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Human Stem Cell Model Reveals Molecular Cues Critical to Neurovascular Unit Formation

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Using human embryonic stem cells, researchers at University of California, San Diego School of Medicine and Moores Cancer Center and Sanford-Burnham Medical Research Institute created a model that allows them to track cellular behavior during the earliest stages of human development in real-time. The model reveals, for the first time, how autonomic neurons and blood vessels come together to form the neurovascular unit.

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Researchers Watch Protein 'Quake' after Chemical Bond Break

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Scientists for the first time have precisely measured a protein’s natural “knee-jerk” reaction to the breaking of a chemical bond – a quaking motion that propagated through the protein at the speed of sound.

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Blood to Feeling: McMaster Scientists Turn Blood Into Neural Cells

Stem cell scientists at McMaster can now directly convert adult human blood cells to both central nervous system (brain and spinal cord) neurons as well as neurons in the peripheral nervous system (rest of the body) that are responsible for pain, temperature and itch perception. This means that how a person’s nervous system cells react and respond to stimuli, can be determined from his blood.

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Trending Stories Report for 21 May 2015

Trending news releases with the most views in a single day. Topics include: gun regulation, psychology and altruism, big data, threats to coral reefs, extra-terrestrial life, personalized diets, metabolic syndrome and heart health, new drug target to treat arthritis, and archeologists find oldest tools.

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Scientists Discover Origins of the Lymphatic System

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In a first, the Weizmann Institute’s Dr. Karina Yaniv and a team of scientists have determined how the lymphatic system develops in the embryo … and grown lymphatic cells in the lab. Using zebrafish, they showed that the cells originate in a vein niche that harbors angioblasts. Besides solving this century-old puzzle, their work can shed light on disease.

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Pilot Clinical Trial Finds Injected Immune Cells Safe in Multiple Myeloma Patients

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients’ own bone marrow to treat multiple myeloma, a cancer of white blood cells.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 26-May-2015 12:00 PM EDT

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What Makes Cancer Cells Spread? New Device Offers Clues

Why do some cancer cells break away from a tumor and travel to distant parts of the body? A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.

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Southampton Scientists Identify Crucial Step in Helping to Prevent Hepatitis C Virus Replicating

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New research from the University of Southampton has identified how changes in the cell membrane play a pivotal role in how the Hepatitis C virus replicates.

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How the Immune System Controls the Human Biological Clock in Times of Infection

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases, discovered collaborators. They report how a critical white blood cell, when exposed to bacteria, makes the biological clock inside the macrophage stop, allowing it to become inflamed.