Researchers at the University of Warwick have worked with Coventry-based Medherant, a Warwick spinout company, to produce and patent the World’s first ever ibuprofen patch delivering the drug directly through skin to exactly where it is needed at a consistent dose rate.
Scientists at Seattle Children’s Research Institute have found a way to rapidly suppress epilepsy in mouse models by manipulating a known genetic pathway using a cancer drug currently in human clinical trials for the treatment of brain and breast cancer.
New hope now exists for patients with advanced kidney cancer. Yesterday, the FDA approved the immunotherapy drug nivolumab (Opdivo®, Bristol-Myers Squibb) to treat metastatic renal cell carcinoma (RCC)—the most common form of kidney cancer—that has failed to respond to a previous treatment. This breakthrough can be traced all the way back to the research of scientists funded by the Cancer Research Institute (CRI).
When associate professor of pharmacy practice Tadd Hellwig of South Dakota State University and three pharmacy colleagues at the Sanford USD Medical Center noticed that some hospital patients given two common antibiotics developed kidney failure, they decided to take a closer look. Their study led to closer monitoring of patients receiving vancomycin and piperacillin-tazobactam due to an increased risk of kidney damage.
A sick person is obviously willing to pay for a good medical treatment, but economists have found that healthy people are potentially a much broader, if largely overlooked, market for medical innovations.
A discovery by Cornell University bioengineers is shedding new light on the controversy surrounding a common treatment for osteoarthritis that has divided the medical community over its effectiveness.
Article Body 2010U.S. pharmaceutical giant Pfizer announced Nov. 23 a record-breaking $160 billion merger with Irish firm Allergan, the biggest merger to-date involving the controversial strategy of tax inversion. The move marks the beginning of the end of the ability to stop corporate tax inversions under current tax rules, said an expert on international tax law at Washington University in St.
Kids and teens who take medications like Ritalin to treat attention-deficit hyperactivity disorder are twice as likely to be physically or emotionally bullied by peers than those who don't have ADHD, a new University of Michigan study found.
On Tuesday, the American Medical Association called a ban on direct-to-consumer prescription drugs ads. They say the ads drive up the demand for more expensive treatments. Experts Need for this topic.
The medication sildenafil – sold under Viagra and other trade names – improves insulin sensitivity in individuals with prediabetes and also reduces a biological marker that signals heightened risk of kidney and heart disease, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
A URI researcher is developing a nicotine vaccine and accompanying drug delivery system that he believes could lead to one of the most effective methods of combating cigarette smoking and other tobacco use.
Cetuximab, marketed as Erbitux®, is one of the key therapies for metastatic colorectal cancer. Yet the cancer still returns in some patients, shortening overall survival.
Johns Hopkins Children’s Center specialists report they have successfully treated and put in remission a 2-year-old, now age 5, with a highly virulent form of tuberculosis known as XDR TB, or extensively drug-resistant TB.
A new consumer infographic on SafeMedication.com reveals the five medication questions patients should always ask their pharmacist.
Medical marijuana needs to be studied like any other drug. No one is opposed to the active ingredients in it, but we need to have some data. That is what we would expect from any other drug, Bednarczyk says.
Principal Investigator Takes Questions and Demonstrates Procedure with Video and Animation via Virtual Press Conference Tuesday, November 10th at 1:00 p.m. ET
Right now, in any US hospital, about half of the patients have a prescription for an acid-reducing drug to reduce heartburn or prevent bleeding in their stomach and gut. But that well-intentioned drug may actually boost their risk of dying during their hospital stay – by opening them up to infections that pose more risk than bleeding would.
Scientists at the University of North Carolina School of Medicine (UNC) and University of California, San Francisco (UCSF) have created a general tool to probe the activity of these orphan receptors, illuminating their roles in behavior and making them accessible for drug discovery
Heart failure patients with preserved ejection fraction (HFpEF) — where the heart becomes stiff and cannot relax or fill properly — did not have increased exercise tolerance after taking isosorbide mononitrate, compared to a placebo.
For patients undergoing plastic surgery procedures, there's no consistent evidence that taking antidepressants increases the risk of bleeding, breast cancer, or other adverse outcomes, concludes a research review in the November issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Proton pump inhibitors (PPIs), a class of drugs used to treat acid reflux and other acid-related gastrointestinal conditions, may increase the risk for developing chronic kidney disease (CKD). Two new studies that reached similar conclusions on the increased CKD risk associated with PPI use will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
A new study from the University of Michigan Comprehensive Cancer Center reveals molecular changes within a tumor that are preventing immunotherapy drugs from killing off the cancer.
Researchers discover way to bypass faculty cell signaling that leads to muscle damage in Duchene muscular dystrophy.
Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments. Tamoxifen treatment in mice also enhances clearance of the antibiotic-resistant bacterial pathogen MRSA and reduces mortality.
An experimental, biologic treatment, brodalumab, achieved 100 percent reduction in psoriasis symptoms in twice as many patients as a second, commonly used treatment, according to the results of a multicenter clinical trial led by Mount Sinai researchers and published online today in the New England Journal of Medicine.
When it comes to treating depression, how well a person responds to a fake medicine may determine how well they’ll respond to a real one, a new study shows. Those who can muster their brain’s own chemical forces against depression have a head start in overcoming symptoms with help from medication.
