Commonly used antiretroviral drugs used to treat HIV and hepatitis B reduce immune cells’ energy production
University of California, Los Angeles (UCLA), Health SciencesNew UCLA-led research suggests that antiretroviral drugs called TAF and TDF directly reduce energy production by mitochondria, structures inside cells that generate the power that cells use to function. Both drugs led to reduced cellular oxygen consumption rates, a measure of the ability of the mitochondria to produce energy, compared with controls.