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A reporter's PressPass is required to access this story until the embargo expires on 6-Aug-2015 12:00 PM EDT

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A reporter's PressPass is required to access this story until the embargo expires on 6-Aug-2015 12:00 PM EDT

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A reporter's PressPass is required to access this story until the embargo expires on 3-Aug-2015 11:00 AM EDT

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Identifying a Key Growth Factor in Cell Proliferation

In two companion papers published in Cell, researchers from MIT's Koch Institute reveal why proliferating cells — including those in tumors — require mitochondrial respiration. While there are other ways to make ATP, cells can’t proliferate without access to electron acceptors provided by respiration.

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Newly Identified Mechanism of p53-Induced Cell Death Could Aid Cancer Therapy

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Research led by St. Jude Children’s Research Hospital reveals how the tumor suppressor protein p53 works in the cytoplasm to trigger death via apoptosis and identifies a potential cancer treatment strategy.

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Genetic Tug of War in the Brain Influences Behavior

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Researchers at the University of Utah School of Medicine report that a nuanced, targeted version of parental control over gene expression, is the method of choice over classic genomic imprinting. Published in Cell Reports, so-called noncanonical imprinting is particularly prevalent in the brain, and skews the genetic message in subpopulations of cells so that mom, or dad, has a stronger say. The mechanism can influence offspring behavior, and because it is observed more frequently than classic imprinting, appears to be preferred.

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Evolutionary War Between Microorganisms Affecting Human Health, IU Biologist Says

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Health experts have warned for years that the overuse of antibiotics is creating “superbugs” able to resist drugs treating infection. Now scientists at Indiana University and elsewhere are finding evidence that an invisible war between microorganisms may also be catching humans in the crossfire.

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Researchers Design First Artificial Ribosome

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Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell.

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Next Generation Gene Therapy for Fanconi Anemia Disorder Using CRISPR-Cas9 Gene Editing Technology–-Does This Approach Open Doors for Treating Other Rare Diseases?

Jakub Tolar, M.D., Ph.D., discusses how gene therapy, specifically gene editing technology called CRISPR-Cas9 signals hope for Fanconi anemia and other blood diseases.

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Researchers Illuminate Key Role of NOX Proteins in Liver Disease

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Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.