Feature Channels: Blood

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A St. Jude Children’s Research Hospital study lowered the rate of relapse for patients with acute lymphoblastic leukemia.

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A life-saving course is in development to train high school students around the country how to to deliver the first aid skills for severely injured trauma victims. The education and training course is being created by the Uniformed Services University of the Health Sciences’ National Center for Disaster Medicine and Public Health (NCDMPH) and The American Red Cross (Red Cross). Students who successfully complete the course will receive certificates documenting their first aid training.

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Major burns lead to changes in the gastrointestinal tract bacteria, and these alterations of the gut microbiome are influenced by resuscitation with intravenous (IV) fluids, according to animal studies reported in SHOCK®: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society. The journal is published in the Lippincott portfolio by Wolters Kluwer.

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Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis. The study is sponsored by Juno Therapeutics, Inc. The study’s principal investigator, Mohamad Cherry, MD, medical director of hematology for Atlantic Health System Cancer Care, is a nationally known expert at treating and researching blood-related cancers such as lymphoma, leukemia and myeloma. Dr. Cherry is triple board-certified in internal medicine, hematology and medical oncology

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In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

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A new study of nearly 5 million patients shows the most-popular first-line treatment for hypertension is less effective and causes more side effects than thiazide diuretics.

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Pregnant women with anemia are twice as likely to need blood transfusions after a cesarean delivery, as those without the condition, according to a study being presented at the ANESTHESIOLOGY® 2019 annual meeting.

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The American Society of Anesthesiologists (ASA) today presented Judith Hellman, M.D., with its 2019 Excellence in Research Award in recognition of her outstanding research developments

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Having blood drawn by a courteous health care provider can really take the sting out of those procedures, suggests a study being presented at the ANESTHESIOLOGY® 2019 annual meeting.

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A device designed to improve adherence to outpatient parenteral antimicrobial therapy (OPAT) took top prize at the second IDEA Incubator, a competition showcasing inventions, products and devices to improve patient care for infectious diseases, which takes place during IDWeek.

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African Americans reporting high levels of chronic stress tended to develop high blood pressure, or hypertension, more often than those who reported low stress levels, according to new research published in the Journal of the American Heart Association, the open access journal of the American Heart Association.

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This month, the UCLA Jonsson Cancer Center has launched a pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial that will attack cancer cells by simultaneously recognizing two targets – CD19 and CD20 – that are expressed on B-cell lymphoma and leukemia.

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Now, in experiments in mice as well as isolated human cancer cells, UCLA researchers have discovered a way to eliminate the CML stem cells. Their approach uses an antibody to block a protein that the stem cells rely on to grow. The advance, described in a study published in the Journal of Clinical Investigation, might eventually help treat not only chronic myelogenous leukemia but other cancers as well.

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The effects of a traumatic brain injury (TBI) are pretty clear – problems with memory, headaches, and emotions – but what’s unclear is the underlying pathological causes for those symptoms. According to new research led by researchers at the National Institutes of Neurological Disorders and Stroke (NINDS) in collaboration with the Uniformed Services University (USU), those underlying pathological causes may actually involve more extensive blood vessel damage than previously known. These findings could help target better treatment of these common injuries.

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Research to Prevent Blindness (RPB) is pleased to announce that RPB Stein Innovation Awardee Gregg Semenza, MD, PhD, at Johns Hopkins University School of Medicine, has been named a winner of the 2019 Nobel Prize in Medicine.

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Penn Medicine study shows patients who use online platforms connected to their health records are more likely to take preventative health measures.

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Gregg L. Semenza, M.D., Ph.D., whose discoveries on how cells respond to low oxygen levels have the potential to result in treatments for a variety of illnesses, today was awarded the 2019 Nobel Prize in Physiology or Medicine by the Nobel Assembly at the Karolinska Institutet. He shares the award with scientists William G. Kaelin, Jr., M.D. of the Dana-Farber Cancer Institute and Peter J. Ratcliffe of Oxford University.

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Mealtimes can become a difficult experience for individuals with diabetes. After a meal, blood sugar levels may soar as the food digests or unexpectedly plummet if an insulin dose was more than the meal required.

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After a rigorous vetting process, Johns Hopkins University officials announced today their selection of Vines Architecture to lead the planning stages, known as a feasibility study, for a multidisciplinary building that will honor the legacy of Henrietta Lacks.

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A new test to determine whether antibiotics will be effective against certain bacterial infections is helping physicians make faster and better prescription treatment choices.

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Although cure rates for children with cancer are increasing, cancer treatments can cause permanent deterioration of brain functions leading to impairments in attention, concentration, memory and learning. With the aid of a $3.4 million NIH grant, a Rutgers Cancer Institute of New Jersey investigator and others are exploring an approach that would detect these changes among children with acute lymphoblastic leukemia early during treatment. The goal is to identify a subset of patients who would benefit from a behavioral intervention or treatment clinical trial.

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Common herbs, including lavender, fennel and chamomile, have a long history of use as folk medicines used to lower blood pressure. In a new study, University of California, Irvine researchers explain the molecular mechanisms that make them work.

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A new blood test in development has shown ability to screen for numerous types of cancer with a high degree of accuracy, a trial of the test shows.

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The complex interplay among the arteriovenous grafts, the vessels they connect, and the blood they transport has been difficult to simulate with computers, but one new method provides a way. Researchers report in Physics of Fluids on a series of simulations that reconstructed the fluid dynamics affected by the insertion of an AVG.

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After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.

