Feature Channels: Clinical Trials

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Newswise: Hormone-free barrier contraceptive undergoing clinical trial at UC Davis Health
Released: 6-Jun-2024 10:30 AM EDT
Hormone-free barrier contraceptive undergoing clinical trial at UC Davis Health
UC Davis Health

The UC Davis Department of Obstetrics and Gynecology is recruiting potential participants for a clinical trial of an investigational hormone-free monthly intravaginal method of contraception.

Released: 6-Jun-2024 10:05 AM EDT
Breakthroughs in Breast Cancer: Susan G. Komen(R) Scholars and Studies Highlighted at ASCO 2024
Susan G. Komen

Scholars and studies funded by Susan G. Komen(R), the world’s leading breast cancer organization, showcased cutting-edge breast cancer research aimed at advancing the field at the ASCO Annual Meeting 2024. Organized by the American Society of Clinical Oncology, this premier conference annually convenes over 40,000 oncologists and stakeholders worldwide.

Newswise: Groundbreaking LLNL and BridgeBio Oncology Therapeutics collaboration announces start of human trials for supercomputing-discovered cancer drug
5-Jun-2024 6:00 PM EDT
Groundbreaking LLNL and BridgeBio Oncology Therapeutics collaboration announces start of human trials for supercomputing-discovered cancer drug
Lawrence Livermore National Laboratory

In a substantial milestone for supercomputing-aided drug design, Lawrence Livermore National Laboratory (LLNL) and BridgeBio Oncology Therapeutics (BridgeBio) today announced clinical trials have begun for a first-in-class medication that targets specific genetic mutations implicated in many types of cancer.

   
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Released: 5-Jun-2024 5:05 PM EDT
Drug Used to Treat Eczema May Provide Relief for Patients with Intensely Itchy Skin Diseases
University of Maryland School of Medicine

Clinical Trial Finds Oral Medication Significantly Reduced Prurigo Nodularis and Chronic Pruritus of Unknown Origin Symptoms A drug approved to treat eczema provided significant improvement in the symptoms of patients with severe itching diseases that currently have no targeted treatments, according to a new study published in JAMA Dermatology.

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This news release is embargoed until 10-Jun-2024 11:00 AM EDT Released to reporters: 5-Jun-2024 3:05 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 10-Jun-2024 11:00 AM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Newswise: UC San Diego Health First in Region to Provide Novel Therapy for Melanoma
Released: 4-Jun-2024 1:05 PM EDT
UC San Diego Health First in Region to Provide Novel Therapy for Melanoma
UC San Diego Health

Breakthrough one-time cancer treatment option for select patients with metastatic melanoma and solid tumors now offered at UC San Diego Health.

31-May-2024 9:00 AM EDT
Endocrine Society Guideline recommends healthy adults under the age of 75 take the recommended daily allowance of vitamin D
Endocrine Society

Healthy adults under the age of 75 are unlikely to benefit from taking more than the daily intake of vitamin D recommended by the Institutes of Medicine (IOM) and do not require testing for vitamin D levels, according to a new Clinical Practice Guideline issued today by the Endocrine Society.

Released: 1-Jun-2024 8:05 AM EDT
Clinical trials show promise in treating central nervous system lymphoma, breast cancer, and glioblastoma
Dana-Farber Cancer Institute

Dana-Farber Cancer Institute researchers are leading 3 separate studies with encouraging results in treating patients with central nervous system (CNS) lymphoma, breast cancer, and glioblastoma. These findings are among more than 80 studies presented at ASCO that are led by Dana-Farber-affiliated researchers.

30-May-2024 12:05 PM EDT
Experimental Therapy Shows Promise in Pancreatic Cancer Clinical Trial
Lombardi Comprehensive Cancer Center at Georgetown University

Clinicians at Georgetown University’s Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

Newswise: Study Reveals Worse Clinical Outcomes in Breast Cancer Patients Who Reported Higher Pain and Stress
Released: 30-May-2024 4:25 PM EDT
Study Reveals Worse Clinical Outcomes in Breast Cancer Patients Who Reported Higher Pain and Stress
Roswell Park Comprehensive Cancer Center

Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).

