Focus: Cancer Center Featured Story 2

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Four Yale School of Medicine researchers have been elected to the prestigious Connecticut Academy of Science and Engineering (CASE).

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The Connecticut Academy of Science and Engineering has elected 24 of the state’s leading experts in science, engineering, and technology to membership in the academy, including 11 new members from Yale.

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Researchers at The University of Kansas Cancer Center are collaborating on the “lab-on-a-chip,” a testing platform that captures and performs analysis of various biomarkers, which are actively released by tumor cells into blood. Rather than the usual invasive and costly biopsy, the credit-card size devices will screen for circulating markers that are released from cancer cells within patients’ blood.

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Melanoma patients’ response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found in the digestive tract, researchers at The University of Texas MD Anderson Cancer Center report at the ASCO-Society for Immunotherapy in Cancer meeting in Orlando.

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For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma (LGSC), hormone maintenance therapy (HMT) may significantly improve survival, according to a new study from researchers at The University of Texas MD Anderson Cancer Center.

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In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40% chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors.

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In two recent studies, researchers at UC Davis have shown that placental tissue can provide critical information about the epigenetic landscape that influences fetal development.

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UKanQuit, a joint inpatient program between the University of Kansas Medical Center and The University of Kansas Hospital, is helping more smokers quit the habit

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The New Mexico Senate “Lobos” tip off against the House of Representatives “Aggies” on Wednesday, March 1, at Santa Fe High School. The hotly-contested game is a fun event for those on the court, on the bench and in the stands. But everyone knows that the real opponent is cancer.

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Women with early-stage breast cancer who had an intermediate risk recurrence score (RS) from a 21-gene expression assay had similar outcomes, regardless of whether they received chemotherapy, a new study from The University of Texas MD Anderson Cancer finds.

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A recent Yale study may have found a new way to fight brain cancer.

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An analysis of a patient’s deadly brain tumor helped doctors at Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report in the journal Genome Medicine.

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The board of directors for World Conference on Interventional Oncology, a nonprofit association that supports and promotes the field, has established a society to further its mission.

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A recent study from the UCSF Center for Translational and Policy Research on Personalized Medicine and the UCSF Helen Diller Family Comprehensive Cancer Center identified opportunities to address the barriers to coverage of hereditary cancer panels, as published in JNCCN.

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The first successful randomized trial of its kind provides preliminary evidence that telephone-based smoking cessation counseling given to smokers shortly after undergoing lung cancer screening can be effective at helping people stop smoking.

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Molecular Cancer Therapeutics reports on this treatment for hermangiosarcama

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A drug given to reduce the side effects of strong post-surgery pain medications resulting in a reduced length of hospital stay for patients who have undergone major gastrointestinal or bladder cancer procedures is found to have similar benefit for some patients undergoing surgery for testicular cancer. An investigator at Rutgers Cancer Institute of New Jersey explored the impact of alvimopan in those patients who underwent RPLND.

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A bladder cancer drug discovered and developed at The University of Kansas Cancer Center is set to become its first cancer drug to go from bench to bedside.

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Recognizing a critical need to address disparities in cancer care, The University of Texas MD Anderson Cancer Center has been designated as an ECHO superhub for oncology by the ECHO Institute at the University of New Mexico Health Science Center (UNMHSC). MD Anderson is one of just nine ECHO superhub sites in the world and the first focused on oncology.

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HIV/AIDS researchers at Fred Hutchinson Cancer Research Center are pioneering efforts across disciplines to advance preventative and curative approaches against the disease.

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A team from The University of Texas MD Anderson Cancer Center describes this week in the journal Nature a series of preclinical experiments using patient-derived tumor xenografts (PDXs) and mouse models that point to potential treatments for patients with a rapidly-progressing and resistant subgroup of tumor cells.

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Researchers from Memorial Sloan Kettering Cancer Center (MSK) today published a seminal review of the rapidly evolving field of precision oncology, which allows doctors to recommend therapies based on a genetic understanding of a person’s cancer. Appearing in the special cancer-focused February 9 issue of Cell, the article — “Implementing Genome-Driven Oncology” — presents a critically self-reflective but solutions-focused perspective on this approach to cancer treatment.

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A single blood test and basic information about a patient’s medical status can indicate which patients with myelodysplastic syndrome (MDS) are likely to benefit from a stem cell transplant, according to new research by scientists at Dana-Farber Cancer Institute.

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To celebrate Valentine’s Day, The University of New Mexico Lobo Men’s and Women’s basketball teams are joining forces to honor all those who have beaten breast cancer, still face it, or have lost to it. They plan to hold their Lobos Love Pink basketball games during the same week to raise awareness for breast cancer.

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Ludwig researchers discover that circular DNA, once thought to be rare in tumor cells, is actually very common and seems to play a fundamental role in tumor evolution

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Immunotherapy has been a game changer for the oncology field, but typical models used to assess the value of cancer treatments don’t take into account the unique characteristics of this therapy, according to experts at the 2016 annual meeting of the Society for Immunotherapy of Cancer (SITC).

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Breast cancer patients with dense breast tissue have almost a two-fold increased risk of developing disease in the contralateral breast, according to new research from The University of Texas MD Anderson Cancer.

