Curated News: JAMA

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Released: 29-Jan-2016 2:05 PM EST
Awareness of Aspirin's Benefits Saves Lives
University of Minnesota

A new study published in the Journal of the American Heart Association has found that the University of Minnesota's "Ask About Aspirin" initiative, a statewide public health campaign, is likely a beneficial and cost-effective way to reduce the incidence of a first heart attack or stroke.

Released: 29-Jan-2016 2:05 PM EST
Awareness of Aspirin's Benefits Saves Lives
University of Minnesota

A new study published in the Journal of the American Heart Association has found that the University of Minnesota's "Ask About Aspirin" initiative, a statewide public health campaign, is likely a beneficial and cost-effective way to reduce the incidence of a first heart attack or stroke.

27-Jan-2016 9:05 AM EST
Evidence Lacking to Support Use of Costlier Biologic Mesh for Abdominal Hernia Repair
UT Southwestern Medical Center

A UT Southwestern Medical Center study comparing two types of materials used in abdominal wall hernia repair surgery found no evidence to support the use of costlier biologic mesh versus synthetic mesh.

Released: 27-Jan-2016 8:05 AM EST
Twenty-Five-Point Drop in IQ Caused by Lack of Gene Copy
Universite de Montreal

Researchers measured the intelligence of 700 family members who had at least one relative carrying the same genetic mutation on chromosome 16, which is known to predispose to autistic spectrum disorders. Even in study participants whose IQ was considered to be normal, the researchers found a substantial 25 points IQ drop induced by 16p11.2 gene deletions.

22-Jan-2016 4:05 PM EST
Regular Caffeine Consumption Does Not Result in Extra Heartbeats, Study Shows
University of California, San Francisco (UCSF)

Contrary to current clinical belief, regular caffeine consumption does not lead to extra heartbeats, which, while common, can lead in rare cases to heart- or stroke-related morbidity and mortality, according to UC San Francisco researchers.

20-Jan-2016 4:30 PM EST
Study Examines Link Between HPV and Risk of Head and Neck Cancers
Albert Einstein College of Medicine

Researchers, led by Ilir Agalliu, M.D., and Robert Burk, M.D., at Albert Einstein College of Medicine have found that when human papillomavirus (HPV)-16 is detected in peoples’ mouths, they are 22 times more likely than those without HPV-16 to develop a common type of head and neck cancer.

19-Jan-2016 11:00 AM EST
Novel Study Shows Lower Surgical Mortality in Hospitals with Best Nursing Care
University of Pennsylvania School of Nursing

Patients are often unaware that choosing the right hospital is very important to having a good outcome. A novel study published today in the prominent surgery journal JAMA Surgery showed that patients undergoing surgery at Magnet hospitals recognized for nursing excellence, and good nurse staffing, have better outcomes at the same or lower costs as other hospitals.

14-Jan-2016 4:30 PM EST
Low-Cost Tool In Fight Against Childhood Obesity: Water Dispensers in NYC Schools Associated with Student Weight Loss
NYU Langone Health

Making water more available in New York City public schools through self-serve water dispensers in cafeterias resulted in small -- but statistically significant -- declines in students’ weight, according to new findings.

15-Jan-2016 10:00 AM EST
Current Therapy for Patients with Parkinson’s Disease Shown to Be Ineffective
University of Birmingham

New research from the University of Birmingham has shown that physiotherapy and occupational therapy do not produce improvements in quality of life for patients with mild to moderate Parkinson’s disease.

15-Jan-2016 11:05 AM EST
Cost of End-of-Life Care in the U.S. Is Comparable to Europe and Canada, Finds New Penn Study
Perelman School of Medicine at the University of Pennsylvania

Despite widespread perception, the United States does not provide the worst end-of-life care in the world. In the first international comparison of end-of-life care practices, researchers from the Perelman School of Medicine at the University of Pennsylvania and colleagues from seven countries found that the United States actually has the lowest proportion of deaths in the hospital and the lowest number of days in the hospital in the last six months of life among the those countries, according to a new study published today in JAMA.