Released: 24-May-2024 4:05 PM EDT
Pathways Study Genotype Data, Alliance A011502 Secondary Analysis Headline Roswell Park ASCO24 Presentations
Roswell Park Comprehensive Cancer Center

New insights on improving clinical outcomes and quality of life among breast cancer patients highlight the slate of new research presentations Roswell Park Comprehensive Cancer Center experts will deliver at the American Society of Clinical Oncology (ASCO) Annual Meeting at McCormick Place in Chicago next week.

Released: 21-May-2024 9:05 AM EDT
Donepezil Does Not Improve Chemotherapy-Related Cognitive Impairment
Wake Forest University School of Medicine

Researchers at Wake Forest University School of Medicine conducted a Phase III randomized, placebo-controlled trial to test donepezil, a cognitive-enhancing medicine used in the treatment of Alzheimer’s disease. The research team found that donepezil did not improve memory or other cognitive functions in survivors with cancer-related cognitive impairment.

Released: 20-May-2024 10:00 AM EDT
HSS Launches Clinical Trial to Address Post-Traumatic Osteoarthritis after ACL Revision Surgery
Hospital for Special Surgery

Up to 18% of patients undergoing ACL reconstruction experience graft failure and require revision surgery, which is known to increase the risk of developing post-traumatic osteoarthritis (PTOA).

Released: 20-May-2024 8:55 AM EDT
Clinical trial testing licorice root for prostate cancer begins this spring
University of Illinois Chicago

The University of Illinois Chicago study will be the first to assess whether the natural product has anti-cancer effects that could benefit patients as they await surgical treatment.

Released: 20-May-2024 8:05 AM EDT
Mira Pharmaceuticals Advances Preclinical Trials Towards an IND Submission This Year for Ketamir-2, a Differentiated Oral Ketamine Analog
MIRA Pharmaceuticals, Inc.

MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA) ("MIRA" or the "Company"), a pre-clinical-stage pharmaceutical company focused on the treatment of neurologic and neuropsychiatric disorders, announced that it has advanced new preclinical studies using Ketamir-2, its differentiated oral ketamine analog, towards clinical development for the treatment of severe post-traumatic stress disorder (PTSD) and other leading mental health disorders and neuropathic pain indications.

Newswise: Tricking the Brain’s inner GPS: Grid cells responses to the illusion of self-location
Released: 20-May-2024 12:00 AM EDT
Tricking the Brain’s inner GPS: Grid cells responses to the illusion of self-location
National Research Council of Science and Technology

Dr. Hyuk-June Moon from the Bionics Research Center at the Korea Institute of Science and Technology (KIST), in collaboration with Prof. Olaf Blanke’s team at the Swiss Federal Institute of Technology Lausanne (EPFL), has successfully induced self-location illusions with multi-sensory virtual reality (VR) in the MRI scanner and observed corresponding changes in the human brain's grid cell activity.

Released: 16-May-2024 11:05 AM EDT
Ochsner Health Highlights Innovative Non-Opioid Pain Therapy Candidate Publication
Ochsner Health

A recent publication in Scientific Reports unveils a potentially groundbreaking non-opioid pain treatment developed by a team led by Dr. Hernan Bazan.

Newswise: Project Could Transform Clinical Trials for Pediatric Brain Tumors
Released: 13-May-2024 6:05 AM EDT
Project Could Transform Clinical Trials for Pediatric Brain Tumors
Children's Hospital Los Angeles

Randomized controlled trials have long been the gold standard for evaluating new therapies. But for pediatric brain tumors, it can be difficult—if not impossible—to enroll the large numbers of patients needed for these studies.

Newswise: Sylvester Cancer Launches New Brain Tumor Institute to Personalize Brain Cancer Treatment
Released: 8-May-2024 9:05 PM EDT
Sylvester Cancer Launches New Brain Tumor Institute to Personalize Brain Cancer Treatment
Sylvester Comprehensive Cancer Center

Sylvester Comprehensive Cancer Center today announced establishment of the Sylvester Brain Tumor Institute. It will focus on personalized medicine approaches for treating all patients with brain tumors.

