The rate of overdose deaths among U.S. teenagers nearly doubled in 2020, the first year of the COVID pandemic, and rose another 20% in the first half of 2021 compared with the 10 years before the pandemic, even as drug use remained generally stable during the same period.
University of Maryland School of Medicine’s Institute of Human Virology contributes to Global Virus Network studies suggesting that the oral polio vaccine can protect people in developing nations that do not yet have access to COVID vaccines
Findings from Study Led by Susan G. Komen Scholars Published in JAMA Oncology
Scientists analyzed ultrasounds for a wide range of birth defects from life-long and severe to short-term and mild
The first results of research led by the University of Washington into handgun carrying by young people growing up in rural areas has found six distinct patterns for when and how often these individuals carry a handgun.
African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.
The largest survey to date shows that rapid information sharing, multi-disciplinary teams and novel communication methods enabled remarkable consistency of care across U.S. hospitals.
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New research from the Case Western Reserve University (CWRU) School of Medicine suggests that the children younger than age 5 who are infected with the COVID-19 Omicron variant have less risk of severe health outcomes than those infected with the Delta variant.
Nearly half of all older adults now die with a diagnosis of dementia listed on their medical record, up 36% from two decades ago, a new study shows. But that sharp rise may have more to do with better public awareness, more detailed medical records and Medicare billing practices than an actual rise in the condition, the researchers say.
While it's estimated that 1 in 3 Americans will develop a substance use disorder in their lifetime, experts know little about the long-term outcomes for people with substance use disorder symptoms from adolescence through adulthood.
Scientists have developed a novel measure of delirium severity that could help improve patient-centered care for delirium.
A study published in the Journal of the American Medical Association Surgery is the first in North America to demonstrate that living-donor liver transplant is a viable option for patients who have systemically controlled colorectal cancer and liver tumors that cannot be surgically removed.
In a new study from Vanderbilt University Medical Center, 10-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.
Half of all women experience a false positive mammogram after 10 years of annual breast cancer screening with 3D mammography, a UC Davis-led study estimates. This risk was lower for women who had mammograms every other year. 3D screening showed slightly lower false positive results than standard mammography.
Vaccination against COVID-19 during pregnancy is not associated with a higher risk of pregnancy complications, according to a large-scale registry study from Karolinska Institutet in Sweden and the Norwegian Institute of Public Health published in the journal JAMA.
Researchers at the George Washington University published findings from the world’s largest cohort study showing that hospitalized patients with moderate COVID-19 who were given aspirin early on in their treatment had a lower risk of dying compared to patients who were not given aspirin.
Despite strong evidence that medication is the most effective treatment for opioid use disorder (OUD), adolescents and most adults who might benefit from OUD treatment report no medication use, according to a study by researchers at the Rutgers School of Public Health and Columbia University Mailman School of Public Health.
Researchers with UTHealth Houston outline five steps for clinicians to assess their electronic health records (EHR) using the SAFER guidelines. The study was published in the Journal of the American Medical Association JAMA.
Efforts to determine the actual size and makeup of the abortion provider workforce in the U.S. often rely on surveys that are limited in scope or else focus solely on abortion facilities. To get more comprehensive pictures of the abortion provider workforce, researchers at the George Washington University combed through a national medical claims data set to examine the workforce providing abortion care and management of pregnancy loss.
Researchers at Washington University School of Medicine in St. Louis have found that people with severe alcohol use disorder miss more than double the number of workdays missed by individuals without alcohol use disorder. The total number of missed workdays due to alcohol use disorder was 232 million.
Hepatitis screening rates climbed to 80 percent for patients whose doctors didn’t need to opt in to order a screening
In a JAMA perspective piece, leading infectious disease researchers call for a coordinated response to HIV and COVID-19 globally, building on the successes of key donor programs such as the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program and Global Fund to Fight AIDS, TB and Malaria (GFATM).
Keck Medicine of USC study shows that the incidence rate of metastatic prostate cancer rose as much as 43% in men 75 and older and 41% in men 45-74 after routine prostate cancer screenings were no longer recommended
People who kill themselves with a firearm are more likely to talk about suicide a month before ending their lives than ask for help and seek mental health treatment, according to a study by the New Jersey Gun Violence Center at Rutgers University.
The study, led by Moffitt Cancer Center, followed 515 patients with varying cancers. The goal was to evaluate if patients had an immune response to the Moderna mRNA-1273 vaccine and if that response differed by diagnosis and treatment.
Malignant Pleural Mesothelioma (MPM) is an aggressive cancer mostly related to asbestos exposure whose incidence is constantly rising, especially in low-income countries.
They’re old enough to qualify for Medicare, and their incomes are low enough to qualify them for Medicaid. And when they have surgery to remove a cancerous tumor, a new study finds, they suffer more complications and incur higher costs than patients with Medicare alone, even at top hospitals.
Have you ever felt uncomfortable when asked about depression or any other sensitive personal issue when checking in for a medical visit?
