A new analysis by a researcher at Beth Israel Deaconess Medical Center (BIDMC) finds a link between large gatherings of unvaccinated county residents – both students and non-students – and an increase in COVID-19 infections in the university’s community.
Lithium is a common medication prescribed to patients with psychiatric disorders, namely bipolar disorder, schizophrenia, and depression. It is used as a mood stabilizer and lessens the intensity of manic episodes, with particular benefit in reducing suicidality. While highly effective, the drug requires routine blood monitoring, which can be uncomfortable, expensive, and inconvenient for patients who must travel to clinical labs for frequent blood testing.
A booster dose of the mRNA-1273 COVID-19 vaccine given to rhesus macaques about six months after their primary vaccine series significantly increased levels of neutralizing antibodies against all known SARS-CoV-2 variants of concern, according to a new study from National Institutes of Health scientists and colleagues.
Using a novel technology, the lab of Michael Vahey at the McKelvey School of Engineering uncovered shape-shifting properties of a common respiratory virus.
Vaccination is over 90 per cent effective at preventing deaths from the Delta variant of Covid-19, according to the first country-level data on mortality.
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded $17.5 million over three years to the Duke Human Vaccine Institute to develop a vaccine that protects against multiple types of coronaviruses and viral variants.
Lawrence Livermore National Laboratory has joined the international Human Vaccines Project, bringing Lab expertise and computing resources to the consortium to aid development of a universal coronavirus vaccine and improve understanding of immune response.
In pregnant women who tested positive for SARS-CoV-2, the virus that causes COVID-19, male placentas demonstrated significantly higher levels of certain genes and proteins associated with increased immune activation compared with female placentas, according to a new study published in Science Translational Medicine.
Future vaccine delivery may rely on everyday items like BBQ lighters and microneedles, thanks to the ingenuity of a team of Georgia Institute of Technology and Emory University researchers.
New research from the University of Notre Dame suggests that experts from varying fields need to work together to overcome the public health crisis and that science can benefit by using marketing strategies with vaccine holdouts, much like brands do with customers.
A team of research experts from the COVID-19 Prevention Network (CoVPN), headquartered at Fred Hutchinson Cancer Research Center, has demonstrated that through robust community engagement, equitable inclusion in vaccine clinical trials can make a powerful impact in the health of underrepresented communities.
While most of the COVID-19 vaccines are designed as a two-dose regimen, some countries have prioritized vaccinating as many people as possible with a single dose before giving out an additional dose. In the journal Chaos, researchers illustrate the conditions under which a "prime first" vaccine campaign is most effective at stopping the spread of the COVID-19 virus. The team found the vaccine waning rate to be a critically important factor in the decision.
Nonpharmaceutical interventions, such as isolation, quarantines, and lockdowns, have been implemented in an effort to contain the pandemic, but these are often disruptive and costly. In Chaos, researchers identify new and sustainable interventions to contain outbreaks while minimizing the economic and social costs. They built a data-driven mobility model to simulate COVID-19 spreading in Hong Kong, by combining synthetic population, human behavior patterns, and a viral transmission model, and found that by controlling a small percentage of grids, the virus could be largely contained.
The members of the Critical Care Societies Collaborative, which includes the American Association of Critical-Care Nurses, American College of Chest Physicians, American Thoracic Society, and Society of Critical Care Medicine, strongly urge individuals to get vaccinated against the COVID-19 virus and to receive their influenza (flu) immunizations for the upcoming flu season.
People who had received a first dose of the Oxford-AstraZeneca COVID-19 vaccine and received an mRNA vaccine for their second dose had a lower risk of infection compared to people who had received both doses of the Oxford-AstraZeneca vaccine.
Patients with the blood cancer multiple myeloma often mount a poor antibody response to COVID-19 vaccines. Mount Sinai researchers have now discovered that these patients also have a weak response from a different part of the immune system, known as T cells. Their discovery was published in a research letter in Cancer Cell in October.
“Twindemic” is a term that has not yet been in the headlines but is likely to become part of our lexicon as the summer progresses.
An analytical study examined levels of vaccine efficacy and mitigation strategies. If 100 percent were vaccinated with 90 percent vaccine efficacy, testing and quarantine did not substantially reduce infections. At 75 percent efficacy, weekly testing substantially reduced the number of infections; at 50 percent, testing and quarantine markedly reduced infections. At 50 to 75 percent efficacy, testing reduced infections up to 93.6 percent. Quarantining for 10 days only modestly reduced infections until vaccine efficacy dropped to 50 percent. Findings suggest that testing and isolating positive cases may remain important mitigation strategies for universities even with 100 percent of students vaccinated.
In a paper published in the New England Journal of Medicine, a team of experts at Beth Israel Deaconess Medical Center compared immune responses induced by the three COVID-19 vaccines over an eight-month follow-up period.
Patients who have cardiovascular disease are at increased risk of serious complications from the flu, according to a new study by Houston Methodist physician researchers published in the Journal of the American Heart Association. The study found that not only are traditional flu-related outcomes worse among some patients with CVD, but infection in those patients also is associated with an increased risk of cardiovascular events and both CV-related mortality and mortality from all causes.
A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study.
State leaders in West Virginia called upon WVU’s School of Public Health to assist with vaccination communications targeting minority communities and other key demographics.
