Protein purification is a multibillion-dollar industry. A new purification process developed by Michigan Tech biochemists, called capture and release (CaRe), is a lot like catch and release fishing. It comes down to the picking the right lure to bait a specific protein and CaRe speeds up protein purification while also lowering costs.
University of Colorado Cancer Center study shows healthy form of the leukemia-causing gene MLL may push pluripotent stem cells (which have proven difficult to use in human patients) to become durable hematopoietic stem cells (which are usable in patients, but have until now been impossible to make).
Genetically engineered mosquitoes are resistant to multiple types of dengue virus (DENV), according to a study published January 16 in the open-access journal PLOS Pathogens by Prasad Paradkar of the Australian Animal Health Laboratory, and Omar Akbari of the University of California, San Diego, and colleagues. As noted by the authors, this is the first engineered approach that targets all types of DENV, which is crucial for effective disease suppression.
Researchers studying proteins in heart cells have unexpectedly discovered that a common microscopy fluorescent protein carries reversible photobleaching properties. This phenomenon may lead to inaccurate or unreliable data.
Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink brain cancer stem cells.
A team of physicists from McMaster University has developed a process to modify red blood cells so they can be used to distribute drugs throughout the body, which could specifically target infections or treat catastrophic diseases such as cancer or Alzheimer’s.
A research group from the Biodiversity Unit of the University of Turku studies the diversity of parasitoid insects around the world.
A large, multicenter study led by researchers at Children’s Hospital of Philadelphia (CHOP) compared the genomic data of more than 100,000 people of European ancestry and discovered how relatively rare, albeit recurrent, genetic variations can influence a variety of common diseases. In addition, existing drugs could be repurposed to target these conditions – ranging from autoimmune diseases to neuropsychological diseases and even cancer – now that the genetic underpinnings of these conditions are known.
Researchers at University of California San Diego have discovered that when certain microbes pair up, stunning floral patterns emerge.
A team of researchers from the National University of Singapore has developed a personalised assessment tool which can detect the incidence of cancer, predict patient survivability and determine patient suitability for immunotherapy cancer treatment.
What's your type? That question could gain new meaning, thanks to scientists who've categorized how humans age into different classes dubbed "ageotypes," reports a new study from the Stanford University School of Medicine.
A lab accident produced a monster of a polymer brush, an emerging biocompatible material that staves off bacteria while coating and lubricating.
Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer’s disease, by combining computational methods and lab research.
Researchers have devised a straightforward technique for building a laboratory device known as an electroporator – which applies a jolt of electricity to temporarily open cell walls – from inexpensive components, including a piezoelectric crystal taken from a butane lighter.
For the first time, researchers at Michigan Medicine have demonstrated that macropinocytosis, a cellular process known to be involved in cancer and other diseases, also plays an important role in the growth of at least one type of normal mammalian cell.
The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes underlying all of life.
An international team of researchers led by UCLA’s Paul Boutros, have created a new way to accurately estimate how fast an individual cancer is evolving using open-source software.
In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) outline distinct and critical changes to stem cells in males during adolescence.
Below are summaries of recent Fred Hutch research findings with links for additional background and media contacts.
Using a genomics strain-tracking bioinformatics tool, analyzed two metagenomic sequencing databases from pairs of twins — one for children who were still living together and the other from adult twins, ages 36 to 80, who then lived apart for periods from one to 59 years.
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