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Carnival Game Mimics Eye Growth

The motion of coins in a “Penny Pusher” carnival game is similar to the movement of cells in the eye’s lens, as described in a new study published in Investigative Ophthalmology & Visual Science (IOVS). This new insight may help scientists understand how the eye maintains its precise shape — critical for clear vision — and how cataracts develop.

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Protein Shake-Up

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A certain class of proteins has challenged researchers’ conventional notion that proteins have a static and well-defined structure.

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Control Switch That Modulates Cell Stress Response May Be Key to Multiple Diseases

Researchers at the University of California, San Diego School of Medicine have discovered a control switch for the unfolded protein response (UPR), a cellular stress relief mechanism drawing major scientific interest because of its role in cancer, diabetes, inflammatory disorders and several neural degenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS).

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 30-Mar-2015 9:00 AM EDT

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 29-Mar-2015 12:05 PM EDT

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 1-Apr-2015 12:30 PM EDT

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Immunomagnetic Assay On-a-Chip Captures, Analyzes Circulating Tumor Cells

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Dartmouth bioengineers demonstrate a novel system that couples nano-engineered particles and microfluidic chips for capturing and manipulating circulating tumor cells.

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Brain Tumor Cells Decimated by Mitochondrial "Smart Bomb"

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An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.

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Researchers Discover Mechanism to Control Multiple Processes of Cell Growth, Division

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Investigators from Dartmouth's Norris Cotton Cancer Center find that the protein Pom1 possesses the ability to modify different sets of proteins to coordinate the processes of cell growth and division.

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Stress Granules Ease the Way for Cancer Metastasis

Tumors that produce more stress granules are more likely to metastasize, according to researchers in Canada. The results suggest that drugs to inhibit the formation of these structures might rein in cancer metastasis.