A study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Cell Biology, details a previously unexplained type of cell death called disulfidptosis that could open the door for novel cancer therapeutic strategies.
Iowa State's Xianglan Bai is leading two, $2-million-plus projects that will study and develop new ways to break down waste plastics and convert them to useful materials. The U.S. Department of Energy is supporting both projects.
Florida State University has been awarded a $72.7 million grant from the National Institutes of Health (NIH) to redesign and improve HIV prevention and care interventions in adolescents and young adults in the United States. Under the grant, which will be dispersed over the course of seven years, FSU will serve as the Scientific Leadership Center (SLC) for the Adolescent Medicine Trials Network for HIV Interventions.
For the more than 6 million Americans living with Alzheimer’s disease, related dementias, or mild cognitive impairment, anxiety is often an accompanying challenge. A Florida State University psychologist has received a five-year, $3.7 million grant from the National Institute on Aging to study intervention techniques that aim to combat anxiety in these groups and improve quality of life.
St. Jude scientists added a small physical structure called an anchor domain to the CAR molecule. The anchor domain connects the CAR to the internal infrastructure of the immune cell. It augments and helps organize the immune synapse
Todd Florin, MD, MSCE, from Ann & Robert H. Lurie Children’s Hospital of Chicago recently was awarded a $5.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) for a multicenter study to derive and broadly validate the first emergency department (ED)-based pediatric community-acquired pneumonia severity (PedCAPS) score. This objective score will help avoid many unnecessary hospitalizations in children at low risk of severe outcomes, while targeting more focused therapies towards the lower proportion of children at highest risk for severe disease.
Pia Pannaraj, MD, MPH, an infectious disease specialist at Children's Hospital Los Angeles, was awarded $4.2 million from the National Institutes of Health to study COVID-19 immunity in children.
Implementing financial coaching for parents of infants in a pediatric primary care setting reduced missed well-child care visit rates by half and significantly improved receipt of vaccinations at a timely age, according to a new community-partnered pilot study led by UCLA researchers.
Rutgers Biomedical and Health Sciences (RBHS) is launching the Herbert and Jacqueline Krieger Klein Alzheimer’s and Dementia Clinical Research and Treatment Center. Based at the Rutgers Brain Health Institute and scheduled to open in fall 2023, the center will offer research expertise from the institute, Rutgers Robert Wood Johnson Medical School, Rutgers New Jersey Medical School and the Rutgers Institute for Health, Health Care Policy and Aging Research as well as facilitate clinical research in Alzheimer’s disease that could result in new medical treatments.
A new study suggests that the presence of academic medical centers within a healthcare market is linked to better outcomes for patients treated at nearby community hospitals.
The University of Oregon is proud to announce Katie McLaughlin, a professor and influential clinical psychologist, has been selected to lead the Portland-based Ballmer Institute for Children’s Behavioral Health.
A University of Maryland School of Medicine (UMSOM) physician-scientist will head a new federally-funded research program to develop and test a whole blood product, storable at room temperature, that can be used to transfuse wounded soldiers in the field within 30 minutes of injury, potentially saving thousands of lives.
Biomedical engineer Yuan Yang has received nearly $2 million in funding from the National Institutes of Health and the American Heart Association to examine the impact of strokes and the movement impairments stroke patients suffer.
Using focused-ultrasound-mediated liquid biopsy in a mouse model released more tau proteins and another biomarker into the blood than without the intervention. This noninvasive method could facilitate diagnosis of neurodegenerative disorders, according to research from Washington University in St. Louis.
Children’s Hospital Los Angeles Awarded $2.5 Million Grant to Address Youth Mental Health Crisis by Training Primary Care Pediatricians in Behavioral and Mental Health.
Using a crowdsourcing framework utilized over the past five years, Juliet Iwelunmor, Ph.D., professor of global health and behavioral science and health education at Saint Louis University’s College for Public Health and Social Justice, is taking what she learned from empowering youth in Nigeria to identify young people in the United States who aim to become the next generation of HIV researchers, leaders and innovators in the field.