Older adults who report being under severe financial strain were substantially more likely to die within six months of having a heart attack compared to those with moderate or no financial strain, according to a new study led by University of Maryland School of Medicine (UMSOM) researchers.
A study on smokers who drink heavily finds that a combination treatment of the drug varenicline and nicotine replacement therapy is more effective for smoking cessation, and that efforts to quit smoking can indirectly lead to reduced drinking rates.
In 2010, scientists discovered that African Americans who are born with certain variants of a gene called apolipoprotein L1 (APOL1) have a higher-than-average risk for experiencing chronic kidney disease (CKD). Now, in a new study of African Americans with hypertension, researchers at the Icahn School of Medicine at Mount Sinai find that a community-based approach to reporting APOL1 genetic test results back to individuals may have beneficial effects.
Results from a new clinical trial demonstrate that an eight-week mindfulness-based therapy—Mindfulness-Oriented Recovery Enhancement (MORE)—decreased opioid use and misuse while reducing chronic pain symptoms, with effects lasting as long as nine months.
In 2020, the first year of the COVID-19 pandemic, the rate of drug overdose deaths among Black Americans surpassed that of whites for the first time since 1999 — a sharp reversal of the situation a decade earlier, when rates were twice as high for whites as for Blacks.
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Approximately 23,700 children in the U.S. undergo invasive mechanical ventilation for acute respiratory failure annually. Although most survive, little is known if they have worse long-term neurocognitive function than children who do not undergo such procedures. There are concerns about neurotoxic effects of critical illness and its treatment on the developing brain. Therefore, infants and young children may be uniquely susceptible to adverse neurocognitive outcomes after invasive mechanical ventilation.
In early 2021, researchers at Johns Hopkins Medicine and NORC at the University of Chicago showed that the Agency for Healthcare Research and Quality Safety Program for Improving Antibiotic Use successfully helped more than 400 U.S. hospitals ensure that patients only received antibiotics when needed, and then, only in the correct amounts and for the prescribed dosage period.
Analyzing breast-cancer tumors with artificial intelligence has the potential to improve healthcare efficiency and outcomes, but doctors should proceed cautiously, according to a new editorial in JAMA Health Forum co-written by Dr. Joann G. Elmore, a researcher at the UCLA Jonsson Comprehensive Cancer Center.
Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis. The new findings were published in JAMA Cardiology.
A review of available data suggests that there was not a significant rise in child abuse related to COVID-19. Robert Sege of Tufts University School of Medicine and Tufts Medical explains the "missing epidemic of child abuse" in a recent JAMA Pediatrics viewpoint.
During periods of extreme heat, clinicians should expect to see an increase in patients requiring mental health services, according to a new study led by Boston University School of Public Health researchers.
Patients treated for Merkel cell carcinoma face a five-year recurrence rate of 40%—markedly higher than recurrence rates for other skin cancers, according to new research in JAMA Dermatology. As well, 95% of recurrences happened in the first 3 years, suggesting surveillance should be focused in that span.
Falls are a leading cause of hospitalization and institutionalization for older adults in the U.S. and fall prevention efforts are an important part of geriatric education and health.
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A new study that monitors patients who received “on-pump” or “off-pump” coronary artery bypass grafting (CABG) over a 10-year period reveals that outcomes between the two forms of heart bypass surgery are not much different. The findings are published in JAMA Surgery.
Annual MRI screenings starting at ages 30 to 35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes (ATM, CHEK2, PALB2), according to a newly published comparative modeling analysis. The findings will be published Feb. 17 in JAMA Oncology.
Before lifting mask mandates in elementary schools in the U.S., local COVID-19 case rates should be far below current rates to avoid the risk of increased transmission among students, staff, and families, according to a study led by researchers at Harvard T.H. Chan School of Public Health and Massachusetts General Hospital (MGH).
A new study from Ann & Robert H. Lurie Children’s Hospital of Chicago found that children from less resourced neighborhoods were at increased odds of presenting with complicated appendicitis, an indicator of delayed access to surgical care. This is the first pediatric study to link many neighborhood-level factors that influence health – such as quality of schools, housing, safety, and economic opportunity – to timely surgical care access.
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Patients undergoing bladder removal surgery, known as cystectomy, need from three to six months to recover regardless of whether they have robot-assisted radical cystectomy or the traditional open approach, according to a multicenter study led by Miller School investigators and published in JAMA Network Open.
UC San Diego Health researchers surveyed and compared early- and late-stage breast and colorectal cancer diagnoses in patients in pre-pandemic 2019 and in 2020, the first full year of the COVID-19 pandemic, discovering fewer of the former and more of the latter as patients delayed care.
African children and adolescents hospitalized with COVID-19 experience much higher mortality rates than Europeans or North Americans, according to a study conducted by the Institute of Human Virology at the University of Maryland School of Medicine and the Institute of Human Virology Nigeria.
A new study at Children’s Hospital Los Angeles independently verified the value of a system that assesses hepatoblastoma risk in children. Hepatoblastoma is a rare childhood liver cancer, usually seen within the first three years of a child’s life with 50 to 70 cases occurring in the U.S. each year.
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