between the ages of 50 and 80 put off an in-person appointment for medical care in 2020 because they were worried about exposure to the novel coronavirus, new national poll data show.
A study led by Fernando Colchero, University of Southern Denmark and Susan Alberts, Duke University, North Carolina, that included researchers from 42 institutions across 14 countries, provides new insights into the aging theory "the invariant rate of ageing hypothesis", which states that every species has a relatively fixed rate of aging.
Links between lipid imbalance and disease have been established, in which lipid changes increase the formation of amyloid plaques, a hallmark of Alzheimer's disease. This imbalance inspired researchers to explore the role of lipids comprising the cellular membranes of brain cells. In Biointerphases, the researchers report on the significant role lipids may play in regulating C99, a protein within the amyloid pathway, and disease progression.
The IDSA Foundation announces a call for applications for the 2021 Microbial Pathogenesis in Alzheimer’s Disease Grant. The $1.7 million grant, an increase from $1 million in 2020, will fund the advancement of novel research into possible links between infectious diseases and the causation of Alzheimer’s disease.
A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows.
As the global nonprofit leader in Alzheimer's research and science we have extensively reviewed the clinical trial data for Aduhelm™ (aducanumab).
Until now, systemic biomarkers to measure exercise effects on brain function and that link to relevant metabolic responses were lacking. A study shows a memory biomarker, myokine Cathepsin B (CTSB), increased in older adults following a 26-week structured aerobic exercise training. The positive association between CTSB and cognition, and the substantial modulation of lipid metabolites implicated in dementia, support the beneficial effects of exercise training on brain function and brain health in asymptomatic individuals at risk for Alzheimer’s.
Changing your eating habits or altering your circadian clock can impact healthy fat tissue throughout your lifespan, according to a preclinical study published today in Nature by researchers with The University of Texas Health Science Center at Houston (UTHealth).
DALLAS – June 9, 2021 – A phenomenon in which an RNA named NORAD drives a protein named Pumilio to form liquid droplets in cells, much like oil in water, appears to tightly regulate the activity of Pumilio. A new study led by UT Southwestern scientists suggests that such RNA-driven “phase separation,” in turn, protects against genome instability, premature aging, and neurodegenerative diseases, and may represent a previously unrecognized way for RNAs to regulate cellular processes.
Weakened electrical signals in the brain may be an early warning sign of age-related neurodegenerative diseases such as Alzheimer's disease, suggests a study published today in eLife.
The approval of a new Alzheimer's disease drug is getting a lot of attention, but a recent scientific review of the evidence about dementia prevention shows an important role for primary care providers and patients to modify risk factors and protect brain health over the long term.
Older people need digital skills training to learn to use digital technology more independently, but they also seek digital training opportunities because of the social benefits they offer, according to a recent study from the University of Eastern Finland.
This is the first drug that slows Alzheimer's disease. And, this is the beginning of a completely new future for Alzheimer's treatments. This is a new type of Alzheimer's treatment; it addresses the disease in a way that has never been done before, compared to currently approved drugs. Alzheimer's Association spokespeople are available.
Older Chinese immigrants who adjust to their new cultural environment by learning the language, following the country’s media and socializing with local residents can reduce acculturation gap with their adult children and protect their cognitive function, according to a Rutgers study.
University of Kentucky Neuroscience Professor Greg Gerhardt's new research program will provide answers to long-standing questions about the role of neurotransmitters GABA and glutamate in the progression of Alzheimer’s disease. A culmination of his nearly 40 years of brain research, Gerhardt's study could help to develop new treatments for the disease.
New research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's immune response and affect memory in mice and in humans - even when these secondary events occur outside the brain.
A new measure of brain health developed by researchers at Rush University Medical Center may offer a novel approach to identifying individuals at risk of memory and thinking problems, according to research results published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association on June 1.
Osteoporosis, often synonymous with aging, is a silent disease that targets anyone regardless of age and gender.
Smart LED light bulbs for the elderly, the latest innovation from Chula and its partners, can do more than emitting light. They enhance the contrast among the primary colors of light thereby improving visibility and reducing accidents in the elderly. The product is expected to hit the market in May.
