Feature Channels: Aging

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Launching no earlier than March 6 at 11:50 PM EST, the Johns Hopkins University will send heart muscle tissues, contained in a specially-designed tissue chip the size of a small cellphone, up to the microgravity environment of the International Space Station (ISS) for one month of observation.

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Daylight saving is approaching again, perhaps for the penultimate time in some countries where a fierce debate is being waged over its impact on health and the economy.

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Researchers know that the protein tau develops into tangles in the brains of people with Alzheimer’s disease. But until now they have struggled to understand what factors make you more or less likely to develop these tangles. In a preliminary study released today that will be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto, Canada, April 25 to May 1, 2020, researchers say that they have identified gene variants that are associated with a susceptibility to developing tau deposits in older age.

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Chronic pain affects a large proportion of older adults and most long-term care residents. Managing chronic pain effectively is essential but challenging, and it has been complicated by concerns about opioid abuse.

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Older people who experience daytime sleepiness may be at risk of developing new medical conditions, including diabetes, cancer and high blood pressure, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto, Canada, April 25 to May 1, 2020.

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Adults 65 and older on the DASH diet with a perscribed protein intake not only maintained muscle mass and strength, but also improved their metabolic health.

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Older adults often face new disabilities after a hospital stay for a serious illness.

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"For those who have faced exploitation and discrimination at the hands of physicians, the medical profession, and medical institutions, trust is a tall order and, in many cases, would be naïve," writes Laura Specker Sullivan in "Trust, Risk, and Race in American Medicine."

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Cannabis use continues to increase in popularity among adults 65 years of age and older in the United States, according to a new study from NYU Grossman School of Medicine.

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UT Physicians, HCPC, Memorial Hermann, LBJ Hospital earn age-friendly recognition

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Millions of people might eventually be spared the embarrassment and extreme isolation caused by wetting themselves, thanks to new research.

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From working to develop one of the first nonhuman primate models for the 2019 novel coronavirus disease (COVID-19) to designing new nanotechnology-based tests to rapidly diagnose infections, researchers at Tulane University are responding across disciplines to the emerging coronavirus epidemic.

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Scientists at Sanford Burnham Prebys Medical Discovery Institute and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell’s nucleus—and identified an FDA-approved drug that helped suppress the damaging effects of the condition in cells and mice. The discovery, published in Genes & Development, could lead to treatments that promote healthy aging or prevent age-associated diseases such as cancer, Alzheimer’s disease, heart disease and more.

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Few studies have examined how the neighborhood’s physical environment relates to cognition in older adults. Researchers categorized 4,716 individuals by apolipoprotein E (APOE) genotype – a genetic risk factor for Alzheimer’s disease (AD) to determine if there are cognitive benefits of living in neighborhoods with greater access to social, walking and retail destinations. Results showed that the positive influence of neighborhood environments on cognition are strongest among those who are at the lowest risk for AD, specifically APOE ε2 carriers.

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The Endocrine Society today announced an update to its osteoporosis Clinical Practice Guideline to include recommendations for romosozumab, a new medication that was approved last year to treat postmenopausal women at high risk of fracture.

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Today, at a European Parliament lunch debate hosted by Christophe Hansen MEP (Luxembourg), Alzheimer Europe launched a new report presenting the findings of its collaborative analysis of recent prevalence studies and setting out updated prevalence rates for dementia in Europe.

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With the support of a recent $3 million grant renewal from the National Institute on Aging (NIA), Mariana Figueiro is perfecting a treatment she developed for older adults with Alzheimer’s disease and related dementias that helps to regulate sleep and reduce symptoms of depression — and requires no drugs, only light.

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A forma em que o sistema vascular envelhece e o ritmo ao qual a aterosclerose, o enrijecimento das paredes arteriais ou o acúmulo de bloqueios arteriais, progride diferem entre homens e mulheres. Essas diferenças relacionadas ao sexo e à idade afetam diretamente o risco de desenvolver doença vascular nas mulheres.

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Les hommes et les femmes diffèrent dans le vieillissement de leurs systèmes vasculaires et dans la vitesse de progression de l’athérosclérose, le durcissement des parois artérielles ou l'accumulation d'obstructions dans les artères. Ces différences liées au sexe et à l'âge impactent directement le risque qu'une femme développe une maladie cardiovasculaire.

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Researchers at UC San Diego School of Medicine report that abnormal levels of beta-amyloid plaques in brain predict cognitive decline and higher risk of developing Alzheimer’s disease, but also that cognitive performance predicts progression from normal to abnormal levels of beta-amyloid.

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Consumption of cocoa may improve walking performance for patients with peripheral artery disease, according to the results of a small, preliminary, phase II research trial published today in the American Heart Association's journal Circulation Research.

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Researchers have lifted fertility rates in older female mice with small doses of a metabolic compound that reverses the ageing process in eggs, offering hope for some women struggling to conceive.

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Women aged 50-70 are more likely than younger women to consume alcohol at levels that exceed low risk drinking guidelines - and most think that's just perfectly fine.

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Men who are taller in young adulthood, as an indicator of early-life circumstances, may have a lower risk of dementia in old age, suggests a study published today in eLife.

