Feature Channels: Diabetes

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Joslin Diabetes Center scientists discover new route by which high blood glucose levels damage eyes.

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Cellular phones have taken on many new roles in recent years. Now researchers at Saint Louis University and Old Dominion University say smartphones can be used to help elderly diabetics manage their health and learn more about their condition.

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Intensive lifestyle changes aimed at modest weight loss reduced the rate of developing type 2 diabetes by 34 percent over 10 years in people at high risk for the disease.

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Researchers from the University of Manitoba report that whole yellow pea flour can be used as an ingredient to produce low-glycemic foods that may help those with diabetes, according to a new study from the Journal of Food Science, published by the Institute of Food Technologists.

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Mayo Clinic clinicians and designers, along with colleagues from other institutions, have developed and tested a tool to involve patients more in their diabetes treatment and medication choices. The tool, a set of decision aid cards, could help patients make decisions involving their disease and perhaps lead to better outcomes.

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A study, published online in the journal Current Medical Research and Opinion, showed that a greater percentage of patients with type 2 diabetes treated with the fixed-dose combination ACTOplus met (pioglitazone HCl and metformin HCl) as initial therapy reached the study goal of hemoglobin A1c (HbA1c) of ≤7 percent compared to either component alone. Safety and tolerability of ACTOplus met therapy were evaluated by rate of drug discontinuation and treatment-emergent adverse events.

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A naturally produced molecule called resveratrol, found in the skin of red grapes, has been shown to lower insulin levels in mice when injected directly into the brain, even when the animals ate a high-fat diet.

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Surgeons from St. Michael’s Hospital, Toronto, and the University of Toronto have observed that sepsis and sepsis-related mortality are linked to a naturally occurring hormone found in visceral adipose tissue. The implications of the study results may assist in developing methods of both predicting and decreasing sepsis and sepsis-related complications.

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Individuals living in neighborhoods conducive to physical activity and providing access to healthy foods may have a lower risk of developing type 2 diabetes in a five-year period, according to a report in the October 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

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MedTagger.com – a new online community that combines social networking and search technology to provide trusted, relevant information to the global diabetes community – is hosting an exclusive webcast presentation on Wednesday, October 14 at 12:00 noon ET (9:00 am PT).

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St. Jude Children’s Research Hospital investigators have discovered how destructive immune cells gain access to insulin-producing cells and help cause diabetes. The finding points to possible new strategies to halt or prevent type I diabetes.

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A new study accepted for publication in Endocrinology, a journal of The Endocrine Society, shows that the brain plays a key role in mediating resveratrol’s anti-diabetic actions, potentially paving the way for future orally-delivered diabetes medications that target the brain.

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Fat and muscle mass, as potentially determined by a person’s ethnic background, may contribute to diabetes risk, according to a new study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

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Mathematicians Have Developed Powerful New Tools for Winnowing Out the Genes Associated with Diabetes.

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When Sonia Sotomayor was named Supreme Court nominee, the type 1 diabetes community seized the news as proof that diabetes is no longer a life-limiting condition.

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Nutrition scientists at UMass Amherst have identified the molecular pathway by which foods rich in soy bioactive compounds, or isoflavones, to lower diabetes and heart disease risk. Soy foods can lower cholesterol, decrease blood glucose levels and improve glucose tolerance in people with diabetes.

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Mayo Clinic has repeatedly been ranked #1 in endocrinology by annual U.S. News and Report medical surveys. An excellent story is our work toward finding a means of regenerating insulin-producing tissue through iPSC or induced pluripotent stem cells.

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Weight management underlies a successful new approach to type 2 diabetes care at Joslin Diabetes Center.

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Patients with diabetic vascular disease have increased chances to develop blockages in their arteries secondary to peripheral vascular disease. These blockages can be very serous. Medical professionals and diabetic patients can learn more by accessing the SVS’ comprehensive vascular health information provided through social media and online resources.

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Using hyperbaric oxygen therapy to heal chronic non-healing wounds associated with diabetes proves to be successful and painless.

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In recognition of World Diabetes Day on November 14th, the Making Sense of Diabetes video contest is challenging people living with diabetes to visually reveal its impact on their lives through one of the five senses: sight, hearing, taste, touch or smell. The contest is sponsored by the Diabetes Hands Foundation, a pioneering advocacy organization in social media, and made possible through support provided by Boehringer Ingelheim Pharmaceuticals, Inc.

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Ling Qi, Assistant Professor of Nutritional Science at Cornell University, is studying the link between obesity and diabetes.

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St. Jude Children's Research Hospital investigators find that adults who survived cancer as children exercise less, increasing risk of diabetes, obesity and heart disease.

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Baylor Health Care System is reaching out to the traditionally underserved neighborhood, transforming a local recreation center into the area’s first and only diabetes health and wellness institute. South Dallas residents are 30 percent more likely to be admitted to a hospital due to diabetes or a diabetes-related condition than other city residents.