Newswise: ChatGPT can extract data from clinical notes
Released: 8-May-2024 12:05 PM EDT
ChatGPT can extract data from clinical notes
UT Southwestern Medical Center

ChatGPT, the artificial intelligence (AI) chatbot designed to assist with language-based tasks, can effectively extract data for research purposes from physicians' clinical notes, UT Southwestern Medical Center researchers report in a new study. Their findings, published in NPJ Digital Medicine, could significantly accelerate clinical research and lead to new innovations in computerized clinical decision-making aids.

Released: 6-May-2024 11:30 AM EDT
Society for Clinical Trials Presents E-MOTIVE Trial with Prestigious David Sackett Trial of the Year Award
Society for Clinical Trials

The Society for Clinical Trials (SCT) is pleased to announce that the prestigious David Sackett Trial of the Year Award will be presented to the ”Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage (E-MOTIVE).”

Newswise: MedStar Health Launches Participation in Phase 3 MAGNITUDE 
Gene-Editing Study with First U.S. Heart Patient Treated at 
MedStar Washington Hospital Center
Released: 2-May-2024 8:55 AM EDT
MedStar Health Launches Participation in Phase 3 MAGNITUDE Gene-Editing Study with First U.S. Heart Patient Treated at MedStar Washington Hospital Center
MedStar Washington Hospital Center

The first U.S. heart patient involved in a study for a new gene-editing therapy has successfully been treated at MedStar Washington Hospital Center.

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Released: 2-May-2024 12:05 AM EDT
Getting Under the Skin at May 11 Symposium on Melanoma
Cedars-Sinai

The Angeles Clinic and Research Institute, an affiliate of Cedars-Sinai Cancer, is teaming up with the AIM at Melanoma Foundation for the 14th year to host a free melanoma symposium for patients, caregivers and clinicians.

Newswise: Sylvester Cancer Adding Cellular Therapy to Its Arsenal Against Metastatic Melanoma
Released: 1-May-2024 5:05 PM EDT
Sylvester Cancer Adding Cellular Therapy to Its Arsenal Against Metastatic Melanoma
Sylvester Comprehensive Cancer Center

Patients in South Florida with metastatic melanoma will soon have access to tumor-infiltrating lymphocyte therapy, or TIL. The therapy will be available at Sylvester Comprehensive Cancer Center and will be South Florida’s only center offering this treatment.

Released: 1-May-2024 2:05 PM EDT
Wake Forest University School of Medicine Approved for $1 Million in PCORI Funding for Patient Subgroup Discovery Study
Wake Forest University School of Medicine

Researchers at Wake Forest University School of Medicine have been approved for a $1 million award by the Patient-Centered Outcomes Research Institute (PCORI) for a methodology study.

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Released: 30-Apr-2024 6:05 PM EDT
April Monthly Research Highlights Newsletter
Cedars-Sinai

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for April 2024.

Released: 30-Apr-2024 10:05 AM EDT
Moffitt Initiates Groundbreaking Clinical Trial with Oncolytic Virus for Non-Small Cell Lung Cancer
Moffitt Cancer Center

Moffitt Cancer Center has launched a pioneering clinical trial for patients with late-stage non-small cell lung cancer whose disease has progressed following initial frontline standard of care immunotherapy that includes an immune checkpoint inhibitor alone or combined with chemotherapy.

Newswise: AACR: Novel immunotherapies show promise for patients with kidney cancer and for solid organ transplant recipients with skin cancer
4-Apr-2024 3:00 PM EDT
AACR: Novel immunotherapies show promise for patients with kidney cancer and for solid organ transplant recipients with skin cancer
University of Texas MD Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center presented encouraging findings today from two clinical trials in a plenary session highlighting advances in novel immunotherapy approaches at the American Association for Cancer Research (AACR) Annual Meeting 2024.

