DHS S&T partnered with two universities to develop training programs for individuals who will develop the next generation of TAD identification, prevention, and mitigation capabilities.
In the second of two high-profile articles published in recent weeks, SLU scientist Mee-Ngan F. Yap, Ph.D, continues to uncover the secrets of how ribosomes hibernate under stressful conditions.
Anna Giuliano, Ph.D., director of Moffitt Cancer Center’s Center for Infection Research in Cancer, delivered the opening keynote address at the 2017 European Research Organization on Genital Infection and Neoplasia (EUROGIN) International Multidisciplinary Congress. The focus of this year’s conference is human papillomavirus (HPV) and its associated cancers.
UCLA researchers have developed an improved technique for creating simplified human brain tissue from stem cells. Because these so-called “mini brain organoids” mimic human brains in how they grow and develop, they’re vital to studying complex neurological diseases.
A Texas researcher has received a two-year, $420,000 grant from the National Institute of Allergy and Infectious Disease (NIAID) to study the mosquito-borne virus Zika. With the NIAID grant, Wu and his colleagues at Texas Tech University Health Sciences Center El Paso (TTUHSC El Paso) will try to determine which human genes enable the virus to attack and kill human cells. To do this, Wu will conduct a genome-wide knockout screening — a process that specifically knocks out, or deactivates, each gene in the human genome —to identify the genes involved by process of elimination.
Surgeons at Penn Medicine are using a fluorescent dye that makes cancerous cells glow in hopes of identifying suspicious lymph nodes during head and neck cancer procedures. Led by Jason G. Newman, MD, FACS, an associate professor of Otorhinolaryngology in the Perelman School of Medicine at the University of Pennsylvania, the study is the first in the world to look at the effectiveness of intraoperative molecular imaging (IMI) of lymph nodes in patients with head and neck cancer.
Cells lining blood vessels in the lungs that are exposed to bacterial toxins don’t die easy, according to a new study led by researchers at the University of Illinois at Chicago College of Medicine.
UF scientists synthesized and examined data from prior studies that had looked at how many pathogen-carrying mosquito species made their homes in forested lands vs. non-forested lands in 12 countries worldwide, including the United States.
Certain proteins in the influenza virus remain constant year after year. Researchers at Cornell University are taking one of those conserved proteins, Matrix-2 (M2), and packaging it in a nanoscale, controlled-release “capsule” in an attempt to create a quick-acting, long-lasting, multi-strain vaccine against pandemic influenza A.
U.S. Olympic and Paralympic athletes and staff who traveled to Rio de Janeiro, Brazil, for the 2016 Summer Games did not become infected with Zika virus but did test positive for other tropical, mosquito-borne viral infections, including West Nile Virus, Dengue Fever and Chikungunya. Results from the University of Utah Health-led study will be reported at IDWeek, a national infectious disease conference being held in San Diego.
A new test allows accurate, rapid testing for Salmonella, a bacteria that is one of the leading causes of food-borne illness across all regions of the world.
Scientists have developed an agent to “wake up” HIV lying dormant in cells, which causes it to begin replicating so that either the immune system or the virus itself would kill the cell harboring HIV. They call the technique “kick and kill.”
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans, according to new research from the Perelman School of Medicine at the University of Pennsylvania, conducted in partnership with The Wistar Institute, Inovio Pharmaceuticals, and GeneOne Life Science, Inc. In results published today in the New England Journal of Medicine, the phase 1 clinical trial showed for the first time that humans who received up to three doses of the vaccine candidate produced an immune response against Zika with minimal adverse effects, opening the door to further clinical trials for this important vaccine candidate.
Scientists have determined that fungus may play a key role in chronic intestinal inflammation disorders. They found that patients with Crohn’s disease tend to have much higher levels of the fungus Candida tropicalis compared to their healthy family members. A new review published in Digestive and Liver Disease looks at these findings and provides insights into potential new therapeutic approaches using antifungals and probiotics in the treatment of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD).
Light-activated nanoparticles, also known as quantum dots, can provide a crucial boost in effectiveness for antibiotic treatments used to combat drug-resistant superbugs such as E. coli and Salmonella, new University of Colorado Boulder research shows.
Preliminary findings presented at this year’s American Society for Radiation Oncology Annual Meeting suggest a genetic test for HPV16 in the blood could be useful to help assess risk for patients, and could help identify patients suitable for lower treatment doses.
As the large, invasive Burmese python eats its way through south Florida’s mammals, the mosquitoes in the area have fewer types of animals to bite. Now, more mosquitoes are drawing blood from a rat that carries a virus dangerous to humans.
Researchers from Boise State and University of Idaho recently were awarded a three year, $418,000 grant from the National Institutes of Health to develop and test new anti-parasitic drugs to fight Giardia infections.
Research from Cornell University mycologist Kathie Hodge and doctoral candidate Megan Biango-Daniels reveals varying levels of mold contamination in commercial sea salts. Among those molds were important food spoilage molds like Aspergillus and Penicillium, and even some notorious producers of mycotoxins.
The National Institute on Drug Abuse has awarded $5 million to researchers at UCLA to develop a resource and data center for millions of pieces of research, lab samples, statistics and other data aimed at boosting research into the effects of substance abuse on HIV/AIDS.
If you diabetes and haven’t been vaccinated, it’s time to reconsider. Flu can be more serious than you realize, and health officials say there are early signs that this flu season will be a bad one.
Researchers at Thomas Jefferson University studying combinations of drugs against HIV have discovered why certain drugs sometimes act synergistically but sometimes do not.
