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Medicine

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Tumors, Northwestern Medicine, Pediatrics, Pediatric Brain Tumor, Robert H. Lurie Comprehensive Cancer Center of Northwestern University

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Medicine

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Health Policy, Affordable Care Act , Medicaid, Medicaid Coverage, JAMA Internal Medicine, Penn Medicine, Health Economics, Primary Care Physicians

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Medicine

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Alzheimer's, Mild Cognitive Impairment, Genetic Test, Pharmacogenetics

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Alzheimer’s Drug Prescribed ‘Off-Label’ for Mild Cognitive Impairment Could Pose Risk for Some

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Donepezil, a medication that is approved to treat people with Alzheimer’s disease, should not be prescribed for people with mild cognitive impairment without a genetic test.

Medicine

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Immunotherapy, adoptive t cell transfer, Cancer, Metastatic Melanoma, T Cell, Immune Cells

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Novel ‘Barcode’ Tracking of T Cells in Immunotherapy Patients Identifies Likely Cancer-Killers

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A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person’s immune system are best suited to fight cancer. The findings will be published February 24 in Science Immunology.

Science

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Finding of 38,000 Year-Old Engravings Confirms Ancient Origins of Technique Used by Seurat, Van Gogh, Pissarro, and Lichtenstein

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A newly discovered trove of 16 engraved and otherwise modified limestone blocks, created 38,000 years ago, confirms the ancient origins of the pointillist techniques later adopted by 19th and 20th century artists such as Georges Seurat, Vincent Van Gogh, Camille Pissarro, and Roy Lichtenstein.

Medicine

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antibiotic resisistance, Pediatric Infectious Disease, Enterobacteriaceae, antibiotic usage, Antibiotics, Pediatrics

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Antibiotic Resistance: A Burgeoning Problem for Kids Too

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In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These antibiotic resistant infections are in turn linked to longer hospital stays and potentially greater risk of death.

Science

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Evolution, South America, Brazil, genetic, Paleoamerican, Ancient Human

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Study Shows Ancient Humans Arrived in South America in Multiple Waves

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The findings published Wednesday (Feb. 22, 2017) in the journal Science Advances suggest that Paleoamericans share a last common ancestor with modern native South Americans outside, rather than inside, the Americas and underscore the importance of looking at both genetic and morphological evidence, each revealing different aspects of the human story, to help unravel our species’ history.

Science

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Dna Vaccine, Immune Tolerance, Leukemia, neo antigen, WT1

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A Novel DNA Vaccine Design Improves Chances of Inducing Anti-Tumor Immunity

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Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets.

Medicine

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Genetics, ophthalmolgy, coloboma, Blindness, Deafness, Waardenburg syndrome, Children, National Eye Institute (NEI), National Institutes Of Health (NIH), Albinism, Genetic Testing

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Media Availability: NIH Scientists Identify Disorder Causing Blindness, Deafness, Albinism and Fragile Bones

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Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have identified the genetic underpinnings of a rare disorder that causes children to be born with deafness, blindness, albinism and fragile bones.

Science

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Plant Stress, Iowa State University, Drought

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Iowa State University Researchers Detail Genetic Mechanisms That Govern Growth and Drought Response in Plants

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New Iowa State University research outlines how the genetic pathways that govern growth and stress response in plants sometimes clash. The research could lead to better performing crop varieties.

Medicine

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Liver, Liver Enzymes, Blood Test, Pathology, Hepatology, Gastroenterology, Electronic Health Record

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A reporter's PressPass is required to access this story until the embargo expires on 2-Mar-2017 12:05 AM EST

Medicine

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pain, IASP, Chronic Pain, Older Adults, Physical Activity, Pain prevention, central nervous system, Activity level

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Can Staying Active Help to Prevent Chronic Pain? Physical Activity Affects Pain Modulation in Older Adults

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Older adults with higher levels of physical activity have pain modulation patterns that might help lower their risk of developing chronic pain, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published by Wolters Kluwer.

Medicine

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Kidney Transplant

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 2-Mar-2017 5:00 PM EST

Medicine

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Kidney Damage Diagnosis May Be Inaccurate for Many, Suggests Study

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An analysis of patient records reveals that, for many, an initial diagnosis of “acute kidney injury” using current clinical diagnostic methods may have been inaccurate.

Science

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doublesex, Genetics, sexual differentiation, evolutionary development, Evolution, sexual traits, Entomology, Insects, Beetles, Biology, evodevo, dsx, Sexual Development

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Feb-2017 5:00 AM EST

Science

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Environment, Sustainability, Recycling, Polymers

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New Polymer Additive Could Revolutionize Plastics Recycling

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Only 2 percent of the 78 million tons of manufactured plastics are currently recycled into similar products because polyethylene (PE) and polypropylene (PP), which account for two-thirds of the world’s plastics, have different chemical structures and cannot be efficiently repurposed together. That could all change with a discovery by a Cornell University research team. In this video, Geoffrey Coates, a professor of chemistry and chemical biology at Cornell University, explains how his research team created a new, multiblock polymer that, when added in small measure to a mix of the two otherwise incompatible materials, creates a new and mechanically tough polymer. Not only does this tetrablock polymer show promise for improving recycling, it could spawn a whole new class of mechanically tough polymer blends.

Medicine

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Microbiology, Fungus, antibacterial resistance

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First Systematic Study of Deadly, Antibiotic-Resistant Fungus Reported

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The deadly fungus, Candida auris, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected. Now, in a first-of-its-kind study, microbiologists at Case Western Reserve University School of Medicine have provided previously uninvestigated details pertaining to C. auris drug resistance and growth patterns.

Science

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Biological and Environmental Research, biological and environmental sciences, Biology, brown rot, Fungi, Fungus, wood, Biofuel, Biofuel Production, genetic, Genetics, postia placenta, Proceedings Of The Natinal Academy Of Sciences, Proceedings of the National Academy of Science, PNAS, Decay, wood rot, wood decay, University of Minnesota, Environmental Molecu

The Brown Rot Two-Step

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Understanding how brown rot fungi degrade wood could lead to new tools for more efficient biofuel production.

Medicine

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HIV, Transplantation

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HIV+ Kidney Failure Patients Face Hurdles in Receiving Necessary Transplants

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• From 2001 to 2012, HIV+ kidney failure patients on the transplant waiting list were 28% less likely to receive a transplant compared with their HIV- counterparts. • They were half as likely to receive a kidney from a living donor.

Medicine

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Amyloid, Amyloid Fibrils, Fibrils, Staphylococcus Aureus, Staphylococcus Aureus (Mrsa), Staphylococcus, MRSA, antibiotic resisistance, Antibiotics

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Novel Amyloid Structure Could Lead to New Types of Antibiotics

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Researchers have discovered unique amyloid fibers used by the highly drug resistant Staphylococcus aureus bacterium (which causes MRSA). The findings could lead to new types of antibiotics with a novel mechanism of action for attacking bacterial toxins.







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