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Newswise: Biodiversity appears to strongly suppress pathogens and pests in many plant and animal systems, but this “dilution effect” can vary strikingly in magnitude
23-Feb-2024 2:40 PM EST
Biodiversity appears to strongly suppress pathogens and pests in many plant and animal systems, but this “dilution effect” can vary strikingly in magnitude
PLOS

This study uses forest inventory data from over 25,000 plots to show that the prevalence of tree pests is jointly controlled by the diversity and phylogenetic composition of forests.

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Newswise: Binghamton University Biologist Named Fellow of American Academy of Microbiology
Released: 27-Feb-2024 8:00 AM EST
Binghamton University Biologist Named Fellow of American Academy of Microbiology
Binghamton University, State University of New York

Binghamton University, State University of New York researcher Karin Sauer is among 65 scientists elected as Fellows of the American Academy of Microbiology this year. Fellows are elected by their peers based on their scientific achievements and original contributions to the field of microbiology.

Newswise: Vaping can increase susceptibility to infection by SARS-CoV-2
Released: 27-Feb-2024 6:05 AM EST
Vaping can increase susceptibility to infection by SARS-CoV-2
University of California, Riverside

Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a University of California, Riverside, study has found.

access_time Embargo lifts in 2 days
This news release is embargoed until 28-Feb-2024 11:00 AM EST Released to reporters: 26-Feb-2024 1:05 PM EST

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Released: 26-Feb-2024 12:00 PM EST
Advances in the differentiation of pluripotent stem cells into vascular cells
World Journal of Stem Cells

Blood vessels constitute a closed pipe system distributed throughout the body, transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys. Changes in blood vessels are related to

Released: 26-Feb-2024 12:00 PM EST
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling
World Journal of Stem Cells

BACKGROUNDColorectal cancer stem cells (CCSCs) are heterogeneous cells that can self-renew and undergo multidirectional differentiation in colorectal cancer (CRC) patients. CCSCs are generally accepted to be important sources of CRC and are

Released: 26-Feb-2024 12:00 PM EST
Therapeutic utility of human umbilical cord-derived mesenchymal stem cells-based approaches in pulmonary diseases: Recent advancements and prospects
World Journal of Stem Cells

Pulmonary diseases across all ages threaten millions of people and have emerged as one of the major public health issues worldwide. For diverse disease conditions, the currently available approaches are focused on alleviating clinical sympt

Released: 26-Feb-2024 12:00 PM EST
Cellular preconditioning and mesenchymal stem cell ferroptosis
World Journal of Stem Cells

In this editorial, we comment on the article published in the recent issue of the World Journal of Stem Cells. They focus on stem cell preconditioning to prevent ferroptosis by modulating the cystathionine γ-lyase/hydrogen sulfide (H2S) pa

Released: 26-Feb-2024 12:00 PM EST
High quality repair of osteochondral defects in rats using the extracellular matrix of antler stem cells
World Journal of Stem Cells

BACKGROUNDCartilage defects are some of the most common causes of arthritis. Cartilage lesions caused by inflammation, trauma or degenerative disease normally result in osteochondral defects. Previous studies have shown that decellularized

Released: 26-Feb-2024 12:00 PM EST
Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro
World Journal of Stem Cells

BACKGROUNDIn vitro expansion to increase numbers of hematopoietic stem cells (HSCs) in cord blood could improve clinical efficacy of this vital resource. Nicotinamide (NAM) can promote HSC expansion ex vivo, but its effect on hematopoietic

Newswise: Roswell Park Study First to Show Two-Drug Combination Selectively Targets p53-Mutant Cancers
Released: 26-Feb-2024 11:30 AM EST
Roswell Park Study First to Show Two-Drug Combination Selectively Targets p53-Mutant Cancers
Roswell Park Comprehensive Cancer Center

A preclinical study led by a team of researchers at Roswell Park Comprehensive Cancer Center highlights the potential of a novel two-drug treatment strategy targeting p53-mutant cancers.

Newswise: UT Southwestern finds genetic clues to complex infections
Released: 26-Feb-2024 10:05 AM EST
UT Southwestern finds genetic clues to complex infections
UT Southwestern Medical Center

Treating complex bacterial infections with customized therapies tailored to the infection and the patient is closer to reality, thanks to researchers at UT Southwestern Medical Center.

