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Released: 4-Mar-2022 12:00 PM EST
Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review
Stem Cell Research & Therapy

Graft-versus-host disease (GVHD) is a common fatal complication of hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment option. However, there are currently no second-line tre...

Newswise: Making Diversity, Equity, Inclusion Integral Part of Physics Education
Released: 4-Mar-2022 11:05 AM EST
Making Diversity, Equity, Inclusion Integral Part of Physics Education
American Institute of Physics (AIP)

While many physics instructors are beginning to incorporate lessons on diversity, equity, and inclusion in the classroom, it can often feel like an add-on rather than an integral component of becoming a physicist. In The Physics Teacher, scientists are helping to change this by presenting discussions and activities on DEI as a fundamental and essential part of physics training. The team created two approaches for DEI curriculum, replacing a question on a weekly homework assignment with a reflection essay on a topic important to physicists and including activities and discussions during a two-day unit on representation.

3-Mar-2022 12:05 PM EST
Could a Community-Based Approach to Genetic Testing Help African Americans Reduce Risks of Chronic Kidney Disease?
Mount Sinai Health System

In 2010, scientists discovered that African Americans who are born with certain variants of a gene called apolipoprotein L1 (APOL1) have a higher-than-average risk for experiencing chronic kidney disease (CKD). Now, in a new study of African Americans with hypertension, researchers at the Icahn School of Medicine at Mount Sinai find that a community-based approach to reporting APOL1 genetic test results back to individuals may have beneficial effects.

2-Mar-2022 1:35 PM EST
Combination treatment is effective for treating smokers who drink heavily
University of Chicago Medical Center

A study on smokers who drink heavily finds that a combination treatment of the drug varenicline and nicotine replacement therapy is more effective for smoking cessation, and that efforts to quit smoking can indirectly lead to reduced drinking rates.

Released: 4-Mar-2022 10:05 AM EST
Microneedle approach to address peanut allergy shows promise in mice
Michigan Medicine - University of Michigan

Mice that received treatments with peanut-coated microneedles had significant increased rates of desensitization to peanut allergy compared with epicutaneous immunotherapy (EPIT), a new study found. The microneedle treatment success was achieved despite applying a dose of peanut protein 10-times lower than the dose delivered by EPIT. Researchers say the findings demonstrate the potential for peanut microneedles to improve food allergen immunotherapy through the skin.

3-Mar-2022 4:00 PM EST
New Neiman HPI Study Found 18% Increase In Radiology-Employed Non-Physician Providers
Harvey L. Neiman Health Policy Institute

A new Harvey L. Neiman Health Policy Institute study found that between 2017 and 2019 the number of non-physician providers (NPPs, which includes nurse practitioners and physician assistants) employed by radiology-only practices increased 18%. This increase was associated with more NPPs employed per practice as well as an 11% increase in the number of practices employing them. This Journal of the American College of Radiology study was based on Centers for Medicare and Medicaid Services databases of doctors and clinicians who participated in Medicare.

Newswise: Research from Georgia Tech and Emory University Leads to FDA Breakthrough Designation for New PTSD Treatment
Released: 4-Mar-2022 8:05 AM EST
Research from Georgia Tech and Emory University Leads to FDA Breakthrough Designation for New PTSD Treatment
Georgia Institute of Technology

A pilot study from Georgia Tech researcher Omer Inan and Emory University psychiatrist Douglas Bremner opens the door to a hopeful new therapeutic alternative for people suffering from PTSD.

   
Released: 4-Mar-2022 8:05 AM EST
Younger age at first menstrual period linked to chronic pain in women, reports study in PAIN®
Wolters Kluwer Health: Lippincott

Women who were younger at the time of their first menstrual period (menarche) are more likely to report chronic pain in adulthood, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 4-Mar-2022 8:05 AM EST
New structure studies of a critical Nipah virus component may lead to vaccine, antibody treatments
Uniformed Services University of the Health Sciences (USU)

Researchers at the Uniformed Services University in collaboration with University of Washington, have recently uncovered new details about how Nipah and Hendra viruses infect cells and the immune responses that can block them, which could ultimately lead to the development of new tactics to prevent and treat these deadly illnesses.

Released: 4-Mar-2022 8:05 AM EST
Mindfulness Meditation Can Reduce Guilt, Leading to Unintended Negative Social Consequences
University of Washington

Mindfulness meditation is a stress-management practice with ancient lineage that cultivates nonjudgmental awareness of the present moment, often by directing attention to the physical sensations of breathing. Initially inspired by centuries-old Buddhist practices consisting of philosophies and meditations together, today a secular version of mindfulness — consisting of meditations alone — is becoming increasingly popular.

