Feature Channels: Cell Biology

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Researchers at Washington University School of Medicine in St. Louis have mapped nine functional networks in the deep-brain structures of 10 healthy people, an accomplishment that could lead to improvements in deep-brain stimulation therapy for severe cases of Parkinson’s disease and other neurological conditions.

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Results from a study conducted by St. Jude Children’s Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

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Researchers develop protocells that better mimic living cells to help understand cell movement

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Within weeks, CAR T cells targeting ovarian cancer cleared tumors in 70% of treated mice, shows study in Nature Biomedical Engineering. (Note: Images available for media use).

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Results of studies on a novel agent to treat multiple myeloma and a combination therapy aimed at slowing the progression of a precursor myeloma condition are among reports being presented by Dana-Farber Cancer Institute investigators at the ASH Annual Meeting.

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Pioneering research gives fresh insight into one of the pivotal building blocks of life

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In mere milliseconds trillions of chemical reactions ignite signals that travel across the billions of neurons in our brain. As we go through our daily lives and absorb new knowledge these neurons begin to modify themselves and change their signaling properties.

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For older patients with acute myeloid leukemia (AML), the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute and other research centers will report today at the ASH Annual Meeting.

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A new technique reported in Science offers more detail, at the single cell level, on how large, pooled samples of various cells react to drugs or other agents. The data might reveal mode of action or the effect of genetic differences in varying responses.

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Researchers from St. Jude Children’s Research Hospital will present their work at the 61st annual meeting of the American Society of Hematology.

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Researchers have found a way to speed engineered-tissue creation using a novel bioprinter built for $2,000, they report in the journal Micromachines. Building blocks for the tissue are pre-grown spheroids of human induced-pluripotent stem cells that contain 200,000 cells per spheroid.

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New study reveals hierarchy of behaviors in a single-cell organism The organism, S. roeselii, appears to “change its mind” and modify its response to repeated exposure to irritating particles Findings suggest certain single-cell organisms may have the capacity for relatively complex "decision-making"

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A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.

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Researchers have discovered key mechanisms and structural details of a fundamental biological process—how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new findings in chromosomal architecture and function may offer important insights into human health and disease.

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Check out this day-by-day rundown of events and sessions of interest to media at the 2019 ASCB|EMBO Meeting taking place Dec. 7-11 at the Walter E. Washington Convention Center in Washington, DC.

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The December 2019 issue of Toxicological Sciences features research on the leading edge of toxicology, including in the areas of carcinogenesis, developmental and reproductive toxicology, and more.

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Mass. Eye and Ear scientists report the identification of a new pathway linked to cell division in the ear. With this pathway, they were able to reprogram the inner ear’s cells to proliferate and regenerate hair cell-like cells in adult mouse models.