Feature Channels: Diabetes

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La retinopatía diabética es la causa más común de ceguera en los adultos de edad laboral; sin embargo, la mayoría de los estadounidenses de más de 40 años no conocen sus síntomas ni los factores de riesgo para esta afección común que amenaza la vista, según una encuesta encomendada por la Sociedad Estadounidense de Especialistas en Retina (American Society of Retina Specialists, ASRS).

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Diabetic retinopathy is the leading cause of blindness among working-age adults, yet most Americans over 40 don’t know its symptoms or the risk factors for this common sight-threatening condition, according to a survey commissioned by the American Society of Retina Specialists (ASRS).

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All adults with endocrine disorders should be tested for high cholesterol and triglycerides to evaluate their risk of heart attack or stroke, according to a Clinical Practice Guideline issued today by the Endocrine Society.

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A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effect.

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The Association of Diabetes Care & Education Specialists Foundation and the Certification Board for Diabetes Care and Education are proud to award Julia Blanchette Ph.D., RN, CDCES, a fellowship in integrated diabetes management.

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What about the kidneys make them a hotspot for COVID-19’s cytokine storm? A research team says it’s the presence of a protein found on specialized renal transport cells.

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Patients with diabetic kidney disease can potentially be treated with a new investigational medication that may slow the progress of their illness without harmful side effects to their hearts, according to the results of a global clinical trial announced Friday.

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Transplanting cadaver pancreatic islets is a promising therapy for Type 1 diabetes, but a reactivated autoimmunity means low graft viability after five years. Research now shows that a protective coating of two biopolymers can delay allograft and autoimmune-mediated rejection in mouse models of T1D.

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New research in mice suggests that a high-fat diet early in life may impair male fertility in adulthood. The first-of-its-kind study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism.

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The COVID-19 pandemic has jumpstarted innovation in health care delivery and allowed for real-world testing of diabetes care models in unprecedented ways, according to a manuscript published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Researchers at the University of Chicago Medicine are launching a four-year research trial to test the effects of two evidenced-based interventions for personalized diabetes care for older adults, thanks to a new $5 million grant provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.

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It's long been thought that having "autoreactive" T cells in the pancreas was a sure sign of type 1 diabetes. Yet a new study led by scientists at La Jolla Institute for Immunology (LJI) shows that even healthy people have these cells lurking in the pancreas—in surprisingly high numbers.

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The Cardiometabolic Center Alliance (CMCA), founded by Saint Luke’s Mid America Heart Institute is pleased to announce the addition of University Hospitals Cleveland Medical Center as Key Strategic Partner and Charter Member. As a coalition that seeks to establish Cardiometabolic Centers of Excellence nationwide aimed at transforming the treatment of type 2 diabetes (T2D) and related cardiovascular (CV) and renal comorbidities, the CMCA considers University Hospitals (UH) a large integrated health system based in Cleveland, Ohio a key member of the Alliance.

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Data from COMBINE (OCT-FFR) found that the use of FFR combined with OCT imaging can help improve the accuracy of high-risk lesion identification in patients with diabetes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.

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While older age is widely recognized as a risk factor for increased morbidity and mortality due to COVID-19, younger patients have received less attention as a population vulnerable to adverse clinical outcomes.

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Media invited to live Q&A on Oct 7th, 2pm EDT

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Insulin pumps are widely used in the management of type 1 diabetes (T1D) and reviews have shown insulin pump therapy to be associated with improved glycemic control, fewer severe hypoglycemia events, and improved quality of life. Yet, non-Hispanic white children (NHW) are more than twice as likely as non-Hispanic Black children (NHB) to use this technology.

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A premier medical education opportunity for nurse practitioners and physician assistants.

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Innovative device ensures doctors obtain adequate fluid samples from the eye, helping with diagnosis and individualized treatment plans for patients.

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New findings about body fat help explain the differing health risks men and women face – and set the stage for better, more targeted treatments.

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Today, U.S. Senators Tim Scott (R-SC), Mark Warner (D-VA), Kevin Cramer (R-ND), Kyrsten Sinema (D-AZ), Tom Cotton (R-AR), and Tina Smith (D-MN) introduced the PREVENT DIABETES Act. This legislation would increase access to the Medicare Diabetes Prevention Program (MDPP) Expanded Model by allowing CDC-recognized virtual suppliers to participate in the program.

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The University of New Hampshire will receive $1.8 million from the National Institutes of Health (NIH) that will further molecular research to better understand drug interactions at the cellular level and help lead to the development of new targeted drugs to treat wide-spread metabolic, growth, neurological and visual disorders including diabetes and cancer.

