Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine’s biggest challenges: brain cancer. This month, they will launch a clinical trial using patients’ own modified T cells to fight advanced brain tumors.
Researchers have used an X-ray laser to record, in detail never possible before, the microscopic motion and effects of shock waves rippling across diamond. The technique, developed at the Department of Energy's SLAC National Accelerator Laboratory, allows scientists to precisely explore the complex physics driving massive star explosions, which are critical for understanding fusion energy, and to improve scientific models used to study these phenomena.
Monitoring men with very low- and low-risk prostate cancers using watchful waiting or active surveillance, called expectant management, is a useful approach for a large number of men with localized tumors and could spare them the debilitating side effects of aggressive treatments that are too often unnecessarily used in this patient population, a UCLA review of common practices in prostate cancer has found.
Texas Christian University and the University of North Texas Health Science Center have entered into a memorandum of understanding to create a new MD school in Fort Worth.
Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes — chemical modifications cells use to control which genes are turned on or off.
Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered to lack a key calcium channel in their heart cells, Johns Hopkins scientists appear to have cast a shadow of doubt on that theory. A report on their study is published online this week in Proceedings of the National Academy of Sciences.
Common extra heartbeats known as premature ventricular contractions (PVCs) may be a modifiable risk factor for congestive heart failure (CHF) and death, according to researchers at UC San Francisco.
The Association of American Cancer Institutes (AACI) Clinical Research Initiative (CRI) will convene its seventh annual meeting July 8-9 in Chicago. The meeting will focus on immunotherapies for cancer and their impact on cancer clinical trials.
Imagine a fleet of driverless taxis roaming your city, ready to pick you up and take you to your destination at a moment’s notice. While this may seem fantastical, it may be only a matter of time before it becomes reality. And according to a new study from Lawrence Berkeley National Laboratory, such a system would both be cost-effective and greatly reduce per-mile emissions of greenhouse gases.
Studying brain scans and cerebrospinal fluid of healthy adults, scientists have shown that changes in key biomarkers of Alzheimer's disease during midlife may help identify those who will develop dementia years later, according to new research.
New research suggests that a molecule commonly found “decorating” brain cells in higher animals, including humans, may affect brain structure. The study showed that small changes made in how sialic acid attaches to cell surfaces can cause damaged brain structure, poor motor skills, hyperactivity and learning difficulties in mice.
Researchers reveal how cells in the peripheral nervous system degrade myelin after nerve injury, a process that fails to occur in the central nervous system. The results could provide new targets for manipulating demyelination in injury and disease.
Other topics include memories and protein, physics and gas mileage, agriculture and food safety, vaccine for Dengue, retinoblastoma proteins in cancer progression, and more.
Over the same time period that multiple outbreaks of measles and whooping cough made headlines around the country, parents’ views on vaccines became more favorable.
When aluminum atoms bunch up, porous materials called zeolites lose their ability to convert oil to gasoline. An international team of scientists created the first 3-D atomic map of a zeolite in order to find out how to improve catalysts used to produce fuel, biofuel and other chemicals.
Sylvia Hernando became a Community Health Worker (CHW) because she wanted to help others. Hernando had been a stay-at-home mother and was looking to go back to school when she heard about the CHW certification program at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.
To protect consumers from foodborne illness, produce farmers should wait 24 hours after a rain or irrigating their fields to harvest crops,
Why does summer gas cost more (but get you better mileage?) Why does accelerating use more gas than driving at a steady speed? Argonne transportation engineer Steve Ciatti talks about the science behind gas mileage.
Researchers at the University of Adelaide have discovered a new method for culturing stem cells which sees the highly therapeutic cells grow faster and stronger.
A review article published on the journal Oncotarget focusing on RB role in apoptosis provides a comprehensive overview on the role of RB proteins in the coordinated control of cell decisions.
Stephen O’Rourke, professor of pharmaceutical sciences at North Dakota State University, Fargo, has received a $435,000 grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to conduct cardiovascular research.
Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.
A new study suggests that genes may not be to blame for the increased risk of heart disease some studies have shown in people with migraine, especially those with migraine with aura. The research is published during Headache/Migraine Awareness Month in the inaugural issue of the journal Neurology® Genetics, an open access, or free to the public, online-only, peer-reviewed journal from the American Academy of Neurology. Aura are sensations that come before the headache, often visual disturbances such as flashing lights.
MedStar Heart & Vascular Institute at MedStar Washington Hospital Center was the first hospital in the Washington metropolitan region to implant the newly approved WATCHMAN™ Device. The new device is designed to prevent stroke in high-risk patients with atrial fibrillation who are seeking an alternative to blood-thinning medication. Blood thinners are effective in reducing the risk of stroke for patients with A-fib, but many cannot tolerate these medications because of the risk of bleeding. The WATCHMAN device, which resembles a tiny umbrella, is used to close off a pouch on the left side of the heart, which is believed to be the source of the majority of stroke-causing blood clots.
Research from Eric Kandel’s lab has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time.
