Feature Channels: Alzheimer's and Dementia

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6-Jan-2016 7:05 AM EST
Study Shows Beneficial Effects of Blocking Brain Inflammation in an Experimental Model of Alzheimer’s
University of Southampton

A University of Southampton-led study has found that blocking a receptor in the brain responsible for regulating immune cells could protect against the memory and behaviour changes seen in the progression of Alzheimer’s disease.

Released: 5-Jan-2016 11:30 AM EST
MIND Diet Listed Seven Times in U.S. News & World Report 2016 “Best Diets” Rankings
RUSH

A diet proven to lower the risk of Alzheimer's disease by as much as 53 percent in participants who adhered to the diet rigorously has also been ranked as the easiest diet to follow by U.S. News & World Report.

Released: 24-Dec-2015 4:05 AM EST
Activity of Brain Proteins Associated with Memory Impairment in Alzheimer’s Identified
University of Haifa

Researchers at the laboratory for research of molecular and cellular mechanisms underlying learning and memory, directed by Prof. Kobi Rosenblum, found that “repairing” the activity led to an improvement in memory. A start-up they established on the basis of the findings will attempt to develop drugs delaying the onset of cognitive symptoms

   
Released: 23-Dec-2015 2:05 PM EST
Two Alzheimer’s Risk Genes Linked to Brain Atrophy, Promise Future Blood Markers
Indiana University

Two genetic variants previously linked to Alzheimer's disease have been more specifically tied to brain atrophy that is characteristic of the disease, and could be the basis for future blood biomarker tests.

Released: 22-Dec-2015 3:05 PM EST
Dementia with Lewy Bodies: Is the Research Ready for Clinical Trials
Alzforum

The most complicated of the age-relating dementing diseases just got a little clearer. Marked by degeneration of both the mind and the body, dementia with Lewy bodies combines aspects of both Alzheimer’s and Parkinson’s. DLB has for years languished in the shadows of its eponymous cousins when it came to recognition and research funding, but a recent, once-in-a-decade international conference showcased progress in better defining what DLB is and setting the stage for therapy trials.

21-Dec-2015 10:05 AM EST
Improving Brain’s Garbage Disposal May Slow Alzheimer’s and Other Neurodegenerative Diseases
Columbia University Irving Medical Center

A drug that boosts activity in the brain’s “garbage disposal” system can decrease levels of toxic proteins associated with Alzheimer’s disease and other neurodegenerative disorders and improve cognition in mice, a new study by neuroscientists at Columbia University Medical Center (CUMC) has found.

Released: 17-Dec-2015 9:05 AM EST
Gerontologist Offers Suggestions for Families Coping with Dementia
Kansas State University

A Kansas State University gerontologist offers tips on coping during the holidays with a family member who has dementia.

Released: 16-Dec-2015 12:05 PM EST
Forgetfulness or Alzheimer's? How to Tell the Difference When Visiting Elderly Loved Ones This Holiday Season
University of Kentucky

The holidays are a time when families get together -- sometimes after long periods apart. How can you tell if Grandma is aging normally, or is perhaps showing signs of serious mental decline? Look for these early signs of dementia in an elderly loved one.

4-Dec-2015 11:05 AM EST
Stress in Older People Increases Risk for Pre-Alzheimer’s Condition
Albert Einstein College of Medicine

Feeling stressed out increases the likelihood that elderly people will develop mild cognitive impairment—often a prelude to full-blown Alzheimer’s disease. In a new study, scientists at Albert Einstein College of Medicine and Montefiore Health System found that highly stressed participants were more than twice as likely to become impaired than those who were not. Because stress is treatable, the results suggest that detecting and treating stress in older people might help delay or even prevent the onset of Alzheimer’s. The findings were published online today in Alzheimer Disease & Associated Disorders.

8-Dec-2015 12:25 PM EST
Scientists Discover New Computerized Linguistic Approach to Detect Alzheimer’s Disease
University Health Network (UHN)

Researchers have discovered how to diagnose Alzheimer’s disease with more than 82 per cent accuracy by evaluating the interplay between four linguistic factors; and developing automated technology to detect these impairments.

Released: 9-Dec-2015 2:05 PM EST
Geometric Study of Brain Cells Could Change Strategies on Alzheimer's
Universitat Autònoma de Barcelona

UAB researchers have found that, contrary to current thinking, astrocytes are repelled by the amyloid plaques that are linked to the disease. pplying mathematical models used for studying the galaxies or interactions between elementary particles, researchers at the Institute of Neuroscience of the Universitat Autònoma de Barcelona, in collaboration with Massachusetts General Hospital, Boston, have analysed the spatial distribution of astrocytes: brain cells that are essential for the correct functioning of neurons.

