Drug-resistant bacteria have dominated news headlines and the attention of public health experts, but a study by experts at the Johns Hopkins Children’s Center and the Duke Clinical Research Institute shows that nonresistant bacterial infections occur far more often and can take just as great a toll on newborns as their drug-resistant cousins.
The WHO report, published in the New England Journal of Medicine, provides the first results of a long-term study on male Ebola survivors in Sierra Leone.
A joint study by UT Southwestern Medical Center and Parkland Health & Hospital System investigators found that a multicomponent outreach program increased completion of the three-dose human papillomavirus (HPV) vaccination series that reduces the risk of cervical cancer caused by the virus.
To help stop the spread of antibiotic resistance, UC San Francisco scientists are urging hospitals around the country to stop buying meat from animals that were given antibiotics for growth promotion.
Animal science researchers at Iowa State University have identified a pair of genetic mutations that cause immune deficiencies in pigs that make them uniquely good models for testing potential medical therapies for people. The work advances previous ISU research on pigs with severe combined immunodeficiency.
The most severe strep infections are often the work of one strain known as M1T1, named for the type of tentacle-like M protein projecting from the bacterium’s surface. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have uncovered a new way M1 contributes to strep virulence — the protein’s ability to hold off antimicrobial peptides. The study is published October 14 by Cell Host & Microbe.
Scientists at the Tulane National Primate Research Center are leading efforts to find a new vaccine for tuberculosis, one of the world’s deadliest diseases.
A study led by Indiana University biologist Patricia Foster and colleagues has found that forces in the external environment and oxidation are the greatest threats to an organism’s ability to repair damage to its own DNA.
Paul J. Thuluvath, M.D., Chief, Division of Gastroenterology at Mercy Medical Center, has authored the new health book, Hepatitis C: A Complete Guide for Patients and Families, which became available to the public earlier this month.
University of Texas at El Paso (UTEP) researchers have patented a low-cost printer that helps HIV patients living in low-resource settings track the health of their cells.
Drug-resistant E. coli infections are on the rise in community hospitals, where more than half of U.S. patients receive their health care, according to a new study from Duke Medicine.
In a study involving 2,400 men who have sex with men who were also enrolled in the Multicenter AIDS Cohort Study, researchers report that men with HIV who were treated effectively with HIV therapy — defined as no detectable HIV virus in the blood — were the least likely (80 percent less likely) to get infected with HBV over a median follow-up of approximately 9.5 years
Get your flu shot in October for best shot at protection and here's why, says Jorge Parada, MD, infectious disease, Loyola University Health System. Parada explains how the flu serum is formulated and why 2014 was a bad year for the flu.
Researchers found that flu immunizations with four times the strength of standard flu shots significantly reduced the risk of being hospitalized during the influenza season. The group that received the high dose vaccine had a 19.7 percent hospital admission rate versus 20.9 percent in admission for those who received the standard dose vaccine. The findings were presented as a late breaking research presentation on Oct. 10 at the Infectious Diseases Society of America meeting in San Diego.
New research from Penn Medicine infection control specialists found that ultraviolet (UV) robots helped reduce the rates transmission of the common bacterial infection known as Clostridium difficile among cancer inpatients – mostly blood cancer patients, a group more vulnerable to hospital-acquired infections – by 25 percent. The interventions also saved about $150,000 in annual direct medical costs.
Moffitt Cancer Center researchers have developed a novel mathematical method inspired by Darwinian evolution to use current antibiotics to eliminate or reduce the development of antibiotic-resistant bacteria.
The naturally occurring bacteria on a frog’s skin could be the most important tool for helping the animal fight off a deadly skin disease, according to an experiment conducted by Virginia Tech researchers.
In a hospital, what you can’t see could hurt you. Healthcare facilities continue to battle drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA) that loiter on surfaces even after patient rooms have been cleaned and can cause new, sometimes-deadly infections. But a new study from Duke Medicine has found that using a combination of chemicals and UV light to clean patient rooms cut transmission of four major superbugs by a cumulative 30 percent among a specific group of patients -- those who stay overnight in a room where someone with a known positive culture or infection of a drug-resistant organism had previously been treated.
Research from Indiana University has found that sexual activity triggers physiological changes in the body that increase a woman's chances of getting pregnant, even outside the window of ovulation.
Researchers at the University of California, San Diego School of Medicine say that hepatic fibrosis, which involves scarring of the liver that can result in dysfunction and, in severe cases, cirrhosis and cancer, may be as much a consequence of genetics as environmental factors.
Clinical use of next generation sequencing (NGS) was implemented early in cancers and inherited diseases; now, its technology and applications are being applied to infectious diseases.
Stroke is very rare in children, but colds, flu and other minor infections may temporarily increase stroke risk in children, according to a study published in the September 30, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found routine childhood vaccines may decrease the risk of stroke.
The crude annual incidence rates for syphilis among U.S. service members rose 49.1 percent over a health surveillance period from 2010 to 2014, according to a new analysis published in the September issue of the Medical Surveillance Monthly Report from the Armed Forces Health Surveillance Center (AFHSC).
A 20-million-year-old flea preserved in amber harbors the likely ancestor of bacteria that caused one of the world’s deadliest plagues.
A new test detects virtually any virus that infects people and animals, according to research at Washington University School of Medicine in St. Louis, where the technology was developed.