A new UC Davis study reveals the interaction between tumor microbiome and the immune system may be the secret to improving outcomes for sarcoma patients.
To help set the record straight about what it’s like to be a woman in orthopedics, Dr. Julianne Muñoz launched a mentorship group for female medical students, residents, fellows, and attendings, called the Female Orthopedists of Miami Mentorship Organization. The program has been so promising that the AAOS earmarked funding for it through the association’s Inspiring Diversity, Equity, and Access (IDEA) grant program.
Inmazeb (REGN-EB3), developed by Regeneron, is a three-antibody cocktail designed to target the Ebola virus glycoprotein. The drug was first approved for clinical use in October 2020, but its exact mechanism of action has remained unclear.
UT Southwestern physician-scientist Hesham Sadek, M.D., Ph.D., has received the prestigious National Institutes of Health (NIH) Outstanding Investigator Award to support his ongoing research into mechanisms behind heart regeneration that could lead to treatments for heart failure.
In an academic-industrial collaboration, Mayo Clinic is assessing in a clinical trial a new radiotracer in pancreatic cancer imaging.
Moffitt Cancer Center, Weill Cornell Medicine and the University of North Carolina School of Medicine have received a $3.5 million, five-year grant from the National Cancer Institute (NCI) to improve screening and preventative treatment of cervical cancer for women living with HIV in low-resource countries.
Sandia National Laboratories, in partnership with Los Alamos and Lawrence Livermore national labs, has awarded a contract to AMD that funds research and development of advanced memory technologies expected to accelerate high-performance simulation and computing applications in support of the nation’s stockpile stewardship mission.
Vinegar flies use pheromones to ensure that they court and mate with members of the same species. As new fly species split off from a common ancestor, but continue to share the same environment, they need a way to rapidly diversify their pheromones to suppress inter-species mating. New research identifies a link between the genetic instructions for the production and perception of sex pheromones.
DePaul University and Rosalind Franklin University of Science and Medicine are funding three faculty research projects that bring together artificial intelligence, biomedical discovery and health care. The competitive grants kickstart research among interdisciplinary teams, which include biologists, computer scientists, a geographer and a physicist.
Early exposure to pesticides can affect health later in life, including negative effects to the nervous and endocrine systems in the body. The SWCPEH has partnered with promotores, or community health workers, from Familias Triunfadoras Inc. to educate the local migrant farmworker community. These underserved communities often have poor access to basic necessities and are most in need of preventative and routine health care.
A Northumbria University physicist has been awarded more than half a million pounds to develop artificial intelligence which will protect the Earth from devastating space storms.
Johns Hopkins Medicine investigators say their research indicates a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant (MDR) strains
monoclonal antibody treatment was found to be safe, well tolerated, and effective in protecting against malaria in a small group of healthy volunteers who were exposed to malaria in a challenge study, according to new research published in The Lancet Infectious Diseases by researchers at the University of Maryland School of Medicine (UMSOM).
UC San Diego and its collaborating partners have been awarded $10 million from the Howard Hughes Medical Institute to leverage the biomedical promise of viruses known as bacteriophages as new therapeutic agents in the fight against the rising crisis of antibiotic-resistant bacterial infections.
Today, the U.S. Department of Energy (DOE) announced $9.1 million in funding for 13 projects in Quantum Information Science (QIS) with relevance to nuclear physics. Nuclear physics research seeks to discover, explore, and understand all forms of nuclear matter that can exist in the universe – from the subatomic structure of nucleons, to exploding stars, to the emergence of the quark-gluon plasma seconds after the Big Bang.
Today, the U.S. Department of Energy (DOE) announced $125 million for basic research on rechargeable batteries to provide foundational knowledge needed to transform and decarbonize our energy system through the development and adoption of cost-effective and clean energy sources. The national, economic, and environmental security challenges will not be met solely by incremental improvements to existing clean energy technologies but instead will require transformational technologies founded on new fundamental knowledge and capabilities developed through basic scientific research.
Researchers in University at Albany’s Center for Behavioral Health Promotion and Applied Research in the School of Education have received funding to undertake a new project aimed at reducing risk for suicide and substance use among students experiencing health disparities. The work aims to hone strategies that could be implemented widely across college campuses.
Investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that a subset of mutations within the overall TMB, termed “persistent mutations,” are less likely to be edited out as cancer evolves, rendering tumors continuously visible to the immune system and predisposing them to respond to immunotherapy.
The Association for Research in Vision and Ophthalmology (ARVO) announced today the 2023 recipients of the Dr. David L. Epstein Award:Since 2016, the Dr. David L. Epstein Award has been given annually to a well-established senior investigator with a documented history of conducting eye and vision research in glaucoma and of mentoring clinician-scientists to independent academic and research careers.
A recent study from Heidi Munger Clary, M.D., M.P.H., associate professor of neurology at Wake Forest University School of Medicine, shows that phobic and agoraphobic symptoms are common and associated with poor quality of life in people with epilepsy.
A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.
The Chan Zuckerberg Initiative awarded a two-year grant for Advancing Imaging Through Collaborative Projects to Kirk Czymmek, PhD, director of the Donald Danforth Plant Science Center’s Advanced Bioimaging Laboratory, Michele Darrow of Rosalind Franklin Institute, and Paul Verkade of the University of Bristol, along with an international team of eight additional scientists.
People with diabetes who experience periods of low blood sugar — a common occurrence in those new to blood sugar management — are more likely to have worsening diabetic eye disease. Now, researchers at Johns Hopkins Medicine say they have linked such low blood sugar levels with a molecular pathway that is turned on in oxygen-starved cells in the eye.
Mount Sinai researchers have been awarded $12 million over five years by the National Institutes of Health to create a center to elucidate novel causes of, and contributing factors to, food allergies and atopic dermatitis. The Systems Biology of Early Atopy (SunBEAm) Analysis and Bioinformatics Center intends to develop a better understanding of allergy development. The center will apply systems biology to identify early-life markers of risk for food allergies and atopic dermatitis (also known as eczema), as well as biological pathways underlying these common conditions, through the profiling and analysis of longitudinal multi-omics data from a multi-center pre-birth cohort of 2,500 children.
IU physicist Adam Szczepaniak is leading a project exploring the physics of exotic hadrons — a largely unexplored group of subatomic particles — under a $1.8 million grant from the U.S. Department of Energy.
Researchers at the University of Miami Miller School of Medicine were awarded a $2.9 million grant by the National Institutes of Health (NIH) to spend the next five years collecting and analyzing the genetic data of more than 3,000 Hispanic individuals, to better understand IBD in that community.
After years of research, an NIH-funded team has developed a wearable cardiac ultrasound imager that can non-invasively capture real-time images of the human heart. The prototype patch, which is about the size of a postage stamp, can be worn during exercise, providing valuable cardiac information when the heart is under stress.
For the first time, researchers at UC San Diego have created an atomic-level computer model of the H1N1 virus that reveals new vulnerabilities, suggesting possible strategies for the design of future vaccines and antivirals against influenza.
Today, the U.S. Department of Energy (DOE) announced $105 million for research in biopreparedness. This funding, provided by the Office of Science, will support fundamental research to accelerate breakthroughs in support of the Biopreparedness Research Virtual Environment (BRaVE) initiative.
University of Maryland School of Medicine’s researchers have discovered that a certain type of cell that sits on top of the brain’s smallest blood vessels senses when their brain region needs energy. When glucose levels are low, these cells signal blood vessels to dilate, increasing the blood flow regionally and allowing more energy to fuel that part of the brain.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.
Nationwide study shows integrated health systems yield marginal increases in quality of care with higher costs for medical services, compared with care delivered by independent hospitals and physician practices. Proponents of health system mergers have argued that consolidation brings higher value care.
Millions of New Yorkers live in “transit deserts” – areas in which public transportation is not easily accessed – but a major grant from New York State means Dollaride, in collaboration with Tandon’s C2SMART Center (the Connected Cities for Smart Mobility Toward Accessible and Resilient Transportation), will help fill that gap with environmentally-friendly electric vehicles.
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