Feature Channels: Drug Resistance

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Newswise: Cleveland Clinic Researchers Shed New Light on Importance of Ecological Cellular Interactions in Targeted Therapy Resistance in Lung Cancer
30-Jun-2022 10:40 AM EDT
Cleveland Clinic Researchers Shed New Light on Importance of Ecological Cellular Interactions in Targeted Therapy Resistance in Lung Cancer
Cleveland Clinic

New Cleveland Clinic research has uncovered key information about cellular interaction between tumor cells and normal tissue, providing better understanding of how therapeutic resistance develops. Findings published in Science Advances.

Newswise: Highly Antibiotic-Resistant Strain of MRSA That Arose in Pigs Can Jump to Humans
Released: 28-Jun-2022 1:05 PM EDT
Highly Antibiotic-Resistant Strain of MRSA That Arose in Pigs Can Jump to Humans
University of Cambridge

A new study has found that a highly antibiotic-resistant strain of the superbug MRSA – methicillin resistant Staphylococcus aureus – has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming.

   
Newswise: Caught in the act: Researchers find deadly fungus can multiply by having sex, which could produce more drug-resistant, virulent strains
Released: 27-Jun-2022 9:00 AM EDT
Caught in the act: Researchers find deadly fungus can multiply by having sex, which could produce more drug-resistant, virulent strains
McMaster University

Researchers at McMaster University have unlocked an evolutionary mystery of a deadly pathogen responsible for fueling the superbug crisis: it can reproduce by having sex.

Newswise: National Researcher of the Year 2022 Decodes Drug Resistance in Animals – A Step towards Sustainable Solutions
Released: 24-Jun-2022 8:15 AM EDT
National Researcher of the Year 2022 Decodes Drug Resistance in Animals – A Step towards Sustainable Solutions
Chulalongkorn University

Chula Veterinary Lecturer and “National Outstanding Researcher 2022” has revealed the genetic code that causes drug resistance in animals that affects human health, animals, and the environment, and suggests comprehensive solutions under the concept “One Health”.

Newswise: Computer Simulations of Proteins Help Unravel Why Chemotherapy Resistance Occurs
Released: 21-Jun-2022 8:05 AM EDT
Computer Simulations of Proteins Help Unravel Why Chemotherapy Resistance Occurs
Stony Brook University

Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer. A team of scientists including Markus Seeliger, PhD, of the Renaissance School of Medicine at Stony Brook University, believe they have found a new process through which drug resistance happens.

Released: 15-Jun-2022 2:30 PM EDT
Moffitt Researchers Contribute to Discovery of Mechanism Leading to Drug Resistance in Prostate Cancer
Moffitt Cancer Center

In a new article published in Science Translational Medicine, Moffitt Cancer Center researchers reveal a mechanism by which prostate cancer cells become resistant through molecular modification of the androgen receptor protein and identify a potential treatment approach that could overcome this resistance.

Released: 7-Jun-2022 5:05 PM EDT
Scientists Show How Fast-Growing Bacteria Can Resist Antibiotics
eLife

Scientists have demonstrated how some fast-growing bacteria can retreatment with antibiotics, according to a study published today in eLife.

Released: 7-Jun-2022 3:05 PM EDT
Common Drug-Resistant Superbug Develops Fast Resistance to ‘Last Resort’ Antibiotic
University of Oxford

A study published today in Cell Reports reveals how populations of a bacterium called Pseudomonas respond to being treated with Colistin, a 'last resort' antibiotic for patients who have developed multi-drug resistant infections.

Released: 31-May-2022 3:05 PM EDT
Most Doctors Still Believe in Prescribing Unnecessary Antibiotics to Treat Asymptomatic Infections, UM School of Medicine Study Suggests
University of Maryland School of Medicine

An estimated 70 percent of primary care physicians reported in a survey that they would still prescribe antibiotics to treat asymptomatic infections based solely on a positive urine specimen.

