Long-awaited outcomes data of transcatheter edge-to-edge procedures to repair patients’ leaky mitral valves revealed the minimally invasive procedure to be safe and effective in nearly 90% of patients, according to Cedars-Sinai physician-scientists.
Researchers at the University of Warwick and The James Cook University Hospital, Middlesbrough have led a clinical trial, funded by the National Institute for Health and Care Research (NIHR), on a new treatment which can help people stop needing to use opioid painkillers to manage chronic pain.
A new study led by researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, has found that mucus plugs were also associated with greater mortality.
Investigators from the Smidt Heart Institute at Cedars-Sinai found that women who experience an adverse pregnancy outcome—such as gestational hypertension, preeclampsia or preterm birth—have a higher risk of developing stroke in their lifetime, and at a younger age.
The commonly used U.S version of the Fracture Risk Assessment Tool (FRAX) should not be routinely used to select younger postmenopausal women for bone mineral density testing. But the Osteoporosis Self-Assessment Tool (OST) is excellent at identifying women with osteoporosis-level bone mineral density, which is the goal of these screenings, while FRAX is not.
HealthPartners Institute researchers have published new data in JAMA Network Open that shows monovalent COVID-19 booster vaccinations administered in early pregnancy (before 20 weeks’ gestation) were not associated with miscarriage. The research adds to the growing understanding about the safety of COVID-19 booster vaccinations among people who are pregnant.
Rutgers study shows higher number of caregivers prescribing buprenorphine
In this case-control surveillance study of more than 100,000 pregnancies, COVID-19 booster vaccination in pregnancy was not associated with spontaneous abortion. These findings support the safety of recommendations for COVID-19 booster vaccination, including in pregnant populations.
Surviving a stroke can bring many long-term effects – including a much higher risk of dementia. But a study suggests that blood sugar may play a key role in that risk.
A new study reveals a staggering disparity in life expectancy between Black Americans and their white counterparts between 1999 and 2020. In an analysis of U.S. data, a Yale-led team of researchers found 1.63 million excess deaths in the Black population compared with white Americans, representing more than 80 million excess years of potential life lost.
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According to two data sources, in 2018, the economic burden of health inequities for racial and ethnic minority populations (American Indian and Alaska Native, Asian, Black, Latino, and Native Hawaiian and Other Pacific Islander populations) was $421 billion or $451 billion and the economic burden of health inequities for adults without a 4-year college degree was $940 billion or $978 billion.
For families facing the end of life of a loved one with pediatric cancer, robust quality measures to benchmark what parents value most in their child’s medical care do not currently exist. A new study helps identify what parents prioritize for their children with advanced cancer, including alleviating the child’s symptoms and honoring the family’s goals and wishes.
Seemingly healthy people whose blood contained antibodies associated with a condition called antiphospholipid syndrome (APS) were significantly more likely to experience a cardiovascular event such as a heart attack or stroke than those without, a study led by UT Southwestern Medical Center scientists shows
In a recently published commentary, UK HealthCare physicians call for standard-of-care treatment for opioid use disorder (OUD) among patients who are incarcerated.
The anti-dementia medication lecanemab and its ancillary costs could add $2 billion to $5 billion in annual Medicare spending if the Centers for Medicare and Medicaid Services (CMS) revise their coverage decision. Currently, the medication is covered only for patients who are enrolled in clinical trials.
In a study publishing May 10 in JAMA Cardiology, senior author and UCSF cardiologist Geoff Tison, MD, MPH, and first author Robert Avram, MD, of the Montreal Heart Institute, set out to determine whether deep neural networks (DNNs), a category of AI algorithm, could be used to predict cardiac pump (contractile) function from standard angiogram videos. They developed and tested a DNN called CathEF, to estimate LVEF from coronary angiograms of the left side of the heart.
Study following Chicagoans over a 25-year period suggests over half of the city’s Black and Hispanic population, and a quarter of its White population, have seen a shooting by age 40.
In this study, patients using medical cannabis reported improvements in health-related quality of life, which were mostly sustained over time. Adverse events were rarely serious but common, highlighting the need for caution with prescribing medical cannabis.
Repeated mammograms contain data on changes in breast density over time that could help identify women at high risk of breast cancer and even reveal which breast is likely to be affected, according to a study by researchers at Washington University School of Medicine in St. Louis.
Black and Hispanic adults at risk of developing cardiovascular disease are less likely to take statin drugs than white adults with the same risk factors, UT Southwestern Medical Center researchers reported in JAMA Cardiology.
Contrary to popular belief, firearm deaths in the United States are statistically more likely in small towns, not major cities, according to new research.
After a stroke, physical activity can be pivotal to successful recovery. People who spend four hours a week exercising after their stroke achieve better functional recovery within six months than those who do not, a University of Gothenburg study shows.
A sharp increase in the price of the gout drug colchicine, the result of an unusual FDA policy, led to lower use and poorer disease control. The findings have implications for other drugs, whose price could be similarly affected by government policies and manufacturer decisions.
People who perceived that they had cognitive difficulties such as memory problems during COVID were more likely to have lingering physical manifestations of the disease than people who did not report cognitive issues.
Parents, as well as pediatric healthcare clinicians, may want to protect young people from difficult new about their advanced heart disease but many adolescents and young adults prefer being engaged with medical decision-making.
