Feature Channels: Dermatology

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Using genetic and pharmacological means, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) were surprised to find that blocking LDHA had only a limited impact on melanoma cells, since they were able to redirect energy production. Their results identify an alternative growth pathway driven by a molecule called ATF4, revealing new potential targets for drug development. The study was published today in EMBO Journal.

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If you’ve ever gone to bed with clear skin and woken up with a massive, painful pimple on your face, you’re not alone. According to dermatologists from the American Academy of Dermatology, acne is the most common skin condition in the United States, affecting up to 50 million Americans annually. Although acne comes in many forms, including blackheads and whiteheads, the most severe type of acne is a pimple that develops deep in the skin, causing a red, swollen and painful bump. Fortunately, say dermatologists, there are ways to tackle this type of acne at home to alleviate pain and reduce the pimple’s size, swelling and redness.

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Mayo Clinic physicians Matthew Block, M.D., Ph.D. and Tina Hieken, M.D., have received a Stand up to Cancer (SU2C) Catalyst Award to fund melanoma research and a neoadjuvant clinical trial.

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Being a teenager can be tough. Teens must manage high school and the pressures of adolescence while at the same time battling stubborn acne.

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The latest research, features and announcements in healthcare in the Healthcare News Source

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Patient satisfaction after plastic surgery is most affected by surgeon-related factors, such as taking the time to answer questions and including patients in the decision-making process, reports a study in the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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Chiggers, redbugs, harvest mites – whatever you call them, they are pesky little bugs whose bites cause really itchy rashes, usually around the ankles and waistline.

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The stigma associated with the autoimmune disease psoriasis may lead people to avoid patients who show signs of the condition, including not wanting to date, shake hands, or have people in their homes if they suffer from the disease. New multidisciplinary research involving both psychologists and dermatologists from the Perelman School of Medicine at the University of Pennsylvania is the first to examine how common this stigma may be among the general population of the United States as well as among medical students.

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Scientists at The University of Texas at El Paso have received nearly $6 million from the National Institutes of Health (NIH) to improve treatment and develop new diagnostic tools to assess post-therapeutic outcomes for patients with Chagas disease.

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Michael Kolodney, who chairs West Virginia University’s Department of Dermatology, has developed a smartphone app to cultivate that intuition in medical students sooner. An initial study suggests that the app, called Skinder, may improve how accurately medical students diagnose melanomas.

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A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer.

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The University of Alabama at Birmingham has been awarded nearly $18.9 million by the National Institutes of Health Countermeasures Against Chemical Threats Program and National Institute of Environmental Health Sciences to support the UAB Research Center of Excellence in Arsenicals.

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O uso de barro ou argila úmida como tratamento de pele tópico ou emplastro é uma prática comum em algumas culturas e o conceito de usar argila como medicamento vem dos tempos antigos. Agora, pesquisadores da Mayo Clinic e seus colaboradores na Arizona State University descobriram que pelo menos um tipo de argila pode ajudar a combater bactérias causadoras de doenças em feridas, incluindo algumas bactérias resistentes a tratamento. Os resultados foram publicados no International Journal of Antimicrobial Agents.

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Maple trees are best known for their maple syrup and lovely fall foliage. But it turns out that the beauty of those leaves could be skin-deep — and that’s a good thing. Today, scientists report that an extract from the leaves may prevent wrinkles.

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Many parents worry that teens may not consider potential health risks, how a tattoo may impact them professionally or the chance that as they age and mature, they may regret getting a permanent tattoo.

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Researchers from the George Washington University published an article in Trends in Parasitology outlining their lessons learned while creating vaccine candidates for hookworm and schistosomiasis.

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Faculty at The University of Texas Health Science Center at Houston (UTHealth) discuss the diagnosis and treatment of scleroderma, an autoimmune disease affecting an estimated 300,000 people in the United States.

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According to dermatologists from the American Academy of Dermatology, scalp conditions, such as alopecia areata, psoriasis and seborrheic dermatitis, are very common. In fact, researchers estimate that at least half of the people who have plaque psoriasis have it on their scalp. Fortunately, patients can improve their conditions using topical medications prescribed by their dermatologist. While these medications can come in many forms, including shampoos, lotions, sprays and oils, the most popular are solutions, which are liquid-based, and foams.

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Lamont R. Jones, M.D., MBA, vice chair for the Department of Otolaryngology - Head and Neck Surgery at Henry Ford Health System, received a five-year, $895,814 grant from the National Institutes of Health to fund a research project titled, "Characterization of Keloid Specific Exosomes and Determination of Exosomal Critical Signaling Pathways in the Keloid Microenvironment."

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Checkpoint inhibitor therapies have made metastatic melanoma and other cancers a survivable condition for 20 to 30 percent of treated patients, but clinicians have had very limited ways of knowing which patients will respond. Researchers have uncovered a novel mechanism by which tumors suppress the immune system. Their findings also usher in the possibility that a straightforward blood test could predict and monitor cancer patients’ response to immunotherapy.

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The Myositis Association is pleased to announce the appointment of Mary McGowan as Executive Director.

