Doctors may one day be able to gauge a patient's risk of dementia with an MRI scan, according to a new study from Washington University School of Medicine in St. Louis and the University of California San Francisco. Using a new technique for analyzing MRI data, researchers were able to predict who would experience cognitive decline with 89 percent accuracy.
A new frontier in the science of circadian rhythms – whose disruption is linked to major diseases like cancer and diabetes – suggests a previously unknown mechanism at work in our daily biological cycle.
University of Iowa music therapist PhD student Alaine E. Reschke-Hernández planned and facilitated a study in four Iowa nursing homes to examine the effectiveness of a music therapy intervention with people with Alzheimer’s or related dementias.
Research is starting to connect the dots between Alzheimer's disease and epilepsy. What does the future hold?
Rong Xu, PhD, recently received a total of $5 million for two projects that will use big data methods for a comprehensive look at a range of factors that may inform the mechanism of Alzheimer’s and related dementia.
In the largest genetic study of Alzheimer's disease, researchers at the University of California, San Francisco and Washington University School of Medicine in St. Louis, have found that genes that increase risk of cardiovascular disease also heighten the risk for Alzheimer’s.
Like humans, fruit flies are active during the day, sleep at night and have similar sleep characteristics. A study has discovered a new gene and uncovered a mechanism that modulates sleep by controlling the movement of taurine – a common ingredient found in many energy drinks like Red Bull™ – into neuron cells of the fly brain. Taurine also is abundant in the human brain and is consistently elevated in blood and urine of sleep-deprived people.
Research from the UK Sanders-Brown Center on Aging has identified two potential ways to predict VCID – the second leading cause of dementia behind Alzheimer's disease
Landmarks across the country and around the world will light up teal on November 8th to raise Alzheimer’s awareness as part of the Alzheimer’s Foundation of America’s (AFA) Light the World in Teal program. The annual program, held in November for Alzheimer’s Awareness Month, aims to literally shine a spotlight on Alzheimer’s disease and show support for the millions of people affected by it.
A new study out of the Krembil Brain Institute, part of the Krembil Research Institute, suggests drinking coffee may protect you against developing both Alzheimer’s and Parkinson’s disease.
Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer’s and Parkinson’s diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries. Stem cell transplantation, which shows promise as a treatment for central nervous system diseases, has been hampered by low cell survival rates, incomplete differentiation of cells and limited growth of neural connections.
People with Alzheimer’s disease who were treated with diabetes drugs showed considerably fewer markers of the disease—including abnormal microvasculature and disregulated gene expressions—in their brains compared to Alzheimer’s patients without treatment for diabetes, Mount Sinai researchers report.
Throughout November, let us not just create awareness about the problem of Alzheimer’s disease. Let’s commit to finding solutions, to providing greater support for the millions of Americans living with Alzheimer’s disease or caring for someone who has it, and to work harder than ever to find the cure that so many are desperately waiting for. Let’s create hope
The American Society for Biochemistry and Molecular Biology announced today that Kerry-Anne Rye of the University of New South Wales Sydney and Nicholas O. Davidson of Washington University in St. Louis will be the next editors-in-chief of the Journal of Lipid Research.
New Vanderbilt research finds how long humans and other warm-blooded animals live—and when they reach sexual maturity— may have more to do with their brain than their body. More specifically, it is not animals with larger bodies or slower metabolic rates that live longer; it is animals with more neurons in the cerebral cortex, whatever the size of the body.
Nearly 6 million Americans are living with Alzheimer’s disease and 16.1 million Americans provide unpaid care for people with Alzheimer’s or other dementias, accounting for an estimated 18.4 billion hours of care. As part of Alzheimer’s Awareness Month in November, UAB geriatricians provide tips, ideas and best practices to help family caregivers care for a loved one living with Alzheimer’s or dementia, while also keeping the patient and the caregiver safe and sane. The tips include ways to talk about major decisions, such as taking away the keys or moving someone to a new home, as well as ideas to allow the patient to stay safe while continuing to live with dignity and feel valued in their community.
The Alzheimer’s Foundation of America (AFA) is encouraging individuals to be proactive about their brain health and wellness by getting a free, confidential memory screening this November as part of Alzheimer’s Awareness Month and National Memory Screening Month.
The National Institute on Aging, part of the National Institutes of Health, has awarded researchers at NYU Rory Meyers College of Nursing a $6.1 million grant to study a program designed to bring effective care to people with dementia receiving hospice care. The two-phase, five-year grant will fund the first large-scale clinical trial of people with dementia in hospice and their caregivers.
Results from two studies show that a new, non-invasive imaging device can see signs of Alzheimer’s disease in a matter of seconds. The researchers show that the small blood vessels in the retina at the back of the eye are altered in patients with Alzheimer’s.
• Patients with acute kidney injury had more than a 3-fold higher risk of developing dementia compared with those without acute kidney injury during a median follow-up time of 5.8 years. • Results from the study will be presented at ASN Kidney Week 2018 October 23–October 28 at the San Diego Convention Center.
In this issue, find research on infant sugary drink consumption, China's top 20 health challenges, aging and healthy years in the Netherlands, and increasing opioid use in Massachusetts
Audio from the American Neurological Association’s 143rd Annual Meeting media roundtable, held October 22, 2018, is now available. At the roundtable, presenters of the meeting’s six principal symposia presented highlights, discussed the relevance of the work, and answered questions.
