As part of an Alzheimer's disease prevention trial, Penn Medicine neurodegenerative ethics experts will monitor how learning about their risk of developing Alzheimer's impacts trial participants.
University of Michigan researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease.
A new pre-clinical study by researchers at Temple University found that people who experience chronic sleep disturbance could face an earlier onset of dementia and Alzheimer’s.
A team of scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and San Diego-based American Life Science Pharmaceuticals, Inc., report that cathepsin B gene knockout or its reduction by an enzyme inhibitor blocks creation of key neurotoxic pGlu-Aβ peptides linked to Alzheimer’s disease. Moreover, the candidate inhibitor drug has been shown to be safe in humans.
Getting motivated to exercise can be a challenge, but new research from the University of New Hampshire shows that simply remembering a positive memory about exercise may be just what it takes to get on the treadmill. This is the first study to explore how positive memories can influence future workouts.
March is national Brain Injury Awareness Month. The University of South Carolina has many distinguished neuroscience researchers who study brain injury resulting from stroke, sports and physical injury and cognitive and movement disorders.
As more parents consider whether it’s safe for adolescents to play football, a new Tulane University study of high school players found no link between years of play and any decline in neurocognitive function.
Research from the University of Adelaide has confirmed that a gene linked to intellectual disability is critical to the earliest stages of the development of human brains.
A brain-mapping study of patients with schizophrenia has found that areas associated with the ability to imitate are impaired, providing new support for the theory that deficits in this basic cognitive skill may underlie the profound difficulty with social interactions that characterize the disorder.
A new study in animals shows that using a compound to block the body’s immune response greatly reduces disability after a stroke.
New research by UC San Francisco neuroscientists suggests that the body may get help in fast-changing situations from a specialized brain circuit that causes visual system neurons to fire more strongly during locomotion.
In a series of experiments sparked by fruit flies that couldn’t sleep, Johns Hopkins researchers say they have identified a mutant gene — dubbed “Wide Awake” — that sabotages how the biological clock sets the timing for sleep. The finding also led them to the protein made by a normal copy of the gene that promotes sleep early in the night and properly regulates sleep cycles.
Florida Atlantic University neuroscientist Emmanuelle Tognoli, Ph.D., and J.A. Scott Kelso, Ph.D., neuroscientist and eminent scholar in science, at the Center for Complex Systems and Brain Sciences at FAU, recently published research in the prestigious journal Neuron titled “The Metastable Brain.” The article indicates that metastable dynamics – a subtle blend of integration and segregation in the brain that occurs on multiple levels (cells, brain regions, networks) – underlies the real-time coordination necessary for the brain’s dynamic cognitive, behavioral and social functions.
Anyone with blood pressure that’s higher than the optimal 120/80 mmHg may be more likely to have a stroke, according to a new meta-analysis published in the March 12, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.
University of Adelaide researchers say new insights into how the human brain responds to chronic pain could eventually lead to improved treatments for patients.
Research from McGill University reveals that the brain’s motor network helps people remember and recognize music that they have performed in the past better than music they have only heard. A recent study by Prof. Caroline Palmer of the Department of Psychology sheds new light on how humans perceive and produce sounds, and may pave the way for investigations into whether motor learning could improve or protect memory or cognitive impairment in aging populations. The research is published in the journal Cerebral Cortex.
Traumatic brain injury is a risk factor for epilepsy. A new study published in Oxford Journals’ Cerebral Cortex identifies increased levels of a specific neurotransmitter as a contributing factor. The findings suggest that damage to a specific type of brain cell plays a role in the development of epilepsy after a traumatic brain injury.
Brain imaging using radioactive dye can detect early evidence of Alzheimer's disease that may predict future cognitive decline among adults with mild or no cognitive impairment, according to a 36-month follow-up study led by Duke Medicine.
CHORI Scientists Rhonda Patrick, PhD and Bruce Ames, PhD, find causal link between Vitamin D, serotonin and autism. The findings point towards possible prevention and treatment options.
It may now be possible to identify the first-stage Parkinson’s patients who will go on to develop dementia, according to a study conducted at the Institut universitaire de gériatrie de Montréal by Dr. Oury Monchi, PhD, and his postdoctoral student, Dr. Alexandru Hanganu, MD, PhD, both of whom are affiliated with Université de Montréal. These findings were published in the journal Brain.
What if the use of a product influenced your perception of it, making you even more susceptible to its positive aspects and altering your understanding of its drawbacks? This is precisely what happens with cigarettes in chronic smokers, according to a recent study by the Institut universitaire en santé mentale de Montréal and University of Montreal.
Researchers have found that decision-making accuracy can be improved by postponing the onset of a decision by a mere fraction of a second. The results could further our understanding of neuropsychiatric conditions characterized by abnormalities in cognitive function and lead to new training strategies to improve decision-making in high-stake environments. The study was published in the March 5 online issue of the journal PLoS One.
Researchers at The Scripps Research Institute and Vanderbilt University have created the most detailed 3-D picture yet of a membrane protein linked to learning, memory, anxiety, pain and brain disorders such as schizophrenia, Parkinson’s, Alzheimer’s and autism.
A new study suggests that Alzheimer’s disease may contribute to close to as many deaths in the United States as heart disease or cancer. The research is published in the March 5, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Three promising biomarkers being studied to detect Alzheimer’s disease in its early stages appear to undergo a surprising shift as patients develop symptoms of dementia, researchers at Washington University School of Medicine in St. Louis report.