Released: 4-Mar-2022 8:05 AM EST
Facial transplant techniques may extend to other types of severe facial injuries
Wolters Kluwer Health: Lippincott

The composite tissue transfer techniques used and refined in face transplant surgery may also be used to perform microsurgical replantation – using the person's own tissues – in patients with other types of severe facial injuries, suggests a clinical report in The Journal of Craniofacial Surgery. The journal, under the guidance of Editor-in-Chief Mutaz B. Habal, MD, is published in the Lippincott portfolio by Wolters Kluwer.

Newswise: Urologist Study Sheds Light on Androgen Deficiency
Released: 4-Mar-2022 8:05 AM EST
Urologist Study Sheds Light on Androgen Deficiency
University of Miami Health System, Miller School of Medicine

A laboratory study at the Miller School of Medicine’s Desai Sethi Urology Institute has uncovered new clues about the cellular processes that can lead to deficiencies of androgens (male hormones) such as testosterone.

Released: 4-Mar-2022 7:00 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 4-Mar-2022 7:00 AM EST
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Newswise: Convenient wireless charging for home use
Released: 4-Mar-2022 5:05 AM EST
Convenient wireless charging for home use
Aalto University

A uniform charging field makes this new transmitter ideal for consumer devices.

Released: 4-Mar-2022 4:05 AM EST
Changes in air pollution linked with dry spells in Asia and summer heatwaves in Europe
University of Reading

Air pollution increases in South East Asia, combined with pollution cuts in Europe, may have had an important influence on European and Asian weather patterns in recent decades, new research has found.

Newswise: Researchers reconstruct ancient fish lizard
Released: 4-Mar-2022 4:05 AM EST
Researchers reconstruct ancient fish lizard
Lund University

Geologists at Lund University in Sweden have mapped 300 years of research on the prehistoric marine reptiles known as ichthyosaurs.

Released: 4-Mar-2022 4:05 AM EST
COVID-19 restrictions linked to nearly 750,000 fewer dengue cases in 2020
London School of Hygiene and Tropical Medicine

Nearly three quarters of a million fewer global cases of dengue occurred in 2020, which could be linked to COVID-19 disruptions limiting human mobility and contact, according to a new study published in Lancet Infectious Diseases.

Released: 4-Mar-2022 3:45 AM EST
Contextualizing Engagement With Health Information on Facebook: Using the Social Media Content and Context Elicitation Method
Journal of Medical Internet Research

Background: Most of what is known regarding health information engagement on social media stems from quantitative methodologies. Public health literature often quantifies engagement by measuring likes, comments, and/or shares of post...

Released: 4-Mar-2022 3:30 AM EST
The Characteristics and Functionalities of Mobile Apps Aimed at Patients Diagnosed With Immune-Mediated Inflammatory Diseases: Systematic App Search
Journal of Medical Internet Research

Background: Immune-mediated inflammatory diseases (IMIDs) are systemic conditions associated with a high social and health impact. New treatments have changed the prognosis of IMIDs and have increased patient autonomy in disease mana...

Released: 4-Mar-2022 3:05 AM EST
New method to produce chemically modified mRNA developed
University of Cologne

In a recent study, the research group at the University of Cologne’s Institute of Organic Chemistry led by Professor Dr Stephanie Kath-Schorr describes a novel method for the enzymatic production of synthetic messenger RNA (mRNA).

Newswise: Waves on circular paths
Released: 4-Mar-2022 2:05 AM EST
Waves on circular paths
Karlsruhe Institute of Technology (KIT)

Just as electrons flow through an electrical conductor, magnetic excitations can travel through certain materials. Such excitations, known in physics as "magnons" in analogy to the electron, could transport information much more easily than electrical conductors. An international research team has now made an important discovery on the road to such components, which could be highly energy-efficient and considerably smaller.

Released: 4-Mar-2022 2:05 AM EST
Controversial policy to reconcile mining and biodiversity conservation demonstrates success
Bangor University

Ambatovy mine, a major contributor to Madagascar’s economy and a company which positioned itself as a leader in sustainable mining, is on track to deliver ‘No Net Loss’ of the unique forest habitat destroyed by the mine.

Newswise: Gene editing gets safer thanks to redesigned Cas9 protein
Released: 3-Mar-2022 8:15 PM EST
Gene editing gets safer thanks to redesigned Cas9 protein
University of Texas at Austin (UT Austin)

One of the grand challenges with using CRISPR-based gene editing on humans is that the molecular machinery sometimes makes changes to the wrong section of a host’s genome, creating the possibility that an attempt to repair a genetic mutation in one spot in the genome could accidentally create a dangerous new mutation in another.

