A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice. This landmark study appears today in Nature Biotechnology (early online edition).
Researchers at Berkeley Lab have developed a new materials recipe for a battery-like hydrogen fuel cell that shields the nanocrystals from oxygen, moisture and contaminants while pushing its performance forward in key areas.
Methane and nitrous oxide emissions that result from human activity make the terrestrial biosphere, which includes all land-based ecosystems, a net contributor of greenhouse gas emissions. Agricultural, waste management and other practices have driven the transformation of the terrestrial biosphere, according to new research.
Terrestrial biosphere is contributing to climate change because of human activities including agriculture.
An international team that includes NIH-funded researchers at Stanford University has developed a therapeutic compound that is effective in inhibiting Plasmodium falciparum, one of five species of parasite that infects people with malaria, and the strain which causes the highest number of malaria deaths.
University of Virginia scientists have demonstrated that neurons in the brain that have been supplemented with a synthetic gene can be remotely manipulated by a magnetic field. The finding has implications for possible future treatment of a range of neurological diseases, such as schizophrenia and Parkinson’s disease.
Stanford scientists have discovered a novel way to make plastic from carbon dioxide (CO2) and inedible plant material, such as agricultural waste and grasses. Researchers say the new technology could provide a low-carbon alternative to plastic bottles and other items currently made from petroleum.
Processing food before eating likely played key role in human evolution, study finds.
Processing food before eating likely played key role in human evolution, study finds.
Findings may lead to new treatment strategies for several important bacterial infections.
Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.
One of the most critical questions surrounding climate change is how it might affect the food supply for a growing global population. A new study by researchers from Brown and Tufts universities suggests that researchers have been overlooking how two key human responses to climate -- how much land people choose to farm, and the number of crops they plant -- will impact food production in the future.
One of the most critical questions surrounding climate change is how it might affect the food supply for a growing global population. A new study by researchers from Brown and Tufts universities suggests that researchers have been overlooking how two key human responses to climate -- how much land people choose to farm, and the number of crops they plant -- will impact food production in the future.
A study led by the University of Tennessee and the Department of Energy’s Oak Ridge National Laboratory could soon pay dividends in the development of materials with energy-related applications.
A new study of gut bacteria in premature infants reveals the vast scope of the problem of antibiotic resistance and gives new insight into the extreme vulnerability of these young patients, according to researchers at Washington University School of Medicine in St. Louis.
New research in Nature Communications sheds light on what happens when a supervolcano erupts. The study combines recent lab tests with vintage field data — some of it captured in colorful Kodachrome slides — to provide insight on how rivers of hot ash and gas travel huge distances in supereruptions.
Last week, astronomers in another Nature paper indicated the discovery of the 17th FRB, reporting a radio “afterglow” of a new FRB, which is like a mushroom cloud following a huge explosion, says Shami Chatterjee, a Cornell senior researcher. “In our paper, we’re showing that our FRB can’t have an explosive origin. So, either there’s an odd coincidence, or maybe there are different types of FRBs. Either way, it seems we’ve broken this enigmatic phenomenon wide open.”
A team has solved the structure of a key protein in HKU1, a coronavirus identified in Hong Kong in 2005 and highly related to SARS and MERS. They believe their findings will guide future treatments for this family of viruses.
Over the past decade, studies have found that obesity and eating a high-fat, high-calorie diet are significant risk factors for many types of cancer. Now, a new study from Whitehead Institute and MIT’s Koch Institute for Integrative Cancer Research reveals how a high-fat diet makes the cells of the intestinal lining more likely to become cancerous.
Metastatic prostate cancer, where better therapeutic strategies are desperately needed, appears to be tailor-made for precision oncology, according to a new study by researchers at Fred Hutchinson Cancer Research Center in Seattle. They found that a single metastasis within an individual patient can provide consistent molecular information to help guide therapy in metastatic prostate cancer.
Different groups of neurons program biological clocks to orchestrate our behaviors by sending messages in a unidirectional manner downstream, a team of biologists has found.
Scientists at Berkeley Lab have developed a new imaging technique, tested on samples of nanoscale gold and carbon, that greatly improves images of light elements using fewer electrons. The technique can reveal structural details for materials that would be invisible to some traditional methods.
Columbia University scientists have developed a new optical technique to study how information is transmitted in the brains of mice. Using this method, they found that only a small portion of synapses—the connections between cells that control brain activity—may be active at any given time.
Just as the single-crystal silicon wafer forever changed the nature of communication 60 years ago, a group of Cornell researchers is hoping its work with quantum dot solids – crystals made out of crystals – can help usher in a new era in electronics.
Examination of shifting fish stocks illustrates potential net loss in global wealth.
Examination of shifting fish stocks illustrates potential net loss in global wealth.
