Feature Channels: Stem Cells

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Biofilms are highly resistant communities of bacteria that pose a major challenge in the treatment of infections.

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Heterotopic ossification (HO), a pathological condition characterized by abnormal bone formation in soft tissues, can result from traumatic injuries like fractures and surgeries such as hip arthroplasty. The underlying cellular mechanisms and specific cell phenotypes driving this process remain poorly understood due to the complex heterogeneity of the involved progenitor cells.

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Research from Ann & Robert H. Lurie Children’s Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn’s disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

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Support for early career researchers is about to get a major boost, thanks to a new fellowship fund established by leaders at La Jolla Institute for Immunology (LJI) and Japan-based global pharmaceutical corporation, Kyowa Kirin, Inc.

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After the successful treatment, a patient shares his story to inspire others.

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In a step forward in the development of genetic medicines, researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body. If translated into the clinic, this approach could expand access and reduce the cost of gene therapies for blood disorders, many of which currently require patients receive chemotherapy and a stem cell transplant. The findings were published today in the journal Science.

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UC San Diego Health is among the first in the nation to perform an experimental regenerative brain cell therapy for epilepsy aimed at eliminating seizures.

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UT Southwestern Medical Center biologists have developed a new stem cell-based embryo model for studying early human development, tissue formation, and differentiation, offering valuable contributions to the field of developmental biology and regenerative medicine.

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Researchers at the University of Illinois Chicago have identified a process by which enzymes can help prevent heart damage in chemotherapy patients