Feature Channels: Genetics

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Released: 20-Apr-2020 3:25 PM EDT
Neolithic genomes from modern-day Switzerland indicate parallel ancient societies
Max Planck Institute for the Science of Human History

Genetic research throughout Europe shows evidence of drastic population changes near the end of the Neolithic period, as shown by the arrival of ancestry related to pastoralists from the Pontic-Caspian steppe.

Released: 20-Apr-2020 3:10 PM EDT
CSIRO unlocks new way to understand evolving strains of SARS-CoV-2
University of York

Researchers from CSIRO, Australia's national science agency, have unveiled a new approach to analysing the genetic codes - or the blueprint - of the SARS-CoV-2 virus that causes COVID-19.

20-Apr-2020 12:05 PM EDT
NEI researchers link age-related DNA modifications to susceptibility to eye disease
NIH, National Eye Institute (NEI)

National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression. The findings, published online April 21 in Cell Reports, suggest that the epigenome could be targeted as a therapeutic strategy to prevent leading causes of vision loss, such as age-related macular degeneration (AMD).

Released: 20-Apr-2020 12:05 PM EDT
Finding Leukemia’s Weakness Using Genome-Wide CRISPR Technology
UC San Diego Health

Researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia.

Released: 20-Apr-2020 11:30 AM EDT
University of Utah Invests $1.3 million in COVID-19 Research, from Investigating Domestic Violence to Drug Development
University of Utah Health

The University of Utah has awarded $1.3 million in grants to 56 projects that will examine a host of issues arising out of the pandemic. These multidisciplinary projects will not only address ways to prevent and treat the disease, but will also explore how to design better personal protective equipment as well as dampen the long-term effects of physical isolation on domestic violence and mental health.

   
17-Apr-2020 4:50 PM EDT
Picking Up Threads of Cotton Genomics
Lawrence Berkeley National Laboratory

In Nature Genetics, a multi-institutional team including DOE Joint Genome Institute researchers sequenced and assembled the genomes of the five major cotton lineages to provide breeders with genetic level insights on crop improvements. The genomes are available on JGI’s plant data portal Phytozome.

Released: 17-Apr-2020 2:10 PM EDT
The origin of feces: coproID reliably predicts sources of ancient poop
Max Planck Institute for the Science of Human History

The archaeological record is littered with feces, a potential goldmine for insights into ancient health and diet, parasite evolution, and the ecology and evolution of the microbiome.

16-Apr-2020 2:50 PM EDT
Researchers predict menopause will start later and possibly disappear as parents have kids later
McMaster University

As mothers continue having children later in life, it is inevitable that menopause will be delayed, and possibly cease to exist altogether, say researchers at McMaster University.

Released: 16-Apr-2020 12:45 PM EDT
Designing peptide inhibitors for possible COVID-19 treatments
Newswise Review

Scientists across the globe are rushing to find inhibitors of SARS-CoV-2, the new coronavirus behind the COVID-19 pandemic. Some are using computer simulations to identify promising compounds before conducting actual experiments in the lab.

Released: 16-Apr-2020 8:35 AM EDT
أظهرت الدراسة أن المتغيرات الجينية قد تزيد من قابلية تراكم بروتين داء الزهايمر تاو
Mayo Clinic

يُعدُّ بروتين تاو السام سمة بيولوجية أساسية في أدمغة الأشخاص المصابين بداء الزهايمر. ومع ذلك، فإن العوامل التي تجعل الناس عُرضة أو مقاومة لتراكم بروتين تاو ليست مفهومة تمامًا. أظهرت دراسة أولية أجرتها مايو كلينك (Mayo Clinic) أن متغيرات الحمض النووي الوراثيقد يأتي معها نمو ترسُّبات بروتين تاو لدى البالغين الأكبر سنًّا. سيُقدم البحث في الاجتماع السنوي رقم 72 للأكاديمية الأمريكية لطب الأعصاب في تورونتو في الفترة من 25 أبريل/نيسان إلى 1 مايو/أيار

Released: 16-Apr-2020 8:35 AM EDT
Estudo mostra que as variantes genéticas podem aumentar a suscetibilidade para acumular a proteína tau do Alzheimer
Mayo Clinic

A proteína tóxica tau é uma característica essencial biológica no cérebro de pessoas com a doença de Alzheimer. No entanto, os fatores que tornam as pessoas suscetíveis ou resistentes ao acúmulo de tau não são bem compreendidos.

Released: 16-Apr-2020 8:30 AM EDT
研究显示,基因变异可能会增加阿尔茨海默病蛋白tau累积的易感性
Mayo Clinic

有毒蛋白tau是阿尔茨海默病患者大脑中的一个关键生物学特征。然而,使人对tau累积产生易感性或抵抗性的因素目前尚未明确。Mayo Clinic的一项初步研究表明,遗传的DNA变异可能与老年人出现的tau累积有关。这项研究将在4月25日至5月1日在多伦多举行的美国神经病学学会第72届年会上公开发表。

Released: 13-Apr-2020 11:05 AM EDT
Foxglove plants produce heart medicine. Can science do it better?
University at Buffalo

Biologist Zhen Wang’s team recently published a pair of papers detailing characteristics of cardiac glycosides in two foxglove species. “This kind of study is important because we first have to know the accurate structure of natural compounds before we can explore their medicinal effects,” she says.

Released: 13-Apr-2020 9:00 AM EDT
A Type of Small RNA Found To Depend on Personal Attributes
Thomas Jefferson University

Jefferson researchers discover that the abundances of yet another class of short RNAs differ by a person’s gender and population of origin.

Released: 10-Apr-2020 8:20 AM EDT
UTSW researchers use snake venom to solve structure of muscle protein
UT Southwestern Medical Center

Researchers at UT Southwestern Medical center have uncovered the detailed shape of a key protein involved in muscle contraction.

Released: 9-Apr-2020 2:20 PM EDT
Researchers Reveal Important Genetic Mechanism Behind Inflammatory Bowel Disease
Children's Hospital of Philadelphia

Researchers at Children’s Hospital of Philadelphia (CHOP) have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease (IBD). The genetic pathway associated with this variation is involved in other immune disorders, suggesting the mechanism they identified could serve as an important therapeutic target.

8-Apr-2020 10:35 AM EDT
Mount Sinai Researchers Discover a Novel Role for Dopamine That Impacts Gene Expression Related to Cocaine Abuse
Mount Sinai Health System

Scientists at the Icahn School of Medicine at Mount Sinai have discovered a new role for the brain chemical dopamine that is independent of classic neurotransmission. The new role appears to be critical to changes in gene expression related to chronic exposure to, or abuse of, cocaine, according to a study published Friday, April 10, in the journal Science.

9-Apr-2020 9:40 AM EDT
NYU Langone Scientists Tracking Genetic Evolution of Coronavirus in New York City
NYU Langone Health

As of April 9, NYU Grossman School of Medicine researchers had determined the genetic code for COVID-19 virus taken from 91 New York City patients during the current pandemic, the researchers say.

Released: 9-Apr-2020 9:00 AM EDT
Mount Sinai Study Finds First Cases of COVID-19 in New York City are Primarily from European and US Sources
Mount Sinai Health System

First definitive molecular epidemiology study of SARS-CoV-2 in New York City to describe the route by which the virus arrived

Released: 9-Apr-2020 8:30 AM EDT
Researchers Uncover Importance of Aligning Biological Clock with Day-Night Cycles
University of California San Diego

Scientists studying bacteria have identified the roots of a behavior that is regulated by the circadian clock. The research provides a striking example of the importance of keeping the internal biological clock aligned with the external environment so that processes occur at the right time of day.



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