The relationship between our future carbon dioxide emissions and future climate change depends strongly on the capacity of the ocean-carbon sink. That is a question climate scientists have so far been unable to answer. In a new paper, a research team headed by Galen McKinley, professor in the University of Wisconsin-Madison Department of Atmospheric and Oceanic Sciences, describes the best modeling approach to date for arriving at an answer to this and other crucial climate questions
For the first time, scientists at The Ohio State University have engineered new calcium receptors for the heart to tune the strength of the heartbeat in an animal model.
Two Virginia Tech researchers have discovered a way to maximize the amount of electricity that can be generated from the wastewater we flush down the toilet.
A team of scientists from Singapore and France has revealed the underlying mechanism for the formation and growth of a fundamental type of tissue – epithelial tubes. Defects in the architecture of epithelial tubes lead to diseases such as cholestasis, atherosclerosis and polycystic kidney disease. The research findings contribute towards a deeper understanding of the principles that underline epithelial tube formation, and offer opportunities for developing better therapies for such diseases. The study suggests that the shape and size of some types of epithelial tubes are governed by the mechanical forces that arise from the interaction of cells with the supportive extracellular matrix that surrounds them.
A team of researchers has created a way to quickly and remotely evaluate fluid flow in subsurface fractures that could impact aquifers, oil and gas extraction, sequestration of greenhouse gases or nuclear waste and remediation of leaked contaminants.
The research of two Montana State University microbiologists into how bacteria fend off attacks from viruses is included in a new paper published in the scientific journal Nature.
Ever since it was realized that asteroid and comet impacts are a real and present danger to the survival of life on Earth, it was thought that most of those objects end their existence in a dramatic final plunge into the Sun. A new study published on Thursday in the journal Nature finds instead that most of those objects are destroyed in a drawn out, long hot fizzle, much farther from the Sun than previously thought. This surprising new discovery explains several puzzling observations that have been reported in recent years.
Researchers say a fully sequenced Z. marina genome is a valuable resource that can advance research in a variety of areas. It could be used to study how marine ecosystems adapt under climate warming or to unravel the mechanisms of salt tolerance that assist in the breeding of crop plants.
Researchers at the University of Georgia, working with the International Peanut Genome Initiative, have discovered that a wild plant from Bolivia is a “living relic” of the prehistoric origins of the cultivated peanut species.
Tough emission controls have dramatically reduced the amount of toxic sulfate particles in air, but at least in the Southeast United States, they haven't reduced the acidity of the health-threatening particles.
Scientists at the University of East Anglia are getting closer to solving the problem of antibiotic resistance.
Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016 in Nature Microbiology, identifies a new mechanism for controlling HIV replication and its interaction with the host immune system.
Scientists from The Scripps Research Institute have identified a molecule that appears to be a cause of autoimmune diseases such as lupus. Elevated levels of the molecule allow self-reactive immune cells to escape into the blood stream and attack the body’s own tissues.
Fish, flies & bears, oh my! Research breakthrough gives genetic proof of how differences in (very different) animals develop.
University of Colorado Boulder researchers have demonstrated the use of the world’s first ultrafast optical microscope, allowing them to probe and visualize matter at the atomic level with mind-bending speed.
Researchers at the University of Chicago and the University of Konstanz have demonstrated the ability to generate a quantum logic operation, or rotation of the qubit, that is intrinsically resilient to noise as well as to variations in the strength or duration of the control.
In the first study of intravital microscopy in humans, Roswell Park scientists report that this approach for visualizing tumor blood vessels in real time during surgery is not only feasible, but that it revealed unexpected findings about the vasculature of human tumors.
A new study led by scientists at The Scripps Research Institute (TSRI) and the J. Craig Venter Institute (JCVI) shows that the act of creating pluripotent stem cells for clinical use is unlikely to pass on cancer-causing mutations to patients.
We all know that tying a knot in our everyday life involves a defined order of crossing ends of the rope. But how do we tie a molecule into a knot? Researchers report rules to define the order of crossing ends of the DNA chain to obtain rapidly self-tying highly knotted nanostructures.
For women with the most common type of breast cancer, a new way to analyze magnetic resonance images (MRI) data appears to reliably distinguish between patients who would need only hormonal treatment and those who also need chemotherapy. The analysis may provide women diagnosed with estrogen positive-receptor (ER-positive) breast cancer answers far faster than current tests and, due to its expected low cost, open the door to this kind of testing worldwide.
First genetic evidence of modern human DNA in a Neanderthal individual.
New research explores the impact of hunter-gatherers on north Pacific marine food webs and the behaviors that helped preserve their network of food sources. The findings hold implications for modern food webs.
UB geologist Jason Briner can discuss the implications of a new climate science paper by Stokes et al in Nature. Briner was not part of the research project.
The organs in our body may have a sexual identity of their own, new research suggests.
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