Upon an arrival to the emergency department for abdominal pain of unknown cause, most non-pregnant adult patients receive a CT scan with IV contrast to diagnose the source of the pain. However, IV contrast can be a risk in patients with severe kidney disease or at risk for an allergic reaction from the dye. When scans are performed without IV contrast, though, they are usually less accurate, which can lead to misdiagnosis.
Acute radiation dermatitis (ARD)—characterized by red, sore, itchy or peeling skin—affects up to 95% of people undergoing radiation treatment for cancer. Severe cases can cause significant swelling and painful skin ulcers that can severely impair quality of life, yet little is known about why this condition occurs and no standardized treatments for preventing severe ARD have been widely adapted.
Left ventricular conduction disease occurs when there is an electrical blockage of the heart’s normal electrical conduction system. Treatment to lessen its effects involves implanting a permanent pacemaker, but there have been no proven preventive strategies for this condition. In a study publishing May 3, 2023 in JAMA Cardiology, first author Emilie Frimodt-Møller, MD, and senior author Gregory Marcus, MD, MAS, found that intensive BP control is associated with lower risk of left ventricular conduction disease, indicating left ventricular conduction disease may be preventable.
A new study found a declining proportion of DATA-waivered clinicians prescribed any buprenorphine between 2017 and 2021. While the number of waivered clinicians increased significantly during the five-year window, only one out of three prescribed any buprenorphine as of May 2021. Furthermore, the majority of prescriptions were written by clinicians who specialize in treating opioid use disorder. The new study was published as a research letter in JAMA.
Applying machine learning models, a type of AI, to data collected passively from wearable devices can identify a patient’s degree of resilience and well-being, according to investigators at the Icahn School of Medicine at Mount Sinai in New York. The findings, reported in the May 2nd issue of JAMIA Open, support wearable devices, such as the Apple Watch®, as a way to monitor and assess psychological states remotely without requiring the completion of mental health questionnaires.
Internet search trends may immediately capture how society seeks information related to reproductive health care, according to new research from Indiana University researchers.
Research from Cedars-Sinai Cancer detailing the largest examination to date of prostate cancer in transgender women, as well as treatment options that improve outcomes in patients with recurrent prostate cancer, will be presented during the American Urological Association (AUA) annual meeting April 28-May 1 in Chicago.
A study of ChatGPT found the artificial intelligence tool answered less than half of the test questions correctly from a study resource commonly used by physicians when preparing for board certification in ophthalmology.
The Perceptions of Research Trustworthiness (PoRT), described in an original investigation published in JAMA Network Open, is a groundbreaking tool designed as an on-going gauge of perception of trust and distrust in biomedical research, said team leader Consuelo H. Wilkins, MD, MSCI, Senior Vice President and senior associate dean for Health Equity and Inclusive Excellence and professor of Medicine at Vanderbilt University Medical Center (VUMC).
As a result of demographic change, the proportion of older oncology patients is rising sharply. Compared to younger patients, cancer treatment is highly individualised due to more frequent and sometimes severe comorbidities, increasing age-related infirmities and reduced physical fitness.
First-ever randomized clinical trial linked to registry data from ACS NSQIP published in JAMA.
Treating opioid addiction should be much easier now than it was a few years ago, thanks to pandemic-era rule changes that aim to improve access to buprenorphine, a medicine proven to help in recovery. But a new study shows prescriptions and adherence rates have remained flat.
A new study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with Dell Medical School, University of Minnesota, and the Vanderbilt University Medical Center, using a national data sample from the National Institutes of Health All of Us Research Program, revealed that a small but statistically significant proportion of patients with cancer, especially younger and lower-income minorities, disproportionately reported delaying care because of patient/clinician racial, gender and cultural differences.
Researchers have identified a strong association between prevalence of prescription stimulant therapy for attention-deficit/hyperactivity disorder (ADHD) and rates of prescription stimulant misuse (taken in a way other than as directed by a clinician) by students in middle and high schools.
Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit. A new study led by researchers at Brigham and Women’s Hospital, a founding member of Mass General Brigham, used public Medicare data to identify the 50 highest-selling brand-name drugs in 2020.
Their experiment shows that children will eat significantly more fruits and vegetables if they on average stay at the table for only ten minutes more – 30 minutes in total. On average, they ate about 100 grams more fruits and vegetables.
U.S. middle and high schools with the most students taking prescription stimulants to treat ADHD also had, overall, the highest percentage of students who misused prescription stimulants within the past year.
New research from Boston Medical Center concluded that offering medications to treat opioid addiction in jails and prisons leads to a decrease in overdose deaths. Published in JAMA Network Open, the study also found that treating opioid addiction during incarceration is cost-effective in terms of healthcare costs, incarceration costs, and deaths avoided.
The first study to examine evaluation scores for professionalism and interpersonal communication skills among physicians-in-training and what happens afterward as these doctors begin their practice was reported April 11 in . The study tracked 9,340 early-career physicians from across the country.
A study, based on reported cases of new cancer diagnosis to the National Cancer Database (NCDB), estimates roughly 200,000 people with cancer cases weren’t diagnosed or treated at Commission on Cancer-accredited facilities at the onset of the pandemic in 2020, around the same time that triage guidelines recommended delays in cancer-related care.
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