Feature Channels: Infectious Diseases

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Dr Howard H.Z. Thom of the University of Bristol says it is grossly misleading to attribute the 1 million excess deaths solely to response.

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A COVID-19 vaccine that could provide protection against both existing and future strains of the COVID-19 virus, and other coronaviruses, and cost about $1 a dose has shown promising results in early animal testing.

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In support of World TB Day, March 24, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, joins the World Health Organization campaign urging governments to act on the commitments made to end TB.

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Researchers reporting in ACS’ Nano Letters have transformed copper nanowires into metal foams that could be used in facemasks and air filtration systems. The foams filter efficiently, decontaminate easily for reuse and are recyclable.

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A luta global contra a tuberculose está ganhando algumas ferramentas poderosas. A medicina de precisão — já usada para personalizar o diagnóstico e o tratamento de doenças não transmissíveis, como o câncer — e as tecnologias de saúde, como a telemedicina, têm potencial para avançar na prevenção e no tratamento da tuberculose, afirma Zelalem Temesgen, M.D.

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全球抗击肺结核的努力获得了医疗技术的强大助力。精准医学已经用于非传染性疾病（例如癌症）的诊断和治疗，它和远程医学等医疗技术有可能促进结核病的预防和治疗，妙佑医疗国际 (Mayo Clinic) 肺结核中心的传染病专家和医学主任 Zelalem Temesgen 医学博士 说。

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People who received a flu shot last flu season were significantly less likely to test positive for a COVID-19 infection when the pandemic hit, according to a new study. And those who did test positive for COVID-19 had fewer complications if they received their flu shot.

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The COVID-19 pandemic has had devastating effects in U.S. nursing homes and long-term care facilities, resulting in an estimated 1.2 million infections and 147,000 deaths as of early 2021. Yet even as mortality rates in the general population have decreased over time, little evidence has been uncovered to determine whether nursing home residences have experienced similar reductions.

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Blood from critically ill COVID-19 patients contains antibodies that can contribute to clotting. These antibodies form immune complexes that activate platelets, the cells that lead to blood clot formation. Some blood-thinner medications can block these immune complexes and potentially reduce clots.

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Wistar is pleased to announce the appointment of Richard M. Horowitz as chair of its Board of Trustees.

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Researchers at the Oak Ridge National Laboratory used neutron scattering to investigate the interactions between telaprevir, a drug used to treat hepatitis C viral infection, and the SARS-CoV-2 main protease, the enzyme responsible for enabling the virus to reproduce. Unforeseen changes in the electric charges were discovered in the drug binding site of the protease enzyme that were not predicted by prevailing computer simulations. The research provides key insights for advancing drug design and drug repurposing efforts to treat COVID-19.

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Fluid mechanics-based transport modeling in the human respiratory tract and research data were used to determine which droplet sizes are most like to reach the dominant infection site and the number of virus particles needed to trigger infection.

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DALLAS – March 23, 2021 – Vaccinating health care workers resulted in an immediate and notable reduction of positive COVID-19 cases among employees, reducing the number of required isolations and quarantines by more than 90 percent, according to data at UT Southwestern Medical Center published in the New England Journal of Medicine.

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IU study finds COVID-19 differs from other coronaviruses which may be contributing to difficulty in controlling disease spread and burden.

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Investigators from UC San Diego and UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus. Risk of infection is minuscule, but exists.

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接受第二剂信使RNA或mRNA COVID-19疫苗10天后，与未接种COVID-19疫苗的患者相比，无症状COVID-19感染者检测为阳性和在不知不觉中传播COVID-19的可能性大幅降低。Pfizer-BioNTech和Moderna信使RNA COVID-19疫苗已在美国获得紧急使用授权。

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Dez dias após receber uma segunda dose de uma vacina para COVID-19 de RNA mensageiro, ou mRNA, pacientes sem sintomas de COVID-19 têm muito menos probabilidade de apresentar teste positivo e espalhar COVID-19 inadvertidamente, em comparação com pacientes que não foram vacinados para COVID-19.

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Most delays ranged between 10 and 45 days, with a median of 24 days, after a visit to a doctor, which exceeds current World Health Organization recommendations of diagnosing and treating TB within two to three weeks of symptom onset Delays were linked to greater risk for disease complications, transmission of infection to household members Older individuals and those with compromised immunity were at greater risk for delayed diagnoses Use of diagnostic molecular testing, use of chest imaging and being seen by a specialist were all linked to more prompt identification of TB infection, suggesting delays may be preventable Findings underscore the need to increase awareness of TB among frontline clinicians who may not suspect TB due to rarity of infection in this country

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One year has passed since stay-at-home orders went into effect across the U.S. and the COVID-19 pandemic changed our lives in profound ways. During this dark year, we've witnessed overwhelming loss of life and livelihood, and separation from those we love. But we have also seen courageous patients and heroic healthcare workers battling the disease, as swift breakthroughs have brought us vaccines and hope.