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Chicago (Sep. 23, 2019): The Association of Pediatric Hematology/Oncology Nurses (APHON) has presented Dr. Deborah A. Lafond, DNP PPCNP-BC CHPPN CPON®, with the 2019 Dr. Casey Hooke Distinguished Service Award. Dr. Lafond’s achievement was officially announced at the 43rd APHON Annual Conference and Exhibit, held September 5-7 in San Jose, CA. This award is presented to an APHON member who has demonstrated excellence to service and to leadership of APHON.

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Chicago (Sep. 23, 2019) The Association of Pediatric Hematology/Oncology Nurses (APHON) announced the recipients of the 2019 APHON Membership Awards at its 43rd Annual Conference and Exhibit, held September 5-7 in San Jose, CA. APHON Membership Awards recognize members who have shown outstanding achievement in their field.

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Chicago (Sep. 23, 2019): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded this year’s Dr. Patricia Greene Leadership Award to Ruth Anne Herring, MSN RN CPNP-AC/PC CPHON®. Herring was presented with this award at the 43rd Annual APHON Conference and Exhibit, held September 5-7, in San Jose, CA.

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Chicago (Sep. 23, 2019): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded Kathleen Ruccione, PhD MPH RN FAAN CPON®, with the 2019 Dr. Nancy E. Kline Mentoring Award. Lafond’s achievement was formally announced at the 43rd Annual APHON Conference and Exhibit, on September 6 in San Jose, CA.

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Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.

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Clinical trial shows potential for some sickle cell patients to be their own stem cell donor.

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10 Things Women Should Know About Preeclampsia

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With the aim of improving pain control and decreasing hospitalizations for vaso-occlusive crisis, the Sickle Cell Team at Children's of Alabama is moving to implement individualized pain plans for patients and pilot an outpatient pain clinic.

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A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25% in a study published today in the New England Journal of Medicine (NEJM).

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Severe bacterial infections are a leading cause of death globally. Delays in effective treatment can increase the chance that a patient dies but treating a patient before blood cultures are drawn may make it impossible to identify the bacteria

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Blood pressure levels in hypertension patients was not improved when they were issued electronic pill bottles or took part in automated texting programs.

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New research in the September 2019 issue of JNCCN—Journal of the National Comprehensive Cancer Network finds that providers with more experience treating people with multiple myeloma have better outcomes than those with more limited experience.

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A $5 million gift from the Edward P. Evans Foundation will create the Edward P. Evans Center for Myelodysplastic Syndromes (MDS) at Dana-Farber Cancer Institute.

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Researchers have developed a novel way to measure how mechanical fatigue affects biological cells. They also have established the important role of this effect in influencing physical properties of biological cells such as red blood cells (RBCs). This new technique assesses the mechanical integrity and fatigue behavior of RBCs using a general microfluidics method that incorporates amplitude-modulated electro-deformation. This method has important applications for mechanical fatigue studies in conjunction with other microenvironments related to health and materials engineering.

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At-home measurements are more accurate, less expensive, and easier to obtain than blood pressure screenings done in medical settings.

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More than 70% of U.S. adults are unaware that human papillomavirus (HPV) causes anal, penile, and oral cancers, according to an analysis led by researchers at The University of Texas Health Science Center at Houston (UTHealth) published in the current issue of JAMA Pediatrics.

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Researchers found that a sleep schedule built to resemble a work week disrupted lipid metabolism and feelings of fullness after a meal. One night's recovery sleep helped... but not enough to return metabolism to normal.

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In patients with high blood pressure resistant to treatment who also have obstructive sleep apnea (OSA), the more severe their OSA, the higher their blood pressure, according to new research published online in the Annals of the American Thoracic Society.

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Papillomavirus has traditionally been considered strictly a sexually transmitted disease, but a recent study found that rabbit and mouse papillomaviruses could be transferred by blood to their respective hosts.

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Patients with acute myeloid leukemia (AML), a leukemia which arises from bone marrow tissue, often see remission following their initial treatment, but for patients whose cancer returns, there are few options. One such option is guadecitabine, a novel DNA hypomethylating drug which slows problematic changes to a person’s epigenetic profile, but the drug is ineffective in a select number of relapsed or refractory AML patients and there has not been a way to determine who stands to benefit and who does not. However, researchers from the Coriell Institute for Medical Research have found certain biomarkers which can indicate a patient’s likelihood for success. Their findings were published in Clinical Epigenetics in July.

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From improving outcomes in children with brain cancer to lowering the risk of damage to the brainstem in children with central nervous system tumors, a pair of new studies published today add to the growing body of research showing the potential benefits of proton therapy.

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For 37 years, Cowboys for Cancer Research has been fundraising to support the fight against cancer. The non-profit group raises funds for research through donations, endowment funds and events like the upcoming Dinner-Dance-Silent Auction.

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The New England Patriots weren't the only team to have a championship season last year. The Tulane University Professional Athlete Care Team (PACT) had its most successful year in 2018-19, as well, completing over 600 patient screenings, including a record 139 former players at Super Bowl LIII in Atlanta.

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Sepsis kills more people every year than heart attacks, breast cancer and other diseases. However, a survey found that most Americans have no idea what it is. Most think it's a hospital-borne illness, but, in fact, 80% of people bring sepsis into the hospital. This releases talks about the signs and symptoms and what to ask your health care provider if you have an infection.

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UNM Cancer Center’s Bone Marrow Transplant program is the first in the state to achieve FACT accreditation, enabling many more New Mexicans with blood disorders to stay home