New research led by the University of Kent's School of Psychology has found that some brain activity methods used to detect incriminating memories do not work accurately in older adults.
Researchers at University of California San Diego School of Medicine found that functional impairments among adults aged 50 and older are associated with a higher risk of medical cannabis use; and prescription opioid and tranquilizer/sedative use and misuse.
A study of more than 3 million insured U.S. adult patients under 65 found that nearly 3% take immunosuppressive drugs that may elevate risk for severe COVID-19 symptoms and hospitalization if they became infected. There is growing evidence that immunosuppressive drugs may also reduce the COVID vaccine's efficacy.
A reason for these findings could be due to the fact that Parkinson's patients often also have many risk factors for a severe course of Covid-19.
Though obesity in midlife is linked to an increased risk for Alzheimer’s disease, new research suggests that a high body mass index later in life doesn’t necessarily translate to greater chances of developing the brain disease.
Prompted by a recent alarming rise in cases of colorectal cancer in people younger than 50, an independent expert panel has recommended that individuals of average risk for the disease begin screening exams at 45 years of age instead of the traditional 50. “A concerning increase in colorectal cancer incidence among younger individuals (ie, younger than 50 years; defined as young-onset colorectal cancer) has been documented since the mid-1990s, with 11% of colon cancers and 15% of rectal cancers in 2020 occurring among patients younger than 50 years, compared with 5% and 9%, respectively, in 2010,” said Kimmie Ng, MD, MPH, first author of an editorial in JAMA accompanying the article about the guideline change of the USPSTF.
The development of dementia, often from Alzheimer’s disease, late in life is associated with abnormal blood levels of dozens of proteins up to five years earlier.
Two years ago, the Veterans Affairs healthcare system (VA) began rolling out a new benefit, enabling Veterans to receive urgent care from a network of community providers – rather than visiting a VA emergency department or clinic. Progress toward expanding community care services for Veterans is the focus of a special supplement to the May issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Sounds like crickets chirping and the taste of warm buckwheat pancakes can spark the senses of people with dementia — a fact faculty and students at WVU used to develop a way for those people to experience parts of their cultural past and to relieve stress for their caregivers.
Since the discovery of Alzheimer's disease over a century ago, two hallmarks of the devastating illness have taken center stage.
Lifesprk, leader in whole person senior services, and Tealwood Senior Living, leaders in senior living management, have partnered to bring 35 senior living properties across multiple states under Lifesprk Senior Living.
Contrary to popular belief, a new study from the University of Chicago Medicine found the frequency of abdominal surgery in older adults is decreasing, especially among adults over the age of 85.
Research from Saint Louis University finds that adult patients who have received a Tdap vaccination have a 42% lower risk for dementia, compared with patients who are not vaccinated.
People who feel younger have a greater sense of well-being, better cognitive functioning, less inflammation, lower risk of hospitalization and even live longer than their older-feeling peers. A study published by the American Psychological Association suggests one potential reason for the link between subjective age and health: Feeling younger could help buffer middle-aged and older adults against the damaging effects of stress.
Researchers at UC San Diego have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease, a key step toward eventually testing the approach in humans with the neurodegenerative disease.
Exposure to air pollution, even over the course of just a few weeks, can impede mental performance, according to a new study led by researchers at Columbia University Mailman School of Public Health.
Older people with vision loss are significantly more likely to suffer mild cognitive impairment, which can be a precursor to dementia, according to a new study published in the journal Ageing Clinical and Experimental Research.
Researchers at the Rush Institute of Healthy Aging have found that D-CLIP, a lifestyle education program to prevent diabetes in South Asians with prediabetes increased physical activity by nearly an hour a week.
Hot flashes are a hallmark of the menopause transition.
VGLUT – a glutamate transporter on the membrane of vesicles that carry dopamine – is key to regulating sex differences in the brain’s vulnerability to age-related neuron loss.
New research to be presented this week virtually at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2021 explores the positive and negative effects of lifespan-extending drugs on mitochondrial function and age-related osteoarthritis (OA).
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