Feature Channels: Cardiovascular Health

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Researchers from the Perelman School of Medicine at the University of Pennsylvania found that patients taking prescription potassium supplements together with loop diuretics for heart failure have better survival rates than patients taking diuretics without the potassium. Moreover, the degree of benefit increases with higher diuretic doses

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An abdominal aortic aneurysm is a potentially life-threatening condition: If the body’s major blood vessel ruptures, it can prove deadly. The U.S. Preventive Services Task Force recently updated its recommendations on screening.

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Fewer Americans are having strokes and those who do have a lower risk of dying from them finds a new study led by Johns Hopkins Bloomberg School of Public Health researchers.

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Reducing the amount of alcoholic beverages consumed, even for light-to-moderate drinkers, may improve cardiovascular health, including a reduced risk of coronary heart disease, lower body mass index (BMI) and blood pressure, according to a new multi-center study published in The BMJ and co-led by the Perelman School of Medicine at the University of Pennsylvania. The latest findings call into question previous studies which suggest that consuming light-to-moderate amounts of alcohol (0.6-0.8 fluid ounces/day) may have a protective effect on cardiovascular health.

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Mary York's heart broke when she heard her husband of 65 years say he didn't want to live anymore. UAB physicians were able to repair his heart — and ultimately hers, too — when her husband became one of the first in Alabama to receive a MitraClip.

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For children and teens living with a cardiac pacemaker, a low sense of self-competence seems to contribute to decreased quality of life, reports a study in the July Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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In an analysis of about 460 patients with failed bioprosthetic aortic valves who underwent transcatheter valve-in-valve implantation, overall survival at one year was 83 percent, with survival associated with surgical valve size and mechanism of failure, according to a study in the July 9 issue of JAMA.

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The new FDA-approved transcatheter heart valve therapy helps patients with aortic valve disease who are at high risk to undergo open-heart surgery.

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Cardiologists at UT Southwestern Medical Center found that sedentary behaviors may lower cardiorespiratory fitness levels.

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Bone marrow fat may have untapped health benefits, new research finds.

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Charles H. Hennekens, M.D., Dr.P.H., the first to discover that aspirin prevents a first heart attack and is of lifesaving benefit when given during a heart attack or among long-term survivors, was invited by the editor of Nature Reviews: Cardiology to provide perspectives on the recent FDA statements that any decision to use aspirin should be an individual clinical judgment by healthcare providers. The editorial provides updates to clinicians and their patients on the optimal use of aspirin for the treatment and prevention of a first heart attack.

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Use of catheter ablation is not only beneficial for treating atrial flutter but also can significantly reduce hospital visits – both inpatient and emergency – and lower the risk for atrial fibrillation, according to research by UC San Francisco.

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Analysis of pooled data by Paolo Boffetta, MD, Director of the Institute for Translational Epidemiology and Associate Director for Population Sciences of the Tisch Cancer Institute at Mount Sinai, and collaborators showed a strong association between low vitamin D levels and risk of death in general death from cardiovascular diseases, death in from cancer, at least in older people with a history of cancer.

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Valentin Fuster, MD, PhD, of Mount Sinai Heart and other leading global experts have created a free, special magazine issue with Scientific American called “Promoting Cardiovascular Health Worldwide,” focusing on the growing worldwide epidemic of cardiovascular diseases and solutions to improve the promotion of cardiovascular health and prevention of cardiovascular diseases globally.

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A new study by New York Institute of Technology's A. Martin Gerdes, Ph.D. draws links between thyroid hormones and cardiac function in patients with diabetes and heart disease. Restoring normal levels of thyroid hormones prevented the progression of heart disease in rats with diabetes.

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Loyola University Chicago recently hosted a meeting of more than 60 of the world’s leading researchers of a protein that could hold the key to new treatments for heart disease.

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African American women respond differently to the anti-inflammatory effect of aspirin than do white American women, new research finds. The results were presented Monday, June 23 at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.

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Women with Type 2 diabetes and high cholesterol are less likely than their male peers to reach treatment goals to lower their “bad” cholesterol, or low-density lipoprotein (LDL) cholesterol, despite access to cholesterol-lowering medication, a Canadian study finds. The results were presented on Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

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Developed for patients with bradycardia — a heart rate that is too slow — the Nanostim device is designed to be placed directly on the patient’s heart without the visible lump, scar and insulated wires, or leads, required for conventional pacemakers.

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Researchers have identified the first genetic variations linked to race that begin to explain a higher risk of death among some African American and Caucasian patients taking the anti-clotting drug clopidogrel (Plavix) after a heart attack.

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Stem cell therapy for cardiovascular disease isn’t a medical pipe dream – it’s a reality today, although patients need to better understand the complex science behind these experimental treatments, according to the chief of Cardiology for the Cedars-Sinai Heart Institute.

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For decades, common medical wisdom has been “the lower the better” in treating the approximately one in three people in this country who have high blood pressure. But does that approach result in reduced risk for dangerous heart events?

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Researchers at the University of Montreal and CHUM Research Centre (CRCHUM) recently demonstrated the potential of retinoic acid (RA), a derivative of Vitamin A, in treating obesity and type 2 diabetes and preventing their cardiovascular complications.

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Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with a variety of cardiovascular risk factors, including inflammation, insulin resistance, abnormal cholesterol, and high blood pressure. While effective therapies are available for OSA, researchers are still unclear about what interventions are most effective in reducing the burden of risk factors for cardiovascular disease associated with OSA in obese patients. New research from a multidisciplinary team at the Perelman School of Medicine at the University of Pennsylvania now reveals that the single most important factor for improving cardiovascular health in obese OSA patients is weight loss. The study results are published in the New England Journal of Medicine.

