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Microbes in Central Park Soil: If They Can Make It There, They Can Make It Anywhere

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Researchers led by Colorado State University uncovered more than 167,000 kinds of bacteria, archaea and eukaryotes in the soil beneath one of the nation's iconic urban environments. That’s 260 times as many species of birds, plants and invertebrates that live in the Park - combined.

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Disease Decoded: Gene Mutation May Lead to Development of New Cancer Drugs

The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly

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Modified Vitamin D Shows Promise as Treatment for Pancreatic Cancer

Salk scientists find that a vitamin D-derivative makes tumors vulnerable to chemotherapy.

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Strategic or Random? How the Brain Chooses

Scientists at the Howard Hughes Medical Institute's Janelia Research Campus have shown that the brain can temporarily disconnect information about past experience from decision-making circuits, thereby triggering random behavior.

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New Protein Players Found in Key Disease-Related Metabolic Pathway

Cells rely on the mechanistic target of rapamycin complex 1 (mTORC1) pathway—which senses the availability of nutrients—to coordinate their growth with existing environmental conditions. The lab of Whitehead Member David Sabatini has identified a family of proteins that negatively regulate the branch upstream of mTORC1 that senses amino acids, the building blocks of proteins.

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Surprising Diversity of Antibody Family Provides Clues for HIV Vaccine Design

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Scientists at The Scripps Research Institute (TSRI) have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings provide clues for the design of a future HIV vaccine.

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New Technique Reveals a Role for Histones in Cell Division

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Proteins known as histones give structure to DNA, which coils around them like string on spools. But as is so often the case in biology, it turns out there is more to these structures than meets the eye.

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Why Do Leaves Change Color in the Fall? (Video)

It’s the first day of autumn, and the telltale signs are here: crisp weather, pumpkin spice lattes and, most importantly, the leaves are changing colors. Ever wonder why some leaves turn red, others yellow and some just turn brown? We’ll tell you all about the chemistry behind this seasonal spectacle in the latest Reactions episode.

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Singapore Researchers Discover a Gene That Increases Incidence of Acute Myelogenous Leukaemia

A novel study by the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) found that an increase in a gene known as Leo1 affects other genes that are directly implicated in acute myelogenous leukaemia (AML), increasing the incidence of cancer.

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Cancer Cells Adapt Energy Needs to Spread Illness to Other Organs

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Scientists at The University of Texas MD Anderson Cancer Center have found that cancer cells traveling to other sites have different energy needs from their “stay-at-home” siblings which continue to proliferate at the original tumor site.

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