Released: 9-Dec-2015 1:05 PM EST
Gut Bacteria Make Pomegranate Metabolites That May Protect Against Alzheimer's Disease
American Chemical Society (ACS)

In a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich source of disease-fighting polyphenols, can help protect against the development of Alzheimer's disease. But researchers weren't sure which molecules to thank. A team reports in ACS Chemical Neuroscience that the responsible compounds may be urolithins, which are made when gut bacteria break down the polyphenols in the extract.

Released: 7-Dec-2015 10:05 AM EST
New Mice Help Scientists Understand ALS and Frontotemporal Dementia
Alzforum

Scientists have made several kinds of mice in the hope of mimicking ALS and frontotemporal dementia, diseases caused by mutations in the C9ORF72 gene. Early results indicate that the mutated genes generate unusual RNAs and proteins, but that losing the normal C9ORF72 gene does not kill neurons.

25-Nov-2015 12:05 PM EST
Can Slow Walking Speed in Elderly Signal Alzheimer’s Disease Hallmarks?
American Academy of Neurology (AAN)

How fast elderly people walk may be related to the amount of amyloid they have built up in their brains, even if they don’t yet have symptoms of Alzheimer’s disease, according to a study published in the December 2, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 2-Dec-2015 8:30 AM EST
NYU Langone Medical Center Awarded $7.5 Million to Implement Support Services for Alzheimer’s Caregivers in New York City
NYU Langone Health

NYU Langone Medical Center has been awarded a five-year $7.5 million grant to provide caregivers for individuals with Alzheimer’s disease and other dementias with access to state-of-the-art support programs and services designed to improve quality of life. New York State Governor Andrew M. Cuomo announced in November that $67.6 million has been awarded to nine organizations across the state as part of his Alzheimer's Caregiver Support Initiative to develop programs that support family members and caregivers for New Yorkers living with Alzheimer’s and dementia.

Released: 1-Dec-2015 1:05 PM EST
Antidepressant Medication Protects Against Compounds Linked to Dementia
Loyola Medicine

In addition to treating depression, a commonly used antidepressant medication also protects against compounds that can cause memory loss and dementia, a Loyola University Medical Center study has found.

Released: 30-Nov-2015 6:05 PM EST
UCI Part of US Effort to Find Alzheimer’s Biomarkers in People with Down Syndrome
University of California, Irvine

A University of California, Irvine research team is part of a $37 million national effort to identify biomarkers that will predict the onset of Alzheimer’s disease in people with Down syndrome. UCI pediatric neurologist Dr. Ira Lott and colleagues will receive $4.7 million of that funding from the National Institute on Aging to support his continuing work to uncover the mystery of progressive cognitive impairment seen in some people over 40 with Down syndrome.

Released: 30-Nov-2015 2:05 PM EST
Lewy Body Dementia: Unfamiliar With This Common Disorder?
Mayo Clinic

Lewy body dementia is the second most common type of dementia after Alzheimer’s disease. But if you’re not familiar with it, you’re not alone. “Lewy body dementia is the most common disorder you’ve never heard of,” says Bradley Boeve, M.D., a Mayo Clinic neurologist who will speak at the International Dementia with Lewy Bodies Conference Dec. 1-4 in Fort Lauderdale, Florida.

18-Nov-2015 5:05 PM EST
UAB Study Says Alzheimer’s Plaques Can Also Affect the Brain’s Blood Vessels
University of Alabama at Birmingham

Amyloid beta, the plaque that accumulates in the brains of people with Alzheimer’s disease, may also contribute to Alzheimer’s by interfering with normal blood flow in the brain, according to investigators UAB. In findings published Nov. 23 in the journal Brain, the team shows that when amyloid beta accumulates around blood vessels — where it is known as vascular amyloid — it appears to prevent the brain from properly regulating blood flow, which is essential to normal brain function.

   
21-Nov-2015 11:05 AM EST
Virginia Tech Neuroscientists Take Step in Understanding Cause of Alzheimer's Symptoms
Virginia Tech

Virginia Tech Carilion Research Institute scientists have uncovered a mechanism in the brain that could account for some of the neural degeneration and memory loss in people with Alzheimer’s disease. The researchers, together with scientists at the University of Alabama at Birmingham School of Medicine, discovered that a common symptom of Alzheimer’s disease – the accumulation of amyloid plaques along blood vessels – could be disrupting blood flow in the brain.