   
3-Apr-2024 10:05 AM EDT
AACR: Preliminary study finds immunotherapy combination before surgery improves outcomes for patients with pancreatic cancer
University of California, Los Angeles (UCLA), Health Sciences

A pilot study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that for people with borderline resectable pancreatic cancer, administrating an immunotherapy drug in combination with chemotherapy before surgery is safe and may improve long-term outcomes.

Released: 3-Apr-2024 6:05 PM EDT
Tip Sheet: Weight loss drugs and cancer prevention, Fred Hutch at AACR, lymphedema Q&A — and new vice president and chief nursing officer
Fred Hutchinson Cancer Center

SEATTLE — April 3, 2024 — Below are summaries of recent Fred Hutchinson Cancer Center research findings, patient stories and other news. If you’re covering the American Association for Cancer Research (AACR) Annual Meeting, please see our list of and contact to set up interviews.

Newswise: Wilmer Eye Institute Awarded More Than $20 Million for Clinical Trial Investigating Genetic Eye Condition
Released: 3-Apr-2024 10:00 AM EDT
Wilmer Eye Institute Awarded More Than $20 Million for Clinical Trial Investigating Genetic Eye Condition
Johns Hopkins Medicine

The Wilmer Eye Institute, Johns Hopkins Medicine has received two awards totaling more than $20 million from the National Eye Institute at the National Institutes of Health, both of which will be used for a six-year clinical trial investigating a potential treatment for the most common inherited retinal disease, retinitis pigmentosa.

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Released: 3-Apr-2024 1:05 AM EDT
Curtis L. Cetrulo, Jr., MD, Selected as Lyon Family Chair in Plastic Surgery
Cedars-Sinai

Curtis L. Cetrulo Jr., MD, vice chair of Research in the Department of Surgery and director of the Division of Plastic Surgery, has been selected as the General William and Willa Dean Lyon Family Chair in Reconstructive and Plastic Surgery.

Released: 2-Apr-2024 4:00 PM EDT
One in five people with cancer participate in medical research studies
Fred Hutchinson Cancer Center

Researchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released new findings in the Journal of Clinical Oncology showing that when all types of cancer research studies are considered, at least one in five people with cancer in the U.S., or 21.9%, participate in some form of clinical research.

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This news release is embargoed until 1-Apr-2024 5:05 PM EDT Released to reporters: 1-Apr-2024 5:05 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 1-Apr-2024 5:05 PM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Newswise:Video Embedded yale-cancer-center-experts-scientists-to-share-vision-and-research-at-leading-conference
VIDEO
Released: 1-Apr-2024 2:05 PM EDT
Yale Cancer Center Experts, Scientists to Share Vision and Research at Leading Conference
Yale Cancer Center/Smilow Cancer Hospital

The five-day session (April 5-10), themed as “Inspiring Science. Fueling Progress. Revolutionizing Care,” will include new findings from Yale Cancer Center researchers.

Released: 1-Apr-2024 10:05 AM EDT
UChicago Medicine: NCI renews Cancer Center's premier 'Comprehensive' designation amid 50th anniversary celebration
University of Chicago Medical Center

A 'Comprehensive Cancer Center' is the top U.S. designation for cancer research and treatment facilities recognized by high-quality research that leads to major shifts in cancer care.

Newswise: Study explores the future of at-home cancer treatment
Released: 28-Mar-2024 12:00 PM EDT
Study explores the future of at-home cancer treatment
Keck Medicine of USC

A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.

Newswise: Combining Epigenetic Cancer Medications May Have Benefit for Colorectal Cancers and Other Tumor Types
27-Mar-2024 1:30 PM EDT
Combining Epigenetic Cancer Medications May Have Benefit for Colorectal Cancers and Other Tumor Types
Van Andel Institute

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published today in Science Advances.

Newswise: Gene Therapy Offers Hope for Giant Axonal Neuropathy Patients
Released: 27-Mar-2024 12:05 PM EDT
Gene Therapy Offers Hope for Giant Axonal Neuropathy Patients
UT Southwestern Medical Center

A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports. Findings from the phase one clinical trial, published in the New England Journal of Medicine, could offer hope for patients with this rare condition and a host of other neurological diseases.

