Bioengineers have developed a portable, non-invasive monitor that can determine, in one minute and without drawing blood, whether chemotherapy patients have a reduced number of white blood cells that could lead to infections.
The West Big Data Innovation Hub (WBDIH) at the San Diego Supercomputer Center (SDSC) at UC San Diego is one of four regional big data hubs partner sites awarded a $1.8 million grant from the National Science Foundation (NSF) for the initial development of a data storage network during the next two years.
The team examined city water policies over the course of four years to create a database of water conservation policies. They also developed an associated index of the number of different categories of policies each city adopted and gathered data on the climate, water sources, population, economy and political leanings.
Researchers at the Georgia Institute of Technology have found new evidence suggesting that batteries based on sodium and potassium hold promise as a potential alternative to lithium-based batteries.
Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease (ILD).
Researchers at the Princess Margaret Cancer Centre in Toronto have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone. The study, which will be published June 19 in the Journal of Cell Biology, suggests that inhibiting these proteins with drugs could prevent the development of breast cancer in women at high risk of the disease.
Researchers at The Francis Crick Institute in London have discovered that cells can trap viruses in a protein cage to stop them from spreading to neighboring cells. The study, which will be published June 19 in the Journal of Cell Biology, reveals that the vaccinia virus can escape this trap by recruiting additional proteins to dismantle the cage and propel the virus out of the cell.
A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment.
"This new method should allow us to explore a large ‘chemical space’ that had been essentially off-limits."
Faculty member Glenn McClure has received a $50,000 National Science Foundation Innovation Corps-National Innovation Network Teams grant to explore the interpretation and representation of large amounts of data through non-speech audio such as music.
A new study by Scripps Research, published today in Nature Communications, suggests scientists could build better drugs by learning from bacteria-derived molecules called thiocarboxylic acids.
A new study from the Keck School of Medicine of USC shows that African-Americans and Latinos who are diagnosed with diabetes after age 50 have a more than threefold risk of developing pancreatic cancer.
A new Food-PRICE study finds persistent nutritional disparities within the food choices of those receiving assistance under the Supplemental Nutrition Assistance Program (SNAP) compared to those not receiving SNAP assistance.
Graphene electrodes could enable higher quality brain imaging thanks to new research by a team of engineers and neuroscientists at UC San Diego. The researchers developed a technique, using platinum nanoparticles, to lower the impedance of graphene electrodes by 100 times while keeping them transparent. In tests on transgenic mice, the electrodes were able to record and image neuronal activity (calcium ion spikes) at of large groups of neurons and individual brain cells.
Working with hundreds of time-lapse videos of mouse tissue, a team of biologists joined up with civil engineers to create what is believed to be the first 3D computer model to show precisely how the tiny tubes that funnel milk through the breasts of mammals form.
Researchers led by the University of Michigan Rogel Cancer Center have identified a new subtype of prostate cancer that occurs in about 7 percent of patients with advanced disease. This subset of tumors were responsive to immunotherapy treatment.
Obesity, cardiovascular disease, and cancer often begin with early, subtle changes in cell metabolism. Now researchers at Tufts University have developed a non-invasive optical imaging technique that detects these changes, providing an early window of opportunity for new research and potential therapeutic development.
The world needs more students trained in global, interdisciplinary health science research. The International Research Experience for Students (IRES) program provides an eight-week-long opportunity for students to get lab experience abroad. One group is in Singapore this summer studying nanotechnology and virus detection.
Systems biology was used to identify previously unknown protein targets of plant pathogens in Arabidopsis thaliana, employing some of the same methods used to analyze social networks. This theoretical framework could help analyze other interactions between species to reveal pathogen contact points.
a team led by researchers at UC San Diego’s Department of Chemistry and Biochemistry and the San Diego Supercomputer Center (SDSC), has used machine learning techniques to develop models for simulations of water with “unprecedented accuracy.”
As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent. The findings, published in a research letter in Nature Genetics, contain significant implications for which men may need to be regularly screened because of higher genetic risk of prostate cancer.
A theorized but never-before detected property of quantum matter has now been spotted in the lab.
Changes in cellular struts called microtubules can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.
Oxygen photosynthesis has to be the greatest giver of life on Earth, and researchers have cracked yet another part of its complex and efficient chemistry. The more we know about it, the better we may be able to tweak photosynthesis, if it comes under environmental duress. It's also a great teacher of how to harvest sheer unlimited energy from the sun.
Researchers at Indiana University have made the first direct observation of how bacteria use appendages thousands of times thinner than a human hair to absorb DNA in the environment. The work could help advance efforts stop antibiotic resistant bacteria.
Vanderbilt University has been awarded a five-year, $8.1-million grant from the National Cancer Institute to serve as a research center in the institute’s prestigious Cancer Systems Biology Consortium for the study of small cell lung cancer.
A new study led by public health researchers at Tufts University School of Medicine reports significant food insecurity for adults on probation in Rhode Island. Nearly three-quarters of the participants experienced food insecurity over a 30-day period, with almost half having very low food security.