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UC San Diego and IBM researchers reveal a new understanding of how our microbiomes change as we age, setting the stage for future research on the role microbes play in accelerating or decelerating the aging process and influencing age-related diseases.

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By the time they reach menopause — which officially begins one year after a woman’s last period — many women think they have their lives figured out. Careers are well established; children are grown and independent; and there’s more time for leisure and self-care. Yet many women in their 40s and 50s are surprised to suddenly notice changes on their skin, including acne and age spots. Fortunately, dermatologists from the American Academy of Dermatology say that while many of these changes are inevitable due to hormones, there is a lot women can do at home to lessen these effects.

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Dr. Chen Hou and his research collaborators have found an answer to the decades-old question of why naked mole-rats with high oxidative damage live 10 times longer than mice of comparative weight.“The long lifespan of the East African naked mole-rats raises one of the most serious paradoxes in the study of aging,” says Hou, an associate professor of biological sciences at Missouri S&T.

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UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.

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Researchers at Wake Forest School of Medicine have received a five-year grant worth approximately $2.53 million from the National Institute on Aging to evaluate whether a novel brain-imaging technique can identify Alzheimer’s disease in its early stages.

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Is it possible to investigate menopausal age, or not? In more than one in three women aged 50, the body provides no clear answer about the menopause, a University of Gothenburg study shows. Increased use of hormonal intrauterine devices and contraceptive pills are the cause.

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Health insurance costs weigh heavily on the minds of many middle-aged adults, and many are worried for what they’ll face in retirement or if federal health policies change, according to a new study. More than a quarter of people in their 50s and early 60s lack confidence that they’ll be able to afford health insurance in the next year, and the number goes up to nearly half when they look ahead to retirement.

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New research at Trinity College Dublin, published today (Thursday, February 6th, 2020), shows that the number of people dying in Ireland with palliative care needs will increase 84% to 2046.

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Scientists have found a way to distinguish between two progressive neurodegenerative diseases, Parkinson’s disease (PD) and multiple system atrophy (MSA), using a technology developed by a researcher at UTHealth. The discovery was published today in Nature.

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Researchers at University of California San Diego School of Medicine, in collaboration with Mather Institute, developed a method to enhance resilience and reduce subjective stress in residents living in senior housing communities.

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ISPOR--The Professional Society for Health Economics and Outcomes Research has released its third annual "Top 10 Health Economics and Outcomes Research (HEOR) Trends" report. The full report is available at www.ispor.org/top10trends.

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People who eat or drink more foods with the antioxidant flavonol, which is found in nearly all fruits and vegetables as well as tea, may be less likely to develop Alzheimer’s dementia years later, according to a study published in the January 29, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Researchers at Albany Medical College in New York have discovered that a specific type of immune cell accumulates in older brains, and that activating these cells improves the memory of aged mice. The study, which will be published February 5 in the Journal of Experimental Medicine (JEM), suggests that targeting these cells might reduce age-related cognitive decline and combat aging-associated neurodegenerative disease in humans.

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Dr. Kyong Hee Chee’s research interests include aging and the life course and community development.

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Evaluating the effectiveness of therapies for neurodegenerative diseases is often difficult because each patient’s progression is different. A new study shows artificial intelligence (AI) analysis of blood samples can predict and explain disease progression, which could one day help doctors choose more appropriate and effective treatments for patients.

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Researchers at Beth Israel Deaconess Medical Center (BIDMC) have found that orthostatic hypotension was not associated with higher risk of cardiovascular events, falls, or fainting among participants in The Systolic Blood Pressure Intervention Trial. In a study published in the journal Hypertension, the scientists showed that hypertension treatment had no impact on the link between OH and cardiovascular outcomes or other adverse events.

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Reporters are invited to attend The Allied Genetics Conference (TAGC), to be held April 22-26, 2020 in National Harbor, Maryland, just 30 minutes from downtown Washington DC. TAGC 2020 will feature the latest discoveries from researchers at the leading edge of what is possible in the biological and biomedical sciences.

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Family caregivers usually are not asked by health care workers about needing support in managing older adults’ care, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

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If you're having difficulty identifying the right word to express yourself clearly or remembering a story correctly, you may blame menopause.

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People who regularly care for or assist a family member or friend with a health problem or disability are more likely to neglect their own health, particularly by not having insurance or putting off necessary health services due to cost, according to a study published by the American Psychological Association.

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Many Medicare patients with new episodes of low back pain receive care inconsistent with current guidelines – including high use of opioids and advanced imaging tests, reports a study in the February issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.

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Wide swings in blood pressure readings among young adults are associated with a higher risk of cardiovascular disease by middle age, a new analysis led by Duke Health researchers shows. The finding, publishing Jan. 22 in JAMA Cardiology, suggests that the current practice of averaging blood pressure readings to determine whether medications are necessary could be masking a potential early warning sign from the fluctuations themselves.

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It would be the first treatment for "dry" age-related macular degeneration and could significantly improve treatment for wet AMD.

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The Council on Foreign Relations (CFR) introduces Think Global Health, a multi-contributor website that examines how changes in health are reshaping economies, societies, and the everyday lives of people around the world.