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New research demonstrates the importance of treating pregnant women with even the mildest forms of gestational diabetes to reduce healthcare risks for both infants and mothers.

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For men with type 2 diabetes, a cell type linked to allergic inflammation is closely linked to a key indicator of diabetic kidney disease (nephropathy), suggests a study in the November Clinical Journal of the American Society of Nephrology (CJASN).

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In a study of adults diagnosed with type 2 diabetes, those who participated in a supervised tai chi exercise program two days a week with three days of home practice for six months significantly lowered fasting blood glucose levels.

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Treating pregnant women for mild gestational diabetes resulted in fewer cesarean sections and other serious birthing problems associated with larger than average babies, according to a study conducted in part at the University of North Carolina at Chapel Hill.

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Insulin resistance, the hallmark of type 2 diabetes and a condition often associated with obesity, is paradoxically also an apparent contributor to muscle wasting and severe fat loss that accompanies some cancers, according to new research.

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There is new evidence that depression, obesity and alcohol abuse or dependency are interrelated conditions among young adult women but not men.

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Researchers have long suspected that overweight people tend to have large fat deposits in their pancreases, but they’ve been unable to confirm or calculate how much fat resides there because of the organ’s location.

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A study led by Johns Hopkins researchers found that when African Americans and whites live in similar environments and have similar incomes, their diabetes rates are similar, which contrasts with the fact that nationally diabetes is more prevalent among African Americans than whites.

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In patients with recent onset type-2 diabetes, treatment with insulin or the diabetes drug metformin did not reduce inflammatory biomarkers, such as high-sensitivity C-reactive protein, although the treatment did improve glucose control, according to a study in the September 16 issue of JAMA.

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1) Metformin is more effective than chemotherapy alone; 2) Study supports cancer stem cells hypothesis; 3) Laboratory study focused on breast cancer cells.

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Researchers have discovered a molecular circuit involving the oxygen-carrying component of hemoglobin -- heme -- that helps maintain proper metabolism in the body, providing new insights into metabolic disorders such as obesity and diabetes. This happens through a molecular pathway that allows the cell to monitor and adjust internal heme levels via Rev-erbα, creating more when heme levels fall, and slowing it down when levels rise.

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A breakthrough by an international team of researchers in Canada, France, the UK and Denmark has uncovered a new gene that could lead to better treatment of type 2 diabetes, as well as a better understanding of how this widespread disease develops. Their study will be published in Nature Genetics Sept. 6.

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People with type 2 diabetes are not consuming sufficiently healthy diets and could benefit from ongoing nutritional education and counseling, according to a new study by researchers at Wake Forest University School of Medicine and colleagues.

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A moderate aerobic exercise program, without weight loss, can improve insulin sensitivity in both lean and obese sedentary adolescents, according to a new study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

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Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know why.

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The Society for Vascular Surgery is responding to President Barack Obama’s remarks regarding diabetic foot care on August 11, 2009 at a town hall meeting in New Hampshire. The President’s statement does not accurately reflect the actual reimbursement to the surgeon for this procedure; surgeons receive reimbursement of less than $1,000, which includes follow-up care provided for 90 days after the operation.

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Medicare patients with heart conditions and diabetes, or who require cancer screenings, are getting better treatment than ever at the University of Michigan Health System and that care is costing less, according to a new report.

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Researchers from North Carolina State University and the Mayo Clinic have developed a computer model that medical doctors can use to determine the best time to begin using statin therapy in diabetes patients to help prevent heart disease and stroke.

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Two new guides released today can help women with gestational diabetes and their doctors make informed decisions about different treatments for the condition. Gestational diabetes is a potentially dangerous condition that affects 7 out of 100 pregnant women.

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People diagnosed with type 2 diabetes often resist taking insulin because they fear gaining weight, developing low blood sugar and seeing their quality of life decline.

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Childhood cancer survivors treated with total body or abdominal radiation may have an increased risk of diabetes, according to a report in the August 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. This correlation does not appear to be related to patients' body mass index or physical inactivity.

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Researchers at the Joslin Diabetes Center have linked another gene to a rare form of diabetes, a finding that could prove beneficial to those with the more common type 2 diabetes.

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A research team led by Dr. Tony Lam at the Toronto General Research Institute and the University of Toronto discovered a novel function of a hormone found in the gut that might potentially lower glucose levels in diabetes.

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Short sleep times, experienced by many individuals in Westernized societies, may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may increase the long-term risk of diabetes, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

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Taking the most commonly-prescribed anti-diabetic drug, metformin, reduces an individual's risk of developing pancreatic cancer by 62 percent, according to research from The University of Texas M. D. Anderson Cancer Center, published in the Aug. 1 issue of Gastroenterology.

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Pediatric researchers have found that a gene previously shown to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a possible genetic influence on how prenatal events may set the stage for developing diabetes in later childhood or adulthood.