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A reporter's PressPass is required to access this story until the embargo expires on 30-Jun-2016 12:00 AM EDT

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Novel Study in Nairobi Infants May Accelerate Path to HIV Vaccine

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The first and only study to look at isolate HIV-neutralizing antibodies from infants has found that novel antibodies that could protect against many variants of HIV can be produced relatively quickly after infection compared to adults.

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Autologous Stem Cell Transplantation Offers Safe and Effective, and Potentially Curative, Option for Patients with HIV-Associated Lymphoma

Multicenter, phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed/treatment-resistant lymphoma.

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Loyola Study Reveals How HIV Enters Cell Nucleus

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Loyola scientists have solved a mystery that has long baffled HIV researchers: How does HIV manage to enter the nucleus of immune system cells? The discovery, reported in the journal PLOS Pathogens, could lead to effective new drugs to treat HIV/AIDS.

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NYU Meyers and Penn St. Awarded $5.8M NIH Grant to Improve Health for Minorities Living with HIV

The study will utilize an engineering-inspired framework to design an intervention to increase engagement along the HIV care continuum for African American/Black and Hispanic People Living with HIV who are neither taking antiretroviral therapy (ART) nor well engaged in HIV primary care.

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Top HIV Scientists Awarded $42 Million in National Institutes of Health Funding to Improve Efficacy of HIV Vaccine Platforms

With $42 million in funding from the National Institutes of Health, scientists from Beth Israel Deaconess Medical Center (BIDMC) and Oregon Health & Science University (OHSU) will lead a five-year research initiative to advance efforts to cure and prevent HIV/AIDS. Dan Barouch, MD, PhD, Director of the Center for Virology and Vaccine Research at BIDMC, and Louis Picker, MD, Assistant Director of the OHSU Vaccine and Gene Therapy Institute, will lead a consortium of researchers from across the country exploring the mechanisms behind promising new HIV vaccine candidates and potential cure strategies.

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Study Underscores Ongoing Need for HIV Safety Net Program

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A Johns Hopkins University School of Medicine study of insurance coverage of more than 28,000 people with HIV concludes that a decades-old program that offers free medical care remains a critical necessity despite the availability of coverage under the Affordable Care Act (ACA).

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Simulations Describe HIV’s ‘Diabolical Delivery Device’

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University of Chicago scientists and their colleagues have developed an innovative computer model of HIV that gives real insight into how a virus “matures” and becomes infective.

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Milken Institute School of Public Health Receives Two Grants for a Total of $7 Million to Study Microbiome and Disease Prevention

The Milken Institute School of Public Health at the George Washington University (Milken Institute SPH) today announced receiving two separate awards for a total of $7 million to study the human microbiome, the collection of bacteria and other microbes that live in and on the human body. The first study, a $3.3 million award from the National Institute of Allergy and Infectious Diseases (NIAID), will focus on the bacterial ecosystem of the penis and how it may affect an individual’s risk for acquiring an HIV infection. The second study, a $3.7 million award from NIAID, will focus on bacteria living in the human nose with the goal of finding strategies to protect people from dangerous Staph infections.

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A New Way to Nip AIDS in the Bud

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When new HIV particles bud from an infected cell, the enzyme protease activates to help the viruses infect more cells. Modern AIDS drugs control the disease by inhibiting protease. Now, University of Utah researchers showed that if they delay the budding of new HIV particles, protease itself will destroy the virus instead of helping it spread. That that might lead to new AIDS drugs in a decade.

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Mount Sinai Researchers Track HIV in Real Time as It Infects and Spreads in Living Tissue

By watching brightly glowing HIV-infected immune cells move within mice, researchers at the Icahn School of Medicine at Mount Sinai have shown how infected immune cells latch onto an uninfected sister cell to directly transmit newly minted viral particles.

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Penn Study Describes a Better Animal Model to Improve HIV Vaccine Development

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Vaccines are usually medicine’s best defense against the world’s deadliest microbes. However, HIV is so mutable that it has so far effectively evaded both the human immune system and scientists’ attempts to make an effective vaccine to protect against it. Now, researchers have figured out how to make a much-improved research tool that they hope will open the door to new and better HIV vaccine designs.

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Alcohol Decreases Use of Condoms, Increases HIV Risk

Alcohol use, especially at binge levels, is associated with sexual HIV-risk behavior, but the mechanisms through which alcohol increases sexual risk taking are not well understood. This study addresses that gap.

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RNA Simulations Boost Understanding of Retroviral Diseases

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New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases.

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Too Much Sex Causes Genitals to Change Shape in Beetle Study, Expert on Managing Wedding Stress, Relationship Satisfaction Depends on the Mating Pool, and more in the Sex and Relationships Channel

Click to go to the Sex and Relationships News Source

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Antiretroviral Therapy May Not Be Enough to Reduce HIV-Associated Arterial Inflammation

Additional immune-system-modulatory approaches may help reduce risk of cardiovascular disease.

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Creighton Pharmacy Professor Publishes on Potential for Drug to Stave Off HIV

Chris Destache, Pharm.D., earned a National Institutes for Health grant last year to look into using HIV drug nanoparticles fabricated with a FDA-approved biocompatible polymer and how those drug-ladened nanoparticles can be used to help prevent HIV.

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Neutrons Probe Structure of Enzyme Critical to Development of Next-Generation HIV Drugs

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A team led by the Department of Energy’s Oak Ridge National Laboratory used neutron analysis to better understand a protein implicated in the replication of HIV, the retrovirus that causes AIDS. The enzyme, known as HIV-1 protease, is a key drug target for HIV and AIDS therapies. The multi-institutional team used neutron crystallography to uncover detailed interactions of hydrogen bonds at the enzyme’s active site, revealing a pH-induced proton ‘hopping’ mechanism that guides its activity.

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UB Partners with University of Zimbabwe to Launch $1.3 Million HIV Research Program

To train future HIV researchers, the University at Buffalo and University of Zimbabwe have partnered to form the HIV Research Training Program, supported by a $1.3 million grant from the National Institutes of Health (NIH) John E. Fogarty International Center.

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Experimental HIV Vaccine Regimen to Be Tested in Large-Scale Clinical Trial; Could Lead to First Licensed AIDS Vaccine.

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