Experts at the GW, led by Gaby Moawad, MD, assistant professor of obstetrics and gynecology at the GW School of Medicine and Health Sciences, outlined some of the concerns and proposed solutions for choosing a surgeon in an article recently published in the Journal of Minimally Invasive Gynecology.
A UAB researcher is heading to Cameroon to study the effects and safety of antibiotics on pregnant women at risk of contracting malaria.
A study of more than 7,000 low-income, urban mothers enrolled in the Boston Birth Cohort found that fewer than 5 percent of them started folic acid supplementation and used it almost daily before pregnancy, a widely recommended public health measure designed to prevent potentially crippling birth defects.
Couples who eat more seafood tend to have sexual intercourse more often and get pregnant faster than other couples trying to conceive, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
A new study has identified several key factors in postmenopausal women that are associated with height loss, a common occurrence in this age group that is known to increase the risk for death and disease.
Os pesquisadores da Mayo Clinic descobriram que uma via de comunicação molecular – considerada ser deficiente em câncer – é um fator chave na determinação da eficácia do tratamento de câncer oncolítico do virus do sarampo em cânceres do cérebro agressivos e ovarianos. Esta descoberta permitiu que os pesquisadores desenvolvessem um algoritmo para prever a eficácia do tratamento em pacientes com câncer do cérebro e ovariano individuais. As constatações se encontram no Journal of the National Cancer Institute.
Women who are unable to quit smoking during their pregnancy may reduce the harm smoking does to their baby’s lungs by taking vitamin C, according to a new randomized, controlled trial presented at the ATS 2018 International Conference.
The health care systems in the United States and other industrialized countries have outgrown many of the childbirth-related injuries that are still very problematic in poor countries.
A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options. An international team of researchers led by the Perelman School of Medicine and the Basser Center for BRCA at the University of Pennsylvania reported their findings this week in JCO Precision Oncology.
Michigan State University researchers have found that when triclosan, a substance that reduces or prevents bacteria from growing, is combined with an antibiotic called tobramycin, it kills the cells that protect cystic fibrosis bacteria, known as Pseudomonas aeruginosa, by up to 99.9 percent.
From peer and patient education to addressing treatment side effects, nurses at Rutgers Cancer Institute of New Jersey researched a number of topics with an aim of enhancing the patient experience. Their findings are being presented at the Oncology Nursing Society’s Annual Congress.
Los investigadores de Mayo Clinic descubrieron que una vía de comunicación molecular, sobre la cual se creía que era defectuosa en el cáncer, desempeña un papel fundamental para determinar la eficacia del tratamiento con el virus del sarampión oncolítico en el cáncer de ovario y otros cánceres agresivos del cerebro.
Mayo Clinic researchers have discovered that a molecular communication pathway – thought to be defective in cancer – is a key player in determining the effectiveness of measles virus oncolytic cancer treatment in ovarian and aggressive brain cancers. This discovery enabled researchers to develop an algorithm to predict treatment effectiveness in individual patients. The findings appear in the Journal of the National Cancer Institute.
Emily and Len Blavatnik, whose significant philanthropic giving through the Blavatnik Family Foundation focuses on scientific research, higher education, and the arts, have made a $10 million gift to the Mount Sinai Health System.
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About 2 percent of pregnant women suffer a severe form of morning sickness known as hyperemesis gravidarum, or HG. The hallmark symptoms include rapid weight loss, malnutrition and dehydration due to unrelenting nausea and vomiting. It is the second-leading cause of hospitalization during pregnancy. Researchers are finally getting some answers on what causes it.
Recent studies in the journal Molecular & Cellular Proteomics have shed light on pathogenic mechanisms of the sexually-transmitted parasite Trichomonas vaginalis and the HIV-associated opportunistic lung fungus Aspergillus.
Researchers at the University at Buffalo Research Institute on Addictions have found that prenatal marijuana use also can have consequences on infants’ weight and can influence behavior problems, especially when combined with tobacco use.
South Sudanese women have among the highest fertility rates and maternal death rates in the world, yet cultural norms still frown upon contraceptives—even to make pregnancy and birth safer for women.
Becoming a mother was her greatest joy, but just days after giving birth to her daughter, Jessica Hitt’s mental state was severely affected by a rare genetic disorder. She became delirious, agitated, and hysterical. UT Southwestern researchers and physicians were able to quickly diagnose and treat the disease, and now she’s looking forward to expanding her family.
Alcohol use during pregnancy can lead to Fetal Alcohol Spectrum Disorders (FASDs), a range of effects that include lowered intelligence and developmental delays. Over 30 percent of the pregnancies in the United States are unplanned, with most women unaware of being pregnant until after the fourth week, and many not recognizing that they are pregnant until after that. However, the early weeks of pregnancy are critical for fetal development and susceptibility to the damaging effects of alcohol. While face-to-face interventions can significantly reduce risk for an alcohol-exposed pregnancy (AEP), this study, the Contraception and Alcohol Risk Reduction Internet Intervention (CARRII), examined an Internet-delivered intervention designed to reach more women at risk.