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“Excessive iron is believed to contribute to heart disease and donating blood reduces the iron stores in the body,” said Ivan Pacold, MD, chair, Cardiology Department, Loyola’s Gottlieb Memorial Hospital. “Plus you get a mini-assessment each time you give blood to reinforce wellness."

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Children with heart disease are exposed to low levels of radiation during X-rays, which do not significantly raise their lifetime cancer risk. However, children who undergo repeated complex imaging tests that deliver higher doses of radiation may have a slightly increased lifetime risk of cancer, according to researchers at Duke Medicine.

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Doctors at The Ohio State University Wexner Medical Center are the first in the country to begin treating some heart failure patients with a new wireless, implantable hemodynamic monitor that was just approved by the FDA.

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Mount Sinai Heart will host its innovative and prestigious 17th Annual 2014 Live Symposium of Complex Coronary, Valvular, and Vascular Cases June 10-13 at The Mount Sinai Hospital.

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A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile – based on a simple blood test – may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.

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An analysis of more than 600 class I (procedure/treatment should be performed/administered) American College of Cardiology/American Heart Association guideline recommendations published or revised since 1998 finds that about 80 percent were retained at the time of the next guideline revision, and that recommendations not supported by multiple randomized studies were more likely to be downgraded, reversed, or omitted, according to a study in the May 28 issue of JAMA.

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A genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells, Johns Hopkins scientists report. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding DNA, a growing focus of disease research. The discovery also adds to scientific understanding of the causes of sudden cardiac death and of possible ways to prevent it, the researchers say.

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Couples may take longer to conceive a child when one or both partners has high cholesterol, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

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Johns Hopkins researchers say they have developed a technique that can predict — with 95 percent accuracy — which stroke victims will benefit from intravenous, clot-busting drugs and which will suffer dangerous and potentially lethal bleeding in the brain.

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Taking olive oil supplements may counteract some of the adverse cardiovascular effects of exposure to air pollution, according to a new study presented at the 2014 American Thoracic Society International Conference.

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Researchers at the Cedars-Sinai Heart Institute have identified a heart-specific form of a protein, BIN1, responsible for sculpting tiny folds in pockets that are present on the surface of heart muscle cells. The study provides the first direct evidence of a previously theoretical “fuzzy space” or “slow diffusion zone” that protects against irregular heartbeats by maintaining an ideal concentration of electrochemical molecules.

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A team led by Maciej Goniewicz of Roswell Park Cancer Institute found that high-voltage electronic cigarettes may expose users to increased levels of toxic chemicals, including formaldehyde and acetaldehyde.

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A new stent has been effective at keeping arteries open in the lower extremities of patients with peripheral artery disease for more than four years.

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Today, the American Medical Group Foundation (AMGF) announced that nearly 70 organizations will participate in the inaugural Measure Up/Pressure Down® National Day of Action: Roll Up Your Sleeves! event on May 15, 2014.

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Even if treated, hypertension and high cholesterol are increasingly common for people with human immunodeficiency virus (HIV), according to a new study from researchers at Mount Sinai St. Luke’s and Mount Sinai Roosevelt hospitals in New York and the University of California, Davis.

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Mount Sinai study shows the socioeconomic status of congestive heart failure patients does not influence hospital rankings for heart failure readmissions.

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A new study by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City has found that atrial fibrillation patients who are on blood thinning medications are at higher risk of developing dementia if their doses are not in the optimal recommended range.

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Vivek Reddy, MD, Director of Arrhythmia Services for The Mount Sinai Hospital, reported his promising12-month follow-up data showing the world’s first leadless pacemaker is demonstrating overall device performance comparable to conventional pacemakers. Dr. Reddy presented the one-year LEADLESS study data findings during his late-breaking clinical trial presentation on May 9 at Heart Rhythm 2014, the Heart Rhythm Society’s 35th Annual Scientific Sessions in San Francisco, CA.

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New research from McMaster University suggests that a commonly performed test during certain types of heart surgery is not helpful and possibly harmful.

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Experts from the Penn Medicine Cardiovascular Institute and the Cardiac Arrhythmia Program will present new research and participate in expert panel discussions at the 35th Annual Scientific Sessions of the Heart Rhythm Society (HRS) May 7-10, 2014 in San Francisco.

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Investigators at the Cedars-Sinai Heart Institute – whose previous research showed that cardiac stem cell therapy reduces scarring and regenerates healthy tissue after a heart attack in humans – have identified components of those stem cells responsible for the beneficial effects.

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Tired legs? Women face greater limits on their lifestyle due to peripheral artery disease, but benefit just as well as men from minimally invasive procedures to unclog their arteries. Study shows docs need to ask women more often about leg discomfort and screen for PAD.

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Notah Begay III, four-time PGA Tour Winner, golf analyst and founder of the Notah Begay III (NB3) Foundation suffered a heart attack last week in Dallas. He received a stent to unblock his right coronary artery and is expected to make a full recovery, according to a statement made by his Foundation.

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Exercise-induced body temperature increases can make symptoms worse for some patients with multiple sclerosis. Researchers at Southern Methodist explore the underlying causes of the temperature regulation problems so MS patients can better reap the benefits of exercise.

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A new device called a subcutaneous implantable cardioverter defibrillator (S-ICD) prevents sudden cardiac death with an electric shock. A conductor wire is implanted just under the skin, rather than going into the heart. In carefully selected patients, a S-ICD can reduce the risk of bleeding, blood clots and bloodstream infections, compared with a defibrillator with leads that go into the heart,

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People who took statins in the 2009–10 year were consuming more calories and fat than those who used statins 10 years earlier. There was no similar increase in caloric and fat intake among non–stain users during that decade.