Released: 27-Mar-2024 10:05 AM EDT
UCI Health celebrates transformational acquisition of four community hospitals
University of California, Irvine

UCI Health, the clinical enterprise of the University of California, Irvine, has completed the acquisition of four hospitals and associated outpatient locations from Tenet Healthcare Corporation.

Newswise: Empowering Minority Cancer Patients: Tips for Advocacy and Support
Released: 27-Mar-2024 9:05 AM EDT
Empowering Minority Cancer Patients: Tips for Advocacy and Support
Rutgers Cancer Institute

Mariam F. Eskander, MD, MPH, surgical oncologist in the Gastrointestinal Oncology Program at Rutgers Institute of New Jersey, offers insight and tips for minority individuals navigating a cancer diagnosis and how we can all work together to mitigate cancer disparities.

Newswise: 10 Facts about Head & Neck Cancers
Released: 27-Mar-2024 9:05 AM EDT
10 Facts about Head & Neck Cancers
Rutgers Cancer Institute

Head and neck cancer is the term used to describe a number of different malignant tumors that develop in or around the throat, larynx, nose, sinuses and mouth.

Released: 25-Mar-2024 12:05 PM EDT
Friend or foe: A closer look at the role of health care algorithms in racial and ethnic disparities
Perelman School of Medicine at the University of Pennsylvania

For years, it was harder for Black patients to secure a coveted spot on the national kidney transplant waitlist because a clinical algorithm was making Black patients appear healthier than they were.

Newswise: Inflammation-Reducing Drug Shows No Benefit for Dry Age-Related Macular Degeneration in Nih Trial
Released: 21-Mar-2024 11:30 AM EDT
Inflammation-Reducing Drug Shows No Benefit for Dry Age-Related Macular Degeneration in Nih Trial
NIH, National Eye Institute (NEI)

The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health.

Released: 21-Mar-2024 7:05 AM EDT
ScienceMedia Welcomes Visionary Leaders to Advisory Board, Paving the Way for a New Era of Innovation
ScienceMedia

ScienceMedia, a global SaaS provider redefining the landscape of clinical mastery in the biotech and pharma industries, announces the formation of its inaugural advisory board.

Released: 20-Mar-2024 5:05 PM EDT
Adding ribociclib to hormone therapy reduces the risk of breast cancer recurrence
University of California, Los Angeles (UCLA), Health Sciences

A new treatment approach that combines a targeted therapy drug with hormone therapy significantly increased the amount of time a person with stage 2 or 3 HR-positive, HER2-negative early breast cancer lives without the cancer returning, according to a new study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators.

Released: 19-Mar-2024 11:05 AM EDT
ATS 2024 Conference Program is Live! Register Now for Scientific Sessions in Pulmonary, Critical Care and Sleep Medicine
American Thoracic Society (ATS)

The ATS 2024 International Conference Program is now live! Get ready for a series of dynamic scientific programming with presentations covering AI in thoracic medicine, the basic sciences, research breakthroughs and clinical treatment, as well as spotlighting the next generation of innovators in pulmonary, critical care and sleep medicine.

Released: 19-Mar-2024 10:05 AM EDT
Chop Researchers Find Branched Chain Amino Acid Supplementation May Aid in Concussion Recovery
Children's Hospital of Philadelphia

In the first clinical trial of a targeted pharmacologic therapeutic for mild traumatic brain injury in pediatric patients, scientists have found preliminary evidence that adolescents and young adults with concussion who take a specific formulation of branched chain amino acid (BCAA) supplements after injury experience faster symptom reduction and return to physical activity.

Newswise: Role in mitochondrial metabolism paints more complete picture of MCL-1 function
Released: 18-Mar-2024 3:05 PM EDT
Role in mitochondrial metabolism paints more complete picture of MCL-1 function
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital have uncovered a metabolic role for cell-survival protein MCL-1, potentially explaining previous clinical trial setbacks.



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