15-Jan-2016 3:05 PM EST
Slow Heart Rate Does Not Increase Risk of Heart Disease
Atrium Health Wake Forest Baptist

Bradycardia – a slower than normal heartbeat – does not increase the risk of developing cardiovascular disease, according to a study conducted by researchers at Wake Forest Baptist Medical Center. The study is published in the Jan.19 online edition of the Journal of American Medical Association Internal Medicine.

15-Jan-2016 4:05 PM EST
Researchers Advocate Improvements in End-of-Life Care
Dana-Farber Cancer Institute

Three Dana-Farber Cancer Institute researchers, writing in a special issue of JAMA published today, make the case for policies and practices that give terminally ill patients more control over how and where they will die

15-Jan-2016 11:05 AM EST
Georgetown Public Health Experts: Congress Made a “Scientific Judgment for Which It Is Distinctly Unqualified”
Lombardi Comprehensive Cancer Center at Georgetown University

Two Georgetown University professors say a section of the recently passed Congressional spending bill effectively undermines science and the health of women. Their JAMA Viewpoint, “A Public Health Framework for Screening Mammography: Evidence-Based Versus Politically Mandated Care,” will be published online Tuesday.

Released: 14-Jan-2016 11:05 AM EST
Frozen Poop Just as Good as Fresh for C. diff Patients
University of Guelph

Frozen fecal transplantation is just as effective at providing relief to Clostridium difficile (C. diff) patients as fresh microbiota transplantation, according to a new study co-authored by University of Guelph researchers.

Released: 12-Jan-2016 2:05 PM EST
New Study Shows Vitamin D Supplements May Cause Falling
California Pacific Medical Center Research Institute

According to new research summarized by California Pacific Medical Center Research Institute senior scientist Steven Cummings, MD, and colleagues at the University of California, San Francisco (UCSF) and Harvard Medical School, contrary to common beliefs, relatively high doses of vitamin D may increase the risk of falls.

7-Jan-2016 1:05 PM EST
New Tool Estimates Looming Risk of Kidney Failure in People with Kidney Disease
Johns Hopkins Bloomberg School of Public Health

An online tool combining results of common medical tests can accurately estimate the risk of whether someone with chronic kidney disease will develop kidney failure in the next two to five years, an international team of researchers led by the Johns Hopkins Bloomberg School of Public Health has found.

Released: 5-Jan-2016 11:05 AM EST
Vanderbilt Study Raises Questions About Reporting Incidental Genetic Findings
Vanderbilt University Medical Center

The study of 2,022 patients identified 63 who had genetic variations considered to be “potentially pathogenic” – capable of producing arrhythmias. Yet their electrocardiograms (ECGs) were no different from those who did not carry the “disease genes.”

Released: 29-Dec-2015 3:05 PM EST
New Breast Cancer Drug May Be Effective Against Other Types of Cancer, Abramson Cancer Center Experts Find
Perelman School of Medicine at the University of Pennsylvania

Palbociclib, a new oral drug whose efficacy in combating breast cancer has been demonstrated alone and in combination with endocrine therapy, also has potential to combat other types of cancer, according to a literature review and additional original research conducted by experts at the Abramson Cancer Center in the University of Pennsylvania published this month in JAMA Oncology.

Released: 21-Dec-2015 11:05 AM EST
Low Blood Flow in Back of Brain Increases Risk of Recurrent Stroke
University of Illinois Chicago

Patients who have had a stroke in the back of the brain are at greater risk of having another within two years if blood flow to the region is diminished, according to results of a multicenter study led by researchers at the University of Illinois at Chicago.

15-Dec-2015 11:00 AM EST
Family Members at Higher Risk When Cancers of Unknown Origin Strike Relatives
University of Utah Health

When a cancer of unknown origin strikes, patients' family members are at a higher risk for those and other types of cancer.

15-Dec-2015 3:45 PM EST
Early Childhood Depression Alters Brain Development​
Washington University in St. Louis

The brains of children who suffer clinical depression as preschoolers develop abnormally, compared with the brains of preschoolers unaffected by the disorder, according to new research at Washington University School of Medicine in St. Louis. Their gray matter is lower in volume and thinner in the cortex, a part of the brain important in the processing of emotions.