Released: 3-Mar-2022 5:05 PM EST
妙佑医疗国际研究人员开发出预测胃癌治疗应答的模型
Mayo Clinic

妙佑医疗国际癌症中心(Mayo Clinic Cancer Center)佛罗里达州院区的研究人员正在开展一项研究,以验证使用基因组测序来预测胃癌患者从化疗或免疫疗法中获益的可能性。这项研究已在《自然通讯》(Nature Communications)杂志上发表。

Released: 3-Mar-2022 5:05 PM EST
باحثو مايو كلينك يطوّرون نموذجًا للتنبؤ بالاستجابة لعلاج سرطان المعدة
Mayo Clinic

أثبتت دراسة أجراها باحثون في مركز مايو كلينك للسرطان في فلوريدا صحة استخدام التسلسل الجينومي للتنبؤ باحتمالية استفادة مرضى سرطان المعدة من العلاج الكيميائي أو العلاج المناعي. الدراسة منشورة في مجلة نيتشر كوميونيكيشنز.

Released: 3-Mar-2022 5:05 PM EST
Pesquisadores da Mayo Clinic desenvolvem modelo para prever resposta ao tratamento do câncer de gástrico
Mayo Clinic

Um estudo realizado pelos pesquisadores no Centro de Câncer da Mayo Clinic na Flórida está validando o uso do sequenciamento de genoma para prever a probabilidade de pacientes com câncer gástrico obterem benefícios da quimioterapia ou da imunoterapia. O estudo foi publicado na revista científica Nature Communications.

Newswise: Cutting Losses: ASU engineering research equips solar industry for improved performance
Released: 3-Mar-2022 5:05 PM EST
Cutting Losses: ASU engineering research equips solar industry for improved performance
Arizona State University (ASU)

ASU researchers have succeeded in identifying a technique that makes cadmium, selenium and telluride (CdSeTe) solar cells more efficient than silicon cells.

Released: 3-Mar-2022 4:05 PM EST
Investigadores de Mayo Clinic crean modelo para predecir respuesta a tratamiento contra cáncer gástrico
Mayo Clinic

Un estudio realizado por los investigadores del Centro Oncológico de Mayo Clinic en Florida valida el empleo de la secuenciación genómica para predecir la probabilidad de que la quimioterapia o la inmunoterapia beneficien a los pacientes con cáncer gástrico. El estudio se publicó en Nature Communications.

Released: 3-Mar-2022 3:30 PM EST
Endocrine Society streamlines name change policy for journal authors
Endocrine Society

The Endocrine Society has introduced a policy to make it simpler for authors of articles published in its peer-reviewed journals to update their names following a name change.

Released: 3-Mar-2022 3:05 PM EST
Researchers find natural mechanism to sensitize cancer to immunotherapy
Michigan Medicine - University of Michigan

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

Newswise: Moon jellies appear to be gobbling up zooplankton in Puget Sound
Released: 3-Mar-2022 3:05 PM EST
Moon jellies appear to be gobbling up zooplankton in Puget Sound
University of Washington

University of Washington-led research suggests moon jellies are feasting on zooplankton, the various tiny animals that drift with the currents, in the bays they inhabit. This could affect other hungry marine life, like juvenile salmon or herring — especially if predictions are correct and climate change will favor fast-growing jellyfish.

Released: 3-Mar-2022 2:35 PM EST
Attention! Brain scans can tell if you are paying it
Yale University

Data from brain scans can now answer an age-old question asked by parents and teachers everywhere: Are you paying attention?

   
Released: 3-Mar-2022 2:05 PM EST
Constellations Across Cultures: How Our Visual Systems Pick Out Patterns in the Night Sky
Association for Psychological Science

The Big Dipper, Orion, and the Pleiades are just a few of the many recognizable star patterns in the night sky. New research published in the journal Psychological Science reveals that our visual processing system may explain the striking commonality of constellations across cultures.

   
Released: 3-Mar-2022 2:05 PM EST
Study: Cities Not Fully Engaging Public Health Agencies in Climate Change Planning
Johns Hopkins Bloomberg School of Public Health

In analysis of 22 large cities in 14 countries, more than one-quarter did not report involvement of a public health agency.

Newswise: How 22 large cities address public health in climate adaptation plans
24-Feb-2022 11:40 AM EST
How 22 large cities address public health in climate adaptation plans
PLOS

Cities which involve public health agencies – such as Barcelona and San Francisco – have very different plans.

     
Newswise: Johns Hopkins Medicine Study Says Improvements Needed in Care for People with Prediabetes
Released: 3-Mar-2022 1:30 PM EST
Johns Hopkins Medicine Study Says Improvements Needed in Care for People with Prediabetes
Johns Hopkins Medicine

Johns Hopkins Medicine researchers analyzed electronic health records and insurance claims data to better understand patients with prediabetes in the Johns Hopkins Health System, and then used that information to recommend improvements in prediabetes care applicable to all medical institutions.