Released: 26-Feb-2024 10:05 AM EST
MSU, PSU bile acid discoveries redefine microbiome
Michigan State University

In a new paper published in the journal Nature, Michigan State University researchers Robert Quinn and Doug Guzior report the discovery of the enzyme responsible for producing microbially conjugated bile acids, some of the most abundant and crucial molecules in our gut.

23-Feb-2024 3:05 PM EST
Shifting focus: Investigators describe changes to pancreatic β cell at onset of Type 1 Diabetes
Joslin Diabetes Center

About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced “beta”) in the pancreas, leading to a lack of insulin and inability to regulate blood sugar. It’s not known why the body suddenly perceives its own β-cells as the enemy; some lines of evidence suggest environmental factors such as viral infections may trigger the onset of T1D, others suggest genetics may also play some role. Groundbreaking research by investigators at Joslin Diabetes Center sheds new light on the specific changes β-cells go through at the onset of T1D. Their findings—published in Nature Cell Biology—offer new avenues for targeted interventions for the chronic autoimmune condition.

Released: 23-Feb-2024 8:05 PM EST
Researchers explore whether gut microbes cause some COVID-19 patients to have higher blood clot risk
Cell Press

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

Released: 23-Feb-2024 2:45 PM EST
MD Anderson acquires inducible switch technologies for cell therapy
University of Texas MD Anderson Cancer Center

MD Anderson has acquired certain assets from Bellicum Pharmaceuticals, Inc. related to the CaspaCIDE switch and GoCAR platforms. As a result, MD Anderson may incorporate these technologies into its own cell therapy programs as well as make them available for licensing to interested parties.

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This news release is embargoed until 29-Feb-2024 2:05 PM EST Released to reporters: 23-Feb-2024 12:05 PM EST

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Newswise: Giant inflatable colon comes to UCLA to help raise awareness on rising number of people being diagnosed with colorectal cancer
Released: 23-Feb-2024 11:05 AM EST
Giant inflatable colon comes to UCLA to help raise awareness on rising number of people being diagnosed with colorectal cancer
University of California, Los Angeles (UCLA), Health Sciences

For Colon Cancer Awareness Month, experts from the UCLA Health will educate members of the community on the importance of starting colorectal cancer screening early and continuing to have it done regularly throughout their lives to prevent the development of cancer.

Newswise: Biomolecular condensates – regulatory hubs for plant iron supply
Released: 23-Feb-2024 10:05 AM EST
Biomolecular condensates – regulatory hubs for plant iron supply
Heinrich-Heine-Universität Düsseldorf

Iron is a micronutrient for plants. Biologists from the Institute of Botany at Heinrich Heine University Düsseldorf (HHU) describe in a study, which has now been published in the Journal of Cell Biology, that regulatory proteins for iron uptake behave particularly dynamically in the cell nucleus when the cells are exposed to blue light – an important signal for plant growth.

Newswise: Wistar Scientists Discover Link Between Leaky Gut and 
Accelerated Biological Aging
Released: 23-Feb-2024 10:05 AM EST
Wistar Scientists Discover Link Between Leaky Gut and Accelerated Biological Aging
Wistar Institute

Wistar Institute’s Dr. Mohamed Abdel-Mohsen has demonstrated a connection between viral damage to the gut and premature biological aging.

Newswise: Chronic stress spreads cancer … here’s how
Released: 22-Feb-2024 8:05 PM EST
Chronic stress spreads cancer … here’s how
Cold Spring Harbor Laboratory

Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care.

Newswise: ‘Dynamic duo’ defenses in bacteria ward off viral threats
Released: 22-Feb-2024 8:05 PM EST
‘Dynamic duo’ defenses in bacteria ward off viral threats
University of Southampton

Scientists at the University of Southampton have discovered that bacteria can pair up their defense systems to create a formidable force, greater than the sum of its parts, to fight off attack from phage viruses.

Released: 22-Feb-2024 8:05 PM EST
A third of trans masculine individuals on testosterone ovulate
Amsterdam UMC

"Trans masculine people are people born female but do not identify as such, for example they feel male, gender fluid or non-binary. Our examination of their ovarian tissue shows that 33% of them show signs of recent ovulation, despite being on testosterone and no longer menstruating," says Joyce Asseler, PhD candidate at Amsterdam UMC.

