Curated News: National Eye Institute (NEI)

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Newswise: NIH researchers discover tooth-enamel protein in eyes with dry AMD
Released: 13-Mar-2020 12:45 PM EDT
NIH researchers discover tooth-enamel protein in eyes with dry AMD
NIH, National Eye Institute (NEI)

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a study from researchers at the National Eye Institute (NEI).

Newswise: ‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye
Released: 9-Mar-2020 9:00 AM EDT
‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye
Johns Hopkins Medicine

Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases.

Newswise: AI may help spot newborns at risk for most severe form of blinding disease
Released: 4-Mar-2020 12:05 PM EST
AI may help spot newborns at risk for most severe form of blinding disease
NIH, National Eye Institute (NEI)

An artificial intelligence (AI) device that has been fast-tracked for approval by the Food and Drug Administration may help identify newborns at risk for aggressive posterior retinopathy of prematurity (AP-ROP). AP-ROP is the most severe form of ROP and can be difficult to diagnose in time to save vision.

Newswise: Tiny containers transport targeted treatments
Released: 27-Jan-2020 12:35 PM EST
Tiny containers transport targeted treatments
National Institute of Biomedical Imaging and Bioengineering

Promising intracellular protein-based therapeutics have been of limited use due to the difficulty of delivery into diseased cells. Now bioengineers have developed nanoparticles that can deliver these therapeutics to their targets—avoiding degradation and toxic interactions with healthy tissues.

Released: 10-Dec-2019 2:10 PM EST
'Ojos' study to examine eye disease in Latino communities
University of Illinois at Chicago

With $9.7 million in funding from the National Eye Institute, researchers at the University of Illinois at Chicago will study the impact of chronic eye disease among Latinos.

Newswise: Helper Protein Worsens Diabetic Eye Disease
Released: 27-Nov-2019 8:00 AM EST
Helper Protein Worsens Diabetic Eye Disease
Johns Hopkins Medicine

In a recent study using mice, lab-grown human retinal cells and patient samples, Johns Hopkins Medicine scientists say they found evidence of a new pathway that may contribute to degeneration of the light sensitive tissue at the back of the eye. The findings, they conclude, bring scientists a step closer to developing new drugs for a central vision-destroying complication of diabetes that affects an estimated 750,000 Americans.

Newswise: NIH, NIST researchers use artificial intelligence for quality control of stem cell-derived tissues
Released: 14-Nov-2019 4:05 PM EST
NIH, NIST researchers use artificial intelligence for quality control of stem cell-derived tissues
NIH, National Eye Institute (NEI)

Researchers at the National Eye Institute used artificial intelligence to evaluate stem cell-derived “patches” of retinal pigment epithelium tissue for implanting into the eyes of patients with age-related macular degeneration, a leading cause of blindness.

Newswise: Treatment for common vision disorder does not improve children’s reading skills
18-Oct-2019 3:05 AM EDT
Treatment for common vision disorder does not improve children’s reading skills
NIH, National Eye Institute (NEI)

Results from a clinical trial funded by the National Eye Institute (NEI) show that while vision therapy can successfully treat convergence insufficiency (CI) in children, it fails to improve their reading test scores.

Newswise: Antibody-based eye drops show promise for treating dry eye disease
Released: 11-Oct-2019 4:05 PM EDT
Antibody-based eye drops show promise for treating dry eye disease
University of Illinois at Chicago

Researchers at the University of Illinois at Chicago are the first to identify the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid. They are also the first to demonstrate that patients with dry eye disease experienced reduced signs and symptoms of the condition in response to a new eye drop treatment -- made from pooled human antibodies -- that targets ACPAs.

Newswise: Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial
6-Sep-2019 2:00 PM EDT
Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial
NIH, National Eye Institute (NEI)

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis


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