The first comprehensive analysis of the woolly mammoth genome reveals extensive genetic changes that allowed mammoths to adapt arctic life, including skin and hair development, insulin signaling, fat biology, and even traits such as small ears and short tails. A mammoth gene for temperature sensation was resurrected in the lab as a functional test.
Other topics include neurology, obesity, statins, and the risks of wearing high heels.
The "placebo effect" is often described as events that occur when patients show improvement from treatments that contain no active ingredients. A "Perspectives" article in the July 2 issue of The New England Journal of Medicine proposes that placebo effects be more broadly defined to reflect their role as a valuable component of medical care.
A new study showing the negative effects of prolonged high heel use confirms expert consensus on the footwear, according to a UNC Charlotte expert.
Researcher Bin Guo at North Dakota State University, Fargo, is receiving a four-year $1.35 million research project grant from the National Cancer Institute of the National Institutes of Health to develop a targeted treatment for colorectal cancer.
Light switches for neurons have made enormous contributions to brain research by giving investigators access to “on switches” for brain cells. But, finding “off switches” has been much more challenging. Addressing the challenge, biochemists in the Center for Membrane Biology at The University of Texas Health Science Center at Houston (UTHealth) discovered a new family of light-activated proteins that work as “off switches.”
The Wayne State University School of Medicine and Detroit Receiving Hospital of the Detroit Medical Center will serve as a site for a national study that will develop new guidelines for patients released from the emergency room after treatment for suspected acute heart failure symptoms.
Researchers from the Icahn School of Medicine at Mount Sinai have discovered that histones are steadily replaced in brain cells throughout life
In the first randomized trial to look at statin effects on behavior, researchers at the University of California, San Diego School of Medicine report that aggressive behavior typically declined among men placed on statins (compared to placebo), but typically increased among women placed on statins.
New research using data from the reputable Look AHEAD study suggests doctors may want to look at results from a patient’s first two months of intensive lifestyle intervention (ILI) to help predict his or her long-term success. These secondary analyses conducted by Unick and colleagues published in the July issue of Obesity, the scientific journal of The Obesity Society examined the association between initial weight loss (first two months of treatment) and long-term weight loss (eight years after initial treatment).
UT Southwestern Medical Center scientists collaborating with University of Michigan researchers have found a previously unidentified mechanism that helps explain why stem cells undergo self-renewing divisions but their offspring do not.
Other topics include; do x-rays really cause cancer? And more.
Researchers at the George Washington University (GW), led by Michael S. Irwig, M.D., found that men referred for tertiary care for borderline testosterone levels had much higher rates of depression and depressive symptoms than those of the general population.
In the first study of its kind, UCLA and United Kingdom researchers found that neurons in a specific brain region play a key role in rapidly forming memories about every day events, a finding that may result in a better understanding of memory loss and new methods to fight it in Alzheimer’s and other neurological diseases.
Using clinical data collected over the past decade through a U.S. cancer registry, researchers at the University of California, San Diego School of Medicine demonstrated that significant strides have been made in improving the survival of adult patients with low-grade gliomas, a slow-growing yet deadly form of primary brain cancer.
Despite concerns that use of antipsychotic medications in treating young people has increased, use actually declined between 2006 and 2010 for children ages 12 and under, and increased for adolescents and young adults.
The FDA has given food companies three years to remove artificial trans fat from their products, but a Kansas State University food scientist explains most companies have already made the adjustment.
Although being overweight with a high body-mass index (BMI) has long been associated with a higher risk for colorectal cancer, thinner patients might not fare as well after treatment for advanced cancer, according to a new study from Duke Medicine.
Falling gas prices can shorten the time it takes a house to sell and can increase the selling price, according to results from an ongoing longitudinal study by Florida Atlantic University and Longwood University faculty.
Regular, structured extracurricular sports seem to help kids develop the discipline they need in order to engage effectively in the classroom, according to a new study led by Linda Pagani of the University of Montreal and its affiliated CHU Sainte-Justine children’s hospital.
A study of nearly 1,000 teens found that obese adolescents were significantly less likely to use contraception than normal weight peers, putting them at higher risk of unintended pregnancy.
Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates.
Studies purporting to show that radiation from X-rays, CT scans and other medical imaging causes cancer have been widely reported. But such studies have serious flaws, including their reliance on an unproven statistical model, according to a recent article in the journal Technology in Cancer Research & Treatment.
Michael Allen Pulsipher, MD, will join the Children’s Center for Cancer and Blood Diseases and the Division of Hematology, Oncology and Blood and Marrow Transplantation at Children’s Hospital Los Angeles as head of the Section of Blood and Marrow Transplantation (BMT) and as BMT clinical research chair, effective July 1, 2015. In addition, Pulsipher will be a professor of Pediatrics at the Keck School of Medicine of the University of Southern California (USC) and a Member of the USC Norris Comprehensive Cancer Center.
Roswell Park Cancer Institute will provide clinical consultations and training for staff at Lakeshore Cancer Center, Lagos, Nigeria, through an affiliation announced today.
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