The NIH has awarded the UNC HIV Cure Center and Cell Microsystems a Small Business Innovation and Research contract to develop an automated platform to quantify the latent HIV reservoir, a key step in finding a cure for the virus.
Wistar scientists have applied their synthetic DNA technology to engineer a novel eCD4-Ig anti-HIV agent and to enhance its potency in vivo, providing a new simple strategy for constructing complex therapeutics for infectious agents as well as for diverse implications in therapeutic delivery.
A relatively simple effort to provide counseling and connect injection-drug users with resources could prove powerful against the spread of HIV in a notoriously hard-to-reach population, new research suggests.
Researchers at the University of North Carolina at Chapel Hill have found that crowdsourced campaigns can motivated men at-risk of HIV infection in China to get tested.
Using the BioSANS instrument at DOE’s ORNL, a team of researchers from the University of Pennsylvania’s Perelman School of Medicine explores future HIV treatments. Specifically, the researchers hope to better understand how HIV evolves to combat ALLINIs, a new class of HIV-fighting drug. With the information they’ve gathered at ORNL, the researchers hope to pave the way for more effective HIV treatments in the future.
In a pair of new modeling studies, researchers at University of California San Diego School of Medicine, with international colleagues, examined how policy reform in terms of drug decriminalization (in Mexico) and access to drug treatment (in Russia) might affect two regions hard hit by the HIV pandemic: Tijuana, Mexico and the Russian cities of Omsk and Ekaterinburg.
An international research group, which included an ISU scientist, has proven that three proteins that can help prevent the spread of HIV can be expressed in transgenic rice plants. Using plants as a production platform could provide a cost-effective means of producing prophylactics, particularly in the developing world.
Using genetic sequencing to understand the evolutionary relationships among pathogens, an international team of researchers—including several from the Center for Drug Use and HIV/HCV Research (CDUHR) at New York University—has developed a new method to determine how effective interventions are against the spread of infectious diseases like HIV.
Johns Hopkins scientists report they have identified two potential new drug targets for the treatment of HIV. The finding is from results of a small, preliminary study of 19 people infected with both HIV—the virus that causes AIDS—and the hepatitis C virus. The study revealed that two genes—CMPK2 and BCLG, are selectively activated in the presence of type 1 interferon, a drug once used as the first line of treatment against hepatitis C.
In a recently published study in the journal Nature Microbiology, researchers at Los Alamos National Laboratory show that computer simulations can accurately predict the transmission of HIV across populations, which could aid in preventing the disease.
Wolters Kluwer Health announced today it will begin publishing The Journal of the Association of Nurses in AIDS Care from the Association of Nurses in AIDS Care (ANAC). Under the new partnership, Wolters Kluwer will publish the clinical and scientific journal in its Lippincott Portfolio beginning January 2019.
Ortho Clinical Diagnostics, a global leader of in vitro diagnostics, announced that its VITROS Immunodiagnostic Products HIV Combo Reagent Pack and Calibrator (VITROS® HIV Combo test) received approval from the U.S. Food and Drug Administration for use on Ortho’s VITROS 3600 Immunodiagnostic System
Finalists for the 2018 P3 Impact Award were announced by the Office of Global Partnerships at the U.S. Department of State, the University of Virginia Darden School of Business Institute for Business in Society and Concordia. The award recognizes exemplary public-private partnerships (P3s) that provide solutions to pressing issues in areas such as: economic development, housing, health and sanitation, and workforce.
Los Alamos scientist Bette Korber was recently honored with the 2018 Richard P. Feynman Innovation Prize for her ground-breaking HIV vaccine designs. Korber was recognized at a ceremony that celebrates the “Next Big Idea” – scientific breakthroughs that achieved exceptional innovation.
A group of scientists at Texas Biomedical Research Institute have zeroed in on a new defense against HIV-1, the virus that causes AIDS. Led by Ruth Ruprecht, M.D., Ph.D., the team used an animal model to show for the first time that an antibody called Immunoglobulin M (IgM) was effective in preventing infection after mucosal AIDS virus exposure.
After 42 years as the oldest and largest, independent non-profit organization in the United States solely focused on infectious disease research, The Center for Infectious Disease Research (CIDR) will join Seattle Children’s Research Institute to create a world-class team of researchers working to find viable solutions to infectious diseases that can pose risks to our communities, and disproportionately impact children and those in poverty.
The National Institutes of Health has awarded a five-year, $42 million grant to the Tulane National Primate Research Center to continue its mission to fight diseases and improve human health through biomedical research.