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Eric Prossnitz, PhD and his team uncovered new details of the aging process. They discovered an altered balance between certain signaling molecules in the smooth muscle cells of blood vessels and the heart. The team also discovered a new class of drugs that combats an important part of the aging process.

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The University of Texas MD Anderson Cancer Center returns to Southern California this month with its Making Cancer History® Seminar, 3:30-5:30 p.m. Feb. 20 at the Renaissance Indian Wells Resort and Spa, 44400 Indian Wells Lane.

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Yale researchers found in a study that one in four high schoolers who use electronic cigarettes are inhaling vapors produced by dripping e-liquids directly onto heating coils, instead of inhaling from the e-cigarette mouthpiece, possibly increasing exposure to toxins and nicotine.

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Paulovich’s lab will develop a customized panel of MRM (multiple reaction monitoring)-based assays and deploy these assays to quantify tumor proteins in clinical samples from patients receiving treatment. Other collaborators in the Moonshot project will decide on treatments, track how well the treatments shrink the tumors, and then search for correlations that show whether the tumors’ protein makeup related to how well the patients responded to treatment.

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A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes. The process, which located a genetic site for the most common form of prostate cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer Center. Study results were published in the Feb. 6 online issue of Nature.

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In honor of World Cancer Day on Feb. 4, The University of Texas MD Anderson Cancer Center calls for health care providers, organizations, governments and individuals to unite in the common goal of eliminating cancer. Driven to accelerate progress toward Making Cancer History®, MD Anderson is proud to support this global effort.

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• New Roswell Park spinoff company will develop next-generation cancer immunotherapies • Novel approach combines unique adoptive T cell therapy with genetically engineered stem cell therapy • Clinical trial planned in ovarian, pancreatic, lung, prostate and other hard-to-treat cancers

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A rare look at brain surgery with the patient alert and awake at Smilow Cancer Hospital at Yale-New Haven.

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NCCN has published the NCCN Guidelines for Patients® and NCCN Quick Guide™ sheet for Waldenström’s Macroglobulinemia—a rare, but manageable type of Non-Hodgkin’s Lymphoma.

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In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

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Georgetown Lombardi Comprehensive Cancer Center researchers have used animal models to reveal new information about the impact – positive and negative – that soy consumption could have on a common breast cancer treatment.

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Tudor Oprea, MD, PhD, at UNM Comprehensive Cancer Center and his collaborators from the UK-based European Bioinformatics Institute in Hinxton and from the Institute for Cancer Research in London have created the beginnings of an open archive that links a drug’s chemical structure, its molecular biology activity and the diseases it is used to treat.

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The University of Texas MD Anderson Cancer Center and Guardant Health today announced a multi-year partnership designed to accelerate comprehensive liquid biopsy technology into the standard of care in cancer treatment.

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Three nonprofits partner to create powerful database that will aim to improve immunotherapy for many types of cancer.

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Researchers have uncovered 30 genes that could, one day, serve as therapeutic targets to reverse Rett syndrome, a rare neurological disorder that affects only girls and is a severe form of an autism spectrum disorder.

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In a second human case, a Yale-led research team has found that a melanoma cell and a white blood cell can fuse to form a hybrid with the ability to metastasize. The finding provides further insight into how melanoma and other cancers spread from solid tumors with implications for future treatment.

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What if doctors could look into a crystal ball and predict which of their patients might be at risk of getting sick enough to go to the emergency room? For at least one group of patients, that’s exactly what researchers at Penn Medicine are trying to do.

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Dr. Harold Tara Appointed Medical Director of Smilow Care Centers in Trumbull & Fairfield

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Today, after a yearlong review and collaborative process, Miami Cancer Institute at Baptist Health South Florida became a full member of the Memorial Sloan Kettering (MSK) Cancer Alliance. Miami Cancer Institute is the third member of the MSK Cancer Alliance, a transformative initiative that aims to improve the quality of care and outcomes for people with cancer in community settings.

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Researchers at Dana-Farber Cancer Institute led a study that provides some of the strongest evidence to date that microorganisms living in the large intestine can serve as a link between diet and certain types of colorectal cancer.

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NCCN’s second policy and advocacy fellow will maintain a comprehensive understanding of the oncology policy landscape, contribute to the advancement of NCCN’s policy initiatives, and contribute to the monitoring and awareness of use of NCCN Content by public and private payers to enhance access to and delivery of quality oncology care in the United States.

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BUFFALO, N.Y. — More than 1 in 4 adults and nearly 1 in 10 youth use tobacco, according to findings from the Population Assessment of Tobacco and Health (PATH) Study, published online ahead of print in the New England Journal of Medicine. The PATH Study, established in 2011 through collaboration between the National Institutes of Health’s National Institute on Drug Abuse and the U.S. Food and Drug Administration’s Center for Tobacco Products, is a uniquely large, nationally representative longitudinal study designed to examine tobacco use behaviors and health among the U.S. population over multiple years of follow-up. The PATH Study is being conducted by Westat of Rockville, Md., with Roswell Park Cancer Institute as the scientific lead.