Johns Hopkins researchers say they have found one way that a recently discovered genetic mutation might cause two nasty nervous system diseases. While the affected gene may build up toxic RNA and not make enough protein, the researchers report, the root of the problem seems to be snarls of defective genetic material created at the mutation site.
An inflammatory protein that triggers a pregnant mouse’s immune response to an infection or other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and humans, new Johns Hopkins-led research suggests.
A new study found that neural circuits in the brain rapidly multitask between detecting and discriminating sensory input, such as headlights in the distance. That’s different from how electronic circuits work, where one circuit performs a very specific task. The brain, the study found, is wired in way that allows a single pathway to perform multiple tasks.
Prehospital stroke alerts by emergency medical services (EMS) personnel can shorten the time to effective treatment with "clot-busting" drugs for patients with stroke, according to a report in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
A pilot study at The University of Texas Health Science Center at Houston (UTHealth) will assess the use of deep brain stimulation (DBS) in the medial forebrain bundle of the brain for treatment-resistant depression.
Veterans exposed to explosions who do not report symptoms of traumatic brain injury (TBI) may still have damage to the brain's white matter comparable to veterans with TBI, according to researchers at Duke Medicine and the U.S. Department of Veterans Affairs.
Whitehead Institute scientists have used a yeast cell-based drug screen to identify a class of molecules that target the amyloid-β (Aβ) peptide involved in Alzheimer’s disease (AD).
Magtein™, a proprietary blend of magnesium –L-threonate, today released a “White Paper” demonstrating the extensive peer-reviewed and published science behind the product’s mechanism of action, its safety and efficacy. The product helps consumers maintain cognitive health, including slowing down but also reversing memory decline as well as addressing the serious health concerns of dementia and Alzheimer’s disease.
A team of researchers from National University of Singapore (NUS) have created the first two-photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual’s potential risk for Parkinson’s disease. The highly sensitive fluorescence probe can detect with high precision the activity of Monoamine Oxidase B (MAO-B), an enzyme that is found in elevated levels in patients with Parkinson’s disease. This innovation paves the way for the development of less costly non-invasive technologies and devices to help monitor the risk and progression of Parkinson’s disease.
Johns Hopkins researchers report that people with chronic insomnia show more plasticity and activity than good sleepers in the part of the brain that controls movement.
For people whose hands shake uncontrollably due to a medical condition, just eating can be a frustrating and embarrassing ordeal – enough to keep them from sharing a meal with others. But a small new study suggests that a new handheld electronic device can help such patients overcome the hand shakes caused by essential tremor.
The role of the so-called “obesity hormone” leptin and hormones used for birth control in the development of multiple sclerosis (MS) is examined in two new studies released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
Prenatal exposure to nicotine could manifest as attention deficit hyperactivity disorder in children born a generation later, according to a new study by Florida State University College of Medicine researchers.
Researchers at the University of Iowa have found that we don’t remember what we hear nearly as well as things we see or touch. In experiments, the team found that memory declined much greater with sounds than with sight or touch, and the forgetfulness began as early as four to eight seconds after being exposed to a sound. The finding suggests our brain may process auditory information differently than visual and tactile information. Results appear in the journal PLoS One.
A simple vision test performed on the sidelines may help determine whether athletes have suffered a concussion, according to a study released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
Unable to walk or even sit up for more than a month, this Santa Fe NM woman is back on her feet after a Cedars-Sinai neurosurgeon was able to successfully repair her cerebrospinal fluid leak.
Researchers created new nerve cells in the brains and spinal cords of living mammals without the need for stem cell transplants to replenish lost cells.
Firefighters who died of heart attacks and other vascular problems such as stroke while on the job were most often doing vigorous physical activity right before the attack, according to a study released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
An updated guideline from the American Academy of Neurology recommends that people with nonvalvular atrial fibrillation, or irregular heartbeat, take oral anticoagulants, a type of blood thinner pill, to prevent stroke. The guideline is published in the February 25, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology. The World Stroke Organization has endorsed the updated guideline.
Researchers at Cedars-Sinai have developed a unique, compact, relatively inexpensive imaging device to “light up” malignant brain tumors and other cancers. The experimental system consists of a special camera designed and developed at Cedars-Sinai and a new, targeted imaging agent based on a synthetic version of a small protein – a peptide – found in the venom of the deathstalker scorpion.
Opiate use triggers changes in the protein RGS9-2 in neurons in the brain's reward center. Repeated use affects analgesic relief and tolerance, as well as addiction.
Researchers have identified a polio-like syndrome in a cluster of children from California over a one-year period, according to a case report released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
Researchers have determined that a small region of the hippocampus known as CA2 is essential for social memory, the ability of an animal to recognize another of the same species. A better grasp of the function of CA2 could prove useful in understanding and treating disorders characterized by altered social behaviors, such as autism, schizophrenia, and bipolar disorder. The findings, made in mice, were published on February 23, 2014, in the online edition of Nature.
An antibody found in the blood of people with multiple sclerosis (MS) may be present long before the onset of the disease and its symptoms, according to a study released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
Results from an ongoing epidemiological study at the University of Kentucky Sanders-Brown Center on Aging suggests a connection between self-reported incidence of memory loss and cognitive memory impairment later in life.
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