Newswise: Study Reveals New Insights Into Immune System Role in Lung Cancer Risk
19-Feb-2024 10:05 AM EST
Study Reveals New Insights Into Immune System Role in Lung Cancer Risk
Mount Sinai Health System

Recent developments in cancer research have highlighted the vital role of the immune system, particularly in the notable successes of cancer immunotherapy. Now, a paradigm-shifting study led by researchers at the Icahn School of Medicine at Mount Sinai in New York in collaboration with the University of Helsinki and Massachusetts General Hospital sheds light on how variations in immune genetics influence lung cancer risk, potentially paving the way for enhanced prevention strategies and screening. The findings were described in the February 22 online issue of Science.

Released: 22-Feb-2024 11:05 AM EST
Immune Cell Receptor Provides Promising Immunotherapy Target
Johns Hopkins Medicine

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients’ immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

Released: 21-Feb-2024 3:05 PM EST
Snaking toward a universal antivenom
Scripps Research Institute

Scripps Research scientists discovered antibodies that protect against a host of lethal snake venoms.

   
19-Feb-2024 9:05 AM EST
Long COVID linked to persistently high levels of inflammatory protein: a potential biomarker and target for treatments
University of Cambridge

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

Newswise: Experimental compound kills cancer, spares immune cells
Released: 20-Feb-2024 10:05 AM EST
Experimental compound kills cancer, spares immune cells
UT Southwestern Medical Center

UT Southwestern Medical Center researchers have identified a compound that selectively eliminates cancer cells while sparing immune cells in a form of cell death known as ferroptosis. The findings, published in Science Translational Medicine, could lead to new treatments for a wide variety of cancer types, the study authors say.

Newswise: Study: Learning How Cells Dispose of Unwanted Materials is Key to Potential New Therapeutics
Released: 20-Feb-2024 9:05 AM EST
Study: Learning How Cells Dispose of Unwanted Materials is Key to Potential New Therapeutics
University of Nevada, Las Vegas (UNLV)

Are you sick and tired of getting sick and tired? A UNLV-led research team is exploring whether the reason we sometimes feel ill in the first place is because our body’s cells suffer from trash that accumulates within them.

   
Released: 19-Feb-2024 11:05 PM EST
Discovery about bacterial cell walls can lead to new antibiotics
Umea University

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls. This discovery could help develop new antibiotics against infectious diseases.

Newswise: Eating too much protein is bad for your arteries, and this amino acid is to blame
Released: 19-Feb-2024 8:05 PM EST
Eating too much protein is bad for your arteries, and this amino acid is to blame
University of Pittsburgh

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.

Released: 19-Feb-2024 3:05 PM EST
Moffitt Plays Pivotal Role in FDA Approval of Tumor-Infiltrating Lymphocyte Therapy for Advanced Melanoma
Moffitt Cancer Center

A first-of-its-kind cellular immunotherapy pioneered at Moffitt Cancer Center has received approval from the Food and Drug Administration and is now available for patients with advanced melanoma. Lifileucel is the first tumor-infiltrating lymphocyte therapy, or TIL, approved for solid tumors.

Released: 19-Feb-2024 11:05 AM EST
MSU researchers create more realistic synthetic human mini hearts, gain worldwide recognition
Michigan State University

Thanks to advancements in the development of patented synthetic human-like hearts first created at Michigan State, researchers can study human heart development and congenital heart disease on highly accurate models. This is facilitating the development of new therapies and pharmaceutical drugs to treat a variety of heart-related diseases just in time for the observance of American Heart Month in February.

Newswise: Bar-Ilan University researchers produce “laboratory testicles”
Released: 19-Feb-2024 3:05 AM EST
Bar-Ilan University researchers produce “laboratory testicles”
Bar-Ilan University

Dr. Nitzan Gonen, a Bar-Ilan University researcher specializing in the process of fetal sex determination, together with research students Aviya Stopel, Cheli Lev and Stav Dahari, has succeeded in creating "laboratory testicles" that may significantly advance understanding of the mechanisms involved in sex determination and provide solutions for male infertility, which affects one in 12 men worldwide.

   
Newswise: Brain waves are part of memory
Released: 16-Feb-2024 9:05 PM EST
Brain waves are part of memory
Universitätsklinikum Bonn

Neuroscientists from Bonn, New York, and Freiburg discover interactions between so-called "ripples" and nerve cells during human memory processes.

Newswise: Promising target for CAR T-cell therapy leads to potent antitumor responses against cutaneous and rare melanomas
Released: 16-Feb-2024 10:05 AM EST
Promising target for CAR T-cell therapy leads to potent antitumor responses against cutaneous and rare melanomas
University of California, Los Angeles (UCLA), Health Sciences

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.

