Feature Channels: Neuro

• share
• favorite_border

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders. This discovery may pave the way for the development of improved medications targeting the same pathway. Their findings, detailed in the January 2 online issue of Nature Communications https://doi.org/10.1038/s41467-023-44601-4, show that a brain protein known as the TAAR1 receptor, a drug target known to regulate dopamine signaling in key reward pathways in the brain, differs significantly in humans compared to the preclinical rodent models on which drugs are typically tested. The study suggests considering species-specific differences in drug-receptor interactions and further investigation into ways asenapine affects the body, as steps toward potential therapeutic improvements.

• share
• favorite_border

Researchers in the UNC School of Medicine’s Department of Psychiatry have found that enlarged perivascular spaces in the brains of babies, caused by an accumulation of excess cerebrospinal fluid, have a 2.2 times greater chance of developing autism later in life.

• share
• favorite_border

Announcement of contents of the January 2024 issue of Neurosurgical Focus

• share
• favorite_border

Announcement of contents of the January 2024 issue of Neurosurgical Focus: Video

• share
• favorite_border

The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM), is excited to share that the Abstract Submission Application opens January 1, 2024, for the upcoming AANEM Annual Meeting.

• share
• favorite_border

Scientists at the Johns Hopkins University School of Medicine and the National Institutes of Health have identified a protein in the visual system of mice that appears to be key for stabilizing the body’s circadian rhythms by buffering the brain’s response to light.

• share
• favorite_border

A research team led by Dr. Kim, Hyungmin of the Bionics Research Center at the Korea Institute of Science and Technology (KIST) has developed a real-time acoustic simulation technology based on generative AI to predict and correct the distortion of the ultrasound focus position caused by the skull in real-time during focused ultrasound therapy.

• share
• favorite_border

Developed by University of Wisconsin–Madison engineers, the new material — a vertically aligned carbon nanotube foam—can dissipate an enormous amount of rotational kinetic energy from an impact.

• share
• favorite_border

Rochester, Minn. (Dec. 22, 2023)- The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) is excited to host the neuromuscular (NM) fellowship match again in 2024.

• share
• favorite_border

Rochester, Minn. (Dec. 22, 2023) - The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) and American Neuromuscular Foundation (ANF) are excited to announce Dianna Quan, MD, as the 2024 association and foundation president.

• share
• favorite_border

Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s Mary Sedarous, M.D., medical director of the ALS Center, was honored at ALS United Mid-Atlantic’s 2023 Annual Celebration with the organization’s Flame of Hope Award, recognizing research and innovation.

• share
• favorite_border

Rochester, Minn. (Dec. 21, 2023)- The American Neuromuscular Foundation (ANF), is excited to announce that Tyler Nelson, PhD, has been selected as one of the 2023 Development Grant recipients for his research project, “Analysis of a Novel Primary Periodic Paralysis SCN4A Mutation With Pain as a Major Phenotype.”

• share
• favorite_border

Rochester, Minn. (Dec. 21, 2023)- The American Neuromuscular Foundation (ANF), is excited to announce that Erika Williams, MD, PhD, has been selected as one of the 2023 Development Grant recipients for her research project, “Genetically Decoding Human Afferent and Efferent Autonomic Ganglia.”

• share
• favorite_border

Rochester, Minn. (Dec. 21, 2023)- The American Neuromuscular Foundation (ANF), is excited to announce that Mai Yamakawa, MD, has been selected as one of the 2023 Development Grant recipients for her research project, “Causal Genetic Variation and Transcriptomic Signatures of the Peripheral Immune System in the Central Nervous System Pathology of ALS That Are Conserved or Divergent Among ALS Patients and the Animal Models.”

• share
• favorite_border

Scientists at St. Jude Children’s Research Hospital used cryo-electron microscopy to characterize the interaction of two proteins implicated in Parkinson’s disease.

• share
• favorite_border

Mayo Clinic researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease.

