Curated News: National Eye Institute (NEI)

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Newswise:Video Embedded nei-scientists-publish-recipe-for-making-blood-vessel-cells-from-patient-stem-cells
VIDEO
Released: 16-May-2023 9:30 AM EDT
NEI Scientists publish recipe for making blood vessel cells from patient stem cells
NIH, National Eye Institute (NEI)

Researchers at NIH’s National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries.

Released: 1-May-2023 6:05 PM EDT
Scientists discover anatomical changes in the brains of the newly sighted
Massachusetts Institute of Technology (MIT)

In a new study, Sinha and his colleagues have now discovered anatomical changes that occur in the brains of these patients after their sight is restored. These changes, seen in the structure and organization of the brain’s white matter, appear to underlie some of the visual improvements that the researchers also observed in these patients.

Newswise: Herpes study adds to understanding of viral reinfections, how to potentially prevent them
Released: 1-May-2023 10:25 AM EDT
Herpes study adds to understanding of viral reinfections, how to potentially prevent them
University of Illinois Chicago

A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.

Newswise: Extremely rare gene variants point to a potential cause of age-related macular degeneration
29-Mar-2023 2:00 PM EDT
Extremely rare gene variants point to a potential cause of age-related macular degeneration
NIH, National Eye Institute (NEI)

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

Newswise: Extremely rare gene variants point to a potential cause of age-related macular degeneration
29-Mar-2023 2:00 PM EDT
Extremely rare gene variants point to a potential cause of age-related macular degeneration
NIH, National Eye Institute (NEI)

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

Newswise: FDA-approved drug shows promise in lab models for blinding childhood disease 
Released: 29-Mar-2023 12:05 PM EDT
FDA-approved drug shows promise in lab models for blinding childhood disease 
NIH, National Eye Institute (NEI)

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

Newswise: FDA-approved drug shows promise in lab models for blinding childhood disease 
Released: 29-Mar-2023 12:05 PM EDT
FDA-approved drug shows promise in lab models for blinding childhood disease 
NIH, National Eye Institute (NEI)

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

Newswise: Early study shows cones in retinal degeneration, thought to be dormant, may retain visual function
Released: 27-Mar-2023 5:40 PM EDT
Early study shows cones in retinal degeneration, thought to be dormant, may retain visual function
University of California, Los Angeles (UCLA), Health Sciences

New UCLA research in mice suggests that “dormant” cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

Newswise: Tiny nanoparticle could have big impact on patients receiving corneal transplants
Released: 24-Mar-2023 3:25 PM EDT
Tiny nanoparticle could have big impact on patients receiving corneal transplants
Virginia Commonwealth University (VCU)

Corneal transplants can be the last step to returning clear vision to many patients suffering from eye disease. Each year, approximately 80,000 corneal transplantations take place in the U.S. Worldwide, more than 184,000 corneal transplantation surgeries are performed annually.

   
Newswise: Visually navigating on foot uses unique brain region
Released: 15-Mar-2023 8:45 AM EDT
Visually navigating on foot uses unique brain region
NIH, National Eye Institute (NEI)

Using vision to efficiently move through an area by foot uses a unique region of the brain’s cortex, according to a small study funded by the National Eye Institute (NEI).

Newswise: AI-based systems can help identify rapidly advancing age-related macular degeneration
Released: 14-Mar-2023 3:35 PM EDT
AI-based systems can help identify rapidly advancing age-related macular degeneration
NIH, National Eye Institute (NEI)

Researchers supported by the National Eye Institute are developing artificial intelligence/machine learning (AI/ML)-based systems that not only screen for AMD but also predict which patients will likely progress to late within two years. The systems also evaluate separately one’s risk for developing late wet (neovascular) AMD from one’s risk for late dry (geographic atrophy) AMD.

Newswise: AI-based systems can help identify rapidly advancing age-related macular degeneration
Released: 14-Mar-2023 3:35 PM EDT
AI-based systems can help identify rapidly advancing age-related macular degeneration
NIH, National Eye Institute (NEI)

Researchers supported by the National Eye Institute are developing artificial intelligence/machine learning (AI/ML)-based systems that not only screen for AMD but also predict which patients will likely progress to late within two years. The systems also evaluate separately one’s risk for developing late wet (neovascular) AMD from one’s risk for late dry (geographic atrophy) AMD.

