NK cell content does not seem to influence engraftment in ex vivo T cell depleted haploidentical stem cell tra … usefulness of NK cellderived IFNg inhibition to favor engraftment in allogeneic hematopoietic stem cell transplantation (HSCT) …
… Post-TAVR stroke causes acute and long-term morbidity and mortality. The stroke rate 30 days after TAVR was reported as 3.4% in low-risk … TAVR may reduce the incidence of ischemic stroke and in-hospital mortality.However, the effectiveness of …
… In addition, MSCs derived from different donors and tissues lead to individual heterogeneity, which complicates the progress of consistent and standardized stem cell production. Therefore, it is necessary to screen qualified MSCs to avoid uncertain effects. …
The time of day that people with diabetes eat certain foods may be just as important to their well-being as portion size and calories, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism.
Cognitive decline is the biggest factor in determining how long patients with Alzheimer’s disease will live after being diagnosed, according to a new study from researchers at UT Southwestern. The findings, published in the Journal of Alzheimer’s Disease, are a first step that could help health care providers provide reliable prediction and planning assistance for patients with Alzheimer’s disease and their families.
Mass Eye and Ear research shows the viral vector Anc80L65 efficiently transferred genetic cargo into the inner ear of nonhuman primates via a specialized surgical procedure, paving the way for a method that can be brought to clinical trials for hearing loss and vestibular disorder treatments.
For the first time, Australian researchers have reverse engineered the visual systems of hoverflies to detect drones’ acoustic signatures from almost four kilometres away. The finding could help combat the growing use of IED-carrying drones, including those used in Ukraine.
Federal researchers have identified specific inherited, or “germline,” gene mutations associated with prostate cancer development specifically among African American men. This discovery could impact cancer screening and prevention and also lead to more effective, targeted treatments and better outcomes for individuals who have these mutations. These findings were published in Nature Communications on March 15, 2022.
When used as biocatalysts, enzymes accelerate many chemical reactions. At Karlsruhe Institute of Technology (KIT), researchers have now embedded enzymes in metal-organic cages (MOFs). For the first time, they then demonstrated that stabilization by these frameworks is sufficient for use of the enzymes in a continuous reactor. Moreover, the enzymes embedded in the MOFs cannot only be used in aqueous, but also in organic solvents. The researchers report in the journal Angewandte Chemie (DOI: 10.1002/anie.202117144).
A new target in the brain which underpins the eliciting of anxiety and fear behaviours such as ‘freezing’ has been identified by neuroscientists. The University of Bristol researchers say the discovery of a key pathway in the brain, published in the journal eLife, offers a potential new drug target for treating anxiety and psychological disorders, which affect an estimated 264-million people worldwide.
Financial incentives and other nudges have been used to help increase vaccination rates across the nation, but new research from the University of California San Diego’s Rady School of Management reveals that compensations need to be large—at least $100—to reduce vaccine hesitancy.
Cold spells, wildfires, hurricanes and other events are happening with increasing intensity. As the share of weather-dependent energy sources grows, electricity markets and power systems have the opportunity to improve short- and long-term plans.
The study expands the fundamental understanding of cartilage mechanics and demonstrates a valuable new research tool.
Kelly Dunn recently became board certified by the Academy of Nutrition and Dietetics in Oncology Nutrition.
A new study estimates that over the next 30 years, 1.4 million street trees will be killed by invasive insects, costing over 900 million dollars to replace.
A single-celled marine microbe capable of photosynthesis and hunting and eating prey may be a secret weapon in the battle against climate change.
Notre Dame Assistant Professor Adrienne Sabety and a colleague from MIT partnered with the New York City Department of Health and Mental Hygiene to determine how access to primary care would affect both undocumented immigrants’ health and the use of emergency departments for routine care.
A researcher at the University of Maryland School of Medicine, and his colleagues at Harvard University, have shown in rats how several brain regions need to work together to acquire a skill and replicate it flawlessly with each rat adding their own personal flair in the form of a “dance.”
PSI scientists have developed a ground-breaking achromatic lens for X-rays. This allows the X-ray beams to be accurately focused on a single point even if they have different wavelengths.
For the first 2 billion years of Earth’s history, there was barely any oxygen in the air. While some microbes were photosynthesizing by the latter part of this period, oxygen had not yet accumulated at levels that would impact the global biosphere.
From sunflowers to starfish, symmetry appears everywhere in biology. This isn’t just true for body plans – the molecular machines keeping our cells alive are also strikingly symmetric.
One in three new mothers during early COVID-19 screened positive for postpartum depression––nearly triple pre-pandemic levels––and 1 in 5 had major depressive symptoms, say University of Michigan researchers.
When the European Space Agency’s Rosetta spacecraft discovered abundant molecular oxygen bursting from comet 67P/Churyumov-Gerasimenko (67P) in 2015, it puzzled scientists. They had never seen a comet emit oxygen, let alone in such abundance. But most alarming were the deeper implications: that researchers had to account for so much oxygen, which meant reconsidering everything they thought they already knew about the chemistry of the early solar system and how it formed. A new analysis, however, led by planetary scientist Adrienn Luspay-Kuti at the Johns Hopkins Applied Physics Laboratory (APL) in Laurel, Maryland, shows Rosetta’s discovery may not be as strange as scientists first imagined.
