Curated News:

Promising intracellular protein-based therapeutics have been of limited use due to the difficulty of delivery into diseased cells. Now bioengineers have developed nanoparticles that can deliver these therapeutics to their targets—avoiding degradation and toxic interactions with healthy tissues.

Channels: All Journal News, Cancer, Drugs and Drug Abuse, Engineering, Nanotechnology, Pharmaceuticals, National Cancer Institute (NCI), National Eye Institute (NEI), Grant Funded News,

Keywords: nanoparticle drug delivery, CRISPR, drug delivery vehicle, Brain Cancer, protein therapeutics, nano assembly, targeted therapeutics

With $9.7 million in funding from the National Eye Institute, researchers at the University of Illinois at Chicago will study the impact of chronic eye disease among Latinos.

Channels: All Journal News, Race and Ethnicity, Vision, Grant Funded News, National Eye Institute (NEI), National Institutes of Health (NIH), South America News,

Keywords: Eye Disease, Glaucoma, Diabetic Retinopathy, Macular Degeneration, Research, health disparites

In a recent study using mice, lab-grown human retinal cells and patient samples, Johns Hopkins Medicine scientists say they found evidence of a new pathway that may contribute to degeneration of the light sensitive tissue at the back of the eye. The findings, they conclude, bring scientists a step closer to developing new drugs for a central vision-destroying complication of diabetes that affects an estimated 750,000 Americans.

Channels: All Journal News, Diabetes, Pharmaceuticals, Vision, National Eye Institute (NEI), Grant Funded News, NIH Eye Inst Grants,

Keywords: Diabetes, Diabetic Macular Edema, angiopoietin, Akrit Sodhi, Retina

Researchers at the National Eye Institute used artificial intelligence to evaluate stem cell-derived “patches” of retinal pigment epithelium tissue for implanting into the eyes of patients with age-related macular degeneration, a leading cause of blindness.

Channels: All Journal News, Vision, National Institutes of Health (NIH), National Eye Institute (NEI),

Results from a clinical trial funded by the National Eye Institute (NEI) show that while vision therapy can successfully treat convergence insufficiency (CI) in children, it fails to improve their reading test scores.

Channels: All Journal News, Children's Health, Speech & Language, Vision, National Eye Institute (NEI), Embargoed Feed - hidden,

Keywords: Optometry, Children, Convergence Insufficiency

Researchers at the University of Illinois at Chicago are the first to identify the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid. They are also the first to demonstrate that patients with dry eye disease experienced reduced signs and symptoms of the condition in response to a new eye drop treatment -- made from pooled human antibodies -- that targets ACPAs.

Channels: Vision, National Eye Institute (NEI), All Journal News,

Keywords: Dry eye disease, cornea disease, anticitrullinated protein autoantibodies

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis

Channels: All Journal News, Clinical Trials, Pharmaceuticals, Vision, National Institutes of Health (NIH), National Eye Institute (NEI), Embargoed Feed - hidden,

Keywords: Uveitis, Antimetabolites, Ophthalmology, Clinical Trial

Anyone who has ever sensed that a person is sick simply by looking at their face has experienced the wealth of information conveyed by face color. A new study by the National Eye Institute (NEI), part of the National Institutes of Health, provides evidence that the human brain’s visual system is especially sensitive to the color of faces compared to the colors of other objects or things. Study results were published today in Nature Communications.

Channels: All Journal News, Vision, Nature (journal), National Institutes of Health (NIH), National Eye Institute (NEI),

Children can keep full visual perception – the ability to process and understand visual information – after brain surgery for severe epilepsy, according to a study funded by the National Eye Institute (NEI), part of the National Institutes of Health. A new report by Carnegie Mellon University, Pittsburgh, researchers from a study of children who had undergone epilepsy surgery suggests that the lasting effects on visual perception can be minimal, even among children who lost tissue in the brain’s visual centers.

Channels: Children's Health, Epilepsy, Neuro, Vision, National Institutes of Health (NIH), National Eye Institute (NEI), Embargoed Feed - hidden, All Journal News,

Keywords: Epilepsy, plasticity in brain, Visual Perception, Neuroscience

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.The trial compared eye drops containing a biosynthetic form of an enzyme called DNase with eye drops without the enzyme.

Channels: Clinical Trials, Vision, National Eye Institute (NEI), All Journal News,

Keywords: dry eye, Clinical Trials