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Powerful New Method IDs Therapeutic Antibodies
Scientists at The Scripps Research Institute have devised a powerful new technique for finding antibodies that have a desired biological effect. The newly reported technique should greatly speed the process of discovering medicines, diagnostics and laboratory reagents. |
Embargo expired: 5/23/2013 12:00 PM EDT
Released: 5/21/2013 3:25 PM EDT
Scripps Research Institute |
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Protein Preps Cells to Survive Stress of Cancer Growth and Chemotherapy
Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors. |
Embargo expired: 5/23/2013 12:00 PM EDT
Released: 5/22/2013 5:05 PM EDT
Salk Institute for Biological Studies |
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Common Childhood Asthma Not Rooted in Allergens, InflammationAllergens? No. Inflammation? No. An over-active gene that interrupts lipid synthesis appears to be the cause of 20-30% childhood asthma cases. |
Released: 5/23/2013 10:25 AM EDT
Columbia University Medical Center |
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Bacterium From Canadian High Arctic Offers Clues to Possible Life on Mars
The recent discovery by a McGill University led team of scientists of a bacterium that is able to thrive at –15ºC, the coldest temperature ever reported for bacterial growth, is exciting because it offers clues about some of the necessary preconditions for microbial life on Mars. |
Released: 5/23/2013 10:00 AM EDT
McGill University |
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The Secret Lives (and Deaths) of Neurons
University of North Carolina School of Medicine researchers uncover surprising insights about how nerve cells rewire themselves, shedding light on a process linked with neurodegenerative diseases and neurodevelopmental disorders like schizophrenia and autism. |
Released: 5/23/2013 9:30 AM EDT
University of North Carolina School of Medicine |
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How Immune System Peacefully Co-Exists with “Good” Bacteria
The human gut is loaded with helpful bacteria microbes, yet the immune system seemingly turns a blind eye. Now, researchers know how this friendly truce is kept intact. Innate lymphoid cells directly limit the response by inflammatory T cells to commensal bacteria in the gut of mice. Loss of this ILC function effectively puts the immune system on an extended war footing against the commensal bacteria a condition observed in multiple chronic inflammatory diseases. |
Embargo expired: 5/22/2013 1:00 PM EDT
Released: 5/20/2013 3:00 PM EDT
Perelman School of Medicine at the University of Pennsylvania |
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Protein Study Suggests Drug Side Effects are Inevitable
A new study of both computer-created and natural proteins suggests that the number of unique pockets – sites where small molecule pharmaceutical compounds can bind to proteins – is surprisingly small, meaning drug side effects may be impossible to avoid. |
Embargo expired: 5/20/2013 3:00 PM EDT
Released: 5/17/2013 2:00 PM EDT
Georgia Institute of Technology, Research Communications |
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Newly Described Type of Immune Cell and T cells Share Similar Path to MaturityInnate lymphoid cells protect boundary tissues such as the skin, lung, and the gut from microbial onslaught. They also have shown they play a role in inflammatory disease. Researchers have found that maturation of ILC2s requires T-cell factor 1 to move forward. They describe in Immunity that one mechanism used to build ILCs is the same as that in T cells. Both cell types use a protein pathway centered on Notch. |
Released: 5/14/2013 1:50 PM EDT
Perelman School of Medicine at the University of Pennsylvania |
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Zinc: The Goldilocks Metal for Bioabsorbable Stents?
Some materials dissolve too quickly, before cardiac arteries can fully heal, and some hang around forever. Zinc, however, may be just right. |
Released: 5/14/2013 9:05 AM EDT
Michigan Technological University |
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Out of Sync: Body Clocks Altered at Cell Level in Depression
Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. But new research shows that the clock may be broken in the brains of people with depression -- even at the level of the gene activity inside their brain cells. |
Embargo expired: 5/13/2013 3:00 PM EDT
Released: 5/10/2013 8:00 AM EDT
University of Michigan Health System |