Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.
We all know that communication encompasses so much more than words. Facial expressions, intonations, hand gestures, and more contribute to our expressiveness. However, in social media, these intricacies are lost.
New Fossil Bovids from Kromdraai shed light on South Africa's ancient ecosystems.
A groundbreaking multicenter cohort study in China has illuminated the impact of sex on the outcomes of liver transplantation (LT) for hepatocellular carcinoma (HCC), the most common type of liver cancer.
The US is experiencing dual overlapping public health crises of drug poisoning (herein, drugs) and firearm deaths. Since 1999, more than 1 million residents of the US have died by fatal drug poisonings and more than 750 000 by firearms.
A new study reveals a groundbreaking approach to immunotherapy, demonstrating that blocking the interaction between the CD300A receptor and phosphatidylserine (PS) significantly enhances the ability of human natural killer (NK) cells to lyse hematologic malignancies (HMs).
A new study led by the University of Portsmouth in England has developed an innovative method to customise and strengthen DNA origami structures, which could lead to advances in medicine, biotechnology, and beyond.
With the development of genome sequencing technologies, many long non-coding RNAs (lncRNAs) have been identified in fruit and vegetables.
After a century of functional extinction on the Australian mainland, a Flat oyster reef has been successfully restored along a metropolitan Adelaide coastline.
A new Lancet Oncology article describes how climate-driven risks in the Caribbean negatively affect every step in the cancer control continuum, from etiology to survivorship.
Researchers leading a national dialogue about parental burnout from The Ohio State University College of Nursing and the university’s Office of the Chief Wellness Officer found that pressure to try to be “perfect” leads to unhealthy impacts on both parents and their children.
Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a study published in the May 8, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
How a non-invasive technique temporarily opened the blood-brain barrier to deliver an immunotherapy drug to the brain in a large animal study.
Researchers used advanced computing techniques to engineer the bacteria Pseudomonas putida to optimize its production of isoprenol using carbon from plant material. Isoprenol has a potential role in the production of jet biofuel blendstocks.
Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors—an advance that could transform cancer treatment. The promising findings, reported today in Science Advances, involve CAR-T cell therapy, which supercharges the immune system to identify and attack cancer cells.
A study that used artificial intelligence (AI) and social media posts to assess the rates of depression and anxiety in nearly half of American counties found that the AI-generated measurements produced more reliable assessments than population surveys. The findings are published in Nature Digital Medicine.
Spina bifida is the most common structural disorder of the human nervous system. The causes are largely unknown, but University of California San Diego researchers led a study that points to a link involving a chromosomal microdeletion — and also underscores the value of folic acid as a preventive measure.
Many parents ponder why one of their children seems more emotionally troubled than the others. A new study in the United Kingdom reveals a possible basis for those differences.
The May issue of The American Journal of Gastroenterology highlights new clinical science and reviews on hepatic encephalopathy management using a smartphone app’s artificial intelligence, cyclic vomiting syndrome prevalence and incidence, alcohol-associated liver disease and alcohol use disorder in young women, and polypectomy technique.
ChatGPT, the artificial intelligence (AI) chatbot designed to assist with language-based tasks, can effectively extract data for research purposes from physicians' clinical notes, UT Southwestern Medical Center researchers report in a new study. Their findings, published in NPJ Digital Medicine, could significantly accelerate clinical research and lead to new innovations in computerized clinical decision-making aids.
These days, detecting a planetary atmosphere tens or even hundreds of light-years from Earth might not sound like such a big deal. Scientists have found signs of atmosphere surrounding dozens of exoplanets over the past two decades.
In a groundbreaking study published May 2, 2024 in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder.
Local decision-makers looking for ways to reduce the impact of heat waves on their communities have a valuable new capability at their disposal: a new study on vegetation resilience.
In a groundbreaking development for addressing future viral pandemics, a multi-institutional team involving Lawrence Livermore National Laboratory researchers has successfully combined an artificial intelligence-backed platform with supercomputing to redesign and restore the effectiveness of antibodies whose ability to fight viruses has been compromised by viral evolution. The work was published in the journal Nature.
Researchers at the Icahn School of Medicine at Mount Sinai have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to produce potential therapeutic effects in patients with neuropsychiatric disorders such as depression and anxiety.
Researchers from the University of California, Irvine have found evidence of the molecular causes of the damaging impact heat stress causes on the gut, liver and brain in the elderly. These findings point to the potential of developing precise prognostic and therapeutic interventions.
