A team led by engineers at Tufts University has opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution. The researchers were able to use the method to identify specific metabolic signatures that could arise in diabetes, cancer, cardiovascular and neurodegenerative diseases.
Illnesses and injuries associated with working in Illinois mines are substantially underreported to the federal agency tasked with tracking these events, according to a new study published in the American Journal of Industrial Medicine.The U.S. Department of Labor’s Mine Safety and Health Administration requires reporting of injuries and illness sustained while working in mines in the U.
Researchers found that the fruit fly blood brain barrier has a molecular clock that makes it more penetrable during certain hours of the day. Giving mutant flies a drug for treating seizures at night was more effective.
Argonne researchers have found that in the next 100 years, already existing reforestation in the country could help topsoil absorb an additional 2 billion tons of carbon. Their work is detailed in a recent study in the Proceedings of the National Academy of Sciences.
Un nuevo estudio de Mayo Clinic plantea que hasta el 97 por ciento de los pacientes no se incomodan cuando los proveedores de atención médica les preguntan acerca de su orientación sexual e identidad de género.
Children with mitochondrial diseases who suffered acute metabolic strokes benefited from rapid intravenous treatment with the amino acid arginine, experiencing no side effects from the treatment. In half of the stroke episodes, patients showed clinical improvements in symptoms such as seizures and partial paralysis.
Use of tests that assess genomic variants in circulating tumor DNA (ctDNA) is on the rise. A new joint review from the American Society of Clinical Oncology (ASCO) and the College of American Pathologists (CAP) provides an assessment of evidence on ctDNA tests in oncology.
New Mayo Clinic research suggests up to 97 percent of patients are comfortable with their health care provider asking sexual orientation and gender identity questions. Before this research, it was unclear if the questions – which researchers say are important to reduce health disparities among LGBTI patients – would offend patients. The findings were published today in Health Services Research.
VR has shown promise in several clinical trials assessing its possible utility as a distraction tool to alleviate pain and distress during medical procedures.
Working with mice, Johns Hopkins researchers report they have found previously known skin itch receptors in the airways that appear to contribute to bronchoconstriction and airway hypersensitivity, hallmarks of asthma and other respiratory disorders. The investigators’ experiments in mice suggest that the receptors’ activation directly aggravates airway constriction and—if the same process is active in people—may be a promising new target for the development of drug therapies.
Research from a collaborative team at Washington University in St. Louis tested a 3-D method that could lead to new diagnostic tools that will precisely measure the third-trimester growth and folding patterns of a baby’s brain. Their findings might help to sound an early alarm on developmental disorders in preemies that could affect them later in life.
According to a new study by The Wistar Institute, EZH2 inhibitors that are currently in clinical development for hematological malignancies and solid tumors may be effectively targeted to epithelial ovarian cancers overexpressing the CARM1 protein.
A mix of factors is contributing to an increasing mortality rate of trees in the moist tropics, where trees in some areas are dying at about twice the rate that they were 35 years ago.
New research published in Science (March 9), C. Austen Angell of Arizona State University and colleagues from the University of Amsterdam have observed one of the more intriguing properties predicted by water theoreticians – that, on sufficient super-cooling and under specific conditions it will suddenly change from one liquid to a different one.
A new study has found that although radiology research by women has increased significantly over the past five decades, the rate of this increase has leveled off since 2000.
Mandatory flu vaccines for health care workers improve participation by as much as 30 percent and reduce absenteeism during critical periods of patient surges by about 6 percent, findings from a multi-institutional study show.
A new study indicates that the kinds of microbes living in the gut influence the severity and recurrence of parasitic worm infections in developing countries. The findings, by researchers at Washington University School of Medicine in St. Louis, suggest that manipulating the gut’s microbial communities may protect against intestinal parasites, which affect more than 1 billion people worldwide.
The Toxicological Sciences 20th anniversary celebration continues with articles on mitochondrial toxicity and organophosphorus compounds, in addition to featured papers on metabolic syndrome; paternal exposures and offspring’s mitochondria; data fusion and AOPs; DNA damage assay predictability; and imaging mammary epithelial organoids.
A new study by scientists from WCS (Wildlife Conservation Society) and other groups predicts that the effects of climate change will severely impact the Albertine Rift, one of Africa’s most biodiverse regions and a place not normally associated with global warming.
Highlights • Between 2005 and 2015, the unadjusted rate of living kidney donation in the United States was 30.1 and 19.3 per million population in women and men, respectively. • After adjusting for differences in age, race, the incidence of kidney failure, and geographic factors, the incidence of donation was 44% higher in women. • Over time, the incidence of donation was stable in women but declined in men. The decline was most marked in men from lower income groups.
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