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HIV Lessons From the Mississippi Baby

The news in July that HIV had returned in a Mississippi toddler after a two-year treatment-free remission dashed the hopes of clinicians, HIV researchers and the public at large tantalized by the possibility of a cure. But a new commentary by two leading HIV experts at Johns Hopkins argues that despite its disappointing outcome, the Mississippi case and two other recent HIV “rebounds” in adults, have yielded critical lessons about the virus’ most perplexing — and maddening — feature: its ability to form cure-defying viral hideouts.

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New Analysis of Old HIV Vaccines Finds Potentially Protective Immune Response

Applying the benefit of hindsight, researchers at Duke Medicine have reanalyzed the findings of two historic pediatric HIV vaccine trials with encouraging results. The vaccines had in fact triggered an antibody response -- now known to be associated with protection in adults -- that was previously unrecognized in the infants studied in the 1990s.

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Gang Life Brings Deep Health Risks for Girls

Being involved in a gang poses considerable health-related risks for adolescent African American girls, including more casual sex partners and substance abuse combined with less testing for HIV and less knowledge about preventing sexually transmitted diseases, according to a new study.

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Dosage of HIV Drug May Be Ineffective for Half of African-Americans

Many African-Americans may not be getting effective doses of the HIV drug maraviroc because they are more likely than European-Americans to inherit functional copies of a protein that speeds the removal of the drug from the body.

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Op-Ed: Nurses Know Danger, Forge Ahead on Ebola Care

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Ever since Florence Nightingale, “The Lady With the Lamp,” took it upon herself to care for the sick and the wounded in the Crimean War in the 1850s, nurses have proven their value and their valor where care is most daunting and risky.

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Antibodies, Together with Viral ‘Inducers,’ Found to Control HIV in Mice

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Although HIV can now be effectively suppressed using anti-retroviral drugs, it still comes surging back the moment the flow of drugs is stopped. Latent reservoirs of HIV-infected cells, invisible to the body’s immune system and unreachable by pharmaceuticals, ensure that the infection will rebound after therapy is terminated.

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RTI International and the South African Medical Research Council to Address the State of Populations Most-at-Risk for HIV in Cape Town, South Africa

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As part of an ongoing effort to reduce HIV transmission in South Africa, RTI International and the South African Medical Research Council (SAMRC) are co-hosting a policy forum to address the state of key populations at risk of HIV in the Western Cape and discuss findings from two recent prevention studies funded by the U.S. National Institutes of Health.

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Scientists Detail Urgent Research Agenda to Better Understand, Address Chronic Disease Toll

According to recommendations resulting from a multidisciplinary conference sponsored by the National Institutes of Health, scientists and physicians in low- and middle-income countries should build on existing HIV research to study and treat chronic conditions.

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Gut Flora Influences HIV Immune Response

Normal microorganisms in the intestines appear to play a pivotal role in how the HIV virus foils a successful attack from the body’s immune system, according to new research from Duke Medicine.

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With Advances in HIV Care, Survivors Face Other Disease Risks

As effective treatments for HIV become more widely available in low- and middle-income countries, there's an urgent need to assess and manage health risks in the growing number of people living with HIV. An update on non-communicable diseases (NCDs) among HIV-positive populations in LMICs appears as a supplement to in JAIDS: Journal of Acquired Immune Deficiency Syndromes. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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