When low-income entrepreneurs start their own businesses, they frequently fear failure — a well-documented phenomenon. But over time, they may also fear success, given the costs and unknowns it can bring, and this barrier to growth is under-studied and underappreciated. A new study from a Keough School of Global Affairs expert breaks new ground by explaining this fear and offers five recommendations to help entrepreneurs overcome it and move out of poverty.
Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings, recently published in Circulation, could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.
In a study in ACS Nano, researchers describe swarms of microscale robots (microrobots) that captured bits of plastic and bacteria from water. Afterward, the bots were decontaminated and reused.
UCLA Health researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and where Alzheimer’s disease begins.
GP data can provide unique insights into common health conditions, new research looking at insomnia symptom prevalence in England has shown. The University of Bristol-led study, published in BMJ Open today [8 May], also highlights the value of improving access to this data for future health research.
In lab experiments, engineers at CU Boulder asked groups of younger and older adults to complete a deceptively simple task: to reach for a target on a computer screen. The group's findings could one day help doctors diagnose a range of illnesses, from Parkinson's disease to mental health conditions like depression.
Researchers led by CU Boulder primatologist Michelle Sauther walked the paths of the Lajuma Research Centre in South Africa at night, keeping an eye out for the glowing eyes of galago primates, or bushbabies. The team's findings reveal troubling hints about how small animals may adapt to extreme temperatures.
A new international research project showed that intervention with mobile vaccination teams in Sierra Leone is an effective way of reaching rural populations to increase COVID-19 vaccination rates.
A team of scientists, with help from Argonne National Laboratory’s Advanced Photon Source, have demonstrated the existence of an elusive state of matter known as quantum spin nematic.
Under DOE’s Integrated Research Infrastructure initiative, a team from ORNL and SLAC is establishing a data portal that will enable Frontier to process the results from experiments conducted by LCLS-II.
A brief roundup of news and story ideas from the experts at UCLA Health.
Computational scientists at the Department of Energy’s Oak Ridge National Laboratory have published a study in the Journal of Chemical Theory and Computation that questions a long-accepted factor in simulating the molecular dynamics of water: the 2 femtosecond (one quadrillionth of a second) time step.
The discovery opens doors to better stem cell therapies.
A new study of entrepreneurial small businesses created to address poverty in rural Africa found that the introduction of the entrepreneurial model led to unexpected social shifts that made the small business operators a source of friction and social discontent in their communities.
Understanding how mucus changes, and what it changes in response to, can help diagnose illnesses and develop treatments. In APL Bioengineering, researchers develop a system to grow mucus-producing intestinal cells and study the characteristics of the mucus in different conditions.
In APL Bioengineering, researchers used a breast cancer cell line panel and primary tumor explants from breast and cervical cancer patients to examine two different cellular contractility modes: one that generates collective tissue surface tension that keeps cell clusters compact and another, more directional, contractility that enables cells to pull themselves into the extracellular matrix.
Researchers have developed a comprehensive statistical theory for analyzing the proton-induced Lithium-6 (Li) reaction, significantly enhancing our understanding of light nucleus reactions.
Total knee replacements performed with the help of a surgical robot have better outcomes on average than similar surgeries performed manually but can cost significantly more, a new study by UT Southwestern Medical Center researchers shows. T
A recent review article provides critical insights into the management of acute agitation in reproductive-age females and during pregnancy within the emergency departments (EDs).
A study has outlined the critical needs and essential technologies for a Low Earth Orbit (LEO) constellation to augment satellite navigation systems, significantly improving the Positioning, Navigation and Timing (PNT) services.
“The independent research groups, led by Prof. Scott W. Lowe and Christina Curtis,respectively, have uncovered a similar definitive pathway in the progression of gastric cancer (GC) initiated with loss of the TP53 gene, representing a milstone in understanding the early stages of this deadly disease”. Dr. Zhaocai Zhou, head of a GC laboratory from Fudan University, stated.
Rural Americans are less likely to initiate care for substance use disorders and to receive ongoing care compared with those who live in urban areas. When they do access care, people who live in less populated areas are more likely to have to go outside their provider network to receive treatment, which comes with higher out-of-pocket costs.
Researchers at the UNC Eshelman School of Pharmacy and the UNC School of Medicine have engineered a probiotic yeast that enhances probiotic absorption in the gut and has the ability to suppress and even reverse inflammation in animals.
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