Released: 18-Nov-2015 9:05 AM EST
College Studies May Reduce Risk of Dementia for Older Adults, Research Finds
American Psychological Association (APA)

Older adults who take college courses may increase their cognitive capacity and possibly reduce their risk for developing Alzheimer’s disease or other forms of dementia, according to new research published by the American Psychological Association.

Released: 16-Nov-2015 4:05 PM EST
Modulating Brain’s Stress Circuitry Might Prevent Alzheimer’s Disease
UC San Diego Health

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of the brain’s stress circuitry significantly reduces Alzheimer’s disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition. The findings are described in the current online issue of the journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.

Released: 16-Nov-2015 3:05 PM EST
Navigating the Holidays Can Be Difficult for Those with Dementia and Their Families
University of Alabama at Birmingham

Changes in routine, including elaborate plans or scheduling special events, can have an adverse effect on someone suffering from any form of dementia.

Released: 12-Nov-2015 10:05 AM EST
Mayo Clinic Awarded $5.3 Million Federal Grant to Study Vascular Risk Factors in Dementia
Mayo Clinic

Mayo Clinic’s Florida campus was awarded a $5.3 million grant from the National Institutes of Health (NIH) to identify vascular risk factors in aging and dementia, and translate that knowledge into studying potential targets for treatment.

Released: 11-Nov-2015 4:05 AM EST
Orchestra Helps Boost Confidence and Mood for Those with Dementia
Bournemouth University

A special orchestra for people with dementia has helped boost their confidence and mood, according to a new research project.

Released: 10-Nov-2015 4:05 PM EST
Leading FAU Neuroscientist Shares Common Myths and Truths About Alzheimer’s Disease
Florida Atlantic University

More than five million Americans and 15 million caregivers are impacted by Alzheimer's disease. A leading neuroscientist at Florida Atlantic University has developed eight myths and truths about this prevalent form of dementia.

10-Nov-2015 9:00 AM EST
Chemo Crosses Blood-Brain Barrier with Sound Waves; Virtual Press Conference
Newswise

Principal Investigator Takes Questions and Demonstrates Procedure with Video and Animation via Virtual Press Conference Tuesday, November 10th at 1:00 p.m. ET

       
Released: 5-Nov-2015 5:05 AM EST
Potential Solution for Side Effect of Alzheimer’s Immunotherapy Treatment
University of Southampton

Researchers from the University of Southampton have discovered a possible solution for side effects seen in immunotherapy treatment for Alzheimer’s disease.

Released: 4-Nov-2015 4:30 PM EST
New, Three-Minute Test Effectively Diagnoses Lewy Body Dementia
Florida Atlantic University

The late Robin Williams had this form of dementia, which also can cause visual hallucinations and make depression worse. Until now, there has been no way to assess or operationalize many of the cognitive and behavioral symptoms of Lewy Body dementia in clinical practice.

30-Oct-2015 10:05 AM EDT
Estrogen Drug May Not Benefit Women with Alzheimer’s Dementia
American Academy of Neurology (AAN)

An estrogen-like drug, raloxifene, has no demonstrated benefit on memory and thinking skills for women with dementia due to Alzheimer’s disease, according to a study published in the November 4, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 4-Nov-2015 11:05 AM EST
LBDA Website Crashes as Public Responds to New Robin Williams Story
Lewy Body American Association of Colleges of Nursing (AACN)Dementia Association

Yesterday, Susan Williams, Robin Williams’ widow, spoke on Good Morning America (GMA) and in other media, about it taking the past year for her to learn that Robin was suffering from Lewy body dementia (LBD), which she believes led him to take his own life. Susan Williams explained that the original Parkinson’s diagnosis did not cover all of his symptoms, and he was unaware of the LBD diagnosis when he died.

Released: 3-Nov-2015 7:00 AM EST
UNMC/Nebraska Medicine Launches Mind and Brain Health Labs
University of Nebraska Medical Center (UNMC)

Driving simulation and real-world data recording systems will shed light on brain health, functional abilities of people with neurological problems neurological disorders

22-Oct-2015 9:05 PM EDT
Memory Complaints in Older Women May Signal Thinking Problems Decades Later
American Academy of Neurology (AAN)

New research suggests that older women who complain of memory problems may be at higher risk for experiencing diagnosed memory and thinking impairment decades later. The study is published in the October 28, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 28-Oct-2015 2:05 PM EDT
Jet Lag-Like Sleep Disruptions Spur Alzheimer’s Memory, Learning Loss
University of California, Irvine

Chemical changes in brain cells caused by disturbances in the body’s day-night cycle may be a key underlying cause of the learning and memory loss associated with Alzheimer’s disease, according to a University of California, Irvine study.