Newswise: New Insights: Eye Damage in Alzheimer’s Disease Patients
Released: 3-Mar-2023 10:05 AM EST
New Insights: Eye Damage in Alzheimer’s Disease Patients
Cedars-Sinai

Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina—a layer of tissue at the back of the eye where visual information originates—and how those retinal changes correspond to brain and cognitive changes in Alzheimer’s disease patients.

Newswise: Eye experts weigh in on artificial tears in midst of infectious outbreak
Released: 2-Mar-2023 1:15 PM EST
Eye experts weigh in on artificial tears in midst of infectious outbreak
NIH, National Eye Institute (NEI)

Questions remain about artificial tears linked to an outbreak of Pseudomonas aeruginosa infections involving 64 people in 13 states, including 8 cases of vision loss, as well as lung and urinary tract infections, and one death. Federal agencies warned people to stop using EzriCare and Delsam Pharma artificial tears after tests of opened bottles used by those affected found a rare, extensively drug-resistant strain of P. aeruginosa. The strain had never been reported in the United States.What is clear is that eye health experts have advice for people using artificial tears, which are sold over the counter and widely used for eye irritation associated with dry eye disease, contact lens use, and refractive surgery, as well among those using other eye drops regularly, such as for glaucoma.

Newswise: Eye experts weigh in on artificial tears in midst of infectious outbreak
Released: 2-Mar-2023 1:15 PM EST
Eye experts weigh in on artificial tears in midst of infectious outbreak
NIH, National Eye Institute (NEI)

Questions remain about artificial tears linked to an outbreak of Pseudomonas aeruginosa infections involving 64 people in 13 states, including 8 cases of vision loss, as well as lung and urinary tract infections, and one death. Federal agencies warned people to stop using EzriCare and Delsam Pharma artificial tears after tests of opened bottles used by those affected found a rare, extensively drug-resistant strain of P. aeruginosa. The strain had never been reported in the United States.What is clear is that eye health experts have advice for people using artificial tears, which are sold over the counter and widely used for eye irritation associated with dry eye disease, contact lens use, and refractive surgery, as well among those using other eye drops regularly, such as for glaucoma.

Newswise: How Common is Face Blindness?
Released: 27-Feb-2023 12:05 PM EST
How Common is Face Blindness?
Harvard Medical School

Face blindness, a mystifying condition that can trick us into believing we recognize people we’ve never met or make us fail to recognize those we have, has been previously estimated to affect between 2 and 2.5 percent of people in the world. Now, a new study by researchers at Harvard Medical School (HMS) and the VA Boston Healthcare System is providing fresh insights into the disorder, suggesting it may be more common than currently believed.

Newswise: Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
2-Feb-2023 11:05 AM EST
Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
NIH, National Eye Institute (NEI)

While early treatment of diabetes-related eye disease slowed progression to severe disease, it did not improve visual acuity compared with treating more severe disease once it developed, according to a clinical study from the DRCR Retina Network.

Newswise: Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
2-Feb-2023 11:05 AM EST
Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
NIH, National Eye Institute (NEI)

While early treatment of diabetes-related eye disease slowed progression to severe disease, it did not improve visual acuity compared with treating more severe disease once it developed, according to a clinical study from the DRCR Retina Network.

Newswise: Researchers Unravel Why Episodes of Low Blood Sugar Worsen Eye Disease in People with Diabetes
Released: 26-Jan-2023 9:00 AM EST
Researchers Unravel Why Episodes of Low Blood Sugar Worsen Eye Disease in People with Diabetes
Johns Hopkins Medicine

People with diabetes who experience periods of low blood sugar — a common occurrence in those new to blood sugar management — are more likely to have worsening diabetic eye disease. Now, researchers at Johns Hopkins Medicine say they have linked such low blood sugar levels with a molecular pathway that is turned on in oxygen-starved cells in the eye.



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