The Bloomberg School and the Pulitzer Center are co-hosting a free online event today, Thursday, October 14, at 1 p.m., EDT, with leading public health and communications experts to discuss ways to better reach vaccine-hesitant young adults during the pandemic.
Dr. Erika Werner of Tufts University School of Medicine and Tufts Medical Center on why pregnant women are more vulnerable to the virus, why she recommends the vaccine, and what she hears from her patients.
Ian Cheeseman, Ph.D., and his collaborators can now sequence the genomes of individual parasites found in the blood of infected patients -- even when the infection burden is very low, which can occur during asymptomatic infections. Gaining this incredibly detailed view is expected to help develop more effective treatments, vaccines or therapies.
An engineering researcher at the University of Oklahoma is part of a National Science Foundation project addressing the logistical challenges of maintaining cryogenic temperatures for Messenger RNA (mRNA) molecules, a molecule that allows human cells to recognize and protect against infectious diseases. Dimitrios Papavassiliou, Ph.D., in the Gallogly College of Engineering, is investigating Distributed Ribonucleic Acid Manufacturing – DReAM – that would create a manufacturing technique to produce mRNA sequences on demand and on-site. The research is funded by the NSF through a four-year, $2 million grant from its Emerging Frontiers in Research and Innovation program.
Scientists at Washington University School of Medicine in St. Louis have developed a chemical compound that interferes with a key feature of many viruses that allows the viruses to invade human cells. The compound, called MM3122, was studied in cells and mice and holds promise as a new way to prevent infection or reduce the severity of COVID-19 if given early in the course of an infection, according to the researchers.
A new study, which finds an increased risk of poorer outcomes for the new-borns and symptomatic women with COVID-19, adds further weight to the argument for pregnant women to be vaccinated for the virus.
The Bloomberg School and the Pulitzer Center are co-hosting a free online event on October 14, at 1 p.m., EDT, with leading public health and communications experts to discuss ways to better reach vaccine-hesitant young adults during the pandemic.
Study may have implications for other vaccinations, including COVID-19 vaccine.
Cedars-Sinai took a firm stance on vaccination this week, releasing a multimedia campaign in support of COVID-19 vaccines and the scientists who developed them.
Researchers in Japan have developed a vaccination strategy in mice that promotes the production of antibodies that can neutralize not only SARS-CoV-2 but a broad range of other coronaviruses as well. If successfully translated to humans, the approach, to be published October 8 in the Journal of Experimental Medicine, could lead to the development of a next-generation vaccine capable of preventing future coronavirus pandemics.
Stringent lockdown measures imposed in the spring of 2020 led to a dramatic drop in vaccinations among both children and adults, according to a new study led by Children’s Hospital of Philadelphia (CHOP).
A majority of Chicago parents feel that schools and employers should be able to require students and employees to be vaccinated for COVID-19, respectively, according to results of the latest survey by Ann & Robert H. Lurie Children’s Hospital of Chicago.
Health care personnel who received a two-dose regimen of Pfizer–BioNTech vaccine had an 89% lower risk for symptomatic illness than those who were unvaccinated. For those who received the two-dose regimen of the Moderna vaccine, the risk was reduced by 96%.
A meme widely shared on Facebook shows a picture of Bill Gates holding a needle with his face painted like the supervillain “The Joker” and says, “Do you honestly believe that in 70 years of research and development we have a 40% effective flu shot but in 10 months a 95% effective Rona shot?” Comparing the efficacy of the vaccines suggest they both inoculate patients from the same virus. The viruses are different, and comparing the efficacy of the vaccines is misleading.
Two doses of Pfizer-BioNTech (BNT162b2) are 90% effective against COVID-19 hospitalizations for all variants, including delta, for at least six months, confirms a new study from Kaiser Permanente and Pfizer published in The Lancet
The long-acting antibody combination was originally developed at Vanderbilt University Medical Center to protect against COVID-19.
A second dose of the COVID-19 vaccine should be offered to individuals infected with the virus shortly after receiving the first dose, according to findings recently published by the Azrieli Faculty of Medicine of Bar-Ilan University and Ziv Medical Center.
New research focused on Texas nurses has found predictors of a lack of intention to be vaccinated against COVID-19 includes previous COVID-19 infection, unfavorable vaccine attitudes, and concerns about vaccine safety. Researchers from Cizik School of Nursing at The University of Texas Health Science Center at Houston (UTHealth Houston) published the results in the October 2021 issue of the Texas Journal of Public Health.
Chemical engineer Catherine Fromen has been awarded a $2 million federal grant to study how medicines overcome mucosal barriers in the body, such as in the lungs or the gut. “Think about vaccines … if we can better understand how to deliver medicines to treat cells directly at the site, it will be even better than getting a shot in the arm,” Fromen said.
UNLV scientists are partnering with 20 other states to keep watch for flu strains that are cropping up in wastewater in communities across the country to better target future influenza vaccines and make them more effective.
The COVID-19 pandemic has been an especially stressful time for cancer patients undergoing chemotherapy, which attacks not only the cancer, but also the immune cells needed to defend the body from infections.
A University of California, Irvine-led study, based on interviews of 50 Latina and Vietnamese women, revealed that this population turns to many sources for information about the HPV vaccine – from online and social media to school health classes, mothers, and doctors.
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