A research team at Wayne State University hopes to give clinicians tools for identifying the early signs of impending disease by measuring subtle deviations in the way the brain modulates its chemistry during the formation of new memories. Their research project, “Task-related modulation of hippocampal glutamate, subfield volumes and associative memory in younger and older adults: a longitudinal ¹H FMRS study,” was recently awarded a two-year, $423,500 grant from the National Institute on Aging of the National Institutes of Health.
Machine learning using real-time symptom reports can accurately detect lymphedema, a distressing side effect of breast cancer treatment that is more easily treated when identified early, finds a new study led by NYU Rory Meyers College of Nursing and published in the journal mHealth.
The number of insurance denials for life-saving hepatitis C drugs among patients with both private and public insurers remains high across the United States. Private insurers had the highest denial rates, with 52.4 percent of patients denied coverage, while Medicaid denied 34.5 percent of patients and Medicare denied 14.7 percent.
Mucus and other airway secretions that are expelled when a person with the flu coughs or exhales appear to protect the virus when it becomes airborne, regardless of humidity levels, a creative experiment conducted by the University of Pittsburgh and Virginia Tech discovered.
By screening 250 user reviews and comments for a once popular -- but proven inaccurate -- mobile app claiming to change your iPhone into a blood pressure monitor, Johns Hopkins researchers have added to evidence that a high “star rating” doesn’t necessarily reflect medical accuracy or value.
Systematic review of task-related neuroimaging studies found addicted individuals demonstrate increased activity in these networks during drug-related processing but decreases across all other functions
As clinical trials gear up with the aim of attaining the first FDA-approved treatments for mitochondrial disease, a new study reports for the first time what patients and families say would motivate them for or against participating in such research trials.
About 25 percent of Americans experience acute insomnia each year, but about 75 percent of these individuals recover without developing persistent poor sleep or chronic insomnia, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania which will be presented Monday at SLEEP 2018, the 32nd Annual Meeting of the Associated Professional Sleep Societies LLC (APSS).
Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin’s association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function.
Penn Medicine researchers are calling for greater precision in Medicare performance reporting for patients with gastrointestinal bleeding following an evaluation of patients with the condition.
By instructing key immune system cells to accept transplanted insulin-producing islets, researchers have opened a potentially new pathway for treating type 1 diabetes. If the approach is ultimately successful in humans, it could allow type 1 diabetes to be treated without the long-term complications of immune system suppression.
Just beyond the northwest edge of the vast Greenland Ice Sheet, Northwestern University researchers have discovered lake mud that beat tough odds by surviving the last ice age. The mud, and remains of common flies nestled within it, record two interglacial periods in northwest Greenland. Although researchers have long known these two periods — the early Holocene and Last Interglacial — experienced warming in the Arctic due to changes in the Earth’s orbit, the mix of fly species preserved from these times shows that Greenland was even warmer than previously thought.
High school seniors who use heroin commonly use multiple other drugs—and not just opioids, according to a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing.
Haipeng Liu, Ph.D., assistant professor of chemical engineering at Wayne State University, received a Faculty Early Career Development (CAREER) award from the National Science Foundation to fund his research on vaccine adjuvants that can improve the treatment and care of cancer patients.
Those particles that can be in two places at the same time and are not just particles but also waves appear to move in even weirder ways than previously thought. Theoretical physicists at Georgia Tech applied extreme computing power for a week to predict the movements of fermions by including quantum optics, or light-like, ideas in their mathematical, theoretical modeling.
In a study published in the May 21, 2018 issue of the Proceedings of the National Academy of Sciences, a team of researchers – aided with supercomputing resources from the San Diego Supercomputer Center (SDSC) based at UC San Diego – created a dynamic computer simulation to delineate a key biological process that allows the body to repair damaged DNA.
Researchers from the University of California, Irvine School of Medicine, in collaboration with scientists at UCSF and Northwestern University, have profiled human breast epithelial cells, identifying three new distinct epithelial cell populations. The discovery of these cell populations could aid in understanding the origins of breast cancer and lead to improved early cancer detection, a slowing of cancer progression and possibly even cancer prevention.
A new approach pioneered at the University of Pennsylvania’s Abramson Cancer Center may provide a new path towards treating Acute Myeloid Leukemia (AML) with CAR T cells.
Rates of inherited mutations in genes other than BRCA1/2 are twice as high in breast cancer patients who have had a second primary cancer – including, in some cases, different types of breast cancer – compared to patients who have only had a single breast cancer.
A new study shows that people who take drugs that suppress the immune system are less likely to develop Parkinson's disease, which is characterized by difficulty with movement.
Engineers at the University of California San Diego have developed tiny ultrasound-powered robots that can swim through blood, removing harmful bacteria along with the toxins they produce. These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids.
Researchers at the University of Pennsylvania’s Abramson Cancer Center say a patient treated for chronic lymphocytic leukemia (CLL) in 2013 went into remission because of a single CAR T cell and the cells it produced as it multiplied, and has stayed cancer free in the five years since, with CAR T cells still present in his immune system.
Dubbed “T-cell engaging bi-specific antibodies,” these cancer combatants attack malignant cells but leave healthy cells untouched.
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