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Medicine

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Dementia, Lewy Body Dementia, Parkinson's Disease, REP, Parkinsonism, Rochester Epidemiology Project

Study Offers Answers on Life Expectancy for People with Parkinson’s Disease, Lewy Body Dementia

Faced with a serious disease, patients want to know the answer to a difficult question: “How long will I live?”

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Stem Cell Trial for Stroke Patients Suffering Chronic Motor Deficits Begins at UTHealth

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A clinical trial to evaluate the safety and efficacy of a stem cell product injected directly into the brain to treat chronic motor deficits from ischemic stroke has begun at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

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Spinal Muscular Atrophy: New Clues to Cause and Treatment

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Spinal muscular atrophy is partly due to defects in the sensory neuron synapses that activate motor neurons. Symptoms may be reduced by improving synapse function.

Medicine

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ALS, Gene, Lou Gehrig disease, Developmental Biology

New Gene Identified in Lou Gehrig’s Disease

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For the first time, a variant in UBQLN4 gene has been associated with Lou Gehrig’s disease or amyotrophic lateral sclerosis (ALS) – a progressive disease resulting in the loss of nerve cells that control muscle movement, which eventually leads to paralysis and death. The study published in the journal eLife also describes how this gene variant disrupts a cellular process that drives motor neuron development. This new insight opens the door to potential treatment targets for ALS.

Medicine

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Neurosurgery, MR-guided focused ultrasound, Essential Tremor, InSightec

Pennsylvania Hospital Neurosurgeons Perform the First High-Intensity Focused Ultrasound Treatment for Essential Tremor in Pennsylvania

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John Lukens recently became the first patient in Pennsylvania to receive MR-guided Focused Ultrasound Treatment (MRgFUS) for Essential Tremor (ET). At age 61, Lukens has suffered with bilateral Essential Tremor for roughly 10 years – a condition which left him with such significant shaking in his hands and arms that eating, shaving, and even writing with his dominant hand was very difficult. Now two weeks after the procedure, Lukens, who lives in Plymouth Meeting, Pa., says he’s tremor-free in his right hand.

Medicine

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Alzheimer's Disease, National Institute for Aging, National Institutes For Health

Penn Medicine’s Alzheimer’s Genetics Data Storage Site Receives Five-Year Renewal to Total $7.7 Million

Penn Medicine’s Alzheimer’s disease genetics data repository has received a five-year funding renewal from the National Institute on Aging (NIA) of the National Institutes of Health. The award is expected to total $7.7 million over five years.

Medicine

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smartphone applications, smartphone app, senior citizens health, Senior Care, mobility research, Centers For Disease Control, Healthcare, personalized medicine, personalized care, Stroke Prevention

Personal Mobility Phone App Suite Can Help Inform Physician Diagnoses

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A new suite of phone apps developed at The University of Alabama in Huntsville (UAH) uses Android smart phones to monitor the physical mobility and stability of older people.

Medicine

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Aspirin, Atrial fibrilation, Bleeding, Stroke, intermountain medical center, intermountain healthcare, Heart Rhythm Society

Study: Long-Term Use of Aspirin Doesn’t Lower Risk of Stroke in Some Patients with Atrial Fibrillation

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A new study by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City found that using long-term aspirin therapy to prevent strokes among patients who are considered to be at low risk for stroke may not be effective as previously thought.

Medicine

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Brain Cancer, Gliobastoma, PTEN

Ludwig Researchers Identify Counterintuitive Approach to Treating a Brain Cancer

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The loss of the tumor suppressor gene PTEN has been linked to tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM). Now, Ludwig researchers have shown that one way to override the growth-promoting effects of PTEN deletion is, surprisingly, to inhibit a separate tumor suppressor gene.

Medicine

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Simulation education, Simman, Brain Death, apnea test

Mannequin, Trained Actors Help Physicians Diagnose and Communicate Brain Death

A Loyola Medicine study has found that two simulation techniques dramatically improved physicians' brain death diagnostic and communications skills. The techniques employ SimMan® 3G, a high-tech patient simulator (mannequin) and actors who simulate family members having a brain-death discussions.







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