UC Irvine College of Medicine researchers have found that high blood pressure can be induced -- and brought back to normal -- by changing levels of highly reactive oxygen molecules called free radicals and nitric oxide, which currently is being studied for its role in cardiovascular disease and other functions in the body (Hypertension, 8-00).
New research at the University of North Carolina at Chapel Hill shows that men infected with HIV will more rapidly develop AIDS if they use strategies of denial to cope with the disease threat.
One of the quiet miseries of long-term diabetes is a condition called gastroparesis --a failure of the stomach to empty after a meal because the valve-like pyloric muscle won't relax. Gastroparesis affects nearly 75 percent of people who've had diabetes more than five years, causing bloating, pain, loss of appetite and, on occasion, vomiting and dehydration.
Researchers have developed a cheaper, more environmentally friendly bioprocess for manufacturing derivatives of cephalosporins-antibiotics commonly used to treat pneumonia, skin infections, and meningitis. This is the first work that allows the production of cephalosporins without the use of complex chemical syntheses.
Scientists have come up with a promising approach that may allow an earlier diagnosis of Alzheimer's disease. At the moment, confirmation of the disease can be done only after a person has died. These experiments support development of earlier therapeutic intervention.
Doctors at the University of Illinois at Chicago Medical Center used a endoscope procedure to remove an early-stage esophageal cancer, sparing the patient from major surgery. The two-hour procedure was a first for Chicago and is performed at only a few centers worldwide.
Researchers at Purdue University are developing new electronic sensors that should be able to detect the deadly pathogen Listeria monocytogenes in food processing lines.
The Bill and Melinda Gates Foundation will issue a nearly $45 million grant to Harvard Medical School for the creation of a partnership that will develop a replicable model for controlling multidrug-resistant tuberculosis.
A team of head and neck surgeons from the University of Michigan have completed a study that reveals most of the head and neck squamous cell carcinoma tumor cell lines with p53 mutations are sensitive to cisplatin whereas those with wild-type p53 tend to be more resistant.
The results of a randomized trial conducted by a team of Italian head and neck surgeons indicate that a combined chemo-surgical approach for the treatment of oral cavity cancer does not offer an increased chance of survival, when compared to surgery alone in advanced oral cavity cancer.
Premalignant lesions precede a majority of the oral cancers in India. Most of the cancers seen are stage III/IV. This distinct premalignant condition oral cancer offers a reliable model to study the multi-step theory of how p53 tumor suppressor gene plays an important role in normal cellular growth and differentiation in oral carcinogenesis.
A team of head and neck surgeons from Madrid proved that a Near-Total Laryngectomy, allowing preservation of part of the larynx and tumor control, results in patients' retaining part or most of their voice.
Delaying diagnosis of some head and neck cancers has not proven to have an impact on the extent of disease when found. If these findings are confirmed and found to extend to other cancer types, as is likely, then it will have important ramification on future health strategy for cancer in general and specifically head and neck.
Of the treatment options for tonsillar cancer, irradiation offers a similar chance of cure and a lower risk of complications when compared to surgery, finds a University of Florida College of Medicine study.
Elderly patients who have thyroid cancer and those electing to have a partial-thyroidectomy are at higher risk for cancer recurrence, according to researchers at the M.D. Anderson Cancer Center in Houston.
When recurrent or new tumors occur in previously irradiated patients and they are not resectable, treatment options are limited. A new study examines how effective re-irradiation is in providing local control and cure.
PPARgamma may be important in carcinogenesis. Solid tumors such as colon, prostate, and breast cancers express PPARgamma. A new study suggests that ligands may have a role in preventing or treating head and neck cancer.
The perception of the nasopharynx as a surgical no man's land has changed. A team of head and neck surgeons from Taiwan has demonstrated that a nasopharyngectomy, or salvage surgery, is an effective control of Nasopharyngeal carcinoma recurrence when radiation therapy fails.
A new study identifies several clinical and pathologic criteria associated with distant metastasis. This is the first study with lengthy follow-up data and large patient population to correlate these prognostic factors to rates of distant metastasis in head and neck squamous cell carcinoma.
A team of French cancer researchers has determined that younger patients with head and neck squamous cell carcinoma will have similar outcomes to older patients with the same disease and this occurs despite the consensus that younger patients can tolerate more aggressive treatments for the cancer.
That some patients with advanced head and neck cancer would benefit from additional systemic treatment designed to eradicate clinically unidentified tumors that spread to distant parts of the body has been determined by a team of head and neck surgeons from The University of Tennessee-Memphis.
A study from the M.D. Anderson Cancer Center provides objective data that Botulinum toxin provides a simpler, quite effective, standard of care for a select group of cancer patients who might not have been able to successfully speak following laryngectomy.
A new study suggests that patients with head and neck cancer have a greater propensity for alcohol abuse and depression than patients with cancer in other parts of the body. Its conclusions recommend new strategies of treatment for head and neck surgeons.
A UAB research program is helping women make wise decisions on issues surrounding menopause, including whether to have a hysterectomy or begin hormone replacement therapy.
Harvard Medical School (HMS) and Aetna U.S. Healthcare today announced that they have entered into an agreement for HMS to become the flagship medical content partner of InteliHealth (www.intelihealth.com), Aetna U.S. Healthcare's online health information subsidiary.