Using an influenza infection model in mice, researchers find a particular population of immune cells develops during the later stages of the immune response to the influenza. These cells, called T follicular regulatory cells, prevent the generation of self-reactive antibody responses.
A research team at the University of Pennsylvania will receive $8.6 million in funding to study the effectiveness of home-based phototherapy treatments for psoriasis compared to treatments that require a visit to a doctor’s office three times a week.
Southern Illinois University School of Medicine and the University of Chicago Medicine will use a $1.13 million federal grant to study the opioid epidemic affecting the state’s 16 southernmost counties.
A study that teases apart the biological mechanisms by which human papillomaviruses (HPV) cause cancer has found what researchers at Georgetown University Medical Center say is a new strategy that might provide targeted treatment for these cancers.
A new study by researchers has identified an innovative strategy for treating influenza, and perhaps other infectious diseases as well. Scientists showed that a small protein called retrocyclin-101 (RC-101) could potentially improve the symptoms and mortality associated with the flu and possibly other types of infectious illness as well.
A new study shows white children in America are more likely to see a doctor for treatment of eczema than black children, despite the fact that the disease is likely more severe among minorities.
Scientists are closer to discovering what makes some individuals better able to clear viral infections than others can, thanks to a new study by researchers at Rutgers Robert Wood Johnson Medical School's Child Health Institute of New Jersey and the University of Chicago.
The health effects of where people live, work, and interact are well documented, as are the value of neighborhood-level structural interventions designed to improve health. But place-based characteristics that contribute to disparities in HIV transmission and disease burden are poorly understood, possibly resulting in less-effective HIV risk reduction interventions and programming.
Two new papers by researchers at the Johns Hopkins Bloomberg School of Public Health’s Malaria Research Institute report successes for highly promising strategies against malaria, a disease that still kills more than 400,000 people each year, mostly children age five and under in sub-Saharan Africa.
The University of Illinois at Chicago College of Nursing has received a four-year federal grant to assist HIV-positive prisoners in Indonesia — a southeast Asian country where the number of new infections is increasing rapidly.
An international team of researchers has developed a simple way for healthcare providers to quickly identify and prioritize patients at the greatest risk of death.
Each year, the flu season is a bit of a guessing game. While much is left to chance, some things can be done to plan for and prevent influenza, which is responsible for thousands of deaths each year nationwide.
A collaboration among research institutions, private industry, and the US Government will develop a tetravalent vaccine to protect against four viruses that can be fatal
The University of Chicago’s Center for Interdisciplinary Inquiry and Innovation (Ci3) in Sexual and Reproductive Health was awarded a grant to increase access to PrEP in drugstore pharmacies in communities with high rates of STI and HIV infection.
A pilot program that uses big data to predict which lung cancer patients will require a trip to an emergency department (ED) successfully anticipated a third of all ED visits over a two week trial period, and was further able to identify which patients were at high risk and low risk of requiring such care. The predictive model was designed by researchers at the Perelman School of Medicine at the University of Pennsylvania with the eventual goal of developing a tool for early intervention that will help patients avoid ED visits.
If you are eating leftover pork chops that have not been cooked well-done, you’re putting yourself at risk for Salmonella and Listeria exposure. While many individuals prefer to consume their pork medium, a new study published in Risk Analysis: An International Journal revealed that cooking pork chops to an acceptable temperature does not completely eliminate pathogens, providing these cells with the opportunity to multiply during storage and harm consumers.
For children with Staphylococcus aureus (staph) infections, prescribing antibiotics — in addition to lancing and draining — may reduce the risk of recurrent infections, according to Washington University School of Medicine.
The National Institutes of Health has awarded a $2.5 million grant to researchers at The University of Texas Health Science Center at Houston (UTHealth) to develop a standard protocol for anal cancer screenings for men who have sex with men.
Mayo Clinic researchers have found that a 50 percent reduction in the intensity and dose of radiation therapy for patients with HPV-related throat cancer reduced side effects with no loss in survival and no decrease in cure rates.
For certain patients with oropharyngeal cancer caused by the human papilloma virus (HPV), an aggressive reduction of radiation therapy after surgery may provide excellent cancer control while simultaneously reducing post-treatment side effects, improving quality of life and lowering treatment costs, according to research presented today at the 59th Annual Meeting of the American Society for Radiation Oncology (ASTRO).
In a new phase III trial report from the National Clinical Trial Network group, NRG Oncology, recurrence-free and overall survival rates for women with stage I-II high-risk endometrial cancer were not superior following vaginal cuff brachytherapy plus chemotherapy when compared with pelvic radiation therapy.
The same countries hard hit by Zika virus – which can cause brain damage in babies infected before birth – are also home to dengue virus. Washington University School of Medicine in St. Louis researchers report that they have found an antibody that protects against both viruses. These findings, in mice, could be a step towards an antibody-based preventative drug to protect fetuses from brain damage, while also protecting their mothers from both Zika and dengue disease.
More than 100 physicians from UC San Diego Health were named “Top Docs” in the annual San Diego Magazine “Physicians of Exceptional Excellence” annual survey. These physicians represent 45 diverse specialties, from infectious disease, surgery and oncology to obstetrics, cardiology and emergency medicine.
The National Cancer Institute (NCI) has selected UT Southwestern Medical Center cancer researcher Dr. Ralph DeBerardinis to receive its prestigious Outstanding Investigator Award. The award includes annual funding of $600,000 for seven years to support Dr. DeBerardinis’ continuing research into changes in cellular metabolism that occur in cancer.