Sights, smells and sounds of everyday life can supply the triggers that take someone with PTSD right back to the scarring scene they’re trying to forget.
BACKGROUNDIschemic stroke is a condition in which an occluded blood vessel interrupts blood flow to the brain and causes irreversible neuronal cell death. Transplantation of regenerative stem cells has been proposed as a novel therapy to restor
BACKGROUNDSpermatogonial stem cells (SSCs) are the origin of male spermatogenesis, which can reconstruct germ cell lineage in mice. However, the application of SSCs for male fertility restoration is hindered due to the unclear mechanisms of pro
BACKGROUNDThere is still no consensus on which concentration of mesenchymal stem cells (MSCs) to use for promoting fracture healing in a rat model of long bone fracture. AIMTo assess the optimal concentration of MSCs for promoting fracture hea
Intervertebral disc degeneration is the main cause of low back pain. In the past 20 years, the injection of mesenchymal stromal cells (MSCs) into the nucleus pulposus of the degenerative disc has become the main approach for the treatment of lo
Using a specialized MRI sensor, MIT researchers have shown that they can detect light deep within tissues such as the brain.
Carnegie Mellon University’s Yongxin (Leon) Zhao and the Chinese University of Hong Kong’s Shih-Chi Chen have a big idea for manufacturing nanodevices.
Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.
Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases. The research team from the National Eye Institute (NEI), part of the National Institutes of Health, printed a combination of cells that form the outer blood-retina barrier—eye tissue that supports the retina's light-sensing photoreceptors. The technique provides a theoretically unlimited supply of patient-derived tissue to study degenerative retinal diseases such as age-related macular degeneration (AMD).
In the new study the authors have examined how conditions under which an amino group attaches to the polymer (temperature and the amount of arginine) affect the resulting qualities of the polycaprolactone film
BioVU, Vanderbilt University Medical Center’s biobank, has reached another milestone — deep-freeze storage of more than 300,000 biological samples.
The incredibly fast spread of COVID-19 throughout the world brought to light a very important fact: we need better methods to diagnose infectious diseases quickly and efficiently.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science led 70 participants from 14 nations in a discussion on the ways in which a gene drive project registry could both contribute to and detract from the fair development, testing and use of gene-drive modified organisms.
The Wistar Institute Biomedical Technician Training (BTT) Program was awarded Workforce Champion of the Year in the 3rd Annual 2022 BioBuzz Awards. The program is a collaborative that includes The Wistar Institute, West Philadelphia Skills Initiative, Iovance Biotherapeutics, PIDC, and others.
This week, the United Nations is meeting in Montreal for the UN Biodiversity Conference. The conference brings together leaders from around the world to discuss how to prevent loss of biodiversity and how to restore habitats that are already hurting.
“Our new Ion Bronchoscopy system is a robotic-assisted minimally invasive biopsy platform. It features an ultra-thin, ultra-maneuverable catheter that allows navigation far into the lung, reaching smaller airways, said Faiz Y. Bhora, MD, FACS, chair of surgery, and chief of thoracic surgery, central region, Hackensack Meridian Health. “This platform’s unprecedented stability enables the precision needed for biopsy compared to manual techniques and the ability to diagnose lung cancer at the earliest stage when it is most treatable."
A new biobattery being developed at Binghamton University, State University of New York could power ingestible cameras in the small intestine.
Since oral cancer occurs in one of the most accessible sites in the body, it can be easily treated if detected promptly. In Journal of Vacuum Science & Technology B, researchers report a breakthrough hand-held biosensor that enables quick and accurate detection of oral cancer. The group's biosensor consists of a sensor strip, similar to a glucose strip, and a circuit board (a hand-held terminal like a glucometer) for detection.
In early 2020, before COVID-19 vaccines and effective treatments were widely available, universal mask wearing was a central strategy for preventing the transmission of COVID-19. But hospitals and other settings with mask mandates faced a challenge.
Using models, researchers at UC San Diego School of Medicine, with colleagues elsewhere, describe using RNA-targeting CRISPR/Cas13d technology to develop a new therapeutic strategy that specifically eliminates toxic RNA that causes Huntington’s Disease.
Restoring natural vision is far in the future. But Neuralink's technology, which will assist the blind to navigate in their world, is on the verge of attainability.
At the session "Can science become a family value?", representatives of scientific and educational organizations, development institutions and businesses discussed how to make science more popular among society.
Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.
Researchers are using a natural material derived from seaweed to promote vascular cell growth, prevent blood clots and improve the performance of synthetic vascular grafts used in heart bypass surgery.
Former FDA official Steven R. Bauer, PhD, will be an available resource to the ever-growing biotechnology innovation ecosystem underway in the Innovation Quarter of Winston-Salem, NC.
Engineers developed a battery-free, pill-shaped ingestible biosensing system that gives scientists the ability to monitor gut metabolites in real time, which wasn’t possible before. The work could lead to a new understanding of intestinal metabolite composition, which significantly impacts human health.