Texas A&M AgriLife Research scientists are using artificial intelligence to set a new world record for producing algae as a reliable, economic source for biofuel that can be used as an alternative fuel source for jet aircraft and other transportation needs.
LGBT+ physicists often face harassment and other behaviors that make them leave the profession, according to a new study, which comes as physics as a discipline has attempted to grapple with equity and inclusion issues. The authors found that the two biggest factors that influence a person’s decision to leave physics are the overall climate of the organization they belong to and more specifically observing exclusionary behavior.
Higher lead levels in a mother's blood can increase the chance of her bearing male offspring, according to new research led by Japanese scientists at the Tohoku University Graduate School of Medicine.
People living with neurological or psychiatric conditions may have an increased likelihood of having a second such condition in the future, and their sex influences their risk, according to new research.
In a paper published on Small recently, a collaborated research team led by Prof. WANG Hui from High Magnetic Field Laboratory, Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS) reported the synthesis of hollow cuprous oxide@nitrogen-doped carbon (HCONC) by one-step hydrothermal method as well as their applications in efficient chemodynamic therapy.
To evaluate the safety and early outcomes of autologous bone marrow mononuclear cell (BMMNC) infusion for liver cirrhosis due to biliary atresia (BA) after Kasai operation.
Researchers developed a new computational model to study gene expression trends over time and applied datasets from COVID-19 patients -- they found that early and persistent activation of neutrophils is a hallmark of severe COVID-19 illness.
Keck Medicine of USC study shows that the incidence rate of metastatic prostate cancer rose as much as 43% in men 75 and older and 41% in men 45-74 after routine prostate cancer screenings were no longer recommended
People who kill themselves with a firearm are more likely to talk about suicide a month before ending their lives than ask for help and seek mental health treatment, according to a study by the New Jersey Gun Violence Center at Rutgers University.
Scientists have developed a method for tracking the invasive Asian giant “murder” hornet’s presence and possibly accelerate its removal. The researchers identified the Asian giant hornet queen’s sex pheromone, an achievement that could be used as bait to trap and track the insects.
Researchers have found direct evidence of the existence of anyons, a quasiparticle first predicted in the 1970s. These particles behave in two-dimensional systems in ways very different from their three-dimensional quasiparticle cousins, fermions, and bosons. The results could help to improve the duration of coherence in future quantum computer qubits.
Three physicists at Brookhaven National Laboratory have recently developed a model to explain the formation of supermassive black holes, as well as the nature of another phenomenon: dark matter. In a paper published in Physical Review Letters, they describe a cosmological phase transition that facilitated the formation of supermassive black holes in a dark sector of the universe.
A new research paper says, ‘wave reserves’ are a good way to ensure the conservation of ecologically valuable coastal areas
Two new papers from the University of Chicago Medicine show increasing doses of THC, the main main psychoactive ingredient in cannabis, can increase bodily anxiety in women. Meanwhile, researchers in the lab of Dr. Harriet de Wit also found that when compared to adults, adolescents are more negatively impacted by THC on cognitive tasks.
In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers at Johns Hopkins Medicine and Tottori University in Japan have genetically engineered and characterized what is believed to be the first rat model of Down syndrome.
Exposure to ozone from air pollution has been linked to an increase in depressive symptoms for adolescents over time, even in neighborhoods that meet air quality standards, according to new research published by the American Psychological Association.
Research in the March 2022 issue of JNCCN examined the impact of the COVID-19 pandemic on the number of new cancer cases detected. They found the week-to-week rate of diagnosis was steady before the pandemic, but dropped 34.3% in March of 2020.
The ability to make perceptual and conceptual judgements such as knowing the difference between a picture of an object and the actual 3D object itself has been considered a defining capacity of primates, until now. A study provides the very first behavioral evidence that laboratory mice are capable of higher-order cognitive processes. Findings also provide strong support that the mouse’s hippocampus, like that of humans, is required for this form of nonspatial visual recognition memory and picture-object equivalence.
In a new article published in the March issue of Emerging Infectious Diseases, Moffitt researchers set out to estimate the percentage of Hillsborough County residents who had COVID infection and better understand demographics and behavioral factors associated with infection.
Researchers have developed a new method for training people to be creative, one that shows promise of succeeding far better than current ways of sparking innovation.
The short-term safety and efficacy of stromal vascular fraction (SVF) in treating knee osteoarthritis (KOA) have been extensively studied but the mid-term and long-term prognoses remain unknown.
Acute kidney injury (AKI) causes abrupt deterioration in kidney function that disrupts metabolic, electrolyte and fluid homeostasis. Although the prevalence of AKI is steadily increasing, no definitive treatme...
The balance between osteogenesis and adipogenesis of mesenchymal stem cells (MSCs) is critical to skeletal development and diseases. As a research hotspot, circular RNAs (circRNAs) have expanded our understand...
The liver plays an important role in various metabolic processes, including protein synthesis, lipid and drug metabolisms and detoxifications. Primary culture of hepatocytes is used for the understanding of li...
Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.
Georgia Tech researcher Gabe Kwong and his collaborators have developed a system of synthetic biosensors that will let a patient and doctor quickly learn if a cancer immunotherapy is working, through a non-invasive urinalysis.
Bilal Haider is studying how multiple areas of the brain work together for visual perception. This could help researchers understand if neural activity “traffic jams” underlie all kinds of visual impairments: from running a red light when visual attention is elsewhere, to shedding light on the autism-affected brain.
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