When it comes to identifying victims in a mass disaster like the Concorde jet crash, "the name of the game is organization," says forensic dental expert Richard Weems, D.M.D.
This month's medical tip sheet from Cedars-Sinai includes: 1) Implantable cardioverter-defibrillator; 2) Laparoscopic Nephrectomy; 3) Javits Award; 4) Fully Endoscopic Pituitary Tumor Removal; 5) Directed Donation Liver Transplant; 6) Cedars-Sinai Ranked Best Among Southern California Heart Hospitals; 7) Bioartificial Liver
New research by a team of researchers from the University of Michigan School of Nursing confirms what health-care professionals suspected about depression: It inhibits short-term memory and directed attention, or concentration.
Having access to a doctor appears to be the single most important factor in determining whether an individual will catch an infection from another infected person who is in close proximity, according to a new study of how disease is transmitted in Cambodia.
When an infant chokes and cannot breathe, immediate first aid is called for, says UAB emergency medicine physician Thomas Terndrup, M.D.
Clinical laboratories will play a vital role in the initial detection of the causative agent and the subsequent diagnosis and treatment of victims should a chemical or biological terrorist event occur.
The human brain is wired with natural checks and balances that control negative emotions but breakdowns in this regulatory system appear to dramatically heighten risk of impulsive violent behavior, according to a University of Wisconsin-Madison study (Science, 7-28-00).
The American Academy of Physician Assistants has released its latest information on PA prescribing which projects PAs recommended or prescribed 196 million pharmaceutical products in 1999 and were responsible for 154 million patient visits.
The last decade has seen a remarkable growth in the use of tumor markers in the U.S., particularly in the management of prostate, breast, and bladder cancers. This development will be discussed at the 52nd Annual Meeting of the American Association for Clinical Chemistry.
An experimental drug, nesiritide, provides new hope for the more than one million patients hospitalized in the U.S. each year with acute congestive heart failure, according to an article in NEJM.
Are cell phones hazardous? Research done so far in both animals and humans has not supported a link to brain cancer, according to the August issue of IEEE Spectrum.
Edward J. Benz, Jr., an internationally recognized hematologist, has been named the next president of the Dana-Farber Cancer Institute. Benz is currently chair of the Department of Medicine at Johns Hopkins University School of Medicine.
Many more patients with chronic pancreatitis can safely turn to a minimally invasive operation for long-term pain relief, according to a study by Johns Hopkins physicians. Endoscopic therapy is an effective alternative to more invasive surgery or drugs (Gastrointestinal Endoscopy, 7-00).
New research shows that irregular or difficult toddler temperament, parental insecurity and parental pursuit of thinness contribute to food refusal and picky eating in toddlers, and are related to infantile anorexia (Journal of the American Academy of Child & Adolescent Psychiatry, 6-00).
Combination of biochemical markers and ultrasonography may significantly reduce the need for amniocentesis, an invasive procedure used to detect Down Syndrome in fetuses.
A national expert will discuss the neonate and the role clinical laboratory testing plays in monitoring the survival and charting the progress of these tiny survivors.
A new computerized method for detecting prostate cancer may lead to earlier detection and eliminate unnecessary biopsites; Findings at 52nd Annual AACC Meeting
Approximately 800,000--or 1 in 5--pregnant women exhibit signs and symptoms of pre-term labor. A laboratory test that screens for fetal fibronectin (fFN) can help physicians more accurately identify pregnant women who are at high risk for pre-term labor and delivery.
Why do some patients respond to some drugs and not to others? Which patients will have minimal or even no toxic effects from a given drug? Why do some individuals require higher or lower doses for optimum response to medication? The answer lies in our genes, says Roland Valdes Jr., Ph.D., President of the National Academy of Clinical Biochemistry.
Advances in the diagnosis and treatment of infertility in the last five years have dramatically changed the outlook for many couples who previously believed they could never have biological children of their own. New procedures have made the diagnosis and treatment of male infertility less invasive and more successful in recent years. High-tech not always the answer for male infertility.
What would the arts and our world be like if Vincent van Gogh had not suffered from manic depression or if President Roosevelt had not been weakened by hypertensive cardiac failure and cachexia during the Yalta Conference, or if Beethoven had not lost his hearing early in life?
The understanding of how the HIV virus replicates in an affected person has led to improved therapeutic approaches, but a cure is still not imminent. An overview of the pathogenesis of HIV and the implications for therapy will be discussed at the 52nd Annual Meeting of the American Association for Clinical Chemistry.
New technologies for diagnosis; monitoring alcohol abstinence; new marker that reflects alcohol consumption signals major new trend.
Scientists reported in July 20, 2000 issue of Human Gene Therapy a new technology that could affect potential safety issues associated with human clinical trials of intravenously administered adenovirus-based drugs, as well as the commercial viability of human gene therapy.
Researchers at Cedars-Sinai Medical Center assisted in developing the computer programs that make sophisticated decisions in a new type of implantable cardioverter-defibrillator that for the first time treats rhythm problems originating in the upper chambers of the heart, as well as those in the lower chambers.
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