The year 2020 can be summarized simply by one word - COVID-19 - as it was the culprit that froze the entire world. For more than 8 months so far, movement between nations has been paralyzed all because there are no means to prevent or treat the virus and the diagnosis takes long.
SEATTLE — Oct. 5, 2020 — Fred Hutchinson Cancer Research Center announced the opening of the COVID-19 Clinical Research Center, or CCRC. Funded by philanthropic donations and public/private partnerships, the CCRC is one of the first stand-alone facilities in the nation designed to test novel interventions to treat and prevent COVID-19.
Not only might cannabis users require more anesthesia during surgery than non-users, they may have increased pain afterwards and use higher doses of opioids while in the hospital, suggests first-of-its kind research being presented at the ANESTHESIOLOGY® 2020 annual meeting.
Eppendorf, a leading life science company, announces that its Americas Market Region Commercial headquarters officially moved from Hauppauge, NY to Framingham, MA.
The American College of Surgeons Clinical Congress 2020 (Oct. 3-7) is a virtual-only event. Here’s the listing of next week’s activities for media attendees.
Seven of 10 adults with appendicitis can safely avoid surgical removal of their appendix (appendectomy) for at least several months by receiving a course of antibiotics.
Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of Drugs and Appendectomy (CODA) trial.
A multinational clinical trial of for the treatment of Niemann-Pick disease Type C (NPC) demonstrated a statistically significant and clinically meaningful improvement in symptoms, functioning, and quality of life in both primary and topline secondary endpoints for both pediatric and adult patients with NPC.
Artificial intelligence (AI) used in machine learning models can predict which patients are at highest risk for severe pain after surgery, and help determine who would most benefit from personalized pain management plans that use non-opioid alternatives, suggests new research being presented at the ANESTHESIOLOGY® 2020 annual meeting.
New research presented at the virtual American College of Surgeons Clinical Congress 2020 reports that opioid guidelines may be missing a small group of patients that need a greater level of pain control.
Almost 20 years into the opioid epidemic, there finally is evidence of significant and continual decreases in the abuse of these risky pain medications, according to an analysis of national data being presented at the ANESTHESIOLOGY® 2020 annual meeting.
Drugs to lower blood pressure of the type ACE inhibitors or angiotensin II receptor blockers reduce the mortality rate of influenza and pneumonia.
University at Buffalo researchers have received a grant from the Community Pharmacy Foundation to help add community health workers to pharmacies to better connect patients to critical services and lower health care costs.
The immunotherapy drug atezolizumab improves survival over standard chemotherapy for many patients with newly diagnosed non-small cell lung cancer, according to a new study led by Yale Cancer Center researchers.
Rutgers researchers have reported an increased mortality risk in adults with depression who initiated augmentation with newer antipsychotic medications compared to a control group that initiated augmentation with a second antidepressant.
In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia, a brain disorder commonly known as “lazy eye.”
Clinical trial shows health care workers in contact with COVID-19 patients who took hydroxychloroquine each day did not reduce their rate of infection
Women and racial minorities are seriously underrepresented in trials of medicines for alcohol use disorder (AUD) despite evidence that these treatments affect demographic groups differently. This is according to a review in Alcoholism: Clinical & Experimental Research, which may be the first to evaluate sex and racial representation in studies relating to the three pharmacological treatments approved by the Food and Drug Administration (FDA) for AUD. Previous research indicates that sex and race/ethnicity likely influence the prevalence of AUD, its risk of health consequences, and the effectiveness of treatments.
Recreational use of the illicit drug methamphetamine has long been associated with increases in overall impatient and risky behavior. Now, a new study by Johns Hopkins Medicine researchers affirms that meth use increases not only sexual desire but also, specifically and measurably, the risk of casual sex without a condom for those who have an increase in sexual desire.
October is National Dental Hygiene Month, and ADHA and Colgate have partnered to celebrate dental hygienists.
Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturised antibodies, opening the way for a potential new class of treatments for diseases.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Parkinson’s disease is most commonly treated with levodopa, but the benefits wear off as the disease progresses and high doses can result in dyskinesia, which are involuntary and uncontrollable movements. To better understand the underlying reasons behind these effects, researchers created a model of the interactions between levodopa, dopamine, and the basal ganglia, an area of the brain that plays a crucial role in Parkinson’s disease. They discuss their findings in the journal Chaos.
Approvals of prescription opioids by the U.S. Food and Drug Administration over more than two decades have been based on evaluations in narrowly defined patient groups for which certain safety-related outcomes have been rarely systematically assessed, according to a new analysis from researchers at the Johns Hopkins Bloomberg School of Public Health.
UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries. The findings, which were published today in Nature Cell Biology, could lead to better therapies for patients with lung disease, including acute respiratory distress syndrome (ARDS) due to COVID-19.
A combination antibody treatment for preventing COVID-19 illness in individuals who have had sustained exposure to someone with the virus is being studied by researchers at The University of Texas Health Science Center at Houston (UTHealth). The clinical trial is enrolling patients at Harris Health System’s Lyndon B. Johnson Hospital.
