Pediatric cancer researchers at The Children’s Hospital of Philadelphia contributed important expertise to a new landmark study of medulloblastoma, a type of brain tumor typically found in children.
A mathematically driven evolutionary snapshot of woody plants in four similar climates shows that genetic diversity is more sensitive to extinctions and loss of habitat them than long thought.
An effort to increase biofuel production has led scientists to discover genes in yeast that improve their tolerance to ethanol, allowing the production of more ethanol from the same amount of nutrients. This study shows how genetically altered yeast cells survive higher ethanol concentrations, addressing a bottleneck in the production of ethanol from cellulosic material (nonfood plant sources) in quantities that could compete economically with fossil fuels.
Investigators from New Jersey’s only NCI-designated Comprehensive Cancer Center have presented new research at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium. Their work highlights how a variation in a person’s DNA sequence is associated with an earlier age of onset for breast cancer that is stimulated by the hormone estrogen.
Using a new gene sequencing method, a team of researchers led by scientists from Johns Hopkins and the National Institutes of Health has discovered a gene that appears to cause some instances of familial amyotrophic lateral sclerosis (ALS). The finding could lead to novel ways to treat the more common form of this fatal neurodegenerative disease, which kills the vast majority of the nearly 6,000 Americans diagnosed with ALS every year.
Cancer researchers have identified six gene markers present in early stage non-small cell lung cancer (NSCLC) that show promise in helping oncologists better identify which tumors will relapse after curative surgery, according to a study presented at the 2010 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO), the International Association for the Study of Lung Cancer (ISLAC) and the University of Chicago.
In women who test positive for BRCA 1/2 mutations associated with a high risk of breast or ovarian cancer, some key psychological factors influence the decision to undergo risk-reducing surgery, reports the December Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics (ACMG).
Mandatory genetic screening of newborns for rare diseases is creating unexpected upheaval for families whose infants test positive for risk factors but show no immediate signs of the diseases, a new UCLA study warns.
Scientists at Albert Einstein College of Medicine of Yeshiva University have made an unexpected finding about the method by which certain genes are activated. Contrary to what researchers have traditionally assumed, genes that work with other genes to build protein structures do not act in a coordinated way but instead are turned on randomly. The surprising discovery, described in the December 5 online edition of Nature Structural and Molecular Biology, may fundamentally change the way scientists think about the way cellular processes are synchronized.
Male mice born with a genetic mutation that’s believed to make humans more susceptible to schizophrenia develop behaviors that mimic other major psychiatric illnesses when their mothers are exposed to an assault to the immune system while pregnant, according to new Johns Hopkins research.
Personalized medicine centers on being able to predict the risk of disease or response to a drug based on a person’s genetic makeup. But a study by scientists at Washington University School of Medicine in St. Louis suggests that, for most common diseases, genes alone only tell part of the story. Their research shows the environment interacts with DNA in ways that are difficult to predict, even in simple organisms like single-celled yeast.
A new study offers hope for children born with a rare genetic disease, according to a paper published by the American Association for the Advancement of Science.
An international team has identified a gene that appears to be an important switch in determining whether the biological program for the development of gender will go according to plan, or if, when mutated, will cause a glitch in the program.
A large genetic study of people with major depression has found that a duplicated region of DNA on chromosome 5 predisposes people to the disorder. The gene at that site influences nerve cell development.
UT Southwestern Medical Center researchers have identified a gene responsible for a rare disease that results in severe joint stiffness, muscle loss, anemia and panniculitis-induced lipodystrophy, or JMP syndrome.
So, he or she has cheated on you for the umpteenth time and their only excuse is: “I just can’t help it.” According to researchers at Binghamton University, they may be right. The propensity for infidelity could very well be in their DNA.
The fragile regions in mammalian genomes that are thought to play a key role in evolution go through a "birth and death" process, according to new bioinformatics research performed at the University of California, San Diego. The new work, published in the journal Genome Biology on November 30, could help researchers identify the current fragile regions in the human genome – information that may reveal how the human genome will evolve in the future.
Whitehead Institute researchers have shown in mouse models that overexpression of the microRNA 125b (miR-125b) can independently cause leukemia and accelerate the disease’s progression in mice.
Researchers have identified a novel geneon chromosome 15q that, when altered, causes nemaline myopathy with cores, a rare inherited muscle disorder.
Playing online can mean more than killing time, thanks to a new game developed by a team of bioinformaticians at McGill University. Now, players can contribute in a fun way to genetic research.
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