In a new study, published July 6 in The Lancet, a team of researchers led by Beth Israel Deaconess Medical Center's Dan H. Barouch, MD, PhD, in collaboration with Janssen Vaccines & Prevention and other partners, evaluated a series of preventative HIV vaccine regimens in uninfected human volunteers in five countries. In a similarly designed study, Barouch and colleagues tested the same vaccine for its ability to protect rhesus monkeys challenged with an HIV-like virus from infection. The findings showed the vaccines induced robust and comparable immune responses in humans and monkeys and protected monkeys against acquisition of infection.
A gamified HIV prevention program reduced sexually transmitted infections by 40 percent in America's most at-risk population - men, ages 18-29, who have sex with men.
Gay and bisexual men are disproportionately affected by HIV/AIDS illness and death in the U.S., accounting for 70 percent of new HIV infections. Furthermore, among men who have sex with men (MSM), black MSM are disproportionately at risk of HIV infection. Alcohol consumption may play a role in HIV transmission because it can lead individuals to have sex without using a condom. This study examined the links between condom use and drinking, before and during sex, and alcohol-use problems.
An experimental model of HIV infection in mice, developed by Mount Sinai researchers, has shown that HIV causes learning and memory dysfunction, a cognitive disease that is now observed in about half of HIV infected people that worsens with age, and is currently incurable.
Jeremy Boal, MD, President of Mount Sinai Downtown and Executive Vice President and Chief Clinical Officer of the Mount Sinai Health System, was presented the 2018 Esperanza Award by the Latino Commission on AIDS.
Two strategies that research indicates would help alleviate America’s opioid crisis lack widespread public support, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.
A new study by University of North Carolina School of Medicine researchers has found that T cells, a type of white blood cell and an essential part of the immune system, are sufficient by themselves to establish and maintain an HIV infection in the brain.
Rutgers Global Health Institute’s director discusses how rejecting scientific facts can undermine progress in public health – and how the medical profession can further public understanding of science
This month's tip sheet from Fred Hutch includes information about cancer care delivery and costs, partnering with Microsoft, understanding/changing cancer's genetics and a Mt. Everest climb for cancer research fundraising. To pursue any of these story ideas, please contact the individual listed for each.
Fred Hutchinson Cancer Research Center’s latest findings will be featured at the annual meeting of the American Society of Clinical Oncology, “Delivering Discoveries: Expanding the Reach of Precision Medicine,” to be held June 1–5 in Chicago. Here are several highlights:
FINDINGS UCLA-led research suggests that receiving support from friends and acquaintances can help prevent black men who have sex with men from becoming infected with HIV. BACKGROUND Black men who have sex with men have disproportionately high rates of HIV infection. While social connections are known to influence the behaviors that influence people’s risk for HIV, little is known about whether they affect the risk for becoming infected with HIV.
TIME named University of Pennsylvania cancer and HIV gene therapy pioneer Carl June, MD, to the 2018 TIME 100, its annual list of the 100 most influential people in the world.
An international team focused on HIV cure research spearheaded by The Wistar Institute in collaboration with the University of Pennsylvania and Vall d’Hebron Research Institute (VHIR) in Barcelona, Spain, established that the CD32 molecule is not a preferential biomarker to identify HIV silent reservoirs within the immune system of patients undergoing antiretroviral therapy (ART), as proposed by a recent landmark study.
Researchers at the University of Minnesota and The Dow Chemical Company have joined forces to tackle one of the biggest challenges in health care—how to get life-saving medicines to work faster and better with fewer side effects.
The National Institute of Allergy and Infectious Diseases has awarded a five-year, $15 million grant to the San Diego Center for AIDS Research (CFAR) at UC San Diego, renewing support that extends back to an original establishing grant in 1994—the height of the AIDS epidemic.
Taking the road home to Baltimore rewards an HIV researcher and a community-minded caregiver. The city provides fertile ground for their contributions.
Fred Hutchinson Cancer Research Center’s latest findings will be featured in about 50 presentations at the annual meeting of the American Association for Cancer Research, “Driving Innovative Cancer Science to Patient Care,” to be held April 14-18 in Chicago. Here are several highlights:
Researchers at Université de Montréal and the research centres of the CHUM and CHU Sainte-Justine are banding together to conquer this rare orphan pediatric disease. They have recently proven what scientists had already suspected: the disease is autoimmune, which means that it attacks patients using their own immune system.