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Researchers have found an important contributor to heart pathology caused by the cancer drug doxorubicin — disruption of metabolism that controls immune responses in the spleen and heart. This allows chronic, non-resolving inflammation that leads to advanced heart failure.

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Every parent wants their child to feel comfortable in their own skin, but this can seem impossible if that child is afflicted with bad acne or constantly itching from eczema. Such conditions take a terrible toll, as Adelaide Hebert, M.D., professor and director of pediatric dermatology at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), knows only too well.

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Three-dimensional image simulation is popular among women planning breast augmentation surgery. But while this evolving technology may enhance communication, it doesn’t improve patient satisfaction with the results of the procedure, reports a paper in the August issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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In a series of experiments with mice, Johns Hopkins investigators have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol.

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For more than 30 years, board-certified dermatologists have been providing free skin cancer screenings in their communities through the AAD’s SPOTme® program — and research published today highlights the value of that program.

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They say you are what you eat, but it’s not quite that simple when it comes to healthy skin.

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While people of any skin tone can develop skin cancer, specific risk factors in organ transplant patients may vary based on their race.

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A board-certified dermatologist can evaluate patients’ conditions and provide them with the best possible treatment.

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Patient Karolina Jasko discusses her experience with nail melanoma, which is often overlooked and diagnosed late, resulting in a poor prognosis.

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While Botox may be most commonly known for its usefulness as a cosmetic anti-aging treatment, what’s not nearly as well-known is that cosmetics were not the original intention of the substance. Dig a little deeper and you might be surprised to find out just how many uses the substance has in other areas of medicine.

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Enzo is pleased to announce the launch of a new primary antibody validated for IHC, our p16INK4a monoclonal antibody. Our antibody is specific to the p16INK4A protein, a cyclin-dependent kinase inhibitor that plays an important regulatory role in the cell cycle.

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Biotin supplementation, in the common dosage of 10 mg per day, can interfere with immunoassays leading to incorrect laboratory results and the potential for clinical misinterpretation.

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Recognizing your limits, knowing where you’re going and what you might encounter there, and being aware of the environment you’re in are the best ways to avoid the bites, stings, cuts, sprains and other mishaps that can spoil outdoor activities

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Scientists at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

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Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay – sometimes even after treatment has concluded.

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Suzanne Olbricht, MD, Chief of Dermatology at Beth Israel Deaconess Medical Center, shares tips for avoiding sunburns.

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A new study published in Annals of Allergy, Asthma and Immunology shows that eczema symptoms can have a profoundly negative impact on quality of life for those who suffer – even worse than for those with common chronic illnesses like heart disease, diabetes and high blood pressure.

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Varicose veins affect about 25 percent of women and 15 percent of men in their lifetime, and there are many ways they can be treated.

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Skin cancer is the most common cancer in the United States, affecting one in five Americans in their lifetime. To help raise awareness of skin cancer prevention and detection, 12 dermatologists, skin cancer survivors, and their family and friends will tell “Skin Cancer, Take a Hike!” during a four-day trek through remote Alaska. Starting Sunday, July 15, the hikers will trek more than 20 miles along Alaska’s Denali and Foraker mountains to raise funds for the American Academy of Dermatology’s SPOT Skin Cancer™ campaign. Proceeds raised through Skin Cancer, Take a Hike!™ will support community outreach programs and services, including free skin cancer screenings, shade structures where children learn and play, and sunscreen dispensers in public pools and parks.

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Adam Friedman, MD, professor of dermatology at the GW School of Medicine and Health Sciences, and his team investigated the use of nanotechnology to improve efinaconazole treatment and make it more cost effective.

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The world’s leading ocular oncology scientists and clinicians are meeting this summer to discuss the latest research and treatment developments in eye cancer. The Ocular Oncogenesis and Oncology Conference (OOO) will be held by the Association for Research in Vision and Ophthalmology (ARV0) in partnership with the Champalimaud Foundation, July 18 – 21 at the Champalimaud Centre for the Unknown in Lisbon, Portugal

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Cuts from a sharp knife or a piece of glass are very common. They often occur while people are preparing food, washing dishes or even crafting. All it takes is a slip of the knife or a dish breaking, and suddenly there’s blood. However, while these types of cuts are startling, most can be safety treated at home, according to dermatologists from the American Academy of Dermatology.

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New research shows that death and recurrence are rare in children with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), but children who experience these skin conditions have high rates of complications and that treatment strategies varied among health care providers.

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Brian C. Capell, MD, PhD, an assistant professor of Dermatology in the Perelman School of Medicine at the University of Pennsylvania, a core faculty member of the Penn Epigenetics Institute, and a member of the Abramson Cancer Center, has been awarded a prestigious Damon Runyon Clinical Investigator Award for 2018.

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An article published today in the Journal of the American Academy of Dermatology reviews the available research into chemical ultraviolet filters found in U.S. sunscreens.

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Embrace the Sun recommends non-burning sun exposure, citing research on sun exposure, vitamin D, and disease risk.