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Medicine

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Differentiation, T Cell, gene programs, Embryonic Stem Cells, tran, Epigenetic, Epigenomic, genome topology, Metabolism, Glutamine, alpha-ketoglutarate, ccctc-binding factor, Ctcf

How a Nutrient, Glutamine, Can Control Gene Programs in Cells

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An intracellular metabolite of glutamine regulates cellular differentiation programs by changing the DNA-binding patterns of a transcription factor and by altering genome interactions. Genome context near the binding sites affects whether the binding turns on or turns off gene programs.

Medicine

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Immune System, Innate Immune System, Viral Infections, Viruses, Infection

Organs Fight Infections That Enter Through the Skin

New information about how and where the innate immune system fights off viral infections that enter through the skin could lead to better treatments for viruses like Zika, dengue and measles, according to Penn State College of Medicine researchers.

Medicine

Science

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Virus, Molecular Imaging, Virology, XFEL, BioXFEL, x-ray free-electron laser, Infection, Physics

Now Showing: Researchers Create First 3D Movie of Virus in Action

Imaging the movement of a virus demonstrates that single-particle X- ray scattering has the potential to shed new light on key molecular processes, like viral infection, when paired with powerful new algorithms.

Medicine

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FDA Approves Emergency Use for Multiplex Zika Test

US FDA grants emergency use of Columbia University's 'multiplex' test for Zika, dengue, chikungunya, and West Nile viruses.

Medicine

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Virus, Viruses, Ebola, Marburg, hantaviruses, Pathogens, Microbiology, Antibodies, Filoviruses, Disease, Vaccines

Einstein Researchers Awarded Three NIH Grants Totaling $12Million to Fight Virulent Viruses

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The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses—Ebola, Marburg and hantavirus. Research collaborations between Kartik Chandran, Ph.D., professor of microbiology & immunology and the Harold and Muriel Block Faculty Scholar in Virology, and Jonathan Lai, Ph.D., associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments.

Medicine

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zika virus, Nanotechnology, gold nanorods, Emerging Infectious Diseases

Test Uses Nanotechnology to Quickly Diagnose Zika Virus

Currently, testing for Zika requires that a blood sample be refrigerated and shipped to a medical center or laboratory, delaying diagnosis and possible treatment. Now, Washington University in St. Louis researchers have developed a test that quickly can detect the presence of Zika virus in blood. Although the new proof-of-concept technology has yet to be produced for use in medical situations, test results can be determined in minutes, and the materials do not require refrigeration.

Medicine

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HPV, Vaccine, Cancer, UCLA Jonsson Cancer Center, Sex, Human Papilloma Virus, UCLA, Ucla Medical Center, David Geffen School of Medicine at UCLA

Protecting Kids Against HPV Before Cancer Risk Increases

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It is that time of year for kids returning to school to get vaccinated before the school year starts. But the controversy over the HPV vaccine continues to rage as it has since its introduction in the U.S. in 2014.

Medicine

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HIV, AIDS, Hiv Aids, Paris Declaration, Center for AIDS Research

Birmingham Among 13 U.S. Cities Committed to End the Spread of AIDS by 2030

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• Birmingham committed to the “90:90:90” principle, whereby 90 percent of people living with HIV will know their HIV status, 90 percent of those who know their status will be engaged with clinical care and on anti-HIV therapy, and 90 percent of those on treatment will achieve full viral suppression • Paris Declaration confirms 13th city to commit to being a Fast-Track City in the effort to end the spread of HIV/AIDS • HIV/AIDS research powerhouse, UAB stands behind commitment of city to end the spread of the disease

Medicine

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Northern Arizona University, Center for Ecosystem Science and Society, Bruce Hungate, Ben Koch, human microbiome, colonizing opportunistic pathogens, Cops, Pathogens, Infectious Disease, Fungi, Protozoa, Virus, Bacteria

Scientists Urge Further Study of “the Beasts in All of us”—Colonizing Opportunistic Pathogens (COPs)

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A new paper published in PLOS Pathogens by a team of researchers comprised of Bruce Hungate and Ben Koch from Northern Arizona University; Lance Price from George Washington University and the Translational Genomics Research Institute; and Gregg Davis and Cindy Liu from George Washington University outlines the critical need for further research into the nature of colonizing opportunistic pathogens, or COPs.

Medicine

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Review: Cholera Vaccines Effective for Adults, Much Less So for Children

A new review of the research literature led by researchers at the Johns Hopkins Bloomberg School of Public Health shows that cholera vaccines provide substantial protection for adults but provide significantly less protection for children under age 5, a population particularly at risk for dying from this diarrheal disease.







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