22-Oct-2015 5:00 PM EDT
Care More Expensive for Dementia Patients and Families in Last Years of Life
Mount Sinai Health System

The cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other causes, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, Dartmouth College and University of California, Los Angeles, and published online today in the journal Annals of Internal Medicine.

Released: 26-Oct-2015 8:30 AM EDT
New, Three-Minute Test Effectively Diagnoses Lewy Body Dementia
Florida Atlantic University

Although Lewy Body disease (LBD) is the second-most-common degenerative disease after Alzheimer’s disease (AD), it’s not exactly a household name. A fast, new test can assess clinical signs and symptoms of this disease, and discriminate between AD and LBD with 96

Released: 22-Oct-2015 9:00 AM EDT
New Technique Permits Cell-Specific Examination of Proteins in Alzheimer’s Disease Brain Tissue
NYU Langone Health

Using 10-year-old archival brain tissue from patients with Alzheimer’s disease, a research team from NYU Langone Medical Center has developed a novel method to examine the structure and function of proteins at the cell level -- providing greater means to study protein changes found in Alzheimer’s disease.

Released: 21-Oct-2015 6:05 PM EDT
Antidepressants and Alzheimer’s DiseaseDrugs Might Boost Recovery in Stroke Patients
Loyola Medicine

Evidence is mounting that drugs used to treat depression and Alzheimer’s disease also can help patients recover from strokes.

Released: 20-Oct-2015 2:05 PM EDT
San Diego Team Combats Memory Loss by Enhancing Brain Function
Scripps Research Institute

A new study, led by scientists at The Scripps Research Institute, the Veterans Affairs San Diego Healthcare System and University of California San Diego School of Medicine shows that increasing a crucial membrane protein in nerve cells within the brain can improve learning and memory in aged mice.

16-Oct-2015 11:05 AM EDT
Building and Breaking Synapses
Thomas Jefferson University

Researchers find a protein that's involved in helping control the architecture of connections between neurons – a basic process involved in both healthy and diseased brains.

Released: 19-Oct-2015 11:00 AM EDT
No Increased Dementia Risk Found in Diagnosed Celiac Patients
Columbia University Irving Medical Center

A new and comprehensive study has found that celiac patients are at no increased risk for dementia before or after their diagnosis of celiac disease.

Released: 15-Oct-2015 12:05 PM EDT
Stem Cell Treatment Lessens Impairments Caused by Dementia with Lewy Bodies
University of California, Irvine

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

2-Oct-2015 1:05 PM EDT
Researchers Learn How to Grow Old Brain Cells
Salk Institute for Biological Studies

The new technique allows scientists to study diseases like Alzheimer’s and Parkinson’s using cells from human patients

   
Released: 8-Oct-2015 10:05 AM EDT
Preventing Memory Loss Before Symptoms Appear
Houston Methodist

The Nantz National Alzheimer Center at Houston Methodist Hospital is part of a landmark clinical trial that looks at removing a key protein from the brain to prevent memory loss at least a decade before symptoms are noticed in healthy older adults.

Released: 5-Oct-2015 3:05 PM EDT
Researchers Identify New Gene Linked to Amyloid Beta Plaque Buildup in Alzheimer's Disease
Indiana University

A multi-institutional team led by scientists at the Indiana University School of Medicine have discovered an immune system gene associated with higher rates of amyloid plaque buildup in the brains of Alzheimer’s patients and older adults at risk for the disease.

Released: 5-Oct-2015 3:05 PM EDT
Women with Alzheimer’s-Related Gene Lose Weight More Sharply After Age 70
SUNY Downstate Health Sciences University

Women with a gene variant (APOEe4 allele) associated with Alzheimer’s disease experience a steeper decline in body mass index (BMI) after age 70 than those women without the version of the gene, whether they go on to develop dementia or not.

25-Sep-2015 9:30 AM EDT
Hundreds of Scientists Gather to Hear Latest Alzheimer's Drug Discovery, Preclinical and Clinical Study Results
Alzheimer's Drug Discovery Foundation

More than 100 of the world’s leading Alzheimer’s drug researchers will gather today and tomorrow at the Hyatt Regency Jersey City to hear the latest developments in the discovery and testing of promising drugs, detection technologies, biomarkers and newly discovered therapeutic targets for preventing, treating and curing Alzheimer’s disease and related dementias. Organized and hosted by the Alzheimer’s Drug Discovery Foundation, the conference is the only scientific meeting dedicated solely to bringing leading academic and industry scientists together to present new research on Alzheimer’s drug discovery and establish partnerships to further their studies.



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