The U.S. Food and Drug Administration (FDA) recently granted approval to Lecanemab, the first Alzheimer’s disease treatment to win approval since the largely failed rollout of Aduhelm two years ago.
Maintaining a healthy weight during the golden years is a priority for many older adults. While previous research has shown that cutting calories can lower disease risk factors, it's unclear whether it can have a long-term positive impact on disease and disability. With a $2.1 million grant from the National Institutes of Health, researchers at Wake Forest University School of Medicine will evaluate the potential benefits of diet interventions such as time-restricted eating and caloric restriction.
Being affected by several cardiometabolic diseases such as diabetes, heart disease and stroke, is linked to a greatly increased risk of dementia and Alzheimer’s disease.
In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.
From a cranky-faced fetus scowling at her mother’s healthy lunch choice to an octogenarian still benefiting from long-ago musical lessons, the most impactful psychological science research published in 2022 reveals that new understandings of human behavior—studied across the lifespan and from within a remarkable diversity of topics and scientific subdisciplines—continue to resonate with wide audiences.
Researchers have uncovered sphingolipid accumulation as a new mechanism that affects ageing. Ceramides, the best-known class of sphingolipids, accumulate in aged muscle, impairing its function while also affecting functional capacity in older adults.
In a study using data from nearly 1,200 older adults, Johns Hopkins Medicine researchers have added to a growing body of evidence that loss of the sense of smell is a predictive marker for an increased risk of frailty as people age.
Early retirement can accelerate cognitive decline among the elderly, according to research conducted by faculty at Binghamton University, State University of New York.
UC San Diego School of Medicine study shows cannabis-related emergency department visits among older adults are on the rise with high risk for adverse effects of cannabis use for ages 65 and older.
Findings from a UC Davis Comprehensive Cancer Center study prompt researchers to question current cervical cancer screening guidelines for older women.
Two separate eye diseases may contribute to age-related macular degeneration (AMD), a leading cause of blindness in the United States, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.
The U.S. Food and Drug Administration is poised to make a decision on another new Alzheimer’s disease treatment this week, and experts from the Jona Goldrich Center for Alzheimer’s and Memory Disorders at Cedars-Sinai are available to explain how the drug works and which patients could benefit from the medication.
Researchers investigated the role of one cellular mechanism in improving physical fitness by exercise training and identified one anti-aging intervention that delayed the declines that occur with aging in the model organism.
Recent evidence has emerged to suggest that age-related macular degeneration (AMD) is a clinical risk factor for increased risk for infection and mortality.
Bar Harbor, ME/Farmington, CT—Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells.
Sedentary behavior, a large waist circumference, and advanced age: These factors are clearly associated with inferior physical fitness among people aged 50 to 64.
The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.
Looking for answers about how the brain works amid age-related hearing loss, Johns Hopkins Medicine researchers say they found that old mice were less capable than young mice of “turning off” certain actively firing brain cells in the midst of ambient noise.
Emergency preparedness in nursing homes should be commensurate with local environmental risks to ensure residents’ safety, but new research in the Journal of the American Geriatrics Society found that nursing homes in California that face a greater risk of wildfire exposure have poorer compliance with Medicare’s emergency preparedness standards.
Older heart failure patients who feel that they have lost their social role amongst friends and family are more likely to suffer poor clinical outcomes.
A first-in-kind program that trains trusted older adult community health workers to fit and deliver low-cost hearing technology to peers with hearing loss significantly improved communication function among participants, according to the results of a randomized clinical trial led by Johns Hopkins Medicine researchers.
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A recent study from the University of Eastern Finland shows that previous traumatic brain injury may potentially affect the risk of frontotemporal dementia.
A recent study by researchers from the NUS Yong Loo Lin School of Medicine and the Memory, Ageing and Cognition Centre under the National University Health System revealed that low levels of ergothioneine in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly.
Japan’s population is rapidly aging. As a result, new challenges have emerged as an increased number of elderly people, many of whom live in isolated parts of the country, need medical and nursing care despite inadequate medical resources.
Researchers at UC San Diego provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer’s, making it very difficult to identify in living patients.
Alzheimer’s disease (AD) is the fifth leading cause of death in adults over 65 years old. While many potential treatments for the neurodegenerative disease focus on developing drugs to target key culprits, a relatively new approach aims to more directly treat the brain.
What are the keys to “successful” or optimal aging? A new study followed more than 7000 middle aged and older Canadians for approximately three years to identify the factors linked to well-being as we age.
For decades, doctors and scientists have known that exercise is important for older adults — it can lower risk for cardiac issues, strengthen bones, improve mood and have other benefits. Likewise, mindfulness training reduces stress, and stress can be bad for the brain, so many have thought that exercise and/or mindfulness training might improve brain function.
New research suggests that former professional football players may face accelerated aging, despite past research showing they have life spans similar or longer than the general population
In the new study, retired football players reported shorter health spans — defined as years free of disease – than men in the general population
Two age-related diseases — arthritis and dementia — were found more commonly among former football players, compared with men of the same age in the general population
Additionally, hypertension and diabetes were more common among younger former players, those ages 25 to 29, compared with same-age men from the general population.
The results warrant further study to define the biochemical, cellular, and physiologic mechanisms behind premature aging in former football players
UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.
Their older parents need care. Their kids are still under 18. And they probably have a job, too. They’re the “sandwich generation” – a longtime nickname for the mostly female, mostly middle-aged group of Americans who serve as caregivers for both older and younger family members at once. A new study estimates there are at least 2.5 million of them, while giving a detailed view into who they are, and which older adults rely on them.
Researchers at Tufts University have completed the first study examining levels of vitamin D in brain tissue, specifically in adults who suffered from varying rates of cognitive decline. They found that members of this group with higher levels of vitamin D in their brains had better cognitive function.
Businesses are more often turning to older workers to fill employment gaps and a new University of Iowa study finds countries that spend more on health care don’t see a significant difference in sick days taken by younger and older workers.
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.
With flu cases on the rise, geriatric specialists at UT Southwestern Medical Center say vaccinations are particularly important this year for people 65 and older who are more at risk from complications than other age groups.