Graft-versus-host disease (GVHD) is a common fatal complication of hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment option. However, there are currently no second-line tre...
While many physics instructors are beginning to incorporate lessons on diversity, equity, and inclusion in the classroom, it can often feel like an add-on rather than an integral component of becoming a physicist. In The Physics Teacher, scientists are helping to change this by presenting discussions and activities on DEI as a fundamental and essential part of physics training. The team created two approaches for DEI curriculum, replacing a question on a weekly homework assignment with a reflection essay on a topic important to physicists and including activities and discussions during a two-day unit on representation.
In 2010, scientists discovered that African Americans who are born with certain variants of a gene called apolipoprotein L1 (APOL1) have a higher-than-average risk for experiencing chronic kidney disease (CKD). Now, in a new study of African Americans with hypertension, researchers at the Icahn School of Medicine at Mount Sinai find that a community-based approach to reporting APOL1 genetic test results back to individuals may have beneficial effects.
A study on smokers who drink heavily finds that a combination treatment of the drug varenicline and nicotine replacement therapy is more effective for smoking cessation, and that efforts to quit smoking can indirectly lead to reduced drinking rates.
Mice that received treatments with peanut-coated microneedles had significant increased rates of desensitization to peanut allergy compared with epicutaneous immunotherapy (EPIT), a new study found. The microneedle treatment success was achieved despite applying a dose of peanut protein 10-times lower than the dose delivered by EPIT. Researchers say the findings demonstrate the potential for peanut microneedles to improve food allergen immunotherapy through the skin.
A new Harvey L. Neiman Health Policy Institute study found that between 2017 and 2019 the number of non-physician providers (NPPs, which includes nurse practitioners and physician assistants) employed by radiology-only practices increased 18%. This increase was associated with more NPPs employed per practice as well as an 11% increase in the number of practices employing them. This Journal of the American College of Radiology study was based on Centers for Medicare and Medicaid Services databases of doctors and clinicians who participated in Medicare.
A pilot study from Georgia Tech researcher Omer Inan and Emory University psychiatrist Douglas Bremner opens the door to a hopeful new therapeutic alternative for people suffering from PTSD.
Women who were younger at the time of their first menstrual period (menarche) are more likely to report chronic pain in adulthood, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Researchers at the Uniformed Services University in collaboration with University of Washington, have recently uncovered new details about how Nipah and Hendra viruses infect cells and the immune responses that can block them, which could ultimately lead to the development of new tactics to prevent and treat these deadly illnesses.
Mindfulness meditation is a stress-management practice with ancient lineage that cultivates nonjudgmental awareness of the present moment, often by directing attention to the physical sensations of breathing. Initially inspired by centuries-old Buddhist practices consisting of philosophies and meditations together, today a secular version of mindfulness — consisting of meditations alone — is becoming increasingly popular.
The composite tissue transfer techniques used and refined in face transplant surgery may also be used to perform microsurgical replantation – using the person's own tissues – in patients with other types of severe facial injuries, suggests a clinical report in The Journal of Craniofacial Surgery. The journal, under the guidance of Editor-in-Chief Mutaz B. Habal, MD, is published in the Lippincott portfolio by Wolters Kluwer.
A laboratory study at the Miller School of Medicine’s Desai Sethi Urology Institute has uncovered new clues about the cellular processes that can lead to deficiencies of androgens (male hormones) such as testosterone.
… quite high risk of procedure-related stroke after TAVR due to the grade 4
thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel
CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …
… Although rates of clinically overt cerebrovascular events associated with TAVR
are reported to be low—particularly in low-risk patients [26]—… on patient population,
study design, and stroke definition. As we treat more and more patients with TAVR …
Air pollution increases in South East Asia, combined with pollution cuts in Europe, may have had an important influence on European and Asian weather patterns in recent decades, new research has found.
Nearly three quarters of a million fewer global cases of dengue occurred in 2020, which could be linked to COVID-19 disruptions limiting human mobility and contact, according to a new study published in Lancet Infectious Diseases.
Background: Most of what is known regarding health information engagement on social media stems from quantitative methodologies. Public health literature often quantifies engagement by measuring likes, comments, and/or shares of post...
Background: Immune-mediated inflammatory diseases (IMIDs) are systemic conditions associated with a high social and health impact. New treatments have changed the prognosis of IMIDs and have increased patient autonomy in disease mana...
In a recent study, the research group at the University of Cologne’s Institute of Organic Chemistry led by Professor Dr Stephanie Kath-Schorr describes a novel method for the enzymatic production of synthetic messenger RNA (mRNA).
Just as electrons flow through an electrical conductor, magnetic excitations can travel through certain materials. Such excitations, known in physics as "magnons" in analogy to the electron, could transport information much more easily than electrical conductors. An international research team has now made an important discovery on the road to such components, which could be highly energy-efficient and considerably smaller.