The Alzheimer's Drug Discovery Foundation (ADDF) is saddened to hear the news that former Supreme Court Justice Sandra Day O'Connor released a letter today saying she has been diagnosed with the beginning stages of dementia, probably Alzheimer's disease.
As the keynote speaker for the American Neurological Association's Presidential Symposium, “Lewy Body Dementia (LBD): From Symptoms to Synuclein,” Susan Schneider Williams put a human face on the leading-edge science presented at the session.
For the first time, the American Neurological Association’s 143rd Annual Meeting will feature a media roundtable TODAY, October 22, 2018 from 11:50-1:00 p.m. at which presenters of the six principal symposia will present highlights, discuss the relevance of the work, and answer questions.
Embargoed abstracts to be presented at the American Neurological Association’s 143rd Annual Meeting October 21-23, 2018 at the Hyatt Regency Atlanta are now available to journalists upon request.
Methods to more precisely inject stem cells into the spinal cord; an enzyme that enhances the synthesis of dopamine in people with Parkinson’s disease; a drug that protects against chemotherapy-induced neuropathy – these are just a few of the exciting research findings that will be presented at the American Neurological Association’s 143rd Annual Meeting October 21-23, 2018 at the Hyatt Regency Atlanta.
Investigators at the West Virginia University Rockefeller Neuroscience Institute performed the first procedure in the world of a phase II trial using focused ultrasound to treat a patient with early stage Alzheimer’s.
In a report of the phase II ADvance clinical trial, Johns Hopkins researchers report that people diagnosed under age 65—those with early-onset Alzheimer’s disease—didn’t benefit from deep brain stimulation. Their findings appeared in the July issue of the Journal of Alzheimer’s Disease.
A multidisciplinary, international group of experts has recommended changing the way clinicians and patients describe cognitive changes experienced in some patients after anesthesia and surgery. The recommendations are being published simultaneously in six peer-reviewed journals including, Anesthesiology.
Stiffness of the aorta – more so than blood pressure or subclinical brain disease – is a key risk factor for dementia. Since aortic stiffness can be reduced by medication and healthy lifestyle changes, these results suggest that people can still lower their dementia risk well into old age.
For the first time, the American Neurological Association’s 143rd Annual Meeting will feature a media roundtable on Monday, October 22, 2018 from 11:50-1:00 p.m. at which presenters of the six principal symposia will present highlights, discuss the relevance of the work, and answer questions. To RSVP for the media roundtable and request dial-in information if you are not able to attend in person, please contact Rachel Brown at [email protected].
Researchers from three Milwaukee-area universities have developed a “stripped-down” estrogen molecule that improves memory in an animal model of post-menopausal dementia, kickstarting new drug discovery for treating memory loss in women.
People with a particular kind of irregular heartbeat called atrial fibrillation may experience a faster decline in thinking and memory skills and have a greater risk of dementia than those without atrial fibrillation, according to a study published in the October 10, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers present comprehensive genome-wide map of RNA splicing variation in aging brain – novel insights could offer new strategies for diagnosis and treatment of Alzheimer’s disease
Researchers at University of California San Diego School of Medicine, with collaborators across the country, report that people who participate in dementia prevention trials are primarily motivated by altruism and pleased to help.
What you need to know before doing genetic testing
A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components. The method offers a potential new means for illuminating the physical properties of unhealthy cells, such as those linked to Alzheimer’s and Parkinson’s disease.
Two UVA Darden School of Business alumni with similar career trajectories, including formative years spent in Silicon Valley before returning to India, are playing key roles in the country’s growth and maturation, offering a front-row perspective on the changes sweeping the country.
The National Institute of Dental and Craniofacial Research and National Institute on Aging have awarded the NYU Rory Meyers College of Nursing with funding to improve the oral hygiene of people with mild dementia. The $3.47 million, five-year grant will be used to implement and study a unique oral health intervention involving family caregivers in New York and North Carolina.
Connecting patients, caregivers and family members with resources and research is the goal behind an annual public conference hosted by the Arizona Alzheimer’s Consortium.
Long-term exposure to periodontal disease bacteria causes inflammation and degeneration of brain neurons in mice that is similar to the effects of Alzheimer’s disease in humans. Periodontal disease may be an initiator of Alzheimer’s.
Two UT Southwestern faculty members have been awarded prestigious National Institutes of Health (NIH) Director’s New Innovator Awards for high-risk, high-reward research.
A new poll shows that only a small percentage of people in their 50s and early 60s have had their DNA tested – either for medical reasons, to learn their ancestry or out of curiosity – but far more have an interest in getting tested. However, two thirds said genetic testing could lead them to worry too much about their future health.
The National Institute on Aging has awarded scientists at University of California San Diego School of Medicine and San Diego State University with a five-year, $4 million grant to boost the number of Latino and other underrepresented minority researchers studying Alzheimer’s disease and related dementias afflicting seniors of Latino origins, a demographic historically overlooked.
Georgetown University Medical Center announces a clinical trial for neurodegenerative disorder Huntington’s disease with the repurposed cancer drug nilotinib.
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