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Stem Cell Gene Therapy Could Be Key to Treating Duchenne Muscular Dystrophy

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Scientists at UCLA have developed a new approach that could eventually be used to treat Duchenne muscular dystrophy. The stem cell gene therapy could be applicable for 60 percent of people with Duchenne, which affects approximately 1 in 5,000 boys in the U.S. and is the most common fatal childhood genetic disease.

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On Darwin's Birthday, Tomato Genetics Study Sheds Light on Plant Evolution

On Charles Darwin's 207th birthday, a new study of evolution in a diverse group of wild tomatoes is shedding light on the importance of genetic variation in plants.

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Communications Professor Devotes Life, Faith to Education of Sickle Cell Disease

Bolanle Olaniran, who lost two brothers to the disease, was diagnosed in 1974.

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Mussel-Mimicking Adhesive Polymer Shown to Be Non-Toxic to Cells

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Chemical Cages: New Technique Advances Synthetic Biology

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes. In a new study, Hao Yan, director of the Center for Molecular Design and Biomimetics at ASU's Biodesign Institute presents a clever means of localizing and confining enzymes and the substrate molecules they bind with, speeding up reactions essential for life processes.

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Wisconsin Researchers Transform Common Cell to Master Heart Cell

By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin-Madison have generated master heart cells — primitive progenitors that form the developing heart. If replicated in human cells, the feat could one day fuel drug discovery, powerful new models for heart disease and the raw material for treating diseased hearts.

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Alternative Proteins Encoded by the Same Gene Have Widely Divergent Functions in Cells

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In a first large-scale systematic study, researchers at Dana-Farber Cancer Institute, University of California, San Diego School of Medicine, and McGill University found that most sibling proteins – known as “protein isoforms” encoded by the same gene – often play radically different roles within tissues and cells, however alike they may be structurally.

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TSRI Study Reveals New Link Between Brain and Fat-Burning Circuit

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A new study in animal models, led by scientists at The Scripps Research Institute, is the first to show that oxygen sensing in the brain has a role in metabolism and sensing an organism’s internal state.

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Rutgers Microbiologist Helped Crack the Genetic Code That Revolutionized Medicine and Agriculture

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When Joachim Messing discovered a way to crack the genetic code of humans and plants like rice, corn and wheat, he did not patent his work. Instead, he gave away the tools he invented – for free – to his fellow scientists around the world because he believed it was vital for future research.

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A Heart-Shaped Protein

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From cookies and candies to balloons and cards, heart-shaped items abound this time of year. They're even in our blood. It turns out that the most abundant protein molecule in blood plasma—serum albumin (SA)—is shaped very much like a heart.

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Mayo Clinic Researchers on Aging Show Long-Term Benefits of “Senolytic” Drugs on Vascular Health in Mice

Building on previous studies, Mayo Clinic researchers have demonstrated significant health improvements in the vascular system of mice following repeated treatments to remove senescent cells. They say this is the first study to show that regular and continual clearance of senescent cells improves age-related vascular conditions – and that the method may be a viable approach to reduce cardiovascular disease and death. The findings appear online in Aging Cell.

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Mechanism That Unwinds DNA May Function Similar to an Oil Rig “Pumpjack”

A team of scientists led by Stony Brook University biochemist Huilin Li, PhD, have proposed that DNA is unwound by a type of “pumpjack” mechanism, similar to the way one operates on an oil rig.

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Cell News—Remember Where You’re Going?

In bloodhounds and neutrophils, getting the scent is not enough. Dogs and immune cells have to remember the chemoattractant they are pursuing, even when it momentarily fades out or threatens to overwhelm.

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Slime Can See

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Scientists discover that slime-forming bacteria act as optical objects.

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A Child’s Cardiac Arrest Should Prompt Check-Ups for the Rest of the Family

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With fewer than 3,500 episodes a year, cardiac arrest in children is decidedly rare, but it could be a dramatic signal that the victim’s family members may be at a heightened risk for sudden cardiac death. This is why, in the aftermath of such a traumatic event, clinical evaluation of the child’s parents and siblings could lead to lifesaving diagnoses and therapies, averting further tragedy, say cardiologists at Ann & Robert H. Lurie Children’s Hospital of Chicago

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Gut Environment Could Reduce Severity of Malaria

Microorganisms in the gut could play a role in reducing the severity of malaria, according to a new study co-authored by researchers at the University of Tennessee, Knoxville, and the University of Louisville.

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Physics: It's What's Happening Inside Your Body Right Now

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Using a model blood vessel system built on a polymer microchip, researchers have shown that the relative softness of white blood cells determines whether they remain in a dormant state along vessel walls or enter blood circulation to fight infection.

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Rice Lab Offers New Strategies, Tools for Genome Editing

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Bioengineer Gang Bao and team explore CRISPR-Cas9 alternatives.

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Uncovering the Secrets of Elastin’s Flexibility

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Protein that gives blood vessels and skin their stretchability has its molecular properties revealed.

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Why Your Muscles Get Less Sore as You Stick with Your Gym Routine

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BYU research shows unexpected immune system cells may help repair muscles.