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Structure of World’s Largest Single Cell Is Reflected at the Molecular Level

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Daniel Chitwood, Ph.D., assistant member, used the world’s largest single-celled organism, an aquatic alga called Caulerpa taxifolia, to study the nature of structure and form in plants. It was recently reported the results of their work in the online journal, PLOS Genetics.

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X-Ray Study Reveals Division of Labor in Cell Health Protein

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Researchers working in part at the Department of Energy’s SLAC National Accelerator Laboratory have discovered that a key protein for cell health, which has recently been linked to diabetes, cancer and other diseases, can multitask by having two identical protein parts divide labor.

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Cell Mechanism Discovered That May Cause Pancreatic Cancer

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Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have found that defects in how cells are squeezed out of overcrowded tissue to die, a process called extrusion, may be a mechanism by which pancreatic cancer begins. From these findings, they may have identified an effective way to reverse the defective extrusion’s effects without destroying normal tissues nearby. The results were published in the latest edition of the journal eLife.

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Research Implicates Metabolic Process of the Liver in the Spread of Colorectal Cancer

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Colorectal cancer is a cancer on the move: about 50 percent of patients with the disease see their cancer spread, typically to the liver. By identifying genes that become activated in cancer cells that successfully travel — metastasize — to the liver, researchers at Rockefeller have implicated metabolic processes within the liver as a possible means by which starving transient cancer cells can go on to form deadly new colonies.

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Scientists Establish that Drug Candidates Can Block Pathway Associated with Cell Death in Parkinson’s Disease

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In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 5-Feb-2015 12:00 PM EST

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UK Researchers Solve Metabolic Mystery Lending Insight Into Lafora Disease

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Researchers at the University of Kentucky have unlocked the metabolic function of the essential enzyme laforin, which opens new pathways to treating the deadly Lafora's Disease.

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Scientists Identify New Mechanism to Aid Cells Under Stress

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A team of biologists has identified new details in a cellular mechanism that serves as a defense against stress. The findings potentially offer insights into tumor progression and neurodegenerative diseases, such as Parkinson’s and Alzheimer’s — the cell’s inability to respond to stress is a major cause of these diseases.

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Cells Take Sole Responsibility for Merkel Cell Maintenance

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Researchers have identified a population of “progenitor” cells in the skin that are solely responsible for the generation and maintenance of touch-sensing Merkel cells.

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New Study by UC San Diego Questions Targeting Protein Kinase C as a Cancer Treatment

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