The NIH has awarded NYU College of Dentistry researchers Nigel Bunnett, PhD, and Brian Schmidt, DDS, MD, PhD, a $3.9 million grant to study targeting endosomal receptors for the treatment of chronic pain. The five-year grant will support Bunnett and Schmidt’s collaborative research, which aims to ultimately yield improved pain management without the need for opioids.
Escherichia coli, known as E. coli, are bacteria which many people associate with causing mild food poisoning, but some types of E. coli can be fatal.
Según una investigación de Mayo Clinic en la que participaron 667 pacientes que recibieron trasplante pulmonar entre el 2005 y el 2018, los medicamentos antimicóticos preventivos reducen a la mitad el riesgo de mortalidad en el primer año luego del trasplante de pulmón.
DALLAS – Sept. 24, 2020 – Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes – parasitic flatworms that cause the little-known tropical disease schistosomiasis. The findings, published online today in Science, could change the course of this disease that kills up to 250,000 people a year.
The University of New Hampshire will receive $1.8 million from the National Institutes of Health (NIH) that will further molecular research to better understand drug interactions at the cellular level and help lead to the development of new targeted drugs to treat wide-spread metabolic, growth, neurological and visual disorders including diabetes and cancer.
Researchers have sequenced the genome of Alexander Fleming's penicillin mould for the first time and compared it to later versions.
The University of Texas MD Anderson Cancer Center and Taiho Pharmaceutical Co., Ltd., today announced a three-year strategic collaboration to accelerate the development of treatments for significant unmet medical needs in oncology, including patients with brain metastases and those with cancers refractory to available therapies.
Supplements that claim to improve mental focus and memory may contain unapproved pharmaceutical drugs and in potentially dangerous combinations and doses, according to a new study published in the September 23, 2020, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology. Researchers found five such drugs not approved in the United States in the supplements they examined. The supplements are sometimes called “nootropics,” “smart drugs” or “cognitive enhancers.”
Gary Corbin, 63, dropped a heavy hurricane window shutter, which gashed his leg before it hit the ground. After wintering in Florida, this resident of Grosse Pointe Farms had been helping his significant other close down her Palm Beach Gardens home before they returned to Michigan in mid-June. He treated the wound and kept it covered on the drive north.
Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why.
Patients taking drugs called NRTIs to treat HIV and hepatitis B had a 33% lower risk of developing diabetes.
Antifungal preventive medications reduce mortality risk by half in the first year following lung transplantation, according to Mayo Clinic research involving 667 patients who received lung transplants from 2005 to 2018.
Pills are being sent into space to test how they cope with the rigours of one of the harshest environments known. The University of Adelaide is studying how exposure to microgravity and space radiation affects the stability of pharmaceutical tablet formulations. Two separate missions will send science payloads into orbit around Earth: the first will test how tablets cope with the environment inside the International Space Station (ISS) U.S. National Laboratory. The second mission scheduled for early 2021, will test how tablets cope outside the ISS.
In this research, the investigators studied the effect of TDF/FTC in patients who were using the drug to prevent HIV, and in the absence of active HIV infection. The researchers observed patients over the past five years and also included data from two earlier studies.
Toxicological Sciences features leading research in toxicology in the areas of biomarkers, environmental toxicology, and more in the September 2020 issue.
Researchers in China have discovered a potential way to prevent a lack of oxygen or blood flow from causing long-lasting brain damage in newborn children. The study, which will be published September 29 in the Journal of Experimental Medicine (JEM), suggests that targeting the histamine H2 receptor with drugs already used to treat acid reflux in infants could help newborns recover from hypoxic-ischemic encephalopathy (HIE), a condition that affects over 1 in 1,000 live births and can cause life-long neurological disabilities.
LONDON (Sept. 21, 2020) — The Cure Parkinson’s Trust (CPT) and Van Andel Institute (VAI) are delighted to welcome a third strategic funding partner, The John Black Charitable Foundation (JBCF), to the International Linked Clinical Trials (iLCT) program. Together, these three partners have pledged a total of US$6.75 million to Parkinson’s research over three years.
The October edition of SLAS Discovery features the cover article, “A Critical and Concise Review of Mass Spectrometry Applied to Imaging in Drug Discovery” by Richard J. A. Goodwin Ph.D. (AstraZeneca), Zoltan Takats Ph.D. (Imperial College London), and Josephine Bunch, Ph.D. (National Physical Laboratory).
Despite the impact of the COVID-19 pandemic across the globe, there has been a resurgence of interest in immuno-oncology (I-O) preclinical and clinical development, bringing hope to cancer patients and physicians who treat them.
For the first time, scientists at UNC-Chapel Hill and Stanford solved the high-resolution structure of psychedelic drugs bound to the 5-HT2A serotonin receptor, a major step toward understanding how the drugs cause such wild effects and how they might be better used to treat psychiatric conditions.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right