In a new study, scientists from the Florida campus of The Scripps Research Institute (TSRI) describe a class of compounds with the potential to stop chronic itch without the adverse side effects normally associated with medicating the condition.
researchers from the University of Zurich, Switzerland have made a breakthrough by obtaining the first nanometer (one billionth of a meter) resolved image of individual tobacco mosaic virions, a rod-shaped RNA virus that infects a wide range of plants, especially tobacco. The work demonstrates the potential of low-energy electron holography as a non-destructive, single-particle imaging technique for structural biology. The researchers describe their work in a paper published this week on the cover of the journal Applied Physics Letters, from AIP Publishing.
More than half of older adults with clinical depression don’t get better when treated with an antidepressant. But results from a multicenter clinical trial that included Washington University School of Medicine in St. Louis indicates that adding a second drug — an antipsychotic medication — to the treatment regimen helps many of those patients.
In an international Phase III randomized study, everolimus, an inhibitor of the mammalian target of rapamycin (mTOR), has shown to dramatically improve progression-free survival for patients with advanced, nonfunctional neuroendocrine tumors (NET) of the lung and gastrointestinal tract.
For the first time, an immune checkpoint inhibitor has been proven to increase survival among patients with advanced renal cell carcinoma (RCC), a patient population for whom treatment options are currently limited.
A new study has shown that for certain cancer drugs, participants in clinical trials are often not representative of the patients that ultimately take the drugs, raising questions about the direct applicability of trial data.
A University of Adelaide led study has found that a psychiatric drug claimed to be a safe and effective treatment for depression in adolescents is actually ineffective and associated with serious side effects.
A novel, one-step method to treat ulcerative colitis with an oral drug consisting of microparticles and natural herbal molecules that target the colon shows promise as an effective therapy, according to researchers from the Institute for Biomedical Sciences at Georgia State University and Southwest University in China.
Drugs commonly used to treat high blood pressure, and prevent heart attacks and strokes, are associated with significantly worse cardiovascular outcomes in hypertensive African Americans compared to whites, according to a new comparative effectiveness research study led by researchers in the Department of Population Health at NYU Langone Medical Center, published in the Journal of the American College of Cardiology.
Researchers at the National University of Singapore (NUS) have developed a technique to observe, in real time, how individual blood components interact and modify advanced nanoparticle therapeutics.
A scientist at the University of Virginia School of Medicine is rescuing vast amounts of humanity’s knowledge of the submicroscopic world from potential oblivion, making it more accessible than ever before and doing so on a budget many thought impossible.
Many of us are guilty of neglecting our medicine cabinet – specifically, our prescriptions. Sometimes we feel the need to hang onto them, perhaps because they were costly or "just in case." But doing so may cause more harm than good.
Researchers from the Icahn School of Medicine at Mount Sinai and Princeton University have designed a new online tool that predicts the role of key proteins and genes in diseases of the human immune system.
Agent shows efficacy in inhibiting inflammation and preventing or delaying uterine contractions and premature delivery in murine models – without adversely affecting the fetus or the mother. This discovery is a giant step towards preventing prematurity, the world's leading cause of infant death.
Click to view today's top stories.
A multinational team of physicians and scientists from City of Hope, the San Francisco Bay area and Europe recently reported success of a phase II clinical trial of a novel drug against essential thrombocythemia (ET), one of three myeloproliferative neoplasms (MPNs).
Scientists at Queen’s University Belfast are developing a potential revolutionary new treatment for Sepsis and Acute Respiratory Distress Syndrome (ARDS), which are among the leading causes of death in hospitalised patients in the UK.
Scientists have discovered that wild blueberry extract could help prevent dental plaque formation.
Upsetting the balance between protein synthesis, misfolding, and degradation drives cancer and neurodegeneration. Recent cancer treatments take advantage of this knowledge with a class of drugs that block protein degradation, known as proteasome inhibitors. Widespread resistance to these drugs limits their success, but Whitehead researchers have discovered a potential Achilles heel in resistance. With such understandings researchers may be able to target malignancy broadly, and more effectively.
Scientists from The Scripps Research Institute Florida campus have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output, findings that could aid future drug design.
Commonly used antidepressant drugs change levels of a key signaling protein in the brain region that processes both pain and mood, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published August 24 in the Proceedings of the National Academy of Sciences (PNAS).
A recently-published study found that while internal bleeding may be uncommon as a result of taking blood thinners such as Xarelto® (rivaroxaban) and Eliquis® (apixaban), the normal coagulation tests physicians use to check for the side effect of bleeding may not be reliable.
In experiments with 500,000 genetically engineered zebrafish embryos, Johns Hopkins scientists report they have developed a potentially better and more accurate way to screen for useful drugs, and they have used it to identify 24 drug candidates that increase the number of insulin-producing cells in the pancreas.
Among patients with active cancer and acute symptomatic venous thromboembolism (VTE; blood clots in the deep veins), the use of the low molecular-weight heparin tinzaparin daily for 6 months compared with warfarin did not significantly reduce recurrent VTE and was not associated with reductions in overall death or major bleeding, but was associated with a lower rate of clinically relevant nonmajor bleeding, according to a study in the August 18 issue of JAMA.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right