Released: 15-Dec-2015 3:05 PM EST
Study Finds that Eliminating Cost for Colorectal Cancer Screening Doesn’t Improve Screening Rates
University Hospitals Cleveland Medical Center

Making colonoscopy available at no cost to eligible Medicare beneficiaries under the Affordable Care Act (ACA) did not increase the number of people in this target population who regularly undergo the procedure, says a new large scale national study from University Hospitals Case Medical Center Seidman Cancer Center. Interestingly, the same analysis found that rates of routine mammography significantly increased following the ACA’s mandate for low or no cost screenings for Medicare recipients.

10-Dec-2015 7:05 AM EST
Taking Antidepressants During Pregnancy Increases Risk of Autism by 87%
Universite de Montreal

Using antidepressants during pregnancy greatly increases the risk of autism, Professor Anick Bérard of the University of Montreal and its affiliated CHU Sainte-Justine children’s hospital revealed today

10-Dec-2015 11:00 AM EST
Delaying Chemotherapy in Breast Cancer Patients Reduces Overall Survival, Especially for Those with Triple-Negative Breast Cancer
University of Texas MD Anderson Cancer Center

Postponing the start of adjuvant chemotherapy for more than 90 days following surgery may significantly increase risk of death for breast cancer patients, particularly those with triple-negative breast cancer (TNBC), according to a new study from The University of Texas MD Anderson Cancer Center.

Released: 9-Dec-2015 4:05 PM EST
Is Stroke Prevention Taking a Back Seat to Stroke Treatment?
University of California, Irvine

Many strokes that required immediate treatment in emergency rooms may have been preventable, according to a University of California, Irvine study. While therapy for acute stroke continues to advance and improve patient outcomes, the findings stress that stroke prevention – including the close monitoring of blood pressure, cholesterol levels and cardiac conditions – needs to keep pace.

Released: 9-Dec-2015 3:05 PM EST
Recently Approved Heart Drug Poses Potential Risk to Brain & Eye, Temple Researcher Warns
Temple University Health System

Patients with mild heart failure stand to benefit from a new drug that can halt the progression of their disease and reduce their risk of cardiovascular-related death. But the drug -- a tablet that combines the agents valsartan and sacubitril, sold under the trade name Entresto by drugmaker Novartis -- may be too good to be true, according to Arthur M. Feldman, MD, PhD, Executive Dean of the Lewis Katz School of Medicine at Temple University (LKSOM), Chief Academic Officer of the Temple University Health System, and Laura H. Carnell Professor of Medicine at LKSOM.

Released: 9-Dec-2015 3:05 PM EST
Recently Approved Heart Drug Poses Potential Risk to Brain & Eye, Temple Researcher Warns
Temple University Health System

Patients with mild heart failure stand to benefit from a new drug that can halt the progression of their disease and reduce their risk of cardiovascular-related death. But the drug -- a tablet that combines the agents valsartan and sacubitril, sold under the trade name Entresto by drugmaker Novartis -- may be too good to be true, according to Arthur M. Feldman, MD, PhD, Executive Dean of the Lewis Katz School of Medicine at Temple University (LKSOM), Chief Academic Officer of the Temple University Health System, and Laura H. Carnell Professor of Medicine at LKSOM.

3-Dec-2015 4:05 PM EST
One in Four New Doctors May Be Depressed – and Their Patients May Suffer Because of It
Michigan Medicine - University of Michigan

More than one in four doctors in the early stages of their careers has signs of depression, a comprehensive new study finds. And the grueling years of training for a medical career may deserve some of the blame.

8-Dec-2015 9:05 AM EST
Medical Student Presence Does Not Slow Care in Emergency Departments, Penn Medicine Study Finds
Perelman School of Medicine at the University of Pennsylvania

Medical students in Emergency Departments often perform an initial evaluation of stable patients prior to supervising residents or attending physicians, who meanwhile provide care to other patients. Despite some concern over the possible effect to patients, new research shows the presence of medical students in the Emergency Department adds less than five minutes to the average length of a patient’s stay. The findings, from a team of researchers at the Perelman School of Medicine at the University of Pennsylvania, are published in the December 8 Medical Education issue of JAMA.