Newswise: Mystery Mechanism in Small Peptide Shows Big Promise for Fighting Antibiotic-Resistant Bacteria
Released: 26-May-2022 4:00 PM EDT
Mystery Mechanism in Small Peptide Shows Big Promise for Fighting Antibiotic-Resistant Bacteria
Oak Ridge National Laboratory

Using neutrons, researchers at Oak Ridge National Laboratory pieced together the molecular mechanics behind a peptide’s ability to deal significant damage to bacterial cells. Their findings could inform new therapeutic strategies for treating bacterial infections where antibiotics have fallen short.

Newswise: Diabetes Drug Improves Antibacterial Treatment Speed and Effectiveness, Researchers Report
Released: 26-May-2022 2:05 PM EDT
Diabetes Drug Improves Antibacterial Treatment Speed and Effectiveness, Researchers Report
Tsinghua University Press

Old dogs may not learn new tricks, but old drugs can, according to a research team based in China.

Released: 26-May-2022 11:55 AM EDT
Gut bacteria can make blood pressure medication less effective
University of Toledo

A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs.

24-May-2022 5:05 PM EDT
Inappropriate Antibiotics for Nonhospitalized Kids Cost US at Least $74 Million
Washington University in St. Louis

Children who were prescribed antibiotics inappropriately were more likely to develop complications such as diarrhea and skin rashes than children who were treated according to medical guidelines, according to a new study from Washington University School of Medicine in St. Louis and The Pew Charitable Trusts. This misuse of antibiotics resulted in at least $74 million in excess health-care costs in the U.S. in 2017.

Newswise: Hospitals Can Reduce Antibiotic Overuse by Avoiding Unnecessary Blood Draws in Critically Ill Children, Study Shows
Released: 2-May-2022 11:05 AM EDT
Hospitals Can Reduce Antibiotic Overuse by Avoiding Unnecessary Blood Draws in Critically Ill Children, Study Shows
Johns Hopkins Medicine

A Johns Hopkins Children’s Center-led national quality improvement collaborative highlights a “less is more” method that may prevent antibiotic overprescribing

26-Apr-2022 12:35 PM EDT
New Model for Antibacterial Mechanism: Toxic Misinformation
Brookhaven National Laboratory

Biologists have discovered an aberrant protein that’s deadly to bacteria. The discovery could help scientists unravel the lethal mechanism of certain antibiotics—and potentially point the way to future antibacterial drugs.

Newswise: Study Reveals Genetic Diversity of a Particularly Problematic Pathogen
Released: 27-Apr-2022 3:55 PM EDT
Study Reveals Genetic Diversity of a Particularly Problematic Pathogen
UC San Diego Health

Researchers at UC San Diego have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen, particularly in health care settings.

Released: 25-Apr-2022 2:05 PM EDT
Offspring weakens, when parents are given antibiotics
University of Southern Denmark

Antibiotics have once proclaimed the salvation of the world. Today, researchers fear that antibiotics could become a threat to public health and the natural environment.

   
Released: 25-Apr-2022 11:05 AM EDT
US study suggests COVID-19 pandemic may be accelerating antimicrobial resistance
European Society of Clinical Microbiology and Infectious Diseases

Among those hospitalised during the pandemic, both COVID-19 patients and those tested for SARS-COV-2 but negative, had higher rates of antibiotic-resistant bacterial infections compared to patients hospitalised before the pandemic, according to a study evaluating the pandemic’s impact on antimicrobial resistance (AMR) in 271 hospitals across the USA, to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April).

Released: 21-Apr-2022 3:05 PM EDT
Scientists use machine learning to identify antibiotic resistant bacteria that can spread between animals, humans and the environment
University of Nottingham

Experts from the University of Nottingham have developed a ground-breaking software, which combines DNA sequencing and machine learning to help them find where, and to what extent, antibiotic resistant bacteria is being transmitted between humans, animals and the environment.



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