Scientists at Duke Medicine are using transparent fish to watch in real time as Cryptococcal meningitis takes over the brain. The resulting images are worthy of a sci-fi movie teaser, but could be valuable in disrupting the real, crippling brain infection that kills more than 600,000 people worldwide each year.
UCSF-led scientists completed a proof-of-principle study on a real-time blood test based on DNA sequencing that can be used to rapidly diagnose Ebola and other acute infections.
A unique molecule developed at Duke Medicine, the University of North Carolina at Chapel Hill and MacroGenics, Inc., is able to bind HIV-infected cells to the immune system’s killer T cells. It could become a key part of a shock-and-kill strategy being developed in the hope of one day clearing HIV infection.
A study of influenza infection in animals broadens understanding of the immune response to flu virus, showing that the process is more dynamic than usually described. The findings may offer key insights for developing better vaccines.
There is little doubt that the Human Immunodeficiency Virus, or HIV, is devastating. More than 1.2 million people in the United States are living with HIV and more than 47,000 people are diagnosed annually. Now, University of Missouri researchers have made a discovery in how specialized proteins can inhibit the virus, opening the door for progress in the fight against HIV and for the production of advanced therapeutics to combat the disease.
Researchers have discovered how a tiny viral protein enables the infection of a complex plant, and the finding could lead to understanding viral diseases in other plants, animals and humans, according to a team of Texas A&M AgriLife Research biochemists.
David Kimberlin, M.D., is the vice chair of Pediatrics, co-director of the Division of Pediatric Infectious Diseases at UAB and a physician at Children’s of Alabama. He is the editor of the American Academy of Pediatrics’ Red Book, which establishes which vaccines should be given, when and to whom. He is also the father of three children.
Models suggest that when social isolation and coinfection occur together, diseases can spread faster and further than with either effect alone.
Every year at this time, we hear it's time to get the flu shot. After last year's vaccine missed the mark, how does the Center for Disease Control regain the public's confidence that their predictions will hold up this year? With the facts.
UAB researchers have discovered a novel mechanism for one 1918 flu virus protein that may help explain the virulence of that unusually deadly pandemic. That outbreak killed 50 million to 100 million people.
When an older person gets hospitalized for pneumonia, where’s the best place to care for them? New research findings about deaths and health care costs in such patients fly in the face of conventional wisdom – and could change where doctors decide to treat them.
A deadly parasite that causes Chagas disease is widespread in a common Texas insect, according to a new study by University of Texas at El Paso (UTEP) researchers. The finding suggests that the risk of Texans contracting the disease may be higher than previously thought.
Children’s Hospital Los Angeles has added four Xenex Germ-Zapping Robots to its team. Each uses UV-C light to disinfect rooms and destroy pathogens, including Clostridium difficile, norovirus and MRSA.
Researchers have silenced genes within human cells to induce immunity to the parasite E. histolytica, demonstrating the effectiveness of a new approach to protecting people from infectious diseases.
The authors monitored the social and foraging behaviors of wild flocks of house finches, a common backyard songbird, and the spread of a naturally-occurring bird disease called Mycoplasmal conjunctivitis, which is similar to "pink eye" in humans but cannot be contracted by humans.
Reports of a super strain of head lice have many parents concerned as kids head back to the classrooms for the new school year. The dreaded “lice letter” that comes home in backpacks when lice is found in a classroom is causing even greater anxiety this year, as the bugs are becoming more resistant to over-the-counter shampoos and medications. A lice infestation is about as common as a cold, but trying to rid your life of them is even more of a head-scratcher than the disgusting bugs themselves.
Bacteria aren’t the only nonhuman invaders to colonize the gut shortly after a baby’s birth. Viruses also set up house there, according to new research at Washington University School of Medicine in St. Louis. The study is one of the first surveys of viruses that reside in the intestine, providing a first look at a healthy gut virome.
Three antibiotics that, individually, are not effective against a drug-resistant staph infection can kill the deadly pathogen when combined as a trio, according to researchers at Washington University School of Medicine in St. Louis. They have killed the bug — methicillin-resistant Staphylococcus aureus (MRSA) — in test tubes and laboratory mice, and believe the same strategy may work in people.
Virginia Tech researchers have discovered a new group of antibiotics that may provide relief to some of the more than 2 million people in the United States affected by antibiotic resistance.
Researchers at NYU have conducted a systematic review and meta-analysis of studies characterizing the incidence of the sexual transmission of HCV among HIV-positive MSM. The high reinfection rates and the attributable risk analysis suggest the existence of a subset of HIV-positive MSM with recurring sexual exposure to HCV. Approaches to HCV control in this population will need to consider the changing epidemiology of HCV infection in MSM.
An emerging class of drugs called Smac mimetics may lead to a safe and effective treatment to eradicate HIV.
New research led by NYU Langone Medical Center has uncovered why a particular strain of Staphylococcus aureus -- known as HA-MRSA -- becomes more deadly than other variations. These new findings open up possible new pathways to vaccine development against this bacterium, which the Centers for Disease Control and Preventions says accounts for over 10,000 deaths annually, mostly among hospital patients.
A new University of Kentucky study in the journal mBio shows that tissue cysts of the parasite Toxoplasma gondii, long thought to be dormant, are quite active.
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