30-Nov-2015 4:00 PM EST
U-M Researchers Find Adults with Cerebral Palsy More Likely to Have Chronic Health Conditions
Michigan Medicine - University of Michigan

A new study from the University of Michigan finds adults with cerebral palsy are more likely to have secondary chronic health conditions, such as diabetes and high blood pressure, than adults without cerebral palsy.

23-Nov-2015 9:10 AM EST
NYU Langone Enhances Patient Experience by Reducing Referrals to Rehab Facilities after Major Surgery
NYU Langone Health

NYU Langone study finds referring a patient to an acute care facility after major surgery, rather than the patient’s own home, may not always be necessary.

Released: 19-Nov-2015 11:05 AM EST
Can a Website Keep Suicidal Thoughts Away? Study in Stressed Young Doctors Suggests So
Michigan Medicine - University of Michigan

If you think your life is stressful, try being a new doctor. Their first year especially is a time of stress, sleeplessness and self-doubt – and four times the usual rate of suicidal thoughts. But a new study shows that a free web-based tool to support their mental health may cut that rate in half.

12-Nov-2015 4:05 PM EST
Studies Find Decline in Rates of PSA Screening, Early-Stage Prostate Cancer
JAMA - Journal of the American Medical Association

Two studies in the November 17 issue of JAMA examine the change in prostate-specific antigen (PSA) screening and prostate cancer incidence before and after the 2012 U.S. Preventive Services Task Force (USPSTF) screening recommendations.

12-Nov-2015 4:05 PM EST
Early Use of Antibiotic for Recurrent, Severe Lower Respiratory Illness in Children
JAMA - Journal of the American Medical Association

Among young children with histories of recurrent severe lower respiratory tract illness (LRTI), the use of azithromycin early during an apparent RTI compared with placebo significantly reduced the risk of experiencing progression to severe LRTI, according to a study in the November 17 issue of JAMA.

12-Nov-2015 4:05 PM EST
Study Compares Risk of Anaphylaxis Among Marketed IV Iron Products
JAMA - Journal of the American Medical Association

Cunlin Wang, M.D., Ph.D., of the U.S. Food and Drug Administration, Silver Spring, Md., and colleagues studied recipients of intravenous (IV) iron (n = 688,183) enrolled in the fee-for-service Medicare program from January 2003 to December 2013. The study appears in the November 17 issue of JAMA.

16-Nov-2015 4:05 PM EST
For Kids Prone to Wheezing with Respiratory Infections, Early Antibiotics Help​
Washington University in St. Louis

In children whose colds tend to progress and lead to severe wheezing and difficulty breathing — such that they are given oral corticosteroids as rescue therapy — researchers have shown that giving a common antibiotic at the first sign of cold symptoms can reduce the risk of the episode developing into a severe lower respiratory tract illness. The new study, led by researchers at Washington University School of Medicine in St. Louis, appears online Nov. 17 in JAMA.

16-Nov-2015 10:00 AM EST
National Study: For Low-Income Children, Preventive Care Is More Likely in Medicaid and CHIP Than Under Private Insurance
Children's Hospital of Philadelphia

Researchers say that children in low-income families experience greater access to preventive medical and dental care under Medicaid or the Children’s Health Insurance Program than children covered by private insurance. However, for all types of insurance, access to pediatric specialty care is a challenge.

Released: 9-Nov-2015 3:05 PM EST
Mayo Clinic Study: One Energy Drink May Increase Heart Disease Risk in Young Adults
Mayo Clinic

New research shows that drinking one 16-ounce energy drink can increase blood pressure and stress hormone responses significantly. This raises the concern that these response changes could increase the risk of cardiovascular events.

Released: 9-Nov-2015 2:05 PM EST
Use of Rarely Appropriate Angioplasty Procedures Declined Sharply
American College of Cardiology (ACC)

The number of angioplasty procedures classified as rarely appropriate declined sharply between 2010 and 2014, as did the number of those performed on patients with non-acute conditions, according to a study published today in the Journal of the American Medical Association and simultaneously presented at a meeting of the American Heart Association in Orlando.