Newswise: Robotic pill can orally deliver large doses of biologic drugs
Released: 3-Mar-2022 1:20 PM EST
Robotic pill can orally deliver large doses of biologic drugs
National Institute of Biomedical Imaging and Bioengineering

NIBIB-funded researchers are developing a robotic pill that, after swallowing, can deliver biologic drugs into the stomach, which could provide an alternative method for self-injection for a wide range of therapies.

Newswise: Evidence Bolsters Classification of a Major Spawning Ground for Atlantic Bluefin Tuna Off the Northeast U.S.
Released: 3-Mar-2022 12:55 PM EST
Evidence Bolsters Classification of a Major Spawning Ground for Atlantic Bluefin Tuna Off the Northeast U.S.
Woods Hole Oceanographic Institution

The Slope Sea off the Northeast United States is a major spawning ground for Atlantic bluefin tuna (Thunnus thynnus), a new paper affirms. This finding likely has important implications for population dynamics and the survival of this fish, according to the paper, “Support for the Slope Sea as a major spawning ground for Atlantic bluefin tuna: evidence from larval abundance, growth rates, and particle-tracking simulations,” published in the Canadian Journal of Fisheries and Aquatic Sciences.

Released: 3-Mar-2022 12:35 PM EST
Time off after high school makes college less likely
Cornell University

Academic breaks after high school – even those lasting just a few months – can cause some students, especially those from disadvantaged backgrounds, to forgo enrolling in college altogether, according to new Cornell University research.

Released: 3-Mar-2022 12:30 PM EST
Initial treatment choice for prostate cancer doesn't affect mental health outcomes
Wolters Kluwer Health: Lippincott

Depression and other mental health outcomes are similar for men choosing different options for initial treatment of localized prostate cancer, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Released: 3-Mar-2022 12:10 PM EST
Working, studying in ‘off’ hours can harm motivation
Cornell University

Working a nontraditional schedule, and checking in at all hours of the day, night and weekends, is not necessarily beneficial for the 21st-century workforce, according to new Cornell University research.

   
Newswise: The Carbene is Seen! Unstable Intermediate Finally Found with Mass Spectrometry
Released: 3-Mar-2022 12:05 PM EST
The Carbene is Seen! Unstable Intermediate Finally Found with Mass Spectrometry
Department of Energy, Office of Science

Pyruvic acid is one of the few organic molecules destroyed in the Earth’s inner atmosphere by solar radiation rather than by reactions with highly reactive free radicals. In this study, scientists obtained the first experimental evidence that the primary degradation products are carbon dioxide and the carbene methylhydroxycarbene. This finding is important for synthetic chemistry and scientific understanding of atmospheric chemistry.

Newswise:Video Embedded how-triple-pane-windows-stop-energy-and-money-from-flying-out-the-window
VIDEO
Released: 3-Mar-2022 12:05 PM EST
How Triple-pane Windows Stop Energy (and Money) From Flying Out the Window
Pacific Northwest National Laboratory

Next generation triple-pane windows provide builders with lower cost options and help homeowners conserve energy, reduce noise, and lower home energy bills.

Released: 3-Mar-2022 12:00 PM EST
EPC-EXs improve astrocyte survival and oxidative stress through different uptaking pathways in diabetic hypoxia condition
Stem Cell Research & Therapy

Hyperglycemia contributes to cardiovascular complications in patients with type 2 diabetes. We confirmed that high glucose (HG) induces endothelial dysfunction and cerebral ischemic injury is enlarged in diabe...

Released: 3-Mar-2022 12:00 PM EST
Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246
Stem Cell Research & Therapy

Anti-angiogenic therapy has been shown to be a promising strategy for anti-tumor treatment. Increasing evidence indicates that tumor angiogenesis is affected by exosomes that are secreted by mesenchymal stem c...

Released: 3-Mar-2022 12:00 PM EST
Comparison of two cell-free therapeutics derived from adipose tissue: small extracellular vesicles versus conditioned medium
Stem Cell Research & Therapy

Cell-free therapy has been inspired as a promising approach to overcome the limitations of traditional stem cell therapy. However, the therapeutic effect between extracellular vesicles and conditioned medium w...

Released: 3-Mar-2022 12:00 PM EST
The functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer’s disease: crosstalk between autophagy and apoptosis
Stem Cell Research & Therapy

The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates neuropathology and improves cognitive deficits in animal models with Alzheimer’s disease. However, the underlying mechanism...

Released: 3-Mar-2022 12:00 PM EST
Intrauterine infusion of clinically graded human umbilical cord-derived mesenchymal stem cells for the treatment of poor healing after uterine injury: a phase I clinical trial
Stem Cell Research & Therapy

Intrauterine adhesion and cesarean scar diverticulum are the main complications of poor healing after uterine injury. Human umbilical cord MSCs transplantation has been regarded as the most potential treatment...



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