Few things are more daunting for first-time moms than the prospect of childbirth. However, nearly half of first-time moms (46 percent) said the pain they experienced with their first child was better than they expected, according to a nationwide survey commissioned by the American Society of Anesthesiologists (ASA) in honor of Mother’s Day.
Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center. The preclinical study suggests that mutations in ARID1a could be beneficial in predicting immunotherapy success.
Parents of twins and other multiple-birth children experience higher than average rates of depression, anxiety and other mental health issues, particularly during the first three months, according to a survey study in the May issue of Journal of Psychiatric Practice. The journal is published by Wolters Kluwer.
With the unexpected discovery of a panel of peptides from several proteins encoded by the parasite that causes malaria, new research underway at Seattle Children’s Research Institute could pave the way for a rapid screening test capable of diagnosing submicroscopic infections.
Women who eat less fruit and more fast food take longer to get pregnant and are less likely to conceive within a year, according to a study by researchers at the University of Adelaide’s Robinson Research Institute.
A joint UNLV and Oregon State University study found mothers who consumed their placenta passed on no harm to their newborn babies when compared to infants of mothers who did not consume their placenta.
Cedars-Sinai investigators are examining the risk factors associated with mental health issues experienced by many women after giving birth. According to the Centers for Disease Control and Prevention, 11 percent of women who give birth each year report symptoms of postpartum depression. Many experts believe the condition is even more prevalent, but the stigma associated with mental illness can prevent new mothers from seeking help.
A letter in the May 3, 2018, NEJM updates reports on the risks of exposure during pregnancy to a supplement, diethylstilbestrol (DES), that is linked to a rare cancer. DES-exposed patients with clear-cell adenocarcinoma had “increased mortality across their life span.”
Researchers recently identified a new “selfish” gene, wtf4, that encodes a toxin and an antitoxin in an effort to ensure the gene’s own transmission by killing off reproductive cells lacking the gene.
Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer – and they’ve also proven they have a way to see that feature using PET imaging.
A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes of infertility and spontaneous miscarriage. Infertility affects around 10 percent of the U.
Girls diagnosed with type 2 diabetes have a high frequency of menstrual irregularities, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub.
An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility. Now, researchers at Pennsylvania State University have found that zinc deficiency can negatively affect the early stages of egg development, reducing the ability of the egg cells to divide and be fertilized. This may affect fertility months in the future. The researchers will present their results at the American Physiological Society annual meeting at Experimental Biology 2018 in San Diego.
While some research suggests that midlife is a dissatisfying time for women, other studies show that women report feeling less stressed and enjoy a higher quality of life during this period.
Woman’s Fertility Preserved with Minimally Invasive Cervical Fibroid Embolization Procedure
Sara Biela and Chase Turner, graduate students in the lab of Wasana Sumanasekera at Sullivan University College of Pharmacy in Kentucky, will present new findings tied to hemp’s anti-cancer properties at the American Society for Biochemistry and Molecular Biology annual meeting during the 2018 Experimental Biology meeting to be held April 21-25 in San Diego.
While the health effects of breastfeeding are well-recognized and apply to both mothers and children, some mothers may not be able to produce a milk supply to meet the needs of their child. When infants require hospitalization in the immediate newborn period doing to being born preterm or having other health complications, human milk is a vital life-saving medical intervention.
Differences in the way women with obesity burn calories during pregnancy may be a contributor to long-term postpartum weight retention in black moms, according to researchers in Baton Rouge, La. Their new study shows that despite similar levels of food intake and activity levels—and a higher proportion of fat-free mass—obese black women burned fewer calories than their white counterparts. The findings, which suggest a need for more individualized pregnancy weight gain recommendations for obese women, will be presented today at the APS annual meeting at Experimental Biology 2018 in San Diego.
Dr. Giuliano Testa, principal investigator of the uterine transplant clinical trial, has been named to Time Magazine's ‘TIME 100’ – Time’s annual list of the 100 most influential people in the world.
Maintaining a stocked cart, with a full supply of the life-saving drug dantrolene, to treat malignant hyperthermia, a rare but potentially fatal adverse reaction to general anesthesia, may not be cost-beneficial in hospital maternity units where the incidence of the reaction is low.
The protein known as phosphatase and tensin homolog (PTEN) is frequently mutated or affected by cancer as tumors develop. Now a new study from the Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania shows PTEN may serve as a marker for whether a patient with BRCA 1-2 deficient ovarian cancer is likely to respond to checkpoint inhibitor therapy.
A Ludwig Cancer Research study has shown that an entirely new type of personalized cancer vaccine induces novel, potent and clinically effective immune responses in patients receiving a combination of standard therapies for recurrent, stage III and IV ovarian cancer.
A new type of cancer vaccine has yielded promising results in an initial clinical trial. The personalized vaccine is made from patients’ own immune cells, which are exposed to the contents of the patients’ tumor cells, and then injected into the patients to initiate a wider immune response. The trial, conducted in advanced ovarian cancer patients, was a pilot trial aimed primarily at determining safety and feasibility, but there were clear signs that it could be effective: About half of the vaccinated patients showed signs of anti-tumor T-cell responses, and those “responders” tended to live much longer without tumor progression than those who didn’t respond. The study is published today in Science Translational Medicine.
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