Ambatovy mine, a major contributor to Madagascar’s economy and a company which positioned itself as a leader in sustainable mining, is on track to deliver ‘No Net Loss’ of the unique forest habitat destroyed by the mine.
One of the grand challenges with using CRISPR-based gene editing on humans is that the molecular machinery sometimes makes changes to the wrong section of a host’s genome, creating the possibility that an attempt to repair a genetic mutation in one spot in the genome could accidentally create a dangerous new mutation in another.
أثبتت دراسة أجراها باحثون في مركز مايو كلينك للسرطان في فلوريدا صحة استخدام التسلسل الجينومي للتنبؤ باحتمالية استفادة مرضى سرطان المعدة من العلاج الكيميائي أو العلاج المناعي. الدراسة منشورة في مجلة نيتشر كوميونيكيشنز.
Um estudo realizado pelos pesquisadores no Centro de Câncer da Mayo Clinic na Flórida está validando o uso do sequenciamento de genoma para prever a probabilidade de pacientes com câncer gástrico obterem benefícios da quimioterapia ou da imunoterapia. O estudo foi publicado na revista científica Nature Communications.
ASU researchers have succeeded in identifying a technique that makes cadmium, selenium and telluride (CdSeTe) solar cells more efficient than silicon cells.
Un estudio realizado por los investigadores del Centro Oncológico de Mayo Clinic en Florida valida el empleo de la secuenciación genómica para predecir la probabilidad de que la quimioterapia o la inmunoterapia beneficien a los pacientes con cáncer gástrico. El estudio se publicó en Nature Communications.
The Endocrine Society has introduced a policy to make it simpler for authors of articles published in its peer-reviewed journals to update their names following a name change.
Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.
University of Washington-led research suggests moon jellies are feasting on zooplankton, the various tiny animals that drift with the currents, in the bays they inhabit. This could affect other hungry marine life, like juvenile salmon or herring — especially if predictions are correct and climate change will favor fast-growing jellyfish.
The Big Dipper, Orion, and the Pleiades are just a few of the many recognizable star patterns in the night sky. New research published in the journal Psychological Science reveals that our visual processing system may explain the striking commonality of constellations across cultures.
Johns Hopkins Medicine researchers analyzed electronic health records and insurance claims data to better understand patients with prediabetes in the Johns Hopkins Health System, and then used that information to recommend improvements in prediabetes care applicable to all medical institutions.
NIBIB-funded researchers are developing a robotic pill that, after swallowing, can deliver biologic drugs into the stomach, which could provide an alternative method for self-injection for a wide range of therapies.
The Slope Sea off the Northeast United States is a major spawning ground for Atlantic bluefin tuna (Thunnus thynnus), a new paper affirms. This finding likely has important implications for population dynamics and the survival of this fish, according to the paper, “Support for the Slope Sea as a major spawning ground for Atlantic bluefin tuna: evidence from larval abundance, growth rates, and particle-tracking simulations,” published in the Canadian Journal of Fisheries and Aquatic Sciences.
Academic breaks after high school – even those lasting just a few months – can cause some students, especially those from disadvantaged backgrounds, to forgo enrolling in college altogether, according to new Cornell University research.
Depression and other mental health outcomes are similar for men choosing different options for initial treatment of localized prostate cancer, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Working a nontraditional schedule, and checking in at all hours of the day, night and weekends, is not necessarily beneficial for the 21st-century workforce, according to new Cornell University research.
Pyruvic acid is one of the few organic molecules destroyed in the Earth’s inner atmosphere by solar radiation rather than by reactions with highly reactive free radicals. In this study, scientists obtained the first experimental evidence that the primary degradation products are carbon dioxide and the carbene methylhydroxycarbene. This finding is important for synthetic chemistry and scientific understanding of atmospheric chemistry.
Next generation triple-pane windows provide builders with lower cost options and help homeowners conserve energy, reduce noise, and lower home energy bills.
Hyperglycemia contributes to cardiovascular complications in patients with type 2 diabetes. We confirmed that high glucose (HG) induces endothelial dysfunction and cerebral ischemic injury is enlarged in diabe...
Anti-angiogenic therapy has been shown to be a promising strategy for anti-tumor treatment. Increasing evidence indicates that tumor angiogenesis is affected by exosomes that are secreted by mesenchymal stem c...
Cell-free therapy has been inspired as a promising approach to overcome the limitations of traditional stem cell therapy. However, the therapeutic effect between extracellular vesicles and conditioned medium w...
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates neuropathology and improves cognitive deficits in animal models with Alzheimer’s disease. However, the underlying mechanism...
Intrauterine adhesion and cesarean scar diverticulum are the main complications of poor healing after uterine injury. Human umbilical cord MSCs transplantation has been regarded as the most potential treatment...