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.
Researchers discover that dual knockout of genes in organoids grown from human tissue generates a model of and potential therapeutic target for gastroesophageal junction cancer
Fang and colleagues provide a comprehensive transcriptomic analysis of the cell types occupying the interface between tendon and bone, the enthesis. They establish a framework for understanding enthesis maturation and identify a potent Gli1-lineage p
Repair of the tendon enthesis (e.g., after a rotator cuff tear) is a clinical challenge. To motivate novel cell-based treatment strategies for enthesis repair, Fang et al. define enthesis cell transcriptomes and differentiation trajectories. A uniqu
The extracellular matrix (ECM) microenvironment is emerging as a player in early human development. Cesare et al. demonstrate that naive hiPSCs exhibit a self-organized ECM-rich microenvironment in vitro, which sustains their identity. They develop
A life well lived inspires others to aspire. Our friend and mentor Susan L. Solomon crammed several lifetimes of exploration into her 71 years. Susan’s early life was filled with music: her mother was a pianist and her father the co-founder of Vang
In this issue of Cell Stem Cell, Porpiglia et al.1 report on alterations in CD47 and THBS1 expression and function in aged muscle stem cells that disrupt their regeneration capacity. Targeting THBS1-CD47 cross-signaling is sufficient to reverse sarc
As the stem cell community mourns the loss of New York Stem Cell Foundation founder Susan Solomon, we also look to celebrate her legacy. In this Voices, members of the 2022 class of NYSCF Roberston Investigators share how NYSCF community support will
Herdy et al. identify an enriched population of senescent neurons in the Alzheimer’s brain, which can be modeled in vitro using induced neurons (iNs) and eliminated with senotherapeutics. Alzheimer’s iNs present molecular and genetic markers of
Pera and colleagues discuss the nature of recurrent genetic and epigenetic variants in hPSC culture, the methods for their detection, and what is known about their effects on cell behavior in vitro or in vivo. They highlight the key challenges faci
Human cortical organoids transplanted into the somatosensory cortex of rats integrate into the host neural circuits, receive inputs from host cells, and can produce behavioral responses. In a publication in Nature, Revah et al.1 highlight the potent
The conference brought together scientists, postgraduate and undergraduate students and representatives of the business community to discuss current research in microbiology and the latest biotechnological developments.
The origin of all biological movements, including walking, swimming, or flying, can be traced back to cellular movements; however, little is known about how cell motility arose in evolution.
Jurata Thin Film, a startup focused on stabilizing vaccines at ambient temperature has raised initial investment funds totaling $4.87 million to develop the technology.
When neurons are damaged by degenerative disease or injury, they have little, if any, ability to heal on their own. Restoring neural networks and their normal function is therefore a significant challenge in the field of tissue engineering. Prof. Orit Shefi and doctoral student Reut Plen from the Kofkin Faculty of Engineering at Bar-Ilan University have developed a novel technique to overcome this challenge using nanotechnology and magnetic manipulations, one of the most innovative approaches to creating neural networks.
Molecular biologist Yu Xin (Will) Wang, Ph.D., has joined Sanford Burnham Prebys as an assistant professor in the Development, Aging, and Regeneration Program to uncover the ways muscle, nerve and immune cells work together to overcome disease.
BACKGROUNDCartilage tissue engineering is a promising strategy for treating cartilage damage. Matrix formation by adipose-derived stem cells (ADSCs), which are one type of seed cell used for cartilage tissue engineering, decreases in the late s
Corneal stem/progenitor cells are typical adult stem/progenitor cells. The human cornea covers the front of the eyeball, which protects the eye from the outside environment while allowing vision. The location and function demand the cornea to m
Nyra Medical, Inc., a medical device company that is developing a novel transcatheter mitral valve repair technology, today announced the closing of a $20 million Series A financing.
The Euglena International Network (EIN) (https://euglenanetwork.org/), founded in 2020, is a global consortium of hundreds of scientists around the world with the collective goal of supporting euglenoid science through collaborative and integrative omics between academics and industry.
The Impella RP Flex is implanted using a minimally invasive catheter-based approach to treat right heart failure
UC San Diego Alpha Stem Cell Clinic awarded $8M to expand clinical trials of novel stem cell therapies. The CIRM award will advance partnerships between academic and industry experts in San Diego to expedite clinical trials for patients with difficult-to-treat diseases.
The transport protein named STARD3 is thought to be responsible for the accumulation of carotenoids in the human retina. It is carotenoids that work in the so-called “yellow spot” (macula lutea) of the retina, protecting it from oxidative stress and age-related degeneration.
Science misinformation about genetically modified crops and foods had a potential global readership of over a quarter of a billion people, according to a new study published by the Alliance for Science, which combats anti-science misinformation on topics like climate, vaccines and GMOs.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