Newswise: Ancient retroviruses played a key role in the evolution of vertebrate brains
Released: 15-Feb-2024 8:05 PM EST
Ancient retroviruses played a key role in the evolution of vertebrate brains
Cell Press

Researchers report in the journal Cell that ancient viruses may be to thank for myelin—and, by extension, our large, complex brains.

Released: 15-Feb-2024 3:05 PM EST
Alerta do especialista: saúde e células zumbi durante o envelhecimento
Mayo Clinic

Com o avanço da idade, as células podem sofrer envelhecimento, um estado no qual elas param de crescer, mas continuam liberando moléculas inflamatórias e tecido degradado.

Released: 15-Feb-2024 3:05 PM EST
تحذير خبراء: خلايا الصحة والخلايا الزُومبيّ في الشيخوخة
Mayo Clinic

مدينة روتشستر، ولاية مينيسوتا —مع تقدم السن، يمكن أن تتعرض الخلايا للشَيخُوخَة، وهي حالة تتوقف فيها عن النمو ولكنها تستمر في إطلاق جزيئات التهابية وجزيئات مدمرة للأنسجة. عندما يكون الشخص صغيرًا في السن، يستجيب الجهاز المناعي ويطرح الخلايا الهَرِمة، والتي يشار إليها غالبًا باسم الخلايا الزُومبيّ. ومع ذلك، تبقى خلايا الزُومبيّ باقية وتساهم في العديد من المشاكل والأمراض الصحية المرتبطة بالعمر. سلط الباحثون في مايو كلينك، في دراستين، الضوء على بَيولُوجْيا خلايا الشَيخُوخَة.

Released: 15-Feb-2024 11:05 AM EST
Do sugar-free candy and gum give you gas? Researchers think they know why
UC Davis Health

Scientists at the UC Davis School of Medicine may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other products.

Newswise: Nanomedicine paves the way for new treatments for spinal cord injury
Released: 14-Feb-2024 10:05 PM EST
Nanomedicine paves the way for new treatments for spinal cord injury
Politecnico di Milano

A Study by Politecnico di Milano and Istituto Mario Negri has been published in Advanced Materials.

Newswise: Wound-homing molecule accelerates tissue repair
Released: 14-Feb-2024 10:05 PM EST
Wound-homing molecule accelerates tissue repair
Tampere University

One of the key goals of medical science is to speed up the healing of tissue injuries in a way that would not enable the forming of less functional scar tissue in the affected areas.

Newswise: Discovery of a subset of human short introns that are spliced out by a novel mechanism
Released: 14-Feb-2024 10:05 PM EST
Discovery of a subset of human short introns that are spliced out by a novel mechanism
Fujita Health University

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

Newswise: Pancreatic cancer hijacks a brain-building protein
Released: 14-Feb-2024 10:05 PM EST
Pancreatic cancer hijacks a brain-building protein
Cold Spring Harbor Laboratory

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research—eight years in the making.

Newswise: By growing animal cells in rice grains, scientists dish up hybrid food
Released: 14-Feb-2024 9:05 PM EST
By growing animal cells in rice grains, scientists dish up hybrid food
Cell Press

From lab-grown chicken to cricket-derived protein, these innovative alternatives offer hope for a planet struggling with the environmental and ethical impacts of industrial agriculture.

Newswise: Male fertility gene discovery reveals path to success for sperm
Released: 14-Feb-2024 7:05 PM EST
Male fertility gene discovery reveals path to success for sperm
University of Edinburgh

The discovery of a pair of genes that work in perfect harmony to protect male fertility, could provide new insights into some unexplained cases of the most severe form of infertility, research suggests.

Released: 14-Feb-2024 1:05 PM EST
Key genes linked to DNA damage and human disease uncovered
Wellcome Trust Sanger Institute

Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.

Newswise: Seminal Study Sheds Light on Cell Mitochondria
Released: 14-Feb-2024 1:05 PM EST
Seminal Study Sheds Light on Cell Mitochondria
Stony Brook University

A collaborative effort led by Stuti Sharma, PhD, Assistant Professor in the Department of Biochemistry & Cell Biology at Stony Brook University, resulted in a promising study toward a better understanding of mitochondrial adenosine triphosphate (ATP) synthase.



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