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Patients taking drugs called NRTIs to treat HIV and hepatitis B had a 33% lower risk of developing diabetes.

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A Cleveland Clinic study shows that 5 to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison, about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss. The study is published in the October issue of Annals of Surgery.

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A study led by UC Davis Health researchers uncovered that even one severe episode of diabetic ketoacidosis (DKA) in children newly diagnosed with type 1 diabetes is linked to cognitive problems; and among children with a previous diagnosis, repeated DKA exposure predicted lower cognitive performance after accounting for glycemic control.

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Researchers found that Black young adults who grew up amid economic hardship and exposure to racial discrimination experienced physical deterioration that persisted through adolescence and well into adulthood—even though on the surface, they were successful.

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Early to bed, early to rise…while the old saying promises health, wealth and wisdom, new research confirms part of the adage holds true, as a world first study shows that people who go to bed early are more likely to be in better health and more physically active compared to night owls.

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The Endocrine Society will switch its annual meeting, ENDO 2021, to a fully virtual format, the Society announced today.

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Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.

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DALLAS – Sept. 15, 2020 – Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife. They suggest that drugs used to lower inflammation in the lungs could prove beneficial to obese patients with the disease.

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Published in the journal Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]), the study shows that it is the absence of quality connections with people and not the lack of contact that predicts the onset of type 2 diabetes, suggesting that helping people form and experience positive relationships could be a useful tool in prevention strategies for type 2 diabetes.

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The combined effects of the body's microbiota working together with COVID-19 in the lungs could explain the severity of the disease in people with obesity and diabetes, according to a new article published today in eLife.

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COVID-19 and interlinkages to endocrine and metabolic diseases was an important programme topic at the 2020 European Congress of Endocrinology.

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Children born to mothers who had diabetes during pregnancy may age faster biologically and be at an increased risk for obesity and high blood pressure, according to Rutgers researchers.

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Inflammatory lipid signaling may provoke the autoimmune disease Type 1 diabetes. Researchers have identified a proinflammatory lipid profile that precedes development of T1D in a mouse model and in children under age 15 who are at high risk for T1D. These lipids may be therapeutic targets.

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Adolescence is a difficult period of development, made more complex for those with Type 1 diabetes mellitus (T1DM). The challenges of managing multiple doses of daily insulin administration, blood glucose monitoring, dietary and exercise requirements, can make self-care difficult and complicate outcomes. Adolescents with T1DM often have poorer diabetes outcomes than others, indicating that glucose control is difficult for them to maintain.

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Researchers have developed a novel ‘disease-in-a-dish’ model to study the basic molecular factors that lead to the development of type 2 diabetes, uncovering the potential existence of major signaling defects both inside and outside of the classical insulin signaling cascade, and providing new perspectives on the mechanisms behind insulin resistance in type 2 diabetes and possibly opportunities for the development of novel therapeutics for the disease.

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From MasterChef to MKR, the world’s best chefs have taught us how to barbeque, grill and panfry a steak to perfection. But while the experts may be seeking that extra flavour, new research from the University of South Australia suggests high-heat caramelization could be bad for our health.

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Patients with diabetes are at a higher risk of mortality when discharged from hospital

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DALLAS – Sept. 1, 2020 – Roger H. Unger, M.D., a longtime Professor of Internal Medicine, a preeminent authority on glucagon and the development of diabetes, and the founding Director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, died Aug. 22. He was 96.

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Researchers at the Georgia Institute of Technology and University of Missouri developed a new microgel drug delivery method that could extend the effectiveness of pancreatic islet transplantations — from several years to possibly the entire lifespan of a recipient.

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A new artificial pancreas system can prevent hypoglycemia—episodes of dangerously low blood sugar—during and after heavy exercise in people with type 1 diabetes, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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An artificial pancreas originally developed at the University of Virginia Center for Diabetes Technology safely and effectively manages blood sugar levels in children ages 6 to 13 with type 1 diabetes, a national clinical trial has found.

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A potential therapy for obesity would transplant HUMBLE (human brown-like) fat cells, human white fat cells that have been genetically modified using CRISPR to become similar to heat-generating brown fat cells.

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Blocking nerve signals to the pancreas could stop patients from ever developing type 1 diabetes.

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A review of COVID-19 studies reveals a troubling connection between two health crises: coronavirus and obesity.

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Getting more sleep, and establishing a regular sleep schedule, is a common recommendation for maintaining and improving health, including for people with Type 1 diabetes. Short sleep patterns may affect how the body uses insulin, and irregular sleep schedules can affect glucose through changes in one's circadian rhythm or biological clock.