New Insights into Intervertebral Disc Degeneration: Role of Oxygen Concentration and HIF1A in Nucleus Pulposus Cells
Chinese Academy of SciencesLower back pain, primarily caused by IDD, poses a tremendous societal challenge. Current treatment strategies for IDD fall short in restoring the original function of the intervertebral disc. The research team focused on physiological hypoxia, a characteristic of the nucleus pulposus, due to its unique anatomical configuration.