Released: 9-Nov-2015 2:05 PM EST
Use of Rarely Appropriate Angioplasty Procedures Declined Sharply
American College of Cardiology (ACC)

The number of angioplasty procedures classified as rarely appropriate declined sharply between 2010 and 2014, as did the number of those performed on patients with non-acute conditions, according to a study published today in the Journal of the American Medical Association and simultaneously presented at a meeting of the American Heart Association in Orlando.

6-Nov-2015 3:05 PM EST
Penn Study Asks: To Improve Patients’ Health, Should you Pay Physicians, Patients, or Both?
Perelman School of Medicine at the University of Pennsylvania

Providing financial incentives to both primary care physicians and patients leads to a greater reduction in low-density lipoprotein (LDL) cholesterol in patients than paying only the physician or only the patient, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, which is the first to test physician-only and patient-only incentives compared to incentives shared by patients and physicians, is published in the November 10 issue of JAMA.

3-Nov-2015 4:30 PM EST
First Precision Medicine Trial in Cancer Prevention Identifies Molecular-based Chemoprevention Strategy
UC San Diego Health

A team of scientists, led by researchers at University of California, San Diego Moores Cancer Center and The University of Texas MD Anderson Cancer Center, report that a genetic biomarker called loss of heterozygosity or LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer. The findings, published in the November 5, 2015 online issue of Journal of the American Medical Association Oncology, present a new tool that could be used to identify patients most likely to benefit from chemoprevention — and may be applicable to preventing other types of cancer.

Released: 2-Nov-2015 11:45 AM EST
Conventional Heart Drug Stops the Progression of Cancer
Texas Tech University Health Sciences Center El Paso

A common heart drug may stop the progression of angiosarcoma, a cancer of the inner lining of blood vessels, according to a study by researchers at Texas Tech University Health Sciences Center (TTUHSC) El Paso.

Released: 28-Oct-2015 1:05 PM EDT
Marital Status Linked to Better Functional Outcomes Following Cardiac Surgery, Penn Medicine Study Finds
Perelman School of Medicine at the University of Pennsylvania

Patients who are divorced, separated or widowed had an approximately 40 percent greater chance of dying or developing a new functional disability in the first two years following cardiac surgery than their married peers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania published in this week’s JAMA Surgery.

22-Oct-2015 4:05 PM EDT
Decreases Seen in Leading Causes of Death
JAMA - Journal of the American Medical Association

An analysis of deaths in the United States between 1969 and 2013 finds an overall decreasing trend in the age-standardized death rate for all causes combined and for heart disease, cancer, stroke, unintentional injuries, and diabetes, although the rate of decrease appears to have slowed for heart disease, stroke, and diabetes, according to a study in the October 27 issue of JAMA.

22-Oct-2015 4:05 PM EDT
Study Compares Combination Treatments for Black Adults with Asthma
JAMA - Journal of the American Medical Association

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

22-Oct-2015 4:05 PM EDT
Study Examines Lack of Specialists in Insurance Plans of Affordable Care Act
JAMA - Journal of the American Medical Association

In a study of federal marketplace insurance plans, nearly 15 percent completely lacked in-network physicians for at least 1 specialty, a practice found among multiple states and issuers, raising concerns regarding patient access to specialty care, according to a study in the October 27 issue of JAMA.

22-Oct-2015 1:00 PM EDT
Too Much, Too Late: Doctors Should Cut Back on Some Medications in Seniors, Two Studies Suggest
Michigan Medicine - University of Michigan

Anyone who takes medicine to get their blood sugar or blood pressure down – or both – knows their doctor prescribed it to help them. But what if stopping, or at least cutting back on, such drugs could help even more? Two new studies suggest doctors should be doing that more.

Released: 22-Oct-2015 9:05 AM EDT
Preeclampsia Increases Risk of Heart Defects in Infants
Universite de Montreal

Pregnant women with preeclampsia have a higher risk of delivering an infant with a congenital heart defect.

Released: 21-Oct-2015 2:45 PM EDT
American Cancer Society Revises Mammogram Guidelines, Causing Some Confusion
Newswise Trends

The American Cancer Society has issued new recommendations on when women should get mammograms and how frequently they should get them. This is in contrast to the previous guidelines which stated that women should get them at age 40.



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