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Genetic Test Helps Predict Which Children with Kidney Disease Will Respond to Standard Therapy

• Among children with sporadic nephrotic syndrome, genetic mutations in the kidney’s filtration barrier were frequently linked with a lack of response to immunosuppressive treatments. • The genetic test was even more predictive than a kidney biopsy for identifying children who would not benefit from immunosuppressive therapies.

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Ferric Citrate May Reduce Dialysis Patients’ Need for Multiple Medications

• Ferric citrate effectively reduced blood phosphorus levels while increasing iron stores and decreasing the need for intravenous iron and anemia medications in dialysis patients. • The medication may help reduce complications and costs associated with kidney disease care.

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Zerenex™ (Ferric Citrate) Long-Term Phase 3 Study Results Published in the Journal of the American Society of Nephrology

Keryx Biopharmaceuticals, Inc. announced the publication of results from the long-term, randomized, active control Phase 3 study of Zerenex (ferric citrate), the Company's investigational oral ferric iron-based phosphate binder, for the treatment of hyperphosphatemia in patients with end-stage renal disease (ESRD) on dialysis. The PERFECTED study (PhosphatE binding and iRon delivery with FErric CiTrate in EsrD) was published online today in the Journal of the American Society of Nephrology (JASN).

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Scientists Discover Genetic Switch That Can Prevent Peripheral Vascular Disease in Mice

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Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation.

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New Imaging Agent Provides Better Picture of the Gut

A multi-institutional team of researchers has developed a new nanoscale agent for imaging the gastrointestinal (GI) tract. This safe, noninvasive method for assessing the function and properties of the GI tract in real time could lead to better diagnosis and treatment of gut diseases.

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Social and Behavioral Sciences

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Study Shows Role of Media in Sharing Life Events

To share is human. And the means to share personal news — good and bad — have exploded over the last decade, particularly social media and texting. But until now, all research about what is known as “social sharing,” or the act of telling others about the important events in our lives, has been restricted to face-to-face interactions.

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Inadequate Mental Health Care for Blacks with Depression and Diabetes, High Blood Pressure

A new study in General Hospital Psychiatry confirms that Blacks with depression plus another chronic medical condition, such as Type 2 diabetes or high blood pressure, do not receive adequate mental health treatment.

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ORNL Study Reveals New Characteristics of Complex Oxide Surfaces

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A combination of microscopy and data processing has given researchers an unprecedented look at the surface of a material known for its unusual physical and electrochemical properties.

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Atomic Structure of Key Muscle Component Revealed in Penn Study

Adding to the growing fundamental understanding of the machinery of muscle cells, biophysicists describe in minute detail actin filaments are stabilized at one of their ends to form a basic muscle structure called the sarcomere.

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Farmers Market Vouchers May Boost Produce Consumption in Low-Income Families

Vouchers to buy fresh fruits and vegetables at farmers markets increase the amount of produce in the diets of some families on food assistance, according to research led by NYU’s Steinhardt School of Culture, Education, and Human Development.

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