• share
• favorite_border

A new report by a UCLA neurologist and collaborators draws upon patient voices and lived experiences to identify the common pitfalls of Parkinson’s diagnoses and create a guidebook for how medical providers – from seasoned specialists to rural community physicians – can avoid them.

• share
• favorite_border

Patient-specific mutation-engineered mouse reveals how sensory neurons may trigger some allergy conditions but block others, suggesting more precise design of JAK inhibitors is necessary.

• share
• favorite_border

Signs of injury to the brain’s white matter called white matter hyperintensities, as seen on brain scans, may be tied more strongly to vascular risk factors, brain shrinkage, and other markers of dementia in former tackle football players than in those who did not play football, according to a study published in the December 20, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

• share
• favorite_border

With the rise in machine learning applications and artificial intelligence, it's no wonder that more and more scientists and researchers are turning to supercomputers. Supercomputers are commonly used for making predictions with advanced modeling and simulations. This can be applied to climate research, weather forecasting, genomic sequencing, space exploration, aviation engineering and more.

• share
• favorite_border

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer’s disease.

• share
• favorite_border

Acute spinal cord injury (SCI) patients lose body weight and muscle mass, despite being on a high-calorie diet while in the intensive care unit. Their muscle wasting is substantial and extends beyond what can explained by inactivity or denervation (loss of nerve supply) alone.

• share
• favorite_border

University of Virginia Alzheimer’s researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

• share
• favorite_border

Technology developed at the University of Wisconsin–Madison to grow “rosettes” of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.It’s the latest discovery using RosetteArray technology, a screening tool that uses stem cells to generate embryonic forebrain or spinal cord tissue structures called neural rosettes.

• share
• favorite_border

• share
• favorite_border

AANS and CNS launch search to replace her as head of neurosurgery’s Washington Office.

• share
• favorite_border

A “chaperone” molecule that slows the formation of certain proteins reversed disease signs, including memory impairment, in a mouse model of Alzheimer’s disease, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

• share
• favorite_border

Nearly 30% of caregivers of severe stroke patients experience high levels of anxiety, depression or post-traumatic stress during the first year after the patient leaves the hospital.

• share
• favorite_border

Artificial intelligence developed to model written language can be utilized to predict events in people's lives.

• share
• favorite_border

A so-called pathological protein long associated with Parkinson’s disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition.

• share
• favorite_border

While the holiday season can bring joy to people of all ages, it also leaves many feeling depressed and lonely.

• share
• favorite_border

Northwestern University researchers have developed the first physics-based metric to predict whether or not a person might someday suffer an aortic aneurysm, a deadly condition that often causes no symptoms until it ruptures.

• share
• favorite_border

Neurologists often diagnose Alzheimer’s disease after evaluating patients during lengthy, in-person office visits.

• share
• favorite_border

It's a consistent tingling feeling and is typically treated with surgery. Now, there may be better options

• share
• favorite_border

Biomedical engineering researchers at Arizona State University are using artificial intelligence to accelerate medical advances.

• share
• favorite_border

Moffitt Cancer Center researchers are working to better understand the molecular mechanisms that promote the development and progression of breast cancer brain metastasis to help improve diagnostics and treatments. In a new study published in the December issue of Cell Reports, they report on identifying a cell signaling pathway that controls breast cancer brain metastasis.

• share
• favorite_border

Breastfeeding, even partially alongside formula feeding, changes the chemical makeup—or metabolome—of an infant’s gut in ways that positively influence brain development and may boost test scores years later, suggests new CU Boulder research.

• share
• favorite_border

About 40 percent of people over age 65 suffer some form of age-related memory loss, which puts them at higher risk for developing dementia and Alzheimer’s disease.

• share
• favorite_border

UC Davis researchers are recruiting infants ages 6-12 months for a new national